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Outline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Role of nucleotides ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],5’ 3’
5.27  Similarity and difference RNA-DNA
5.27  Similarity and difference RNA-DNA
5.27  Similarity and difference RNA-DNA
RNA synthesis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ATP+CTP+GTP+UTP (=NTPs)    RNA + PPi (   2Pi) 3’ 5’ 3’ 5’ sense strand template strand Direction of transcription
RNA synthesis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],ATP+CTP+GTP+UTP (=NTPs)    RNA + PPi (   2Pi) 3’ 5’ 3’ 5’ sense strand template strand Direction of transcription
Promotor and TATA-box ,[object Object],[object Object],[object Object],[object Object],[object Object],never never
Promotor and TATA-box ,[object Object],[object Object],[object Object],[object Object],[object Object],never never
[object Object],[object Object],[object Object],[object Object],9  Promoter and terminator in pro- and eukaryote
7  Synthesis of RNA
7  Synthesis of RNA
7  Synthesis of RNA
7  Synthesis of RNA
7:  Elongation of transcription ,[object Object],[object Object],[object Object],[object Object]
Composition of  E. coli  RNA polymerase ,[object Object],[object Object],[object Object],[object Object]
Transcription movie Movies Deze kun je via WebCT bekijken. Neem contact op met de docent als dat problemen geeft.
8:  Initiation of eukaryotic transcription ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
8:  Initiation of eukaryotic transcription ,[object Object],[object Object],[object Object],[object Object]
8:  Initiation of eukaryotic transcription ,[object Object],[object Object],[object Object],[object Object]
Termination of transcription ,[object Object],[object Object],[object Object]
Termination of transcription ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Outline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
9:  Two RNA-processing steps ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],3’UTR= 3’ untranslated region
What is a cap-structure? Essential cell biology, Alberts et al.
What is a cap-structure? Essential cell biology, Alberts et al.
10: Third processing step: splicing ,[object Object],[object Object],[object Object],5’CAP is only one nucleotide,  and Cap belongs to first exon..…

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