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Akron Biomedical Corridor




                            1
2
3
Ohio Market Sectors

     Agricultural                                                             Research, Testing, &
Feedstock & Chemicals       Drugs &        Medical Devices      Hospitals     Medical Laboratories
                         Pharmaceuticals    & Equipment
   Agricultural                                                                Biological
   processing                               Laboratory        Specialty
                         Medicinal         apparatus &                         research
                                                               hospitals
   Basic organic       &                   furniture                           Commercial
   chemicals             botanicals                            University      medical
                                            Surgical,         medical
   Ethyl alcohol        Pharma-          medical, dental,                     research
    mfg.                                                       research
                          ceutical         ophthalmic          hospitals        Testing
   Organic fiber         preparation      & analytical                         laboratories
    mfg.                s                  instruments &       Clinical
                                           equipment           research         Medical
   Fertilizers          Diagnostic                           institutions      laboratories
                         substances         Irradiation                       &
   Pesticides and                          apparatus &
   other                 Biological                                             diagnostic
                                            electromedical                       imaging
  agricultural           products
   chemicals                                equipment                            centers
                        Product-Oriented                              Service -Oriented


                                                                                                4
There are approx.50 orthopedic companies in NEO;
                                                                  Other global players are within 3-4 hours drive.

* Total Ohio bioscience establishments are 1141 (March 1, 2009)


                                                                                                                5
6
Ohio By-The-Numbers, Then
                                          & Now

                                      Indicator                               Then                          Now             Growth

Bioscience Companies                                                       170 (1991)                   1,318 (2010)        7.75x


Company Locations                                                         1,302 (2000)                  1,743 (2011)        1.34x


Bioscience Employees                                                      52,062 (2000)                 60,636 (2011)       1.16x


                                                                                                           79 (2010)
Company Starts per Year                                                     46 (2000)                                        1.7x
                                                                                                    68/yr (AVG 2000-2010)


Company Expansions                                                          16 (2005)                     56 (2011)          3.5x


National Institutes of Health (NIH)                                      $470 M (2005)                 $711 M (2011)         1.5x


Small Business Association (SBIR/STTR)                                    $8 M (2000)                  $24.5 M (2010)        3.1x


National Science Foundation (NSF BIO)                                     $9.3 M (2000)                $14.8 M (2011)        1.6x


Private Capital Raised (excluding acquisitions, IPO)                      $14 M (2001)                 $217 M (2011)        15.5x


Companies Receiving Private Capital (including acquisitions, IPO)           12 (2004)                    102 (2011)          8.5x


Ohio Based Bioscience Capital Sources                                       4 (1991)                      91 (2012)          7.6x


BioOhio Membership                                                          52 (1991)                    420 (2012)          4.9x


Bioscience Related Patents                                                 499 (2004)                    685 (2011)          1.4x

   NIH, SBIR/STTR, NSF awards included based on relevance to bioscience and life-science fields, non-bio related
  awards are excluded. Dollar figures are historical, not adjusted for inflation. Sources include research conducted by
         BioOhio and its partners. Data or specific sources available upon request. Table updated July 2012.


                                                                                                                                     7
Ohio Third Frontier Program
                    10 year, $1.6 billion, 60% funding into Biosciences
Commercialization Framework




             Programmatic Focus




                                                                          8
Third Frontier Project


   Ohio’s 10-year, $1.6 billion Third Frontier Project launched in February 2002. This project is the state’s largest ever
   commitment to expanding high-tech research capabilities and promoting innovation and company formation to
   create high-paying jobs.

   In May 2010, Ohioans voted to extend the Third Frontier Project with an additional $700 million over four years
   starting in 2012.

   Since 2002 over 100 diverse bioscience-related projects have been funded. In 2011, 28 new bioscience projects
   were funded by the Third Frontier, totaling over $40 million and matched by more than $42 million in private funding.

                 Ohio Third Frontier Bioscience Awards by Year

       Year           Number of Awards               Award               Matching
       2002                     10                   $35.84                $67.25
                                                                                            For more information and
       2003                     8                    $48.48               $100.58
       2004                     5                    $45.65                $76.06
                                                                                            metrics on the Ohio Third
       2005                     7                    $75.35               $112.45           Frontier Project, visit:
       2006                     10                   $154.73              $273.80
       2007                     8                    $135.24               $92.16
       2008                     18                   $98.30               $105.45               www.thirdfrontier.com
       2009                     9                    $39.68                $46.00
       2010                     27                   $55.63                $83.74
       2011                     28                    40.94                $42.31
      Total                    130                   $729.84              $999.82
* This table includes awards from multiple OTF programs, including the OTF Biomedical and
OTF Medical Imaging programs.



                                                                                                                             9
25.   Foundation Medical Partners    50.   Scius (Spire Capital)
1.    Adena Ventures                        26.   Frantz Medical Ventures        51.   Soin International
2.    Akron ArchAngels Network              27.   Glengary Ventures              52.   RMS Investments
3.    Alpha Capital Partners                28.   GLIDE Fund                     53.   Rocket Ventures
4.    Arboretum Ventures                    29.   iNetwork BioOpportunity        54.   Southern Ohio Creates Capital
5.    Athenian Ventures                     30.   Innovation Fund of LCCC        55.   Summit Health Ventures
6.    Battelle Ventures                     31.   Isabella Capital               56.   Sycamore Partners
7.    Blue Chip Venture Company             32.   JumpStart                      57.   Talisman Capital
8.    Blue Point Capital                    33.   Kadima Partners                58.   TechColumbus TechGenesis
9.    Bridge Investment Fund                34.   Miami Valley Ventures          59.   TechColumbus RCF
10.   Case Technology Ventures              35.   Morgenthaler Ventures          60.   Teton Capital
11.   Charter Life Sciences                 36.   Mutual Capital                 61.   Triathlon Medical Ventures
12.   Chrysalis Ventures                    37.   NCIC Capital
13.   CID Equity Partners                   38.   NCT Ventures
14.   Cincinnati Children's Tomorrow Fund   39.   North Coast Angels
                                                                                 Ohio Health Care
                                                                                 Venture
15.   CincyTech Ventures                    40.   Oakwood Medical
16.   Cleveland Clinic Innovations          41.   Ohio Tech Angels I, II & III
17.   Core Network                          42.   Primus Capital
                                                                                 Funds…More
                                                                                 than 100 have
18.   Draper Triangle Ventures              43.   Queen City Angels
19.   Early Stage Partners                  44.   Radius Ventures

                                                                                 invested into
20.   Edgewater Capital                     45.   Redwood Holdings
21.   Entrepreneurs “E” Fund                46.   Reservoir Ventures
22.   Everett Partners                      47.   River Cities Capital Funds
                                                                                 Ohio bioscience
                                                                                 companies
23.   Fletecher Spaght                      48.   Riverside Capital
24.   Fort Washington Capital               49.   Rivervest Ventures




                                                                                                                       10
11
Average Annual Percentage Change in Employment, Establishments,
                             Payroll & Average Wages for the Northeast Region


                                                                          Northeast Ohio
                                                                           In 2011, the region accounted for 35% of
                                                                           the total bioscience employment (21,029),
                                                                           37% of the total bioscience payroll ($1.7
                                                                           billion), and 42% of the total number of
                                                                           bioscience locations (729). From 2000 to
                                                                           2011, the northeast region consistently
                                                                           reported the highest bioscience
                                                                           employment, payroll, and number of
                                                                           locations of any Ohio region.




                 Employment, Payroll, Average Wages, and Locations, Northeast Region, 2011

                 Subsector                       Employment              Payroll ($)           Average Wages ($)   Locations

Agricultural Biotechnology                           3,812             $575,893,356                $151,074           58
Medical & Testing Laboratories                       3,301             $162,293,524                $49,165           238
Medical Device & Equipment                           9,500             $594,038,200                $62,530           293
Pharmaceuticals & Therapeutics                       2,576             $226,318,095                $87,856            30
Research & Development                               1,840             $142,537,048                $77,466           110
Total                                               21,029            $1,701,080,223               $80,892           729


                                                                                                                               12
Northeast Ohio
                                                        Economic Impact of Bioscience, 2010

      Impact             Employment                     Output         Value Added     Labor Income
      Direct                 20,719                $11,438.61           $1,464.24        $413.31
     Indirect                29,580                 $4,989.48           $2,573.60        $1,612.38
     Induced                 15,994                 $1,768.81           $1,070.13        $595.38
       Total                 66,293                $18,196.90           $5,107.97        $2,621.08
Output, Value Added, and Labor Income are in millions


Economic Impact of Bioscience by Subsector, 2010
               Subsector                 Employment               Output       Value Added Labor Income          Tax
 Agricultural Biotechnology                  23,628              $9,016.24      $2,035.63          $1,071.77   $467.35
 Medical & Testing Laboratories               5753                $657.25           $227.15          $133.69    $45.96
 Medical Device & Equipment                  18559               $3,971.75      $1,336.17            $577.21   $241.93
 Pharmaceuticals & Therapeutics              15204               $4,149.92      $1,379.53            $745.62   $279.86
 Research & Development                       3149                $401.75           $129.49          $92.78     $28.31
 Total                                       66,293              $18,196.90     $5,107.97          $2,621.08   $1,063.42
Output, Value Added, Labor Income, and Tax are in millions




                                                                                                                           13
3 cities in the top 40 Biotech locations in USA


                             #4 in biotechnology
                             industry strength in
                             2008

                     State City                        Rank

                     OH       Cleveland-Akron 20

                              Columbus                 22
                              Cincinnati               28

                      All three cities rank higher than the 100
                        city average in Research grant awards
                                     in Bio- Sciences
                       $630 Million in NIH Awards in 2008!


                                                                  14
Akron is the place to be for
Life Science Companies




                               15
The Akron Biomedical Corridor
•   Established by the Mayor in July 2006 following a business mission to Israel
•   Akron is well positioned to develop a world class biomedical innovation
    district given its research, healthcare and community assets.
•   500+ acre area which arcs around downtown Akron
•   Links
     – Three world-class hospitals
         • Summa Health System
         • Akron General Medical Center        More beds than the
         • Akron Children’s Hospital           Clev. Clinic or UH
     – The Austen Bioinnovation Institute in Akron (ABIA)
         •   Center for Biomaterials and Medicine
         •   Medical Device Development Center
         •   Center for Simulation and Integrated Healthcare Education
         •   Center for Clinical Trials and Product Development
         •   Center for Community Health Improvement
     – The University of Akron
         • Top Polymers and Biomaterials programs

                                                                                   16
The Akron Biomedical Corridor(Cont.)

• Effective collaboration of 3 health systems, the U of Akron,
  ABIA, NEOMED, Summit County, the Chamber, private
  businesses and not for profit organizations( Knight
  Foundation, UPA)

• Provides strategic geographic location for biomedical
  technologies, products, services, R&D, business
  development as well as clinical trials and test marketing

• The State designation of Akron as an Ohio Hub of
  Innovations and Opportunity for Biomaterials
  Commercialization offers the potential for greater
  recognition and attraction power


                                                                 17
Akron Biomaterials
Commercialization Hub




                        18
                             18
Vision and Mission

Vision
  Become a globally recognized leader in commercialization
  of innovative biomedical technologies, products and
  services resulting in improved patient care, job creation,
  wealth creation and redevelopment of the City’s urban core.
Mission
  Leverage Greater Akron healthcare and community
  strengths to attract , support and grow biomedical
  technologies and businesses




                                                                19
Akron’s Biomedical Assets
   Three nationally ranked healthcare systems (2 adult; 1 children)
       Over 20,000 physicians, specialists and staff
       Nearly 1300 beds
       Over 1.5 M annual outpatient visits
       Over 65,000 patient admissions
   Outstanding research and medical institutions
       The University of Akron with top national polymer college with outstanding
        materials and biopolymers science and technology
       NEOMED medical school with strong research in skeletal biology
       ABIA (Austen Bioinnovation Institute in Akron)
   Numerous innovative companies and advanced research
     institutions with following areas of focus:
       Orthopedics; Advanced burn, wound care and tissue engineering
       Chronic diseases; Imaging and diagnostics
       Pediatrics; Skin hygiene, anti microbial formulations and delivery devices
       Supply chain support
   Northeastern Ohio Consortium for Wound Healing Research and Education
    (Heal Ohio™ Collaborative)
   Ohio and the region are home to the highest concentration of health care
    VC firms between the coasts, top 5 in the country.
       Increased activity of local investment groups (GAIP, Everett Partners,
        ArchAngels, et al)
       Akron BioInvestments Funds
       Strong public-private partnerships (stability and continuity of leadership)



                                                                                      20
Akron Global Business Accelerator
      Proven Economic Results in the center
      NEOinc Tenants (FY08-11)

      •   $203 Million—Total Sales Revenue
      •   $63 Million—Total Investment
      •   382 Jobs Created
      •   $59 Million—Total Payroll
      •   21 Patents Issued
      • 90:1 Leverage

*(Sales Revenue + Investment)/Edison Funding



                                               21
                                                    21
Akron’s Competitive Advantage
  …. Translates into your “benevants”

• The Akron community has a proven history of
  innovation and transformation
• Our community it ―tight‖
• Our community is the portal
• You are at the ―head of the line‖ to all that the
  region offers



                                                      22
THE BRIDGES WE ARE CREATING

        The BioFinland Bridge
         The Chemnitz Bridge
     The Israeli Targetech Bridge
          The LeMans Bridge
      Others under development




                                    23
Shared Values

• Flat world- never too early for international
  cooperation
• BioScience/BioAgricultural/Cleantech sectors key
  to a healthy society
• Power of ―team approach‖ … a people to people
  business based on mutual trust with ―boots on the
  ground‖
• International collaboration is not new for Ohio
• Leveraging existing networks is beneficial to both


                                                       24
Why are we building bridges?
 • Create a two-way informational networking infrastructure to
   facilitate cooperation and business-economic development
 • Increase basic science, R&D and clinical collaborations
   between Ohio and institutions, researchers and companies
   globally
 • Advance work force development, education and training
   through exchange programs, professional delegations and
   conferences
 • Develop an international bridge fund to help early stage
   companies ready to expand outside of their existing market
 • Reduce risk




                                                                 25
KEY SUCCESS
 CHARACTERISTICS
• IDENTIFY INTERNATIONAL INNOVATION CENTERS THAT
  MATCH UP WITH AKRON STRATEGY AND ASSETS

• AREAS THAT ARE HUNGRY FOR CHANGE

• AREAS WILLING TO TAKE A RISK/CAN DO ATTITUDE

• AREAS WITH LIMITED BUREAUCRATIC BARRIERS

• AREAS WILLING TO INVEST RESOURCES

• AREAS THAT HAVE BUSINESS DEVELOPMENT ASSISTANCE
  STRUCTURES AND NETWORKS IN PLACE

                                                    26
Key Success Factors &
Lessons Learned
• Define & clarify universal needs
• Take the time to build a strong
 team
• Be sure actions are two way
• Soft landing zones should be ―sticky‖
• Public-private partnerships needed
• Consistency and stability in leadership
• ―Boots on the ground‖ make the difference



                                              27
Flow Diagram
                                 Bio-Finland Technology Bridge

R&D
-University                                                                                             R&D
-Hospital                                          Networking                                           -University
-Labs                                                                                                   -Hospital
                                                    Bridge                                              -Labs
Bus. Dev.                                                                                               Bus. Dev.
-Company         Qualified                             R&D                            Qualified
                                     HBSP                            AGBA                               -Company
-Consultant     Early Stage                                                          Early Stage
                 Company            Radvisor            BD          REA Inc           Company           -Consultant

$$                                                      $$                                              $$
-Public                                                                                                 -Public
-Private                                                                                                -Private


Soft Landing Zone                                                                       Soft Landing Zone
  (Defined by Agreements)                                                                (Defined by Agreements)



                            Stakeholders
                            City/State Economic Development- fund start up and operations
                            Companies- fund incentive (transaction) based aspects with fees & success sharing

                                                                                                                      28
Akron and Helsinki are “soft landing zones” and Portal Cities to larger markets

              Akron                                             Helsinki

    Soft Landing Zone
       Biomedical Corridor                              Soft Landing Zone
 Akron Global Business Accelerator                   Helsinki Business & Science Park
          Akron Chamber                                      Viikki Food Center
          Akron General                                          Culminatum
              Summa                                Ministry of Employment & Technology
         Akron Children’s                                Greater Helsinki Promotion
            NEOUCOM                                                   VTT
            U of Akron                                       Biomedicum 1,2,3
            Kent State                                      University of Helsinki
               ABIA                                                  Tekes
              ODOD                                                   Sittra
               ADC                                               Veraventure
          Angel networks                                            Inventi
              Others                                                Others


         Ohio and North                                        Finland and
            America                                                 EU
                                                                                         29
AKRON’S FUTURE
•   TO CONTINUE OUR LEGACY AS A CITY THAT REINVENTS
    ITSELF

•   TO ACCELERATE THE TRANSITION TO THE KNOWLEDGE
    ECONOMY

•   TO TAKE ADVANTAGE OF ITS FOUNDATION CLUSTERS
    BY FOCUSING ON BIOMATERIALS,ORTHOPAEDICS,
    WOUND CARE AND BIOMEDICAL DEVICES

•   TO CONTINUE TO BE A PLAYER IN THE WORLD
    ECONOMY

•   TO ATTRACT WORLD-CLASS TECHNOLOGIES AND
    TALENT



                                                      30
What Can We Do To Help?
Akron Global Business             City of Akron
Accelerator                       Robert Y. Bowman
526 South Main Street             Deputy Mayor, Economic Development
Akron, Ohio 44311                 330-375-2133

Robert E. Anthony                 Sam DeShazior
PH: 330-571-0574                  Deputy Planning Director
ranth44341@aol.com                SDeShazior@AkronOhio.gov

www.akronbiomedicalcorridor.com   The Akron BioMedical Corridor
www.akronaccelerator.com          Dr. Zev Gurion
www.ci.akron.oh.us                Executive Director
                                  330-258-0120
                                  zgurion@akronbiomedicalcorridor.com

                                                                   31

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Akron BioMedical Corridor Overview

  • 2. 2
  • 3. 3
  • 4. Ohio Market Sectors Agricultural Research, Testing, & Feedstock & Chemicals Drugs & Medical Devices Hospitals Medical Laboratories Pharmaceuticals & Equipment  Agricultural  Biological processing  Laboratory  Specialty  Medicinal apparatus & research hospitals  Basic organic & furniture  Commercial chemicals botanicals  University medical  Surgical, medical  Ethyl alcohol  Pharma- medical, dental, research mfg. research ceutical ophthalmic hospitals  Testing  Organic fiber preparation & analytical laboratories mfg. s instruments &  Clinical equipment research  Medical  Fertilizers  Diagnostic institutions laboratories substances  Irradiation &  Pesticides and apparatus & other  Biological diagnostic electromedical imaging agricultural products chemicals equipment centers Product-Oriented Service -Oriented 4
  • 5. There are approx.50 orthopedic companies in NEO; Other global players are within 3-4 hours drive. * Total Ohio bioscience establishments are 1141 (March 1, 2009) 5
  • 6. 6
  • 7. Ohio By-The-Numbers, Then & Now Indicator Then Now Growth Bioscience Companies 170 (1991) 1,318 (2010) 7.75x Company Locations 1,302 (2000) 1,743 (2011) 1.34x Bioscience Employees 52,062 (2000) 60,636 (2011) 1.16x 79 (2010) Company Starts per Year 46 (2000) 1.7x 68/yr (AVG 2000-2010) Company Expansions 16 (2005) 56 (2011) 3.5x National Institutes of Health (NIH) $470 M (2005) $711 M (2011) 1.5x Small Business Association (SBIR/STTR) $8 M (2000) $24.5 M (2010) 3.1x National Science Foundation (NSF BIO) $9.3 M (2000) $14.8 M (2011) 1.6x Private Capital Raised (excluding acquisitions, IPO) $14 M (2001) $217 M (2011) 15.5x Companies Receiving Private Capital (including acquisitions, IPO) 12 (2004) 102 (2011) 8.5x Ohio Based Bioscience Capital Sources 4 (1991) 91 (2012) 7.6x BioOhio Membership 52 (1991) 420 (2012) 4.9x Bioscience Related Patents 499 (2004) 685 (2011) 1.4x NIH, SBIR/STTR, NSF awards included based on relevance to bioscience and life-science fields, non-bio related awards are excluded. Dollar figures are historical, not adjusted for inflation. Sources include research conducted by BioOhio and its partners. Data or specific sources available upon request. Table updated July 2012. 7
  • 8. Ohio Third Frontier Program 10 year, $1.6 billion, 60% funding into Biosciences Commercialization Framework Programmatic Focus 8
  • 9. Third Frontier Project Ohio’s 10-year, $1.6 billion Third Frontier Project launched in February 2002. This project is the state’s largest ever commitment to expanding high-tech research capabilities and promoting innovation and company formation to create high-paying jobs. In May 2010, Ohioans voted to extend the Third Frontier Project with an additional $700 million over four years starting in 2012. Since 2002 over 100 diverse bioscience-related projects have been funded. In 2011, 28 new bioscience projects were funded by the Third Frontier, totaling over $40 million and matched by more than $42 million in private funding. Ohio Third Frontier Bioscience Awards by Year Year Number of Awards Award Matching 2002 10 $35.84 $67.25 For more information and 2003 8 $48.48 $100.58 2004 5 $45.65 $76.06 metrics on the Ohio Third 2005 7 $75.35 $112.45 Frontier Project, visit: 2006 10 $154.73 $273.80 2007 8 $135.24 $92.16 2008 18 $98.30 $105.45 www.thirdfrontier.com 2009 9 $39.68 $46.00 2010 27 $55.63 $83.74 2011 28 40.94 $42.31 Total 130 $729.84 $999.82 * This table includes awards from multiple OTF programs, including the OTF Biomedical and OTF Medical Imaging programs. 9
  • 10. 25. Foundation Medical Partners 50. Scius (Spire Capital) 1. Adena Ventures 26. Frantz Medical Ventures 51. Soin International 2. Akron ArchAngels Network 27. Glengary Ventures 52. RMS Investments 3. Alpha Capital Partners 28. GLIDE Fund 53. Rocket Ventures 4. Arboretum Ventures 29. iNetwork BioOpportunity 54. Southern Ohio Creates Capital 5. Athenian Ventures 30. Innovation Fund of LCCC 55. Summit Health Ventures 6. Battelle Ventures 31. Isabella Capital 56. Sycamore Partners 7. Blue Chip Venture Company 32. JumpStart 57. Talisman Capital 8. Blue Point Capital 33. Kadima Partners 58. TechColumbus TechGenesis 9. Bridge Investment Fund 34. Miami Valley Ventures 59. TechColumbus RCF 10. Case Technology Ventures 35. Morgenthaler Ventures 60. Teton Capital 11. Charter Life Sciences 36. Mutual Capital 61. Triathlon Medical Ventures 12. Chrysalis Ventures 37. NCIC Capital 13. CID Equity Partners 38. NCT Ventures 14. Cincinnati Children's Tomorrow Fund 39. North Coast Angels Ohio Health Care Venture 15. CincyTech Ventures 40. Oakwood Medical 16. Cleveland Clinic Innovations 41. Ohio Tech Angels I, II & III 17. Core Network 42. Primus Capital Funds…More than 100 have 18. Draper Triangle Ventures 43. Queen City Angels 19. Early Stage Partners 44. Radius Ventures invested into 20. Edgewater Capital 45. Redwood Holdings 21. Entrepreneurs “E” Fund 46. Reservoir Ventures 22. Everett Partners 47. River Cities Capital Funds Ohio bioscience companies 23. Fletecher Spaght 48. Riverside Capital 24. Fort Washington Capital 49. Rivervest Ventures 10
  • 11. 11
  • 12. Average Annual Percentage Change in Employment, Establishments, Payroll & Average Wages for the Northeast Region Northeast Ohio In 2011, the region accounted for 35% of the total bioscience employment (21,029), 37% of the total bioscience payroll ($1.7 billion), and 42% of the total number of bioscience locations (729). From 2000 to 2011, the northeast region consistently reported the highest bioscience employment, payroll, and number of locations of any Ohio region. Employment, Payroll, Average Wages, and Locations, Northeast Region, 2011 Subsector Employment Payroll ($) Average Wages ($) Locations Agricultural Biotechnology 3,812 $575,893,356 $151,074 58 Medical & Testing Laboratories 3,301 $162,293,524 $49,165 238 Medical Device & Equipment 9,500 $594,038,200 $62,530 293 Pharmaceuticals & Therapeutics 2,576 $226,318,095 $87,856 30 Research & Development 1,840 $142,537,048 $77,466 110 Total 21,029 $1,701,080,223 $80,892 729 12
  • 13. Northeast Ohio Economic Impact of Bioscience, 2010 Impact Employment Output Value Added Labor Income Direct 20,719 $11,438.61 $1,464.24 $413.31 Indirect 29,580 $4,989.48 $2,573.60 $1,612.38 Induced 15,994 $1,768.81 $1,070.13 $595.38 Total 66,293 $18,196.90 $5,107.97 $2,621.08 Output, Value Added, and Labor Income are in millions Economic Impact of Bioscience by Subsector, 2010 Subsector Employment Output Value Added Labor Income Tax Agricultural Biotechnology 23,628 $9,016.24 $2,035.63 $1,071.77 $467.35 Medical & Testing Laboratories 5753 $657.25 $227.15 $133.69 $45.96 Medical Device & Equipment 18559 $3,971.75 $1,336.17 $577.21 $241.93 Pharmaceuticals & Therapeutics 15204 $4,149.92 $1,379.53 $745.62 $279.86 Research & Development 3149 $401.75 $129.49 $92.78 $28.31 Total 66,293 $18,196.90 $5,107.97 $2,621.08 $1,063.42 Output, Value Added, Labor Income, and Tax are in millions 13
  • 14. 3 cities in the top 40 Biotech locations in USA #4 in biotechnology industry strength in 2008 State City Rank OH Cleveland-Akron 20 Columbus 22 Cincinnati 28 All three cities rank higher than the 100 city average in Research grant awards in Bio- Sciences $630 Million in NIH Awards in 2008! 14
  • 15. Akron is the place to be for Life Science Companies 15
  • 16. The Akron Biomedical Corridor • Established by the Mayor in July 2006 following a business mission to Israel • Akron is well positioned to develop a world class biomedical innovation district given its research, healthcare and community assets. • 500+ acre area which arcs around downtown Akron • Links – Three world-class hospitals • Summa Health System • Akron General Medical Center More beds than the • Akron Children’s Hospital Clev. Clinic or UH – The Austen Bioinnovation Institute in Akron (ABIA) • Center for Biomaterials and Medicine • Medical Device Development Center • Center for Simulation and Integrated Healthcare Education • Center for Clinical Trials and Product Development • Center for Community Health Improvement – The University of Akron • Top Polymers and Biomaterials programs 16
  • 17. The Akron Biomedical Corridor(Cont.) • Effective collaboration of 3 health systems, the U of Akron, ABIA, NEOMED, Summit County, the Chamber, private businesses and not for profit organizations( Knight Foundation, UPA) • Provides strategic geographic location for biomedical technologies, products, services, R&D, business development as well as clinical trials and test marketing • The State designation of Akron as an Ohio Hub of Innovations and Opportunity for Biomaterials Commercialization offers the potential for greater recognition and attraction power 17
  • 19. Vision and Mission Vision Become a globally recognized leader in commercialization of innovative biomedical technologies, products and services resulting in improved patient care, job creation, wealth creation and redevelopment of the City’s urban core. Mission Leverage Greater Akron healthcare and community strengths to attract , support and grow biomedical technologies and businesses 19
  • 20. Akron’s Biomedical Assets  Three nationally ranked healthcare systems (2 adult; 1 children)  Over 20,000 physicians, specialists and staff  Nearly 1300 beds  Over 1.5 M annual outpatient visits  Over 65,000 patient admissions  Outstanding research and medical institutions  The University of Akron with top national polymer college with outstanding materials and biopolymers science and technology  NEOMED medical school with strong research in skeletal biology  ABIA (Austen Bioinnovation Institute in Akron)  Numerous innovative companies and advanced research institutions with following areas of focus:  Orthopedics; Advanced burn, wound care and tissue engineering  Chronic diseases; Imaging and diagnostics  Pediatrics; Skin hygiene, anti microbial formulations and delivery devices  Supply chain support  Northeastern Ohio Consortium for Wound Healing Research and Education (Heal Ohio™ Collaborative)  Ohio and the region are home to the highest concentration of health care VC firms between the coasts, top 5 in the country.  Increased activity of local investment groups (GAIP, Everett Partners, ArchAngels, et al)  Akron BioInvestments Funds  Strong public-private partnerships (stability and continuity of leadership) 20
  • 21. Akron Global Business Accelerator Proven Economic Results in the center NEOinc Tenants (FY08-11) • $203 Million—Total Sales Revenue • $63 Million—Total Investment • 382 Jobs Created • $59 Million—Total Payroll • 21 Patents Issued • 90:1 Leverage *(Sales Revenue + Investment)/Edison Funding 21 21
  • 22. Akron’s Competitive Advantage …. Translates into your “benevants” • The Akron community has a proven history of innovation and transformation • Our community it ―tight‖ • Our community is the portal • You are at the ―head of the line‖ to all that the region offers 22
  • 23. THE BRIDGES WE ARE CREATING The BioFinland Bridge The Chemnitz Bridge The Israeli Targetech Bridge The LeMans Bridge Others under development 23
  • 24. Shared Values • Flat world- never too early for international cooperation • BioScience/BioAgricultural/Cleantech sectors key to a healthy society • Power of ―team approach‖ … a people to people business based on mutual trust with ―boots on the ground‖ • International collaboration is not new for Ohio • Leveraging existing networks is beneficial to both 24
  • 25. Why are we building bridges? • Create a two-way informational networking infrastructure to facilitate cooperation and business-economic development • Increase basic science, R&D and clinical collaborations between Ohio and institutions, researchers and companies globally • Advance work force development, education and training through exchange programs, professional delegations and conferences • Develop an international bridge fund to help early stage companies ready to expand outside of their existing market • Reduce risk 25
  • 26. KEY SUCCESS CHARACTERISTICS • IDENTIFY INTERNATIONAL INNOVATION CENTERS THAT MATCH UP WITH AKRON STRATEGY AND ASSETS • AREAS THAT ARE HUNGRY FOR CHANGE • AREAS WILLING TO TAKE A RISK/CAN DO ATTITUDE • AREAS WITH LIMITED BUREAUCRATIC BARRIERS • AREAS WILLING TO INVEST RESOURCES • AREAS THAT HAVE BUSINESS DEVELOPMENT ASSISTANCE STRUCTURES AND NETWORKS IN PLACE 26
  • 27. Key Success Factors & Lessons Learned • Define & clarify universal needs • Take the time to build a strong team • Be sure actions are two way • Soft landing zones should be ―sticky‖ • Public-private partnerships needed • Consistency and stability in leadership • ―Boots on the ground‖ make the difference 27
  • 28. Flow Diagram Bio-Finland Technology Bridge R&D -University R&D -Hospital Networking -University -Labs -Hospital Bridge -Labs Bus. Dev. Bus. Dev. -Company Qualified R&D Qualified HBSP AGBA -Company -Consultant Early Stage Early Stage Company Radvisor BD REA Inc Company -Consultant $$ $$ $$ -Public -Public -Private -Private Soft Landing Zone Soft Landing Zone (Defined by Agreements) (Defined by Agreements) Stakeholders City/State Economic Development- fund start up and operations Companies- fund incentive (transaction) based aspects with fees & success sharing 28
  • 29. Akron and Helsinki are “soft landing zones” and Portal Cities to larger markets Akron Helsinki Soft Landing Zone Biomedical Corridor Soft Landing Zone Akron Global Business Accelerator Helsinki Business & Science Park Akron Chamber Viikki Food Center Akron General Culminatum Summa Ministry of Employment & Technology Akron Children’s Greater Helsinki Promotion NEOUCOM VTT U of Akron Biomedicum 1,2,3 Kent State University of Helsinki ABIA Tekes ODOD Sittra ADC Veraventure Angel networks Inventi Others Others Ohio and North Finland and America EU 29
  • 30. AKRON’S FUTURE • TO CONTINUE OUR LEGACY AS A CITY THAT REINVENTS ITSELF • TO ACCELERATE THE TRANSITION TO THE KNOWLEDGE ECONOMY • TO TAKE ADVANTAGE OF ITS FOUNDATION CLUSTERS BY FOCUSING ON BIOMATERIALS,ORTHOPAEDICS, WOUND CARE AND BIOMEDICAL DEVICES • TO CONTINUE TO BE A PLAYER IN THE WORLD ECONOMY • TO ATTRACT WORLD-CLASS TECHNOLOGIES AND TALENT 30
  • 31. What Can We Do To Help? Akron Global Business City of Akron Accelerator Robert Y. Bowman 526 South Main Street Deputy Mayor, Economic Development Akron, Ohio 44311 330-375-2133 Robert E. Anthony Sam DeShazior PH: 330-571-0574 Deputy Planning Director ranth44341@aol.com SDeShazior@AkronOhio.gov www.akronbiomedicalcorridor.com The Akron BioMedical Corridor www.akronaccelerator.com Dr. Zev Gurion www.ci.akron.oh.us Executive Director 330-258-0120 zgurion@akronbiomedicalcorridor.com 31