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HIV/ AIDS
The 21st century pandemic




            Dr Soumar Dutta
                  CDMO
        Guwahati Refinery Hospital
HIV/AIDS refers to…
 “Acquired Immuno Deficiency Syndrome”
(AIDS) or a set of symptoms and
infections resulting from the damage to the
human immune system caused by the
Human Immunodeficiency Virus (HIV).
This condition progressively reduces the
effectiveness of the immune system and
leaves individuals susceptible to
opportunistic infections and tumors.

                                        2
Basic Definitions And Meanings
What is HIV?
HIV is “Human Immunodeficiency Virus”,it is the
virus that cause AIDS.
Human means that it affects only humans and
lives only in humans.
The virus does not live in
toilets, mosquitoes, cups, spoons, on bed sheets
or towels that people with HIV might have used.
Immunodeficiency refers to lack(deficiency) or
breakdown of immune system. The “immune
system” is the body’s resistance or the body’s
defense force for fighting off infections.     3
History of HIV/AIDS

HIV came from a similar virus found in chimpanzees - SIV.
HIV probably entered the United States around 1970
CDC in 1981 noticed unusual clusters of Kaposi’s sarcoma
in gay men in NY and San Francisco, which led to the
disease to be called GRID (Gay Related Immune
Deficiency).
By 1982 the disease was apparent in heterosexuals and
was renamed AIDS (Acquired Immune Deficiency).
1984- Scientists(Dr. Luc Montagnier, Dr. Robert Gallo)
identify HIV (initially called LAV or HTLV-III) as the cause of
AIDS
1987- AZT is the first drug approved for treating AIDS



             http://www.avert.org/aids-timeline.htm
The Origin of AIDS and HIV
 HIV came from a similar virus found in
 chimpanzees - SIV.
 HIV probably entered the United States
 around 1970.the first recognized case of
 AIDS was in the early 1980s.
 HIV is a lentevirus (slow virus),which in
 turn is a part of a larger group of viruses
 known as retro virus
                                        5
Epidemiology
 Males>females
 Occurs in all ages and ethnic groups
 All areas of the country are affected
 In some city inner areas, as many as 50% of
 males are HIV positive
 AIDS is now the second leading cause of death
 for all men aged 25-44 years
(Unintended injuries is #1 and heart disease is
 #3 for this age group)
                                           6
HIV Transmission
• HIV enters the bloodstream through:

   Open Cuts

   Breaks in the skin

   Mucous membranes

   Direct injection                     7
8
You wont get HIV/Aids from:
• Air you breathe
• Public facilities like buses, telephones, drinking fountains
• Touching, shaking hands or hugging
• Sharing food, plates, cutlery, toiletseats or baths
• Sharing clothing, linen or towels
• Public swimming pools
• Pets or incests like mosquitoes and bedbugs
• Team sports unless there is bleeding wounds
• Restaurants of cafeterias
• Sharing a house with HIV person
• Going to the same school or church
• Kissing
• Donating blood
You might get HIV/ Aids from:
• Having unprotected sex
• Having oral sex with sores in your mouth
• Mother to unborn child
• Using contaminated drug needles
• Sharing razors or other sharp objects and toothbrushes
• Rape or sexual abuse
• Receiving contaminated donor blood
HIV AIDS
When a person's immune system is overwhelmed by AIDS, the symptoms can include:

    extreme weakness or fatigue

    rapid weight loss

    frequent fevers that last for several weeks with no explanation

    heavy sweating at night

    swollen lymph glands

    minor infections that cause skin rashes and mouth, genital, and anal sores

    white spots in the mouth or throat

    chronic diarrhea

    a cough that won't go away

    trouble remembering things
Signs and symptoms

  List of symptoms of HIV/AIDS:
Early infection:
  – More common to develop a brief flu-like illness 2-4 weeks
    after becoming infected. Signs and symptoms may include:
  –   Fever
  –   Headache
  –   Sore throat
  –   Swollen lymph glands
  –   Rash
Signs and symptoms

Later infection :
 May remain symptom-free for eight or nine years or
  more
  You may develop mild infections or chronic
  symptoms such as:
 ◦ Swollen lymph nodes — often one of the first signs of HIV
   infection
 ◦ Diarrhea
 ◦ Weight loss
 ◦ Fever
 ◦ Cough and shortness of breath
At Risk Populations
   Patients who are sexually active
   Homosexual and/or bisexual
   Pregnancy
   Commercial sex workers
   Newly diagnosed with tuberculosis
   Intravenous drug users
   Healthcare workers with exposure
    via needle sticks or other
    occupational exposure injuries
Prevention of Transmission
Avoidance   of direct contact with
sexual fluids
  Abstinence

  Safer   sex & condom use
Infection   control practices
Safer   blood supply
Mother-to-child   (MTC)
IVDU
Prevention
            There's no vaccine to prevent HIV infection and no cure
  for AIDS. Prevention includes educating yourself about HIV and
  avoiding any behavior that allows HIV-infected fluids —
  blood, semen, vaginal secretions and breast milk — into your
  body.
HIV-negative Individual prevention:
  Educate yourself and others.
  Know the HIV status of any sexual partner.
  Use a new latex or polyurethane condom every time you have
  sex.
  Consider male circumcision.
  Use a clean needle.
  Be cautious about blood products in certain countries.
  Get regular screening tests.
  Don't become complacent.
 http://www.mayoclinic.com/health/hiv-aids/DS00005/DSECTION=prevention
Prevention
 HIV positive individual prevention:
  Follow safe-sex practices.
  Tell your sexual partners you have HIV.
  If your partner is pregnant, tell her you have HIV.
  Tell others who need to know.
  Don't share needles or syringes.
  Don't donate blood or organs.
  Don't share razor blades or toothbrushes.
  If you're pregnant, get medical care right away.


http://www.mayoclinic.com/health/hiv-aids/DS00005/DSECTION=prevention
Prevention Of HIV/AIDS
There's no vaccine to prevent HIV infection and no cure for AIDS.
  Prevention includes educating yourself about HIV and avoiding any
  behavior that allows HIV-infected fluids — blood, semen, vaginal
  secretions and breast milk — into your body.
HIV-negative Individual prevention:
  Educate yourself and others.
  Know the HIV status of any sexual partner.
  Use a new latex or polyurethane condom every time you
  have sex.
  Consider male circumcision.
  Use a clean needle.
  Be cautious about blood products.
  Get regular screening tests.

                                                              18
Prevention Of HIV/AIDS
HIV positive individual prevention:
 Follow safe-sex practices.
 Tell your sexual partners you have HIV.
 If your partner is pregnant, tell her you have HIV.
 Tell others who need to know.
 Don't share needles or syringes.
 Don't donate blood or organs.
 Don't share razor blades or toothbrushes.
 If you're pregnant, get medical care right away.
                                                19
ABC Strategy

 Avoid exposure      bstinence
                   Mutual faithfulness




 Reduce exposure    e faithful
                   (Partner reduction)



  Block exposure
    effectively      ondom use
                                     20
21
Reference List
     Vistacion, T. (2005). Principles of microbiology.
           Salvation.

     WHO. (2009, August 15). http://aids.about.com.
        Retrieved August 15, 2009, from World Health
        Organisation: http://aids.about.com

     Kevin, H. (c2008.). Health issues confronting minority
          men who have sex with men . New York
          :Springer.

     http://www.mayoclinic.com




                                                              22

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Class activity 11 march 2012

  • 1. HIV/ AIDS The 21st century pandemic Dr Soumar Dutta CDMO Guwahati Refinery Hospital
  • 2. HIV/AIDS refers to… “Acquired Immuno Deficiency Syndrome” (AIDS) or a set of symptoms and infections resulting from the damage to the human immune system caused by the Human Immunodeficiency Virus (HIV). This condition progressively reduces the effectiveness of the immune system and leaves individuals susceptible to opportunistic infections and tumors. 2
  • 3. Basic Definitions And Meanings What is HIV? HIV is “Human Immunodeficiency Virus”,it is the virus that cause AIDS. Human means that it affects only humans and lives only in humans. The virus does not live in toilets, mosquitoes, cups, spoons, on bed sheets or towels that people with HIV might have used. Immunodeficiency refers to lack(deficiency) or breakdown of immune system. The “immune system” is the body’s resistance or the body’s defense force for fighting off infections. 3
  • 4. History of HIV/AIDS HIV came from a similar virus found in chimpanzees - SIV. HIV probably entered the United States around 1970 CDC in 1981 noticed unusual clusters of Kaposi’s sarcoma in gay men in NY and San Francisco, which led to the disease to be called GRID (Gay Related Immune Deficiency). By 1982 the disease was apparent in heterosexuals and was renamed AIDS (Acquired Immune Deficiency). 1984- Scientists(Dr. Luc Montagnier, Dr. Robert Gallo) identify HIV (initially called LAV or HTLV-III) as the cause of AIDS 1987- AZT is the first drug approved for treating AIDS http://www.avert.org/aids-timeline.htm
  • 5. The Origin of AIDS and HIV HIV came from a similar virus found in chimpanzees - SIV. HIV probably entered the United States around 1970.the first recognized case of AIDS was in the early 1980s. HIV is a lentevirus (slow virus),which in turn is a part of a larger group of viruses known as retro virus 5
  • 6. Epidemiology Males>females Occurs in all ages and ethnic groups All areas of the country are affected In some city inner areas, as many as 50% of males are HIV positive AIDS is now the second leading cause of death for all men aged 25-44 years (Unintended injuries is #1 and heart disease is #3 for this age group) 6
  • 7. HIV Transmission • HIV enters the bloodstream through: Open Cuts Breaks in the skin Mucous membranes Direct injection 7
  • 8. 8
  • 9. You wont get HIV/Aids from: • Air you breathe • Public facilities like buses, telephones, drinking fountains • Touching, shaking hands or hugging • Sharing food, plates, cutlery, toiletseats or baths • Sharing clothing, linen or towels • Public swimming pools • Pets or incests like mosquitoes and bedbugs • Team sports unless there is bleeding wounds • Restaurants of cafeterias • Sharing a house with HIV person • Going to the same school or church • Kissing • Donating blood
  • 10. You might get HIV/ Aids from: • Having unprotected sex • Having oral sex with sores in your mouth • Mother to unborn child • Using contaminated drug needles • Sharing razors or other sharp objects and toothbrushes • Rape or sexual abuse • Receiving contaminated donor blood
  • 11. HIV AIDS When a person's immune system is overwhelmed by AIDS, the symptoms can include: extreme weakness or fatigue rapid weight loss frequent fevers that last for several weeks with no explanation heavy sweating at night swollen lymph glands minor infections that cause skin rashes and mouth, genital, and anal sores white spots in the mouth or throat chronic diarrhea a cough that won't go away trouble remembering things
  • 12. Signs and symptoms List of symptoms of HIV/AIDS: Early infection: – More common to develop a brief flu-like illness 2-4 weeks after becoming infected. Signs and symptoms may include: – Fever – Headache – Sore throat – Swollen lymph glands – Rash
  • 13. Signs and symptoms Later infection :  May remain symptom-free for eight or nine years or more You may develop mild infections or chronic symptoms such as: ◦ Swollen lymph nodes — often one of the first signs of HIV infection ◦ Diarrhea ◦ Weight loss ◦ Fever ◦ Cough and shortness of breath
  • 14. At Risk Populations  Patients who are sexually active  Homosexual and/or bisexual  Pregnancy  Commercial sex workers  Newly diagnosed with tuberculosis  Intravenous drug users  Healthcare workers with exposure via needle sticks or other occupational exposure injuries
  • 15. Prevention of Transmission Avoidance of direct contact with sexual fluids Abstinence Safer sex & condom use Infection control practices Safer blood supply Mother-to-child (MTC) IVDU
  • 16. Prevention There's no vaccine to prevent HIV infection and no cure for AIDS. Prevention includes educating yourself about HIV and avoiding any behavior that allows HIV-infected fluids — blood, semen, vaginal secretions and breast milk — into your body. HIV-negative Individual prevention: Educate yourself and others. Know the HIV status of any sexual partner. Use a new latex or polyurethane condom every time you have sex. Consider male circumcision. Use a clean needle. Be cautious about blood products in certain countries. Get regular screening tests. Don't become complacent. http://www.mayoclinic.com/health/hiv-aids/DS00005/DSECTION=prevention
  • 17. Prevention HIV positive individual prevention: Follow safe-sex practices. Tell your sexual partners you have HIV. If your partner is pregnant, tell her you have HIV. Tell others who need to know. Don't share needles or syringes. Don't donate blood or organs. Don't share razor blades or toothbrushes. If you're pregnant, get medical care right away. http://www.mayoclinic.com/health/hiv-aids/DS00005/DSECTION=prevention
  • 18. Prevention Of HIV/AIDS There's no vaccine to prevent HIV infection and no cure for AIDS. Prevention includes educating yourself about HIV and avoiding any behavior that allows HIV-infected fluids — blood, semen, vaginal secretions and breast milk — into your body. HIV-negative Individual prevention: Educate yourself and others. Know the HIV status of any sexual partner. Use a new latex or polyurethane condom every time you have sex. Consider male circumcision. Use a clean needle. Be cautious about blood products. Get regular screening tests. 18
  • 19. Prevention Of HIV/AIDS HIV positive individual prevention: Follow safe-sex practices. Tell your sexual partners you have HIV. If your partner is pregnant, tell her you have HIV. Tell others who need to know. Don't share needles or syringes. Don't donate blood or organs. Don't share razor blades or toothbrushes. If you're pregnant, get medical care right away. 19
  • 20. ABC Strategy Avoid exposure bstinence Mutual faithfulness Reduce exposure e faithful (Partner reduction) Block exposure effectively ondom use 20
  • 21. 21
  • 22. Reference List Vistacion, T. (2005). Principles of microbiology. Salvation. WHO. (2009, August 15). http://aids.about.com. Retrieved August 15, 2009, from World Health Organisation: http://aids.about.com Kevin, H. (c2008.). Health issues confronting minority men who have sex with men . New York :Springer. http://www.mayoclinic.com 22

Editor's Notes

  1. Dr. Robert Gallo of the National Cancer Institute had isolated the virus which caused AIDS. Dr. Luc Montagnier Pasteur Institute in ParisThe scientific protagonists finally agreed to share credit for the discovery of HIV, and in 1986, both the French and the US names (LAV and HTLV-III) were dropped in favor of the new term human immunodeficiency virus
  2. ABCs of prevention: A = abstinence, B = be faithful, C = use condoms (correctly & cosistently)