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GUIDE TO AUTHORS

Table of Contents
                                                                                New Membership Category introduced for Members in
About the Journal                                                 p1            Training
Preparation of Manuscripts                                        p2            Trainees in nephrology up to the age of 37 years are now
  Content Types                                                   p2            encouraged to apply to become ISN Members in Training at a
  Format of Manuscripts                                           p3            greatly reduced annual membership rate of US$ 70 (all benefits
  Figures and Tables                                              p4            included). Eligible individuals must submit a copy of a valid
  Supplementary Information                                       p5            form of identification stating their date of birth as well as a proof
Submission and Publication                                        p5            of their current training status to the ISN Global Headquarters
Appendix                                                          p6            together with their completed application.
                                                                                http://www.nature.com/isn/society/membership/isn_20048.html




About the Journal
                                                                              context. These will form a research tool for clinical and ba-
                                                                              sic investigators.
PUBLICATION CHARGES (Do not apply to invited authors)
                                                                          •   Editorials that highlight important issues in international ne-
                                                                              phrology
Page charges
                                                                          •   Nephrology sans Frontieres - occasional short articles that
Manuscripts accepted for publication in Kidney International will
                                                                              discuss matters of local interest to nephrologists around the
incur page charges to cover, in part, the cost of publication. A
                                                                              world, but which we feel need to be known by nephrologists
charge of $74 will be issued for each journal page.
                                                                              world-wide
Color charges                                                             •   Short reviews on hot topics and in depth reviews about ma-
All figures that are submitted as color artwork must be published in          jor issues in renal research.
color. The authors will be expected to contribute towards the cost        •   Controversial discussions on renal therapeutics or diagno-
of color art .The cost for reproducing color artwork in print is $530         sis written by two opposing authorities
per page. Color figures will be set close to the citation and in the      •   State of the Art teaching materials including clinico-
best possible position. Figure re-ordering cannot be undertaken at            pathological conferences where eminent clinicians discuss
proof stage to reduce the number of pages featuring color artwork.            difficult or interesting cases illustrated by multiple pathol-
                                                                              ogy, imaging studies and charts
Upon acceptance authors must fill in the artwork form available at        •   Images in Nephrology which are presentations of interest-
http://mc.manuscriptcentral.com/societyimages/ki/KI%20Artwork%                ing images in renal pathology, radiology chosen for their il-
20Form.pdf                                                                    lustrative nature or simply for their esthetic qualities.
                                                                          •   Issues of importance to the international renal community
Offprints                                                                     including the politics of funding; of organ transplantation, of
Offprints may be ordered using the order form available for down-             adequacy of dialysis, of world-wide affordability of end
load with the proofs.                                                         stage renal care and many other topical issues.
                                                                          •   Journal Club are synopses that bring you the latest re-
                                                                              search highlights from across a wide spectrum of journals
IMPACT FACTOR                                                                 in fields relevant to renal research
2009 Impact Factor 6.193*                                                 •   Book Reviews
3/63 Urology and Nephrology

*2009 Journal Citation Reports (Thomson Reuters, 2010)                   ABSTRACTED/ INDEXED IN
                                                                          •   Index Medicus/Medline
ISSN                                                                      •   Science Citation Index
ISSN: 0085-2538                                                           •   Current Contents/Life Sciences
EISSN: 1523-1755                                                          •   Current Contents/Clinical Medicine
                                                                          •   SciSearch
                                                                          •   BIOSIS
FREQUENCY                                                                 •   Chemical Abstracts
Printed twice a month. Advance online Publication once a week.            •   EMBASE/Excerpta Medica
                                                                          •   Reference Update
                                                                          •   CABS
SCOPE                                                                     •   Biological Abstracts
Kidney International aims to inform the renal researcher and the          •   Global Health
practicing nephrologist on all aspects of renal research, including:      •   MDX Health Digest
  •     The latest clinical studies on emerging developments in re-       •   EBSCO
        nal medicine.                                                     •   Adonis
  •     The highest level of original research studies in clinical and    •   PASCAL
        basic renal research.
  •     In each issue, some articles will be highlighted by commen-
        taries that aim to put these studies in the appropriate




                                                   REVISED March 15, 2011
GUIDE TO AUTHORS

                                                                         empt. A list of acceptable registries is available on the ICMJE web-
Preparation of manuscripts                                               site (http://www.icmje.org). Each manuscript will be checked upon
                                                                         submission to determine whether the study has been appropriately
                                                                         registered. All studies which began enrolling patients after July 1,
Manuscripts that do not adhere to the following instructions             2005 must have been registered before patient enrollment. Any trial
will be returned to the corresponding author for technical               which was still seeing patients on September 13, 2005, should
revision before undergoing peer review.                                  have been registered before September 13, 2005. If the trial was
                                                                         complete before September 13, 2005, the study should be regis-
                                                                         tered before submission.

Content Types                                                            Reporting of randomized controlled trials should follow the guide-
                                                                         lines of The CONSORT Statement
The types of manuscripts accepted by KI are: (1) Review, (2) Mini-       (http://www.consortstatement.org).
review, (3) Original Article, (4) Commentary, (5) Technical Note,
(6) Letter to the Editor (7), Editorial (8), Nephrology Image, (9)
Make Your Diagnosis, (10) Book Review, (11) ISN Forefronts in            (4) Commentary [only by invitation of Editors]
Nephrology, ISN Nexus, Meeting Report.                                   Word limit: 1500 words (8,400 characters) maximum including
                                                                         spaces and abstract but excluding references
                                                                         Title: 115 characters maximum including spaces
                                                                         Abstract: 75 words (420 characters) maximum
 (1) Review                                                              References: 10 maximum including the article discussed
Word limit: 5,000 words (28,000 characters) maximum including            Figures/tables: 1 figure required (will be redrawn)
spaces and abstract but excluding references, tables and figures.        Commentaries discuss a paper published in a specific issue and
Abstract: 250 words (1500 characters) maximum including spaces           should set the problems addressed by the paper in the wider con-
References: no maximum                                                   text of the field. Authors will not be charges for color images.
Figures/tables: 3 images or figures required
Disclosure statement required (see page 3 for details)                   (5) Technical Note
Reviews are comprehensive analyses of specific topics in nephrol-        Word limit: 1500 words (8,400 characters) maximum including
ogy that are usually solicited by the Editors. Proposals for reviews     abstract but excluding references, tables and figures.
may be submitted; however, in this case authors should only send         Abstract: 250 words (1500 characters) maximum including spaces
an outline of the proposed paper for initial consideration. Both         References: 20 maximum
solicited and unsolicited review articles will undergo peer review       Disclosure statement required (see page 3 for details)
prior to acceptance. Kidney International will cover charges for         Examples of appropriate subject matter include descriptions of new
color images for articles invited by the Editors, and for images in      laboratory or clinical methods, new apparatus, or critical modifica-
which color was added by the journal.                                    tions of established techniques. Organization of Technical Notes
                                                                         should be the same as for regular manuscripts except that section
(2) Minireview                                                           headings should be omitted.
Word limit: 3000 words (16,800 characters) maximum including
spaces and abstract but excluding references, tables and figures.        (6) Letter to the Editor
Abstract: 250 words (1500 characters) maximum including spaces           Word limit: 250 words (1500 characters) maximum including
References: 20 maximum                                                   spaces
Figures/tables: 2 images or figures required                             Abstract: no abstract required for this manuscript type
Disclosure statement required (see page 3 for details)                   References: 4 maximum
Minireviews of topical and highly focused subjects are usually           Figures/ tables: Up to 1
solicited by the Editors. Proposals for minireviews may be submit-       Letters to the Editor will be considered for publication, subject to
ted; however, in this case authors should only send an outline of        editing. Letters must contain information critical to a certain area or
the proposed paper for initial consideration. Both solicited and         must be confirmatory of data recently published in Kidney Interna-
unsolicited review articles will undergo peer review prior to accep-     tional. A Letter must reference the original source, and a Response
tance. Kidney International will cover charges for color images for      to a Letter must reference the Letter in the first few paragraphs, as
articles invited by the Editors, and for images in which color was       well as the original source. Letters can use an arbitrary title, but a
added by the journal.                                                    Response must cite the title of the Letter: e.g. Response to [title of
                                                                         Letter]. All Letters must contain a title page including title, all au-
(3) Original Article                                                     thors’ names and affiliations, and corresponding author contact
Sub-categories: Basic Research, Clinical Research, Clinical              information.
Trials
Word limit: 4000 words (22,400 characters) maximum including             (7) Editorial [only by invitation of Editors]
spaces and abstract but excluding references, tables and figures.        Word Limit: 1600 words (8,960 characters) maximum including
Abstract: 250 words (1500 characters) maximum including spaces.          spaces
Results: Include headings about what is being tested in each indi-       Abstract: no abstract required for this manuscript type
vidual experiment.                                                       References: 5 maximum
References: no limit                                                     Proposals for Editorials may be submitted; authors should only
Figures/ tables: no limit. However, additional figures and tables        send an outline of the proposed paper for initial consideration.
may be considered as supplements for Web-only publication.
Disclosure statement required (see page 3 for details)                   (8) Nephrology Image
Full-length reports of current research in either basic or clinical      Word limit: Title: 70 characters including spaces; text: 300 words
science.                                                                 (1700 characters) including spaces
                                                                         Figures: 2 single panel figures maximum. No multi-part figures
Special Notice Regarding Clinical Trials:                                allowed.
Kidney International encourages the submission of manuscripts            References: none
reporting results of clinical trials and must be submitted under a       Abstract: no abstract required for this manuscript type
separate category under Original Articles - Clinical Trials. It is im-   Illustrative images that are unique or highly illustrative of specific
portant to follow the recommendations of the International Commit-       occurrences in Nephrology such as renal pathology, radiology,
tee of Medical Journal Editors (ICMJE), which requires that “any         specific skin lesions, etc. They should be accompanied by a brief
research project that prospectively assigns human subjects to            one-paragraph description of relevant clinical information. Article
intervention and comparison groups to study the cause-and-effect         must fit onto one page. You will be asked to cut text or part of your
relationship between a medical intervention and a health outcome”        figure in the proof if article is longer than one page.
must be registered before the start of patient enrollment. Trials in
which the primary goal is to determine pharmacokinetics are ex-
                                                        REVISED March 15, 2011                                                                2
GUIDE TO AUTHORS

(9) Make Your Diagnosis                                                           Title Page
Word limit: Title: 70 characters; The Case (page 1): 245 words                    Abstract
(1400 characters); The Diagnosis (page 2): 405 words (2300 char-                  Introduction
acters). Word limits include spaces but exclude references, tables                Results
and figures.                                                                      Discussion
Abstract: no abstract required for this manuscript type                           Methods
References: 3 maximum                                                             Disclosure
Figures/tables: 1 single panel figures maximum per page                           References
This column provides readers with an opportunity to make clinical                 Acknowledgements
diagnoses based on an image accompanied by the history and
physical exam, all of which will be on the first page. The second
page will include the answers, a brief discussion and any other            Abbreviations
relevant follow up images and laboratory data.                             Abbreviations should be defined at the first mention in the text and
                                                                           in each table and figure. For a list of standard abbreviations, please
(10) Book Review                                                           consult the Council of Biology Editors Style Guide (available from
Word limit: 500-1000 words including spaces, excluding references          the Council of Science Editors, 9650 Rockville Pike, Bethesda, MD
Abstract: no abstract required for this manuscript type                    20814) or other standard sources. Write out the full term for each
References: 3 maximum                                                      abbreviation at its first use unless it is a standard unit of measure.
Book Reviews alert readers to work that is potentially important to        Refrain from overuse of abbreviations.
the field of nephrology, and puts it in context with the nephrology
literature. Book Reviews should follow this outline: (a) exact title of    Disclosure
book, full name(s) of author(s), publisher’s name, publication date,       For original articles and reviews only, the submitting author must
number of pages and price, (b) summary of the content (general             include a disclosure statement in the body of the manuscript. The
discussion of what the book covers and its major topics; NOT a             statement will describe all of the authors’ relationships with compa-
chapter by chapter summary), (c) discussion of author(s) (for ex-          nies that may have a financial interest in the information contained
ample, background, experience, why they are qualified to write the         in the manuscript. This information should be provided under the
book and whether they present a certain view), (d) strong points of        heading titled ‘Disclosure,’ which should appear after the ‘Methods’
the book, (e) weak points of the book, (f) identification of the audi-     section and before the ‘References’ section. The absence of any
ence of this book and the background needed for the reader to              interest to disclose must also be stated. In addition, any financial
understand its contents, (g) discussion of why one should or               interests must be detailed in the Financial Disclosure form, which
should not buy the book, and if yes, for what purpose (as a text, a        will be provided to the corresponding author upon acceptance for
reference, etc.), (h) comparison to other books in the field, and (i) if   distribution to each author.
possible, a “quotable quote” or annotation regarding the book.
                                                                           References
(11) ISN Forefronts in Nephrology, ISN Nexus, Meeting Report               References should be listed in order of appearance (Vancouver
[only by invitation of Editors]                                            style). In the text, number references in order of appearance using
Word limit: To be determined in consultation with Editors                  Arabic numerals (e.g. 1, 2, 3) in parentheses for citations. The
Abstract: 150 words (1500 characters) maximum including spaces,            reference list (starting on a separate page) should contain the ref-
excluding references and figures.                                          erences in the order in which they are cited in the text. Only pub-
References: no maximum                                                     lished works (as well as manuscripts already accepted for
Figures/tables: at least 1 image or figure                                 publication) which are referred to in the text should be listed in the
Disclosure statement required (see page 3 for details)                     reference list. The reference list must not contain any abstract
These authoritative proceedings of specific topics in nephrology           citations, unpublished observations, personal communications, etc.
are usually solicited by the Editors. Proposals may be submitted;          Kindly cite such sources solely within the text (in parentheses), not
authors should only send an outline of the proposed paper for              in the reference list. Do not list more than three authors per refer-
initial consideration. Both solicited and unsolicited articles will un-    ence. Should there be four or more, please include only the first
dergo peer review prior to acceptance. Kidney International will           three followed by ‘‘et al.’’
cover charges for color images in articles invited by the Editors.
                                                                           The following examples demonstrate correct reference style:
Format of Manuscripts                                                      Journal articles:
                                                                           Fan SL-S, Almond MK, Ball E, et al. Pamidronate therapy as pre-
GENERAL FORMAT                                                             vention of bone loss following renal transplantation. Kidney Int
Manuscripts must be typed in English and double-spaced. All text           2000; 57: 684–690.
including legends, footnotes, tables and references are to be on
one side of the page only. All manuscript pages must be num-               Supplement articles:
bered.                                                                     Fogo AB. Glomerular hypertension abnormal glomerular growth,
                                                                           and progression of renal diseases. Kidney Int 2000; 57 (Suppl 75):
Title page                                                                 S15–S21.
This should include (a) the complete manuscript title; (b) all au-
thors’ full names (listed as first name, middle initial, last name),       Books:
highest academic degrees, and affiliations; (c) the name and ad-           Lameire N, Mehta RL (eds.). Complications of Dialysis. Marcel
dress for correspondence, fax number, telephone number, and e-             Dekker, Inc.: New York, 2000.
mail address; and (d) the sources of support that require acknowl-
edgment. A running headline of no more than 50 characters (in-             Articles in books:
cluding spaces) should be supplied.                                        Weidner N, Buckalew VM Jr. Sickle cell anemia, sickle cell trait,
                                                                           and polycythemic states, in Renal Pathology (vol 2), eds. Tisher
Abstract and Keywords                                                      CC, Brenner BM. JB Lippincott Company: Philadelphia, 1989, pp
The abstract should be no longer than 1500 characters including            1417–1436.
spaces, stating the main problem, methods, results, and conclu-
sions. There should be no subheadings in the abstract. It must be
factual and comprehensive. The use of abbreviations and acro-              ORIGINALITY
nyms should be limited and general statements (e.g. ‘‘the signifi-         A submitted manuscript must be an original contribution not previ-
cance of the results is discussed’’) should be avoided.                    ously published (except as an abstract or preliminary report), must
                                                                           not be under consideration for publication elsewhere, and, if ac-
Text                                                                       cepted, must not be published elsewhere in a similar form, in any
The manuscript should be organized under the following nine                language, without the consent of the ISN. Each person listed as an
headings:                                                                  author is expected to have participated in the study to a significant

                                                         REVISED March 15, 2011                                                                3
GUIDE TO AUTHORS

extent and agrees with submission of the paper for publication.           Journal style
Although the editors and referees make every effort to ensure the         As the electronic submission will provide the basic material for
validity of published manuscripts, the final responsibility rests with    typesetting, it is important that papers are prepared in the general
the authors, not with Kidney International, its editors, the Interna-     editorial style of the journal.
tional Society of Nephrology or Nature Publishing Group.                       1. For information on labeling of figures, see the artwork
                                                                               guidelines: http://www.nature.com/aj/artworkguidelines.pdf
INFORMED CONSENT AND ETHICS                                                    2. Do not make rules thinner than 1 pt (0.36mm)
When reporting experiments on human subjects, indicate whether                 3. Use a coarse hatching pattern rather than shading for tints
the procedures were in accordance with the ethical standards of                in graphs
the responsible committee on human experimentation (institutional              4. Color should be distinct when used as an identifying tool
or regional) or with the Helsinki Declaration of 1975 (and as re-              5. Use SI units throughout
vised in 1983). Include any Institutional Review Board or Animal               6. Spaces, not commas, should be used to separate thou-
Care and Use Committee protocol numbers as warranted by ex-                    sands
perimental design.                                                             7. Abbreviations should be preceded by the words for which
                                                                               they stand in the first instance of use in the text. Overuse of
                                                                               abbreviations in the text is discouraged
GUIDELINES FOR STUDIES OF DNA POLYMORPHISMS
                                                                               8. No abbreviations should be used in the title or the
For case-control studies investigating associations between DNA
                                                                               abstract
sequence polymorphisms and renal phenotypes the following re-
                                                                               9. The abstract should be written as a single paragraph; do
view criteria will be considered in prioritizing manuscripts for publi-
                                                                               not include headings
cation:
                                                                               10. Text should be double spaced with a wide margin
                                                                               11. At the first mention of a manufacturer, the town (state if
1. Adequate sample size and explicit power calculation are re-
                                                                               USA) and country should be provided
quired for all submitted manuscripts. Negative studies have to be
adequately powered in order to be considered for publication.

2. Appropriate correction of p-values for multiple comparisons is         FILE FORMATS
also required. In many cases this will involve calculation of empiric     Manuscripts
p-values by permutation.                                                  Use Microsoft Word for the text of your article. Files in MS Office
                                                                          2007 format cannot be accepted for publication. For instructions on
3. Typing multiple markers within a locus of interest is preferred        how to save MS Office 2007 files in a format acceptable for publi-
over studies that examine a single polymorphism. Defining risk            cation, please see the Appendix.
haplotypes and performing haplotypic association tests is encour-
aged.                                                                     Figures, Images and Tables
                                                                          Figures and images should be labeled sequentially, numbered and
4. Assessment and correction for possible population stratification       cited in the text. Figures should be referred to specifically in the text
are strongly encouraged, unless the analysis involves a method            of the paper but should not be embedded within the text. Each
that is robust to stratification effects (eg. transmission-               table should be double-spaced on a separate sheet and numbered
disequilibrium testing).                                                  consecutively in the order of first citation in the text. Make sure that
                                                                          each table is cited in the text. Tables must be submitted as Micro-
5. Replication of the association in an independent cohort is re-         soft Word documents. Do not use internal horizontal and vertical
quired for new association findings.                                      lines. The use of three-dimensional histograms is strongly discour-
                                                                          aged when the addition of the third dimension gives no extra infor-
6. Priority will be given to studies that demonstrate a specific effect   mation. If a table or figure has been published before, the authors
of the associated polymorphism on the expression or function of           must obtain written permission to reproduce the material in both
the relevant genes. A convincing biological validation will be con-       print and electronic formats from the copyright owner and submit
sidered in lieu of the replication requirement.                           the permission with the manuscript. This rule applies for quotes,
                                                                          illustrations and other materials taken from previously published
MICROARRAY DATA                                                           works not in the public domain. The original source should be cited
Authors submitting manuscripts containing microarray data must            in the figure caption or table footnote.
submit the data to the Gene Expression Omnibus
(http://www.ncbi.nlm.nih.gov/geo/) or ArrayExpress                        Legends and Titles
(http://www.ebi.ac.uk/arrayexpress/) databases, and provide the           Legends must be submitted for all figures and images, and titles for
accession number(s) upon submission to the journal. The data              all tables. They should be brief and specific, double spaced, and
must be MIAME-compliant, with all variables completed.                    placed on a separate sheet titled ‘Titles and legends’ after the Ref-
                                                                          erence section. Use scale markers in the image for electron micro-
                                                                          graphs and indicate the type of stain used. Place explanatory
STYLE                                                                     matter of tables in the footnotes rather than in the titles.
The American Medical Association Manual of Style (9th edition),
Stedman’s Medical Dictionary (27th edition) and Merriam Web-              ARTWORK GUIDELINES
ster’s Collegiate Dictionary (10th edition) should be used as stan-       Detailed guidelines for submitting artwork can be found by
dard references. Refer to drugs and therapeutic agents by their           downloading the guidelines PDF:
accepted generic or chemical name, and do not abbreviate them (a          http://www.nature.com/aj/artworkguidelines.pdf. Using the guide-
proprietary name may be given only with the first use of the ge-          lines, please submit production quality artwork with your submis-
neric name). Code numbers should be used only when a generic              sion. At submission, all figures must be high enough quality (no
name is not yet available (the chemical name and a figure giving          less than 300 dpi) to be assessed in the peer review process. We
the chemical structure of the drug are required). Copyright or trade      prefer artwork to be submitted in eps, .jpg, .ppt, or .tif format. pdf or
names of drugs should be capitalized and placed in parentheses            Corel Draw format is discouraged. If you have not followed the
after the name of the drug. Names and locations (city and state in        artwork guidelines, we will require artwork to be resubmitted if your
USA; city and country outside USA) of manufacturers of drugs,             paper is accepted for publication.
supplies, or equipment cited in a manuscript are required to com-
ply with trademark law and should be provided in parentheses.                  Minimum Resolutions: Halftone images 300 dpi (dots per inch)
Quantitative data may be reported in the units used in the original            Color images 300 dpi saved as CMYK
measurement, but SI units are preferred, including those applica-              Images containing text 400 dpi
ble to body weight, mass (weight) and temperature.                             Line art 1000 dpi




                                                         REVISED March 15, 2011                                                                  4
GUIDE TO AUTHORS

Sizes:                                                                  mentary information, use a 256-color palette. Please consider the
     Figure Width – single image                                        use of lower specification for all of these points if the supplemen-
     86mm (Should be able to fit into a single column of the            tary information can still be represented clearly. Our recommended
     printed journal)                                                   maximum data rate is 150 KB/s.

     Figure Width – multi-part image                                    The number of files should be limited to eight, and the total file size
     178mm (Should be able to fit into a double column of the           should not exceed 8 MB. Individual files should not exceed 1 MB.
     printed journal)                                                   Please seek advice from the editorial office before sending files
                                                                        larger than our maximum size to avoid delays in publication.
     Text Size
     8 point (Should be readable after reduction – avoid large type     Further questions about the submission or preparation of supple-
     or thick lines) Line Width Between 0.5 and 1 point                 mentary information should be directed to the editorial office.


Color Artwork Charges                                                   Open Access
Artwork provided in color upon submission must be printed in
                                                                        Upon submission of an original research paper, authors can indi-
color, and the author must agree to pay for the cost of printing said
                                                                        cate within the manuscript tracking system whether they wish to
artwork in color. The cost to produce color artwork is $530 per
                                                                        pay an article processing charge to allow their article to be pub-
page. Color figures will be set close to the citation and in the best
                                                                        lished open access. The article processing charge is
possible position. Figure re-ordering cannot be undertaken at proof
                                                                        £2,000/$3,000/€2,400 (plus VAT where applicable) and
stage to reduce the number of pages featuring color artwork.
                                                                        can be paid via credit card or by requesting an invoice be raised.

                                                                        By paying this article processing charge, authors are permitted to
                                                                        post the final, published pdf of their article on a website, institu-
Supplementary Information                                               tional repository or other free public server immediately on publica-
                                                                        tion. Upon acceptance, authors must fill out and send back a
Supplementary information is peer-reviewed material directly rele-      payment form. This is mandatory and failure to send in the pay-
vant to the conclusion of an article that cannot be included in the     ment form along with the Licence to Publish form will result in the
printed version owing to space or format constraints. It is posted on   article being published as a standard paper behind access control.
the journal’s web site and linked to the article when the article is    (Note: US Government employees must use this license to publish
published and may consist of data files, graphics, movies or exten-     form.)
sive tables. The printed article must be complete and self-
explanatory without the supplementary information. Supplementary        The licence to publish form has been amended to offer authors the
information enhances a reader’s understanding of the paper, but is      choice of which licence to use on their paper and these choices are
not essential to that understanding. Supplementary information          described below:
must be supplied to the editorial office in its final form for peer
review. On acceptance, the final version of the peer-reviewed sup-      The first is the Creative Commons Attribution-Noncommercial-No
plementary information should be submitted with the accepted            Derivative Works 3.0 Unported Licence and allows readers to
paper. To ensure that the contents of the supplementary informa-        download the article and share it with others as long as they men-
tion files can be viewed by the editor(s), referees and readers,        tion the author and link back to the original article. The article can-
please also submit a ‘read-me’ file containing brief instructions on    not be changed in any way or used commercially.
how to use the file.
                                                                        The second is the Creative Commons Attribution Noncommercial
If your manuscript or any significant part of it has been under con-    Share Alike 3.0 Unported Licence and allows readers to alter,
sideration for publication elsewhere, or has appeared elsewhere in      transform, or build upon the article and then distribute the resulting
a manner that could be construed as a prior or duplication publica-     work under the same or similar licence to this one. The work must
tion of the same, or very similar, work, the said material must be      be attributed back to the original author and commercial use is not
included and marked appropriately as a supplemental file.               permitted.

                                                                        For further information please see:
                                                                        http://www.nature.com/ki/for_authors.html
Supplying supplementary information files
Authors should ensure that supplementary information is supplied
in its FINAL format as it is not copy edited and will appear online     Submission and publication
exactly as originally submitted. It cannot be altered, nor new sup-
plementary information added, after the paper has been accepted
for publication. Please supply the supplementary information via        SUBMISSION OF PAPERS
the electronic manuscript submission and tracking system, in an         If you are ready to submit an article please visit the Online Submis-
acceptable file format (see below). Authors should: include a text      sion page: http://mc.manuscriptcentral.com/ki
summary (no more than 50 words) to describe the contents of             All text should be submitted in Microsoft Word (.doc) and fig-
each file; identify the types of files (file formats) submitted and     ures as .tif or .jpg files
include the text ‘Supplementary information is available at Kidney      Figures appearing in the online version of manuscripts will be pub-
International’s website’ at the end of the article and before the       lished in 72 dpi as is standard for all .pdf files on the internet. All
references.                                                             figures published in print are at least 300 dpi.

Accepted file formats
Quick Time files (.mov), graphical image files (.gif), HTML files
(.html), MPEG movie files (.mpg), JPEG image files (.jpg), sound        LICENSE TO PUBLISH
files (.wav), plain ASCII text (.txt), MS Word documents (.doc),        The corresponding author must complete and sign the License to
Postscript files (.ps), MS Excel spreadsheet documents (.xls) and       Publish form upon acceptance of the manuscript and return it to the
PowerPoint files (.ppt). We cannot accept TeX and LaTeX.                editorial office. Failure to do so will result in delays to the publica-
                                                                        tion of your paper. A copy of the License to Publish form can be
File sizes must be as small as possible so that they can be             found under “Instructions & Forms” on the online submission page:
downloaded quickly. Images should not exceed 640 x 480 pixels           http://mc.manuscriptcentral.com/ki
but we would recommend 480 x 360 pixels as the maximum frame
size for movies. We would also recommend a frame rate of 15             The International Society of Nephrology does not require au-
frames per second. If applicable to the presentation of the supple-     thors of original research papers to assign copyright of their pub-

                                                       REVISED March 15, 2011                                                                 5
GUIDE TO AUTHORS

lished contributions. Authors grant the International Society of         PUBLIC ACCESS POLICY
Nephrology an exclusive license to publish, in return for which          Nature Publishing Group and Kidney International support the pub-
they can re-use their papers in their future printed work. Authors       lic access policy but are not able to deposit accepted manuscripts
are encouraged to submit their version of the accepted, peer-            for the authors at this time. Authors are allowed (without requesting
reviewed manuscript to their funding body's archive for public re-       permission) to deposit the accepted (i.e., untypeset, uncopyedited)
lease six months after publication. In addition, authors are encour-     version of their accepted manuscripts in PubMed Central. You can
aged to archive their version of the manuscript in their institution's   deposit your manuscript here: http://www.nihms.nih.gov.
repositories (as well as on their personal web sites), also six
months after the original publication. Authors should cite the publi-    PROOFS
cation reference and doi number on any deposited version, and            An e-mail will be sent to the corresponding author with a URL link
provide a link from it to the published article on the NPG website.      from where proofs can be collected. Proofs must be returned by fax
This policy complements the policies of the US National Institutes       within 48 hours of receipt. Failure to do so may result in a delay to
of Health, the Wellcome Trust and other research funding bodies          publication. Extensive corrections cannot be made at this stage.
around the world. NPG recognizes the efforts of funding bodies to
increase access to the research they fund, and strongly encour-
ages authors to participate in such efforts.                             BUSINESS MATTERS
More information is available online at the following link:              For contact information regarding business correspondence and
http://www.nature.com/authors/editorial_policies/license.html            inquiries such as advertising, subscriptions, permissions, papers in
                                                                         production or publishing a supplement, please visit our publisher’s
ADVANCE ONLINE PUBLICATION                                               contacts page at http://www.nature.com/ki/contact_npg.html.
All original articles and reviews are published ahead of print on
Advance Online Publication. This will be the final version of the        Alternatively, you can write to: Kidney International, Academic
manuscript and will subsequently appear, unchanged, in print.            Journals Division, Nature Publishing Group, 75 Varick Street, 9th
                                                                         Floor, New York, NY 10013, USA.




Appendix
SAVING FILES WITH MICROSOFT OFFICE 2007
MS Office 2007 saves files in an XML format by default (file extensions .docx, .pptx and .xlsx). Files saved in this format cannot currently be
accepted for publication.

Save Word documents using the file extension .doc
  •    Select the Office Button in the upper left corner of the Word 2007 window and choose “Save As”
  •    Select “Word 97-2003 Document”
  •    Enter a file name and select “Save”
These instructions also apply to the 2007 version of Excel and PowerPoint.

Equations in Word must be created using Equation Editor 3.0
Equations created using the new equation editor in Word 2007 and saved as a “Word 97-2003 Document” (.doc) are converted to graphics
and can no longer be edited. To insert or change an equation with the previous equation editor:
  •    Select “Object” on the “Text” sections of the “Insert” tab
  •    In the drop-down menu, select “Equation Editor 3.0”
Do not use the “Equation” button in the “Symbols” section of the “Insert” tab.




                                                        REVISED March 15, 2011                                                               6

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Author guide updated 15_mar_11_final

  • 1. GUIDE TO AUTHORS Table of Contents New Membership Category introduced for Members in About the Journal p1 Training Preparation of Manuscripts p2 Trainees in nephrology up to the age of 37 years are now Content Types p2 encouraged to apply to become ISN Members in Training at a Format of Manuscripts p3 greatly reduced annual membership rate of US$ 70 (all benefits Figures and Tables p4 included). Eligible individuals must submit a copy of a valid Supplementary Information p5 form of identification stating their date of birth as well as a proof Submission and Publication p5 of their current training status to the ISN Global Headquarters Appendix p6 together with their completed application. http://www.nature.com/isn/society/membership/isn_20048.html About the Journal context. These will form a research tool for clinical and ba- sic investigators. PUBLICATION CHARGES (Do not apply to invited authors) • Editorials that highlight important issues in international ne- phrology Page charges • Nephrology sans Frontieres - occasional short articles that Manuscripts accepted for publication in Kidney International will discuss matters of local interest to nephrologists around the incur page charges to cover, in part, the cost of publication. A world, but which we feel need to be known by nephrologists charge of $74 will be issued for each journal page. world-wide Color charges • Short reviews on hot topics and in depth reviews about ma- All figures that are submitted as color artwork must be published in jor issues in renal research. color. The authors will be expected to contribute towards the cost • Controversial discussions on renal therapeutics or diagno- of color art .The cost for reproducing color artwork in print is $530 sis written by two opposing authorities per page. Color figures will be set close to the citation and in the • State of the Art teaching materials including clinico- best possible position. Figure re-ordering cannot be undertaken at pathological conferences where eminent clinicians discuss proof stage to reduce the number of pages featuring color artwork. difficult or interesting cases illustrated by multiple pathol- ogy, imaging studies and charts Upon acceptance authors must fill in the artwork form available at • Images in Nephrology which are presentations of interest- http://mc.manuscriptcentral.com/societyimages/ki/KI%20Artwork% ing images in renal pathology, radiology chosen for their il- 20Form.pdf lustrative nature or simply for their esthetic qualities. • Issues of importance to the international renal community Offprints including the politics of funding; of organ transplantation, of Offprints may be ordered using the order form available for down- adequacy of dialysis, of world-wide affordability of end load with the proofs. stage renal care and many other topical issues. • Journal Club are synopses that bring you the latest re- search highlights from across a wide spectrum of journals IMPACT FACTOR in fields relevant to renal research 2009 Impact Factor 6.193* • Book Reviews 3/63 Urology and Nephrology *2009 Journal Citation Reports (Thomson Reuters, 2010) ABSTRACTED/ INDEXED IN • Index Medicus/Medline ISSN • Science Citation Index ISSN: 0085-2538 • Current Contents/Life Sciences EISSN: 1523-1755 • Current Contents/Clinical Medicine • SciSearch • BIOSIS FREQUENCY • Chemical Abstracts Printed twice a month. Advance online Publication once a week. • EMBASE/Excerpta Medica • Reference Update • CABS SCOPE • Biological Abstracts Kidney International aims to inform the renal researcher and the • Global Health practicing nephrologist on all aspects of renal research, including: • MDX Health Digest • The latest clinical studies on emerging developments in re- • EBSCO nal medicine. • Adonis • The highest level of original research studies in clinical and • PASCAL basic renal research. • In each issue, some articles will be highlighted by commen- taries that aim to put these studies in the appropriate REVISED March 15, 2011
  • 2. GUIDE TO AUTHORS empt. A list of acceptable registries is available on the ICMJE web- Preparation of manuscripts site (http://www.icmje.org). Each manuscript will be checked upon submission to determine whether the study has been appropriately registered. All studies which began enrolling patients after July 1, Manuscripts that do not adhere to the following instructions 2005 must have been registered before patient enrollment. Any trial will be returned to the corresponding author for technical which was still seeing patients on September 13, 2005, should revision before undergoing peer review. have been registered before September 13, 2005. If the trial was complete before September 13, 2005, the study should be regis- tered before submission. Content Types Reporting of randomized controlled trials should follow the guide- lines of The CONSORT Statement The types of manuscripts accepted by KI are: (1) Review, (2) Mini- (http://www.consortstatement.org). review, (3) Original Article, (4) Commentary, (5) Technical Note, (6) Letter to the Editor (7), Editorial (8), Nephrology Image, (9) Make Your Diagnosis, (10) Book Review, (11) ISN Forefronts in (4) Commentary [only by invitation of Editors] Nephrology, ISN Nexus, Meeting Report. Word limit: 1500 words (8,400 characters) maximum including spaces and abstract but excluding references Title: 115 characters maximum including spaces Abstract: 75 words (420 characters) maximum (1) Review References: 10 maximum including the article discussed Word limit: 5,000 words (28,000 characters) maximum including Figures/tables: 1 figure required (will be redrawn) spaces and abstract but excluding references, tables and figures. Commentaries discuss a paper published in a specific issue and Abstract: 250 words (1500 characters) maximum including spaces should set the problems addressed by the paper in the wider con- References: no maximum text of the field. Authors will not be charges for color images. Figures/tables: 3 images or figures required Disclosure statement required (see page 3 for details) (5) Technical Note Reviews are comprehensive analyses of specific topics in nephrol- Word limit: 1500 words (8,400 characters) maximum including ogy that are usually solicited by the Editors. Proposals for reviews abstract but excluding references, tables and figures. may be submitted; however, in this case authors should only send Abstract: 250 words (1500 characters) maximum including spaces an outline of the proposed paper for initial consideration. Both References: 20 maximum solicited and unsolicited review articles will undergo peer review Disclosure statement required (see page 3 for details) prior to acceptance. Kidney International will cover charges for Examples of appropriate subject matter include descriptions of new color images for articles invited by the Editors, and for images in laboratory or clinical methods, new apparatus, or critical modifica- which color was added by the journal. tions of established techniques. Organization of Technical Notes should be the same as for regular manuscripts except that section (2) Minireview headings should be omitted. Word limit: 3000 words (16,800 characters) maximum including spaces and abstract but excluding references, tables and figures. (6) Letter to the Editor Abstract: 250 words (1500 characters) maximum including spaces Word limit: 250 words (1500 characters) maximum including References: 20 maximum spaces Figures/tables: 2 images or figures required Abstract: no abstract required for this manuscript type Disclosure statement required (see page 3 for details) References: 4 maximum Minireviews of topical and highly focused subjects are usually Figures/ tables: Up to 1 solicited by the Editors. Proposals for minireviews may be submit- Letters to the Editor will be considered for publication, subject to ted; however, in this case authors should only send an outline of editing. Letters must contain information critical to a certain area or the proposed paper for initial consideration. Both solicited and must be confirmatory of data recently published in Kidney Interna- unsolicited review articles will undergo peer review prior to accep- tional. A Letter must reference the original source, and a Response tance. Kidney International will cover charges for color images for to a Letter must reference the Letter in the first few paragraphs, as articles invited by the Editors, and for images in which color was well as the original source. Letters can use an arbitrary title, but a added by the journal. Response must cite the title of the Letter: e.g. Response to [title of Letter]. All Letters must contain a title page including title, all au- (3) Original Article thors’ names and affiliations, and corresponding author contact Sub-categories: Basic Research, Clinical Research, Clinical information. Trials Word limit: 4000 words (22,400 characters) maximum including (7) Editorial [only by invitation of Editors] spaces and abstract but excluding references, tables and figures. Word Limit: 1600 words (8,960 characters) maximum including Abstract: 250 words (1500 characters) maximum including spaces. spaces Results: Include headings about what is being tested in each indi- Abstract: no abstract required for this manuscript type vidual experiment. References: 5 maximum References: no limit Proposals for Editorials may be submitted; authors should only Figures/ tables: no limit. However, additional figures and tables send an outline of the proposed paper for initial consideration. may be considered as supplements for Web-only publication. Disclosure statement required (see page 3 for details) (8) Nephrology Image Full-length reports of current research in either basic or clinical Word limit: Title: 70 characters including spaces; text: 300 words science. (1700 characters) including spaces Figures: 2 single panel figures maximum. No multi-part figures Special Notice Regarding Clinical Trials: allowed. Kidney International encourages the submission of manuscripts References: none reporting results of clinical trials and must be submitted under a Abstract: no abstract required for this manuscript type separate category under Original Articles - Clinical Trials. It is im- Illustrative images that are unique or highly illustrative of specific portant to follow the recommendations of the International Commit- occurrences in Nephrology such as renal pathology, radiology, tee of Medical Journal Editors (ICMJE), which requires that “any specific skin lesions, etc. They should be accompanied by a brief research project that prospectively assigns human subjects to one-paragraph description of relevant clinical information. Article intervention and comparison groups to study the cause-and-effect must fit onto one page. You will be asked to cut text or part of your relationship between a medical intervention and a health outcome” figure in the proof if article is longer than one page. must be registered before the start of patient enrollment. Trials in which the primary goal is to determine pharmacokinetics are ex- REVISED March 15, 2011 2
  • 3. GUIDE TO AUTHORS (9) Make Your Diagnosis Title Page Word limit: Title: 70 characters; The Case (page 1): 245 words Abstract (1400 characters); The Diagnosis (page 2): 405 words (2300 char- Introduction acters). Word limits include spaces but exclude references, tables Results and figures. Discussion Abstract: no abstract required for this manuscript type Methods References: 3 maximum Disclosure Figures/tables: 1 single panel figures maximum per page References This column provides readers with an opportunity to make clinical Acknowledgements diagnoses based on an image accompanied by the history and physical exam, all of which will be on the first page. The second page will include the answers, a brief discussion and any other Abbreviations relevant follow up images and laboratory data. Abbreviations should be defined at the first mention in the text and in each table and figure. For a list of standard abbreviations, please (10) Book Review consult the Council of Biology Editors Style Guide (available from Word limit: 500-1000 words including spaces, excluding references the Council of Science Editors, 9650 Rockville Pike, Bethesda, MD Abstract: no abstract required for this manuscript type 20814) or other standard sources. Write out the full term for each References: 3 maximum abbreviation at its first use unless it is a standard unit of measure. Book Reviews alert readers to work that is potentially important to Refrain from overuse of abbreviations. the field of nephrology, and puts it in context with the nephrology literature. Book Reviews should follow this outline: (a) exact title of Disclosure book, full name(s) of author(s), publisher’s name, publication date, For original articles and reviews only, the submitting author must number of pages and price, (b) summary of the content (general include a disclosure statement in the body of the manuscript. The discussion of what the book covers and its major topics; NOT a statement will describe all of the authors’ relationships with compa- chapter by chapter summary), (c) discussion of author(s) (for ex- nies that may have a financial interest in the information contained ample, background, experience, why they are qualified to write the in the manuscript. This information should be provided under the book and whether they present a certain view), (d) strong points of heading titled ‘Disclosure,’ which should appear after the ‘Methods’ the book, (e) weak points of the book, (f) identification of the audi- section and before the ‘References’ section. The absence of any ence of this book and the background needed for the reader to interest to disclose must also be stated. In addition, any financial understand its contents, (g) discussion of why one should or interests must be detailed in the Financial Disclosure form, which should not buy the book, and if yes, for what purpose (as a text, a will be provided to the corresponding author upon acceptance for reference, etc.), (h) comparison to other books in the field, and (i) if distribution to each author. possible, a “quotable quote” or annotation regarding the book. References (11) ISN Forefronts in Nephrology, ISN Nexus, Meeting Report References should be listed in order of appearance (Vancouver [only by invitation of Editors] style). In the text, number references in order of appearance using Word limit: To be determined in consultation with Editors Arabic numerals (e.g. 1, 2, 3) in parentheses for citations. The Abstract: 150 words (1500 characters) maximum including spaces, reference list (starting on a separate page) should contain the ref- excluding references and figures. erences in the order in which they are cited in the text. Only pub- References: no maximum lished works (as well as manuscripts already accepted for Figures/tables: at least 1 image or figure publication) which are referred to in the text should be listed in the Disclosure statement required (see page 3 for details) reference list. The reference list must not contain any abstract These authoritative proceedings of specific topics in nephrology citations, unpublished observations, personal communications, etc. are usually solicited by the Editors. Proposals may be submitted; Kindly cite such sources solely within the text (in parentheses), not authors should only send an outline of the proposed paper for in the reference list. Do not list more than three authors per refer- initial consideration. Both solicited and unsolicited articles will un- ence. Should there be four or more, please include only the first dergo peer review prior to acceptance. Kidney International will three followed by ‘‘et al.’’ cover charges for color images in articles invited by the Editors. The following examples demonstrate correct reference style: Format of Manuscripts Journal articles: Fan SL-S, Almond MK, Ball E, et al. Pamidronate therapy as pre- GENERAL FORMAT vention of bone loss following renal transplantation. Kidney Int Manuscripts must be typed in English and double-spaced. All text 2000; 57: 684–690. including legends, footnotes, tables and references are to be on one side of the page only. All manuscript pages must be num- Supplement articles: bered. Fogo AB. Glomerular hypertension abnormal glomerular growth, and progression of renal diseases. Kidney Int 2000; 57 (Suppl 75): Title page S15–S21. This should include (a) the complete manuscript title; (b) all au- thors’ full names (listed as first name, middle initial, last name), Books: highest academic degrees, and affiliations; (c) the name and ad- Lameire N, Mehta RL (eds.). Complications of Dialysis. Marcel dress for correspondence, fax number, telephone number, and e- Dekker, Inc.: New York, 2000. mail address; and (d) the sources of support that require acknowl- edgment. A running headline of no more than 50 characters (in- Articles in books: cluding spaces) should be supplied. Weidner N, Buckalew VM Jr. Sickle cell anemia, sickle cell trait, and polycythemic states, in Renal Pathology (vol 2), eds. Tisher Abstract and Keywords CC, Brenner BM. JB Lippincott Company: Philadelphia, 1989, pp The abstract should be no longer than 1500 characters including 1417–1436. spaces, stating the main problem, methods, results, and conclu- sions. There should be no subheadings in the abstract. It must be factual and comprehensive. The use of abbreviations and acro- ORIGINALITY nyms should be limited and general statements (e.g. ‘‘the signifi- A submitted manuscript must be an original contribution not previ- cance of the results is discussed’’) should be avoided. ously published (except as an abstract or preliminary report), must not be under consideration for publication elsewhere, and, if ac- Text cepted, must not be published elsewhere in a similar form, in any The manuscript should be organized under the following nine language, without the consent of the ISN. Each person listed as an headings: author is expected to have participated in the study to a significant REVISED March 15, 2011 3
  • 4. GUIDE TO AUTHORS extent and agrees with submission of the paper for publication. Journal style Although the editors and referees make every effort to ensure the As the electronic submission will provide the basic material for validity of published manuscripts, the final responsibility rests with typesetting, it is important that papers are prepared in the general the authors, not with Kidney International, its editors, the Interna- editorial style of the journal. tional Society of Nephrology or Nature Publishing Group. 1. For information on labeling of figures, see the artwork guidelines: http://www.nature.com/aj/artworkguidelines.pdf INFORMED CONSENT AND ETHICS 2. Do not make rules thinner than 1 pt (0.36mm) When reporting experiments on human subjects, indicate whether 3. Use a coarse hatching pattern rather than shading for tints the procedures were in accordance with the ethical standards of in graphs the responsible committee on human experimentation (institutional 4. Color should be distinct when used as an identifying tool or regional) or with the Helsinki Declaration of 1975 (and as re- 5. Use SI units throughout vised in 1983). Include any Institutional Review Board or Animal 6. Spaces, not commas, should be used to separate thou- Care and Use Committee protocol numbers as warranted by ex- sands perimental design. 7. Abbreviations should be preceded by the words for which they stand in the first instance of use in the text. Overuse of abbreviations in the text is discouraged GUIDELINES FOR STUDIES OF DNA POLYMORPHISMS 8. No abbreviations should be used in the title or the For case-control studies investigating associations between DNA abstract sequence polymorphisms and renal phenotypes the following re- 9. The abstract should be written as a single paragraph; do view criteria will be considered in prioritizing manuscripts for publi- not include headings cation: 10. Text should be double spaced with a wide margin 11. At the first mention of a manufacturer, the town (state if 1. Adequate sample size and explicit power calculation are re- USA) and country should be provided quired for all submitted manuscripts. Negative studies have to be adequately powered in order to be considered for publication. 2. Appropriate correction of p-values for multiple comparisons is FILE FORMATS also required. In many cases this will involve calculation of empiric Manuscripts p-values by permutation. Use Microsoft Word for the text of your article. Files in MS Office 2007 format cannot be accepted for publication. For instructions on 3. Typing multiple markers within a locus of interest is preferred how to save MS Office 2007 files in a format acceptable for publi- over studies that examine a single polymorphism. Defining risk cation, please see the Appendix. haplotypes and performing haplotypic association tests is encour- aged. Figures, Images and Tables Figures and images should be labeled sequentially, numbered and 4. Assessment and correction for possible population stratification cited in the text. Figures should be referred to specifically in the text are strongly encouraged, unless the analysis involves a method of the paper but should not be embedded within the text. Each that is robust to stratification effects (eg. transmission- table should be double-spaced on a separate sheet and numbered disequilibrium testing). consecutively in the order of first citation in the text. Make sure that each table is cited in the text. Tables must be submitted as Micro- 5. Replication of the association in an independent cohort is re- soft Word documents. Do not use internal horizontal and vertical quired for new association findings. lines. The use of three-dimensional histograms is strongly discour- aged when the addition of the third dimension gives no extra infor- 6. Priority will be given to studies that demonstrate a specific effect mation. If a table or figure has been published before, the authors of the associated polymorphism on the expression or function of must obtain written permission to reproduce the material in both the relevant genes. A convincing biological validation will be con- print and electronic formats from the copyright owner and submit sidered in lieu of the replication requirement. the permission with the manuscript. This rule applies for quotes, illustrations and other materials taken from previously published MICROARRAY DATA works not in the public domain. The original source should be cited Authors submitting manuscripts containing microarray data must in the figure caption or table footnote. submit the data to the Gene Expression Omnibus (http://www.ncbi.nlm.nih.gov/geo/) or ArrayExpress Legends and Titles (http://www.ebi.ac.uk/arrayexpress/) databases, and provide the Legends must be submitted for all figures and images, and titles for accession number(s) upon submission to the journal. The data all tables. They should be brief and specific, double spaced, and must be MIAME-compliant, with all variables completed. placed on a separate sheet titled ‘Titles and legends’ after the Ref- erence section. Use scale markers in the image for electron micro- graphs and indicate the type of stain used. Place explanatory STYLE matter of tables in the footnotes rather than in the titles. The American Medical Association Manual of Style (9th edition), Stedman’s Medical Dictionary (27th edition) and Merriam Web- ARTWORK GUIDELINES ster’s Collegiate Dictionary (10th edition) should be used as stan- Detailed guidelines for submitting artwork can be found by dard references. Refer to drugs and therapeutic agents by their downloading the guidelines PDF: accepted generic or chemical name, and do not abbreviate them (a http://www.nature.com/aj/artworkguidelines.pdf. Using the guide- proprietary name may be given only with the first use of the ge- lines, please submit production quality artwork with your submis- neric name). Code numbers should be used only when a generic sion. At submission, all figures must be high enough quality (no name is not yet available (the chemical name and a figure giving less than 300 dpi) to be assessed in the peer review process. We the chemical structure of the drug are required). Copyright or trade prefer artwork to be submitted in eps, .jpg, .ppt, or .tif format. pdf or names of drugs should be capitalized and placed in parentheses Corel Draw format is discouraged. If you have not followed the after the name of the drug. Names and locations (city and state in artwork guidelines, we will require artwork to be resubmitted if your USA; city and country outside USA) of manufacturers of drugs, paper is accepted for publication. supplies, or equipment cited in a manuscript are required to com- ply with trademark law and should be provided in parentheses. Minimum Resolutions: Halftone images 300 dpi (dots per inch) Quantitative data may be reported in the units used in the original Color images 300 dpi saved as CMYK measurement, but SI units are preferred, including those applica- Images containing text 400 dpi ble to body weight, mass (weight) and temperature. Line art 1000 dpi REVISED March 15, 2011 4
  • 5. GUIDE TO AUTHORS Sizes: mentary information, use a 256-color palette. Please consider the Figure Width – single image use of lower specification for all of these points if the supplemen- 86mm (Should be able to fit into a single column of the tary information can still be represented clearly. Our recommended printed journal) maximum data rate is 150 KB/s. Figure Width – multi-part image The number of files should be limited to eight, and the total file size 178mm (Should be able to fit into a double column of the should not exceed 8 MB. Individual files should not exceed 1 MB. printed journal) Please seek advice from the editorial office before sending files larger than our maximum size to avoid delays in publication. Text Size 8 point (Should be readable after reduction – avoid large type Further questions about the submission or preparation of supple- or thick lines) Line Width Between 0.5 and 1 point mentary information should be directed to the editorial office. Color Artwork Charges Open Access Artwork provided in color upon submission must be printed in Upon submission of an original research paper, authors can indi- color, and the author must agree to pay for the cost of printing said cate within the manuscript tracking system whether they wish to artwork in color. The cost to produce color artwork is $530 per pay an article processing charge to allow their article to be pub- page. Color figures will be set close to the citation and in the best lished open access. The article processing charge is possible position. Figure re-ordering cannot be undertaken at proof £2,000/$3,000/€2,400 (plus VAT where applicable) and stage to reduce the number of pages featuring color artwork. can be paid via credit card or by requesting an invoice be raised. By paying this article processing charge, authors are permitted to post the final, published pdf of their article on a website, institu- Supplementary Information tional repository or other free public server immediately on publica- tion. Upon acceptance, authors must fill out and send back a Supplementary information is peer-reviewed material directly rele- payment form. This is mandatory and failure to send in the pay- vant to the conclusion of an article that cannot be included in the ment form along with the Licence to Publish form will result in the printed version owing to space or format constraints. It is posted on article being published as a standard paper behind access control. the journal’s web site and linked to the article when the article is (Note: US Government employees must use this license to publish published and may consist of data files, graphics, movies or exten- form.) sive tables. The printed article must be complete and self- explanatory without the supplementary information. Supplementary The licence to publish form has been amended to offer authors the information enhances a reader’s understanding of the paper, but is choice of which licence to use on their paper and these choices are not essential to that understanding. Supplementary information described below: must be supplied to the editorial office in its final form for peer review. On acceptance, the final version of the peer-reviewed sup- The first is the Creative Commons Attribution-Noncommercial-No plementary information should be submitted with the accepted Derivative Works 3.0 Unported Licence and allows readers to paper. To ensure that the contents of the supplementary informa- download the article and share it with others as long as they men- tion files can be viewed by the editor(s), referees and readers, tion the author and link back to the original article. 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Authors should: include a text sion page: http://mc.manuscriptcentral.com/ki summary (no more than 50 words) to describe the contents of All text should be submitted in Microsoft Word (.doc) and fig- each file; identify the types of files (file formats) submitted and ures as .tif or .jpg files include the text ‘Supplementary information is available at Kidney Figures appearing in the online version of manuscripts will be pub- International’s website’ at the end of the article and before the lished in 72 dpi as is standard for all .pdf files on the internet. All references. figures published in print are at least 300 dpi. Accepted file formats Quick Time files (.mov), graphical image files (.gif), HTML files (.html), MPEG movie files (.mpg), JPEG image files (.jpg), sound LICENSE TO PUBLISH files (.wav), plain ASCII text (.txt), MS Word documents (.doc), The corresponding author must complete and sign the License to Postscript files (.ps), MS Excel spreadsheet documents (.xls) and Publish form upon acceptance of the manuscript and return it to the PowerPoint files (.ppt). We cannot accept TeX and LaTeX. editorial office. Failure to do so will result in delays to the publica- tion of your paper. A copy of the License to Publish form can be File sizes must be as small as possible so that they can be found under “Instructions & Forms” on the online submission page: downloaded quickly. Images should not exceed 640 x 480 pixels http://mc.manuscriptcentral.com/ki but we would recommend 480 x 360 pixels as the maximum frame size for movies. We would also recommend a frame rate of 15 The International Society of Nephrology does not require au- frames per second. If applicable to the presentation of the supple- thors of original research papers to assign copyright of their pub- REVISED March 15, 2011 5
  • 6. GUIDE TO AUTHORS lished contributions. Authors grant the International Society of PUBLIC ACCESS POLICY Nephrology an exclusive license to publish, in return for which Nature Publishing Group and Kidney International support the pub- they can re-use their papers in their future printed work. Authors lic access policy but are not able to deposit accepted manuscripts are encouraged to submit their version of the accepted, peer- for the authors at this time. Authors are allowed (without requesting reviewed manuscript to their funding body's archive for public re- permission) to deposit the accepted (i.e., untypeset, uncopyedited) lease six months after publication. In addition, authors are encour- version of their accepted manuscripts in PubMed Central. You can aged to archive their version of the manuscript in their institution's deposit your manuscript here: http://www.nihms.nih.gov. repositories (as well as on their personal web sites), also six months after the original publication. Authors should cite the publi- PROOFS cation reference and doi number on any deposited version, and An e-mail will be sent to the corresponding author with a URL link provide a link from it to the published article on the NPG website. from where proofs can be collected. Proofs must be returned by fax This policy complements the policies of the US National Institutes within 48 hours of receipt. Failure to do so may result in a delay to of Health, the Wellcome Trust and other research funding bodies publication. Extensive corrections cannot be made at this stage. around the world. NPG recognizes the efforts of funding bodies to increase access to the research they fund, and strongly encour- ages authors to participate in such efforts. BUSINESS MATTERS More information is available online at the following link: For contact information regarding business correspondence and http://www.nature.com/authors/editorial_policies/license.html inquiries such as advertising, subscriptions, permissions, papers in production or publishing a supplement, please visit our publisher’s ADVANCE ONLINE PUBLICATION contacts page at http://www.nature.com/ki/contact_npg.html. All original articles and reviews are published ahead of print on Advance Online Publication. This will be the final version of the Alternatively, you can write to: Kidney International, Academic manuscript and will subsequently appear, unchanged, in print. Journals Division, Nature Publishing Group, 75 Varick Street, 9th Floor, New York, NY 10013, USA. Appendix SAVING FILES WITH MICROSOFT OFFICE 2007 MS Office 2007 saves files in an XML format by default (file extensions .docx, .pptx and .xlsx). Files saved in this format cannot currently be accepted for publication. Save Word documents using the file extension .doc • Select the Office Button in the upper left corner of the Word 2007 window and choose “Save As” • Select “Word 97-2003 Document” • Enter a file name and select “Save” These instructions also apply to the 2007 version of Excel and PowerPoint. Equations in Word must be created using Equation Editor 3.0 Equations created using the new equation editor in Word 2007 and saved as a “Word 97-2003 Document” (.doc) are converted to graphics and can no longer be edited. To insert or change an equation with the previous equation editor: • Select “Object” on the “Text” sections of the “Insert” tab • In the drop-down menu, select “Equation Editor 3.0” Do not use the “Equation” button in the “Symbols” section of the “Insert” tab. REVISED March 15, 2011 6