5. TUMORS OF LYMPH NODES
1- Primary tumors
Lymphoma:
Malignancy of lymphocytes. (within lymph nodes
or extranodal tissues) , including:
a. Hodgkin’s lymphoma (HL), with important clinical &
histological distinction
b. Non-Hodgkin’s lymphoma (NHLs), comprising
all forms besides HL
Leukemias: usually exhibit widespread involvement of bone
marrow, accompanied by large numbers of circulating tumor
cells
2- Secondary tumors or metastasis: More
frequent than the primary group and occur in the L.N.s
draining cancer. The nodes become enlarged, firm and fixed.
The cut surface is grayish-white
10. (Non-Hodgkin’s Lymphoma (NHL
Malignant neoplasms characterized by proliferation of the cells originating from
lymphoid tissue (lymphocytes, histiocytes and their precursors and
derivatives) .
Classification of NHL
- Based on the clinical behaviour and prognosis:
1- Low-grade NHL:
Small lymphocytic * Follicular small cell
2- Intermediate-grade NHL:
Follicular large cell * Diffuse small cell
3- High-grade NHL:
Immunoblastic * Lymphoblastic * Burkitt’s lymphoma
4- Miscellaneous: Histiocytic lymphoma, Mycosis fungoides ..etc.
11. Follicular lymphoma
1- Section of lymph node.
2- Complete loss of normal lymph node
architecture and
Effaced by follicles formed of monotonous
malignant lymphocytes with deeply staining
pleomorphic hyperchromatic nuclei and thin rim
of cytoplasm.
15. Diffuse Non Hodgkin’s lymphoma
1- Section of lymph node.
2- Complete loss of normal lymph node
architecture and
Effaced by diffuse monotonous malignant
lymphocytes with deeply staining
pleomorphic hyperchromatic nuclei and
thin rim of cytoplasm.
21. Metastasis of lymph node
1- Section of lymph node.
2- Lymph node tissue is partially or
totally replaced by masses or
sheets or irregular glandular
structures, of pleomorphic
hyperchromatic malignant cells
separated by fibrous tissue stroma
22.
23. R espect for self,
Respect for others and
Responsibility for all
.your actions
