This document summarizes how a Wikipedia article for the drug BMS-906024 was created through online collaboration. Carmen Drahl live blogged about new drugs at a conference, including BMS-906024. Egon Willighagen then asked Antony Williams via Twitter to deposit the drug structure in ChemSpider. Williams used ChemSpider's Wikibox function to generate content for the Wikipedia article based on the deposited ChemSpider record. The automated process updated the Wikipedia article with information from ChemSpider, demonstrating how collaborating across platforms can efficiently create new drug records in Wikipedia.

1. Blog to Wikipedia to ChemSpider
– Online Collaboration to Create
a Wikipedia Article for
BMS-906024
Antony Williams

2. The Story
• Carmen Drahl live blogged new drugs at ACS New
Orleans and a Wikipedia article was started
• Egon Willighagen asked me via Twitter to deposit
the structure into ChemSpider
• I used the Wikibox function on ChemSpider to
create the DrugBox content for Wikipedia

3. Live blogging First-Time
Disclosures of Drug Structures
•
from #ACSNOLA
http://cenblog.org/the-haystack/2013/04/liveblogging-fir
• Cannot show screenshot of Carmen’s Blog post
because it is flagged as

4. Request via Twitter

5. Draw and Save as Molfile

7. Add Info

8. Email Confirmation

9. Published to ChemSpider

10. ChemSpider Record

11. Original Wikipedia DrugBox

12. Wikipedia vs. ChemSpider
• Wikipedia
• ChemSpider

13. Wikipedia vs. ChemSpider
• Wikipedia
– O=C(N)C(CCC(F)
(F)F)C(C(=O)NC3N=C(c1ccccc1)c2ccccc2N(C3(=O))
C)CCC(F)(F)F
• ChemSpider
– CN1c2ccccc2C(=N[C@@H](C1=O)NC(=O)[C@H]
(CCC(F)(F)F)[C@H](CCC(F)(F)F)C(=O)N)c3ccccc3

14. Converted SMILES
ChemSpider SMILES Wikipedia SMILES

15. BMS-906024 on ChemSpider

16. Wikibox

17. What can be exported

18. Wikipedia Updated
• Automatically updated
by pasting DrugBox
• Systematic Name added
• ChemSpiderID added
• Mol. Mass updated
• SMILES updated

19. Conclusions
• BEST way to create new records in Wikipedia
is to deposit to ChemSpider and generate the
WikiBox from the deposited record

20. Acknowledgements
•Carmen Drahl for the live blogging!
•Egon Willighagen for the Tweet
Thank you
Email: williamsa@rsc.org
Twitter: ChemConnector
Personal Blog: www.chemconnector.com
SLIDES: www.slideshare.net/AntonyWilliams