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A Health Professionals Perspective




                                        Dr Steve

      Why Don’t G.P’s Tell their Patients to
                Eat Avocados?

Dr Steve Culpan                                                     A Paper given to the
MB Ch.B FRNZCGP Post Grad Dip Occ Med                   4th Australian and New Zealand
City Med                                                 Avocado Growers Conference
8 Albert St CBD Auckland                                                 Cairns Australia
                                                                        21 -24 July 2009



                              www.drsteve.co.nz
                                                               © Dr Steve Culpan July 2009
Doctors “know” Avocados are :
•   A “Luxury” food item – not part of every day diet

•   Expensive

•   Calorie dense, thus “fattening” in excess amount

•   High in Mono-unsaturated fats




                      www.drsteve.co.nz
                                                © Dr Steve Culpan July 2009
What are the Most Serious
  Diseases that Face a GP daily?
• High Cholesterol and Heart Disease

• Diabetes

• Obesity

• Cancer – skin/prostate/breast/bowel.


                www.drsteve.co.nz
                                    © Dr Steve Culpan July 2009
Where does a GP find Good information re
Avocados for Preventing and Treating Disease?
•   Avocado Industry Web sites :
    - www.avocado.org.au (refces unavail)
    - www.nzavocado.co.nz (useful compostion data)
    - www.olivado.com . Only 1 review article, 4 refces (2002)

•   Google “avocado” = adverts for pills

•   Pub Med - “avocado + cholesterol” = 16 papers

•   NZ/Aust Diabetes & Heart.org – cautiously restrictive



                      www.drsteve.co.nz
                                               © Dr Steve Culpan July 2009
Doctors actually don’t know that
              Avocados :
•   Lower Cholesterol
•   Low glycaemic
•   High fibre
•   1/3 calories & 1/3 fat content of butter or
    margarine. (60 - 70% as MUFA)
•   Very high in Vitamin E
•   Very high in phytosterols
                    www.drsteve.co.nz
                                          © Dr Steve Culpan July 2009
Pub-Med - Avocado + Cholesterol
              Scientific Papers
    4 papers (2 incl. diabetic patients) tested the effect of added
     dietary avocado on cholesterol, and diabetes control

•   Avocado significantly lowered LDL Cholesterol &Triglycerides while
    preserving levels of good HDL cholesterol - compared to either
    iso-caloric High Complex Carb (HCC) or Low Saturated Fat (LSF) diets

•   Added avocado had no adverse effect on diabetes control

•   Added avocado diet better compliance than HCC or LSF.

•   Added avocado never lowered the good HDL as did the LSF and HCC
    diets in some of the studies.



                         www.drsteve.co.nz
                                                     © Dr Steve Culpan July 2009
Monounsaturated Fatty Acid (avocado)
rich diet for mild hypercholesterolaemia .
    Effect of adding Avocado for 7 days, (Iso-cal 2000 kcals)
     Avocado Diet (AD) MFA 49 g. Control Diet (CD) MFA 34 g

•   In both normal and high cholesterol persons the LDL and
    Trigs dropped (13 – 22%) and the good HDL rose with
    AD, but not with the CD (p<.001% & <.01%)

•   Other studies, 2 – 4 week diets show figures of healthy
    good 10 – 15% drops in LDL cholesterol, Triglycerides,
    Total/HDL Cholesterol Ratio
    (Lopes, Frati, Hernandes et al Arch.Med. Res. 1992 Winter 23(4) 163-7.)



                           www.drsteve.co.nz
                                                           © Dr Steve Culpan July 2009
So will Avocados help the Serious
 Diseases that Face a GP daily?
High cholesterol - lowers LDL chol. and Trigs and
                     preserves/raises good HDL

Diabetes        - low glycaemic plus helps cholesterol
                     without upsetting diabetes control

Obesity         – low glycaemic high fibre and
                     lower calories than butter/margarine.

Cancer          – very high in Vitamin E and physterols.


                   www.drsteve.co.nz
                                           © Dr Steve Culpan July 2009
Your Challenge?
• To change GPs from “passive” to “active” promoters for
  their patients regularly eating avocados, by -

• Dispelling the luxury, expensive, calorie dense” myth,
                   and –
• Making easily available to the GP, information and
  knowledge of the Avocado’s role as a “food medicine” to
  be safely and actively added to patients who may have
  obesity, or high cholesterol or diabetes




                   www.drsteve.co.nz
                                           © Dr Steve Culpan July 2009
Your maths?
• If 10% of population have high cholesterol
  or diabetes and eat just 1 avocado a week
  to help “treat” these illnesses, then for

• 22 million Aussies and 4 million Kiwis,

• How many trays do not have to be
  exported each year ?

               www.drsteve.co.nz
                                   © Dr Steve Culpan July 2009
Growers Beware!
 Most studies of isolated food compounds fail to show any
 benefits when given in tablet form, and some show harm

Vitamin A Retinol                      - 16% increased risk of death

Vitamin A B-Carotene - 7 %                           increased risk of death

Vitamin E                              - 4%           increased risk of death

(Antioxidant Supplements for prevention of Mortality in Healthy Participants and Patients with various
  Diseases. Bjelakovic et al. Cochrane Database of Systematic Reviews 2008 Issue 2. 16th April 2008)




                                 www.drsteve.co.nz
                                                                           © Dr Steve Culpan July 2009

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Steve Culpan

  • 1. A Health Professionals Perspective Dr Steve Why Don’t G.P’s Tell their Patients to Eat Avocados? Dr Steve Culpan A Paper given to the MB Ch.B FRNZCGP Post Grad Dip Occ Med 4th Australian and New Zealand City Med Avocado Growers Conference 8 Albert St CBD Auckland Cairns Australia 21 -24 July 2009 www.drsteve.co.nz © Dr Steve Culpan July 2009
  • 2. Doctors “know” Avocados are : • A “Luxury” food item – not part of every day diet • Expensive • Calorie dense, thus “fattening” in excess amount • High in Mono-unsaturated fats www.drsteve.co.nz © Dr Steve Culpan July 2009
  • 3. What are the Most Serious Diseases that Face a GP daily? • High Cholesterol and Heart Disease • Diabetes • Obesity • Cancer – skin/prostate/breast/bowel. www.drsteve.co.nz © Dr Steve Culpan July 2009
  • 4. Where does a GP find Good information re Avocados for Preventing and Treating Disease? • Avocado Industry Web sites : - www.avocado.org.au (refces unavail) - www.nzavocado.co.nz (useful compostion data) - www.olivado.com . Only 1 review article, 4 refces (2002) • Google “avocado” = adverts for pills • Pub Med - “avocado + cholesterol” = 16 papers • NZ/Aust Diabetes & Heart.org – cautiously restrictive www.drsteve.co.nz © Dr Steve Culpan July 2009
  • 5. Doctors actually don’t know that Avocados : • Lower Cholesterol • Low glycaemic • High fibre • 1/3 calories & 1/3 fat content of butter or margarine. (60 - 70% as MUFA) • Very high in Vitamin E • Very high in phytosterols www.drsteve.co.nz © Dr Steve Culpan July 2009
  • 6. Pub-Med - Avocado + Cholesterol Scientific Papers 4 papers (2 incl. diabetic patients) tested the effect of added dietary avocado on cholesterol, and diabetes control • Avocado significantly lowered LDL Cholesterol &Triglycerides while preserving levels of good HDL cholesterol - compared to either iso-caloric High Complex Carb (HCC) or Low Saturated Fat (LSF) diets • Added avocado had no adverse effect on diabetes control • Added avocado diet better compliance than HCC or LSF. • Added avocado never lowered the good HDL as did the LSF and HCC diets in some of the studies. www.drsteve.co.nz © Dr Steve Culpan July 2009
  • 7. Monounsaturated Fatty Acid (avocado) rich diet for mild hypercholesterolaemia . Effect of adding Avocado for 7 days, (Iso-cal 2000 kcals) Avocado Diet (AD) MFA 49 g. Control Diet (CD) MFA 34 g • In both normal and high cholesterol persons the LDL and Trigs dropped (13 – 22%) and the good HDL rose with AD, but not with the CD (p<.001% & <.01%) • Other studies, 2 – 4 week diets show figures of healthy good 10 – 15% drops in LDL cholesterol, Triglycerides, Total/HDL Cholesterol Ratio (Lopes, Frati, Hernandes et al Arch.Med. Res. 1992 Winter 23(4) 163-7.) www.drsteve.co.nz © Dr Steve Culpan July 2009
  • 8. So will Avocados help the Serious Diseases that Face a GP daily? High cholesterol - lowers LDL chol. and Trigs and preserves/raises good HDL Diabetes - low glycaemic plus helps cholesterol without upsetting diabetes control Obesity – low glycaemic high fibre and lower calories than butter/margarine. Cancer – very high in Vitamin E and physterols. www.drsteve.co.nz © Dr Steve Culpan July 2009
  • 9. Your Challenge? • To change GPs from “passive” to “active” promoters for their patients regularly eating avocados, by - • Dispelling the luxury, expensive, calorie dense” myth, and – • Making easily available to the GP, information and knowledge of the Avocado’s role as a “food medicine” to be safely and actively added to patients who may have obesity, or high cholesterol or diabetes www.drsteve.co.nz © Dr Steve Culpan July 2009
  • 10. Your maths? • If 10% of population have high cholesterol or diabetes and eat just 1 avocado a week to help “treat” these illnesses, then for • 22 million Aussies and 4 million Kiwis, • How many trays do not have to be exported each year ? www.drsteve.co.nz © Dr Steve Culpan July 2009
  • 11. Growers Beware! Most studies of isolated food compounds fail to show any benefits when given in tablet form, and some show harm Vitamin A Retinol - 16% increased risk of death Vitamin A B-Carotene - 7 % increased risk of death Vitamin E - 4% increased risk of death (Antioxidant Supplements for prevention of Mortality in Healthy Participants and Patients with various Diseases. Bjelakovic et al. Cochrane Database of Systematic Reviews 2008 Issue 2. 16th April 2008) www.drsteve.co.nz © Dr Steve Culpan July 2009