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Nanotechnologies safety and health
        initiatives: Using NIOSH Resources

 The 234th ACS National Meeting, Boston, MA
                                August 21, 2007
                  Scott M. Hollenbeck, CIH
          Center for Nanophase Materials Sciences
               Oak Ridge National Laboratory



OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                                    1
Resources available to the Nanotech R&D
        Community, a customer’s perspective

•  What is NIOSH?
•  NIOSH Approaches to Safe Nanotechnology
•  NIOSH Website
•  R&D into S&H for Nanomaterials (defining
   hazards and controls)
•  Library of reference materials
•  Training and education
•  Control Banding information
OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                                2
About NIOSH
   The National Institute for Occupational
     Safety and Health is:
   the U.S. Federal agency responsible for
   conducting research and
             making recommendations
   for the prevention of work-related
     injury and illness.


OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                             3
Approaches to Safe Nanotechnology
    A key resource used in developing the CNMS and
                 DOE Control guidance
   NIOSH created the Approaches to Safe
     Nanotechnology guidance document to:
    raise awareness of potential safety and
     health concerns from exposure to
     nanomaterials, and to
   address current and future research needs
     essential to understanding the potential risks
     that nanotechnology may have to workers.
OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                                     4
Information Resources on the NIOSH
                 Nanotechnology Topic Page
•  Approaches to Safe Nanotechnology: A Dialogue with NIOSH
•  The Nanoparticle Information Library
    –  Particle-specific information
        •  Physical and chemical form
        •  Origin
        •  Available toxicity data
    –  A contributor database to facilitate networking
    –  Direct search links to:
        •  NIOSH Pocket Guide to Chemical Hazards
        •  Registry of Toxic Effects of Chemical Substances (RTECS)
        •  Wilson Center research database
        •  ICON EHS Bibliography

    –  Options for including control information and lessons learned
 OAK RIDGE NATIONAL LABORATORY
 U. S. DEPARTMENT OF ENERGY
                                              www.cdc.gov/niosh/topics/nanotech
                                                                             5
NIOSH: Top Five Measurement
                        Research Needs
 (NNI Nanotechnology Environmental and Health Implications – 2007)

1.       Develop methods for detecting nanomaterials in
      biological matrices, the environment, and workplace
2.      Understand the effect of modifications
      on the properties of nanomaterials
3.       Develop methods for standardizing assessment
      of particle size and size distribution
4.      Develop Standard Reference Materials for
      physicochemical characterization of nanomaterials
5.      Develop methods to characterize a nanomaterial's
      spatio-chemical composition
 OAK RIDGE NATIONAL LABORATORY
 U. S. DEPARTMENT OF ENERGY
                                                                     6
The following viewgraphs are from
             NIOSH activities and laboratories




OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                                 7
Ideally, this will enable a comprehensive assessment
           of all task-specific exposure pathways




OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                Adapted from NIOSH: Day et al. 2007   8
OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                9
OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                10
OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                11
OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                12
OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                13
OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                14
VOLUNTEER PARTNERS NEEDED FOR THE
    NIOSH NANOTECHNOLOGY FIELD RESEARCH EFFORT
•  The NIOSH field research team is available to visit and assess processes
   involving research, production, and use of nanomaterials.

•  The team will characterize materials, processes, potential worker exposures,
   work practices, and control procedures.

•  Information and recommendations will be shared with the volunteer partner.

•  Information will be used by NIOSH to update the guidance that appears in
   Approaches to Safe Nanotechnology on the our NanotechnologyTopic Page.
                              There is no cost to participate!!!
  If your organization is interested in volunteering to participate, please contact
Charles L. Geraci, PhD, CIH            NIOSH               Mark M. Methner, PhD, CIH
                                Mark D. Hoover, PhD, CHP, CIH
E-mail: CGeraci@cdc.gov         E-mail: MHoover1@cdc.gov        E-mail: MMethner@cdc.gov
Phone: 513-533-8339             Phone: 304-285-6374             Phone: 513-841-4325
FAX: 513-533-8230               FAX: 304-286-6321               FAX: 513-458-7147
 OAK RIDGE NATIONAL LABORATORY
 U. S. DEPARTMENT OF ENERGY
                                                                                       15
Questions?

                 For more information on NIOSH and Nanotech:

                 Mark D. Hoover, PhD, CHP, CIH
                 NIOSH Nanotechnology Research Center
                 and Division of Respiratory Disease Studies
                 National Institute for Occupational Safety and Health
                 Centers for Disease Control and Prevention
                 1095 Willowdale Road
                 Morgantown, West Virginia 26505-2888
                 Phone: 304-285-6374
                 Email: mark.hoover@cdc.hhs.gov

OAK RIDGE NATIONAL LABORATORY
U. S. DEPARTMENT OF ENERGY
                                                                         16

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Nano At Niosh

  • 1. Nanotechnologies safety and health initiatives: Using NIOSH Resources The 234th ACS National Meeting, Boston, MA August 21, 2007 Scott M. Hollenbeck, CIH Center for Nanophase Materials Sciences Oak Ridge National Laboratory OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 1
  • 2. Resources available to the Nanotech R&D Community, a customer’s perspective •  What is NIOSH? •  NIOSH Approaches to Safe Nanotechnology •  NIOSH Website •  R&D into S&H for Nanomaterials (defining hazards and controls) •  Library of reference materials •  Training and education •  Control Banding information OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 2
  • 3. About NIOSH The National Institute for Occupational Safety and Health is: the U.S. Federal agency responsible for conducting research and making recommendations for the prevention of work-related injury and illness. OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 3
  • 4. Approaches to Safe Nanotechnology A key resource used in developing the CNMS and DOE Control guidance NIOSH created the Approaches to Safe Nanotechnology guidance document to: raise awareness of potential safety and health concerns from exposure to nanomaterials, and to address current and future research needs essential to understanding the potential risks that nanotechnology may have to workers. OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 4
  • 5. Information Resources on the NIOSH Nanotechnology Topic Page •  Approaches to Safe Nanotechnology: A Dialogue with NIOSH •  The Nanoparticle Information Library –  Particle-specific information •  Physical and chemical form •  Origin •  Available toxicity data –  A contributor database to facilitate networking –  Direct search links to: •  NIOSH Pocket Guide to Chemical Hazards •  Registry of Toxic Effects of Chemical Substances (RTECS) •  Wilson Center research database •  ICON EHS Bibliography –  Options for including control information and lessons learned OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY www.cdc.gov/niosh/topics/nanotech 5
  • 6. NIOSH: Top Five Measurement Research Needs (NNI Nanotechnology Environmental and Health Implications – 2007) 1.  Develop methods for detecting nanomaterials in biological matrices, the environment, and workplace 2.  Understand the effect of modifications on the properties of nanomaterials 3.  Develop methods for standardizing assessment of particle size and size distribution 4.  Develop Standard Reference Materials for physicochemical characterization of nanomaterials 5.  Develop methods to characterize a nanomaterial's spatio-chemical composition OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 6
  • 7. The following viewgraphs are from NIOSH activities and laboratories OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 7
  • 8. Ideally, this will enable a comprehensive assessment of all task-specific exposure pathways OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY Adapted from NIOSH: Day et al. 2007 8
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  • 10. OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 10
  • 11. OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 11
  • 12. OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 12
  • 13. OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 13
  • 14. OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 14
  • 15. VOLUNTEER PARTNERS NEEDED FOR THE NIOSH NANOTECHNOLOGY FIELD RESEARCH EFFORT •  The NIOSH field research team is available to visit and assess processes involving research, production, and use of nanomaterials. •  The team will characterize materials, processes, potential worker exposures, work practices, and control procedures. •  Information and recommendations will be shared with the volunteer partner. •  Information will be used by NIOSH to update the guidance that appears in Approaches to Safe Nanotechnology on the our NanotechnologyTopic Page. There is no cost to participate!!! If your organization is interested in volunteering to participate, please contact Charles L. Geraci, PhD, CIH NIOSH Mark M. Methner, PhD, CIH Mark D. Hoover, PhD, CHP, CIH E-mail: CGeraci@cdc.gov E-mail: MHoover1@cdc.gov E-mail: MMethner@cdc.gov Phone: 513-533-8339 Phone: 304-285-6374 Phone: 513-841-4325 FAX: 513-533-8230 FAX: 304-286-6321 FAX: 513-458-7147 OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 15
  • 16. Questions? For more information on NIOSH and Nanotech: Mark D. Hoover, PhD, CHP, CIH NIOSH Nanotechnology Research Center and Division of Respiratory Disease Studies National Institute for Occupational Safety and Health Centers for Disease Control and Prevention 1095 Willowdale Road Morgantown, West Virginia 26505-2888 Phone: 304-285-6374 Email: mark.hoover@cdc.hhs.gov OAK RIDGE NATIONAL LABORATORY U. S. DEPARTMENT OF ENERGY 16