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Los Angeles, June 2009




Meaning affects our
  pain experience

  Lorimer Moseley
  NHMRC Senior Research Fellow
  Prince of Wales Medical Research Institute & School of Medical
  Sciences, University of New South Wales, Sydney, Australia


  Team leader
  The GAMFI project
  University of Oxford, UK

                                                             © GL Moseley
                                                   www.BodyInMind.com.au
The context of a noxious Stimulus affects the
pain it evokes
Pain 133, 1-3 64-71




                                            © GL Moseley
                                  www.BodyInMind.com.au
© GL Moseley
www.BodyInMind.com.au
Manipulated meaning of
nociceptive stimulus

-20ºC probe




                                   © GL Moseley
                         www.BodyInMind.com.au
Manipulated meaning of
nociceptive stimulus - HOT

-20ºC probe
                             “hot”




                                         © GL Moseley
                               www.BodyInMind.com.au
Manipulated meaning of
nociceptive stimulus - COLD

-20ºC probe
                              “cold”




                                          © GL Moseley
                                www.BodyInMind.com.au
Very cold (-20ºC) stimulus associated with a red or a blue light



                                          10

                                       Pain

                                          5



                                          0
                                               Red           Blue
                                               light         light
                                                                   © GL Moseley
  Moseley & Arntz 2007 PAIN In press                     www.BodyInMind.com.au
© GL Moseley
www.BodyInMind.com.au
Visual clues that imply more or less danger
change the pain evoked by identical stimuli




                                           © GL Moseley
                                 www.BodyInMind.com.au

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Meaning affects our pain experience