1. Essential facts in Geriatric
Medicine
The Role of Geriatrician
Dr Asso Fariadoon Ali Amin (MRCP)
GIM and Care of Elderly specialist
2. Essential Facts in Geriatric Medicine
Main Objectives
• Statistics on Elderly
• Main features of Geriatric Medicine
• Facts about the life of Elderly in the UK and some
developing countries
• The implication of ageing on the world
• Physiological changes in Elderly.
3. Age structure of population
UK 2001 census was 58,789,194 of that 18.7% above 65
Rate of increase of over 65 is by 2.4%
Currently in developed countries 165 million elderly ,
expected to increase to 265 million by 2025
Sweden highest number ,followed by the UK, Italy, Belgium
and France
Elderly before the 17th century in the UK ( Church and
charities), after the 17th century Poor Law Act, after 19th
century welfare service
By 2063, the number of 60-74 increase by 50% and over 75
by 70%, while 15-44 decline by 8%.
Life expectancy in 2004 was 81 for female and 76 for men
compared to 49 and 45
4. Developing Countries
It is a false assumption that elderly people in developing are not a problem
because they are few.
The rate of increase in the elderly population will be 15 times of that of
the UK in Colombia, the Philippines and Thailand)
France took 115 years to double their 65+ ( 7-14%) between 1865-1980,
while China takes 2000-2027 to do the same
Life expectancy at age of 65 is similar to the of developing countries
Currently have 50% of the 65+ population , estimated to increase to 75%
in 2020.
Problems with primitive, patchy health care, political instability , financial
problems , and uneven( World Trade Organisations)
Sex Developed Undeveloped
countries (years) countries (years)
Women 19 15
Men 16 12
5. India and Africa
• WHO ( Ageing in India 1999)
Life expectancy increase between 1961-2000 for both male
and female by 3-4 years ( 15.2 for men and 16.4 for women)
60-75% relies on the extended family
State pension is $1.00/month
Commonest cause of death is CHD, 60% hearing impairment,
11 million blind 80% cataract, 9M hypertension, 5M Diabetic,
4M mental health problems, 0.35 M malignancy.
Africa:- Life expectancy is less ( Cause??) , e.g Botswana in
Zimbabwe
6. The implication of aging
Healthcare
• Disabilities and multiple pathology
• Demand more need for health assistance and medical care
• More chronic diseases
• More attendance to A&E
• Longer stay
• More GP and primary care visit.
Social support
• Residential, Nursing homes and sheltered accommodation
• More carers
7. The implication of aging
Economy ( Commission on Global Ageing)
• Housing
• Transport
• Infrastructure and town planning
• Pension, employment, tax
Ethical dilemmas
Political power of elderly “ gray lobby”
8. Active ageing
WHO recommendation for active aging
Prevent premature death
Reduce disabilities associated with chronic
diseases
Ensure older people remain healthy
Encourage older people to make productive
contribution to the economy
Reduce the number requires costly medical
and care service.
9. Factors affecting active ageing
• Social factors- education/literacy/human rights/social
support/ prevention of violence.
• Personal factors- biology/genetics
• Health and social services- health promotion and
disease prevention
• Physical environment- housing urban/rural
• Economic
• Behavioural
10. Affect of the world changing on the ageing
population
• Global Warming and disasters
France (2003), Gujarat ( 2001 ), Tsunami ( 2004), Kurdistan (1991)
• Global Poverty
• Loss of Wealth more expenses for heating, housing, food...
• Retirement
11. Characteristic of Aging in the UK
• Gender
• Ethnic mix, 12% below the age of 16, 2.5% at age of 65, and only 1%
at age of 85.
• Geographical distribution- migration to villages, towns, and seaside.
• Health status:- 60% of 65+ have multiple pathologies, 37% disabling.
• Living compassions:- (in 2003) 34% of women and 19% of 65-74
years where living alone. Above 75 60% women and 30% men . Ethnic
minorities less likely to live alone
• Institution:- only 4.5% ( Nursing Homes, Residential homes), 95.5%
lives at their home including sheltered flats.
12. Physiological/psychological changes
with ageing
Skin ( physical)
• Fine wrinkles, Dryness, Laxity
• Campbell de-Morgan, seborrhoeic keratosis, cherry
haemangioma
• Greying of hair due to loss of melanin from hair follicle
• Brittle slow-grow nails
o Histological
• Atrophy of epidermis
• Reduced melanocytes, Langerhans, Mast cells,
• Reduced in function and number of sweat gland
• Thickened blood vessels
13.
14. Physiological/psychological changes
with ageing
Gastrointestinal tract
Mouth
Reduced production of saliva
Impaired muscles of mastication
Tooth loss.
Decrease in taste bud decrease in taste sensation.
Decline in sense of smell.
Enlargement of tongue and atrophic changes in jaw.
Upper GI tract
Pharyngeal muscle
Oesophageal peristalsis and lower oesophageal sphincter
Achlorydria
15. Physiological/psychological changes
with ageing
Small bowel- shortening and broadening of villi
Large Bowel
• Atrophy of mucosa
• Cell infiltration of lamina propria reduced motility and increase
• Hypertrophy of lamina muscularis transit time
• Increase in connective tissue
• Liver – reduced in volume , blood flow, and fall in liver collagen
and ascorbic acid reduce in hepatic drug metabolism but
normal LFT
• Gall Bladder- hypertrophy of muscle and elasticity of wall may reduce
• Pancreas- Deposition of amyloid , reduce lipase but no change in
amylase or bicarbonate, Duct hyperplasia Reduce fat absorption
16. Physiological/psychological changes
with ageing
Kidney:-
• Size and weight of kidney
• reduced in number and size of nephrones reduced
• reduces in number of glomeruli and more sclerotic glomeruli GFR
• Loss of lobulation of glomerular tuft with thickening of membrane
• Degenerative changes in tubules
Bladder , more trabeculation and pseudodiverticula, reduce capacity,
alteration in vasularity for submucosa ( increase risk of UTI)
Bone – thinning trabeculae due to increased osteoclastic activity
Heart
• Loss of myocytes in ventricle
• Increase in interstitial fibrosis and collagen result in LV stiffness
• Deposition of amyloid mainly in atria
• increase left atrial size
• Thickening of endocardium and valve
• reduction in pacemaker cella in SA nodes
17. Physiological/psychological changes
with ageing
o Blood vessels:- thickening of smooth muscle in arterial wall lead to
peripheral stiffness causing increase in systolic BP and widening of pulse
pressure.
Respiratory
• Reduction in no of glandular epithelial cells mucosa
secretion
• Respiratory muscles
• ossification of costal cartilage
• Thinning of alveoli
• small increase in TLC , large increase in RV and fall in FEV1,VC, and
FEV1/VC ratio
18. Physiological/psychological changes
with ageing
• Brian:- brain weight, gyri, meninges, nerve cell numbers changes
• Hearing:- loss hair and ganglion cells in choclea, decrease average
numbers of fibres in cochlear nerve. Presbyacusis ( loss of
hearing for high frequencies)
• Eyes
flatter cornea leading to astigmatism
hardening of lens and iris
floaters in vitreous humour
reduced response from ciliary muscle impaired near vision and
eyelid changes in muscle and skin astigmatism
slow response of pupils to light
19. Physiological/psychological changes
with ageing
Body temperature:-
• Inability to maintain temperature through thermo genesis.
• impaired sweating, and cutaneous vasoconstriction Hypothermia
• Impaired perception to low temperature.
Hormonal
• Insulin, oestrogen, LH/FSH, GH, Thyroid, PTH
Psychological
• Memory, intelligence, personality.
20. Specific features of disease
presentation
NAMES
N:- non specific presentation
A:- a typical or uncommon presentation
M:-multiple pathologies
E:- Erroneous attribution of symptoms in old age
S:- Single illness leading to catastrophic
consequences.
21. Non specific presentation
Described as the Dragon by Dr Trevor Howell, and the giants
of geriatric by professor Bernard Isaac. Recently geriatricians
using Is.
22. Consequences of single pathology
Bed Nursing
Falls sore care
#
Death NOF immobi Incontinence
lity
23. Pharmacology and Elderly
Drug related illness is a significant problem in the elderly.
5-17% of hospital admissions are caused by adverse reaction
to medicine. The risk of adverse reaction to medication
increases with age and the number of drugs prescribed.
Several mechanism or changes may account for this
,including:-
• Alteration of pharmacokinetic and pharmacodyanamic
• Increased sensitivity of diseases tissue to medication
• Drug interaction
• Compliance
• In appropriate prescription of medication without consideration for non
medical management, or prescribing medication causing side effect or
interacting with other medication.
24. Alteration of pharmacokinetic and
pharmacodyanamic
Renal clearance
Hepatic metabolism
Absorption is un changed
Volume distribution. Fat soluble versus water soluble.
alteration or receptors response
25. Compliance
Poor compliance in 40-75% of patients:-
• acutely ill patient can take more than prescribed dose thinking it will
speed the process of getting better
• Forgetting because of too many medication. 25% of older patient take at
least three medication. Discharged patient can be on as many as 8
medication.
• Discontinuation happens in as many as 40% of medication usually first
year.
• 10% can take medication of others and 20% non prescribed medication.
26. Clinical Assessment
Making a clinical diagnosis by:-
Taking history from patient and others. who?
Examination
• General examination and vital signs
• CVS, Respiratory, Abdomen, CNS, PNS, Musculoskeletal ands function.
• Investigation FBC, U&E, LFT, TFT, Glucose, Lipid profile, Ca/PO4,
CXR, ECG, Urinalysis.
Medication review
Cognitive function and consciousness GCS, AMTS, MMSE.
Functional assessment
Social circumstances
Environmental
Economic