2. Agenda
What is Evidence-Based Public Health? (Indira Gujral)
Brief overview of why it matters
Conducting the Search (Ashley Juhl)
Identifying the search question
Searching the databases
Utilizing the CDPHE Digital Library
Critiquing the Literature (Indira Gujral)
Abstract pertinent information from each document
Organize documents for review
Summarize the scientific literature review
Rating evidence
3. Objective
What will I learn from this training?
How to search for and obtain articles using
the CDPHE Digital Library
How to critique and summarize articles
How to use tools to apply these new skills
Critique Literature
Literature Library
Levels of Evidence to Rate Strategy
4. Using Scientific Literature
Step 1
Step 7 Step 2
Step 6
Step 3
Step 5
Step 4
Materials Located: I:E P EPortfolio Project
6. What is “Evidence?”
Objective
Systematic reviews (Meta-analysis)
Literature from one or more journal articles
Public health surveillance data
Program evaluations
Qualitative data
Community members
Other stakeholders
Media/marketing data
Word of mouth
Personal experience
Slide modified from presentation by Ross Brownson, PhD (2011) Subjective
7. What is “Evidence-based Public Health”?
Institute of Medicine (1988) – public
health is driven by ―crises, hot issues,
and concerns of organized interest
groups‖
Barriers: lack of political will, deficits in research,
resources, leadership, competencies, and deficits in
relevant and timely research
Goal – to improve population health
through widespread adoption of
evidence-based strategies
8. Why use Evidence-Based Strategies?
Higher likelihood of a successful
program
Reduces costs
Impacts the population
Contribute to the body of knowledge
9. Types of Public Health Research Studies
Characteristic Descriptive Research Intervention Research Contextual Conditions
Typical Data/ Size and strength of Relative effectiveness of Information on the adaptation and
Relationship preventable risk—disease public health intervention translation of an effective
relationship (measures of intervention
burden, etiologic research)
Common setting Clinic or controlled community Socially intact groups or Socially intact groups or
setting community-wide community-wide
Example Smoking causes lung cancer Price increases with a Understanding the political
targeted media campaign challenges of price increases
reduce smoking rates
Quantity More (study = 78.5%) Less (study = 14.9%) Even Less
Action Something should be done. This particular intervention How an intervention should be
should be implemented implemented
Slide modified from presentation by Ross Brownson, PhD (2011)
11. Objectives
Learn how to formulate an answerable question for
the literature review (PICO)
Identify search databases
Gain knowledge of resources for grey literature
Learn about the Digital Library project and how to
access full-text journal articles
13. PICO
The acronym PICO can be used to describe this
―answerable‖ question, so that
―P‖= patient problem or population
―I‖ = intervention
―C‖ = comparison intervention
―O‖ = outcome
14. PICO Examples
Problem/ Intervention Comparison Outcome
Population
Unintended School-based sex Abstinence Avoidance of
pregnancy among education education unintended
teens pregnancy
Education in family Consistent
planning clinic contraceptive use
Education in school- Delayed initiation
based health clinics of sexual
intercourse
Community-based All three outcomes
programs
15. Sample Search Questions
For teenagers, will school-based sex education
programs as compared to school-based abstinence
programs decrease unintended pregnancy rates?
Among teenagers, will education in family planning
clinics increase consistent contraceptive use?
Among teenagers, will education in school-based health
clinics delay the initiation of sexual intercourse?
Among teenagers, will education in community-based
health clinics decrease unintended pregnancy rates,
increase consistent contraceptive use, and delay the
initiation of sexual intercourse?
17. What is “Evidence?”
Objective
Systematic reviews (Meta-analysis)
Literature from one or more journal
articles
Public health surveillance data
Program evaluations
Qualitative data
Community members
Other stakeholders
Media/marketing data
Word of mouth
Personal experience
Subjective
Slide modified from presentation by Ross Brownson, PhD (2011)
18. Systematic Reviews
PubMed
http://www.ncbi.nlm.nih.gov/pubmed?holding=codphlib
searches for systematic reviews in biomedical literature
The Cochrane Library
http://www.thecochranelibrary.com/view/0/index.ht
systematic reviews of primary research in human health care and health
policy
free full text from CDPHE computer (through 4/2012)
The Campbell Library
http://www.campbellcollaboration.org/library.php
prepare, maintain and disseminate systematic reviews in education, crime
and justice, and social welfare
free full text
19. What is “Evidence?”
Objective
Systematic reviews (Meta-analysis)
Literature from one or more journal
articles
Public health surveillance data
Program evaluations
Qualitative data
Community members
Other stakeholders
Media/marketing data
Word of mouth
Personal experience
Subjective
Slide modified from presentation by Ross Brownson, PhD (2011)
20. PubMed
Search citations for biomedical literature from MEDLINE, life
science journals, and online books
Clinical Queries will locate clinical studies, systematic
reviews, and medical genetics citations
MeSH Database will help pinpoint concepts
ClinicalTrials.gov will locate clinical trial information and
results
http://www.ncbi.nlm.nih.gov/pubmed?holding=codphlib
21. My NCBI
Save searches and records
Automatic email alerts
Filter search results by subject
Free
http://www.ncbi.nlm.nih.gov/sites/myncbi/
22. PubMed Search
For teenagers, will school-based sex education
programs as compared to school-based abstinence
programs decrease unintended pregnancy rates?
teenagers
school-based sex education
school-based abstinence education
unintended pregnancy
23. What is “Evidence?”
Objective
Systematic reviews (Meta-analysis)
Literature from one or more journal
articles
Public health surveillance data
Program evaluations
Qualitative data
Community members
Other stakeholders
Media/marketing data
Word of mouth
Personal experience
Subjective
Slide modified from presentation by Ross Brownson, PhD (2011)
24. Types of Grey Literature
conference papers/posters/abstracts
official documents and white papers
reports and proceedings
theses and dissertations
official documents
informal communications
research in progress reports
registered clinical trials
25. Grey Literature
NOT controlled by commercial publishers
Often includes information vital to research –
especially public health
NOT indexed in major databases, including
PubMed
More current than published material
26. Grey Literature Sources
Specialized search engines
New York Academy of Medicine Grey Literature Report
Science.gov
Scirus
Google Scholar
Promising Practices
Institutional repositories, scientists websites
28. Problem
State and local public health lack sufficient access
to databases, full-text journal articles, and books
Individual/program subscriptions
University access through students/faculty
Impedes ability to find best available evidence to
improve health
29. Digital Library Project
Purpose: To better understand the usefulness of
providing public health departments with access to
selected licensed e-resources (databases, books,
journal articles)
Funder: National Network of Libraries of Medicine,
New England Region
CDPHE Lead: Dr. Lisa Miller (Director, DCEED)
Funding through April 2012
CDPHE Digital Library launched in January 2011
30. Project Objectives
Promote selected e-journals and two databases
that contain evidence-based public health resources
(in addition to PubMed):
Stat!Ref– compilation of full-text E-books
Global Health—contains public health information
back to 1912
License EndNote for multiple users
Provide subsidized Interlibrary Loan to those who
work in the selected public health departments
32. Digital Library Contents
Colorado specific PubMed link
Access to Cochrane Library, STAT!Ref and Global
Health
Links to 55 e-journals with free full-text
Free journal article delivery service
Poudre Valley Health System Medical Library
Other databases, academic, and government
websites
33. Access to Journal Article Delivery Service
Access to LoansomeDoc will be provided by Poudre
Valley Health System
Library of first resort
Registration to LoansomeDoc to monitor usage
https://docline.gov/loansome/login.cfm
Free service, easy to use
Utilize University of Massachusetts Lamar Soutter
Library
Library of last resort
34. Requesting Journal Articles for Delivery
PubMed
Select send to – order - order articles
Sign in to LoansomeDoc
Request article even if not in holdings (ignore cost box)
Other sources
Email Jerry Carlson directly gmc@pvhs.org
Include all article information
Articles will be e-mailed to requestor directly at no
charge
35. Requesting Journal Articles for Delivery
Continued
Before submitting request, make sure the journal is
not listed in the ―E-Journals‖ section of the Digital
Library page
Immediate retrieval of article (access to free full-text
from a CDPHE computer)
39. Abstracting Information
Critique an Article
Critique: ―an act of criticizing‖
Merriam Webster
Key Elements:
Balanced
Includes strengths and weaknesses
Constructive
Providing suggestions for how the study might be
improved
40. What will I be Critiquing?
Objective
Systematic reviews (Meta-analysis)
Literature from one or more journal articles
Public health surveillance data
Program evaluations
Qualitative data
Community members
Other stakeholders
Media/marketing data
Word of mouth
Personal experience
Subjective
Slide modified from presentation by Ross Brownson, PhD (2011)
41. How to Critique an Article (Handout)
1. Source
* Is the report from a peer reviewed publication?
* Is the research current?
2. Research Problem
* Is the problem identified clearly?
* Is it significant--does the researcher provide a good
argument for significance?
42. How to Critique an Article
3. Literature Review
* Is it convincing that the author reviewed a sufficient
amount of literature? (More than one source?)
* Is it balanced, presenting literature that supports
and that differs from the researcher's position?
* Is the review written critically (giving strengths and
weaknesses of previous work)?
* Are references current, or a combination of current
and classic?
43. How to Critique an Article
4. Theoretical Framework
* Is a theoretical framework specified?
* Does the framework "fit" the problem? Include all
relevant variables?
* Are results interpreted in reference to the
theoretical framework?
--Note: qualitative research, descriptive studies, and
physiologic studies typically will not have a
theoretical framework.
44. How to Critique an Article
5. Variables
* Are the variables in the study appropriate to the problem?
* Are the means to measure the variables appropriate?
6. Hypotheses
* Are hypotheses stated? If not, does the researcher provide
sufficient information to determine what the hypotheses
were?
* If stated, are the hypotheses clear? Specific? Testable?
--Note: qualitative research and many types of descriptive
studies do not involve hypotheses. In a qualitative study the
researcher may suggest hypotheses as a result of the
research.
45. How to Critique an Article
7. Design (overall)
* Is the design specified correctly?
* What design was used?
* Is the design appropriate to answer the research
question?
* Did the researcher attempt to control for threats to
internal and external validity?
46. How to Critique an Article
8. Sample
* Is the sample size adequate?
* Is the sample likely to be similar to members of the
appropriate population overall?
* Are the criteria for including and/or excluding
people or items from the sample clear and
appropriate?
47. How to Critique an Article
9. Data Collection
* Are the instruments or other means for data
collection described sufficiently?
* Are reliability and validity of instruments
addressed? Are these adequate?
* Are data collection methods described clearly?
* Are the data collection methods appropriate?
* Could the researcher have affected the results of
the study in some way related to the collection of
data?
48. How to Critique an Article
10. Data Analysis
* Is the process used to analyze data clear?
* Were the processes for data analysis appropriate to answer the research
question?
* Do the results provide an answer to the research question?
* If tables are provided, are these clear and understandable?
For qualitative studies, some additional items for critique include:
* Does the researcher provide sufficient examples of the data (for
example, passages or quotations from interviews) to support the
identified results?
* Does the researcher describe processes that were used to avoid biasing
or influencing the data obtained and the analysis procedures used? (Ex.
Peer review, logs, memos, "member check―)
49. How to Critique an Article
11. Discussion and Interpretation of Findings
* Does the discussion "fit" with the data? Is it logical based on
the data and results presented?
* Does the researcher discuss the findings in regard to previous
research?
* Does the researcher discuss the findings in regard to the
theoretical framework?
* Does the researcher identify limitations of the study? How do
these affect the quality of the study?
* Does the researcher discuss implications for practice? Are
these appropriate?
50. How to Critique an Article
12. Ethical Considerations
* Does the researcher indicate that approval was obtained
from appropriate review boards?
* Were the rights of human subjects protected (confidentiality)?
13. Application to Public Health
* How similar are the conditions of the study (setting, sample,
interventions, etc.) to our setting?
* How feasible would it be to make a change in practice based
on this research?
52. Organizing Documents for Review
TIPS FOR KEEPING YOURSELF
SANE….AND ORGANIZED!
Organize by publication type (review articles,
government/agency guidelines, original research)
Enter information into reference management
database (EndNote, Reference Manager, ProCite)
Store articles in a file drawer in alphabetical order
by author’s name
Keep your literature summaries organized
electronically (Xcel, Access, Word)
53. Literature Library
Literature Library
• Xcel Sheet with all of the pertinent information
• More information than an abstract
• Critical for sustaining work over time (i.e.
childhood obesity)
• Materials Located: I:E P EPortfolio Project
54. Literature Library
Title: Managed Care and School-Based Health Centers
Authors: Kaplan, DW Archives of Pediatric Medicine 1998
Study Design: Retrospective cohort
Study Population: Adolescent members of Kaiser Permanente 342 adequate Records Review
Chi-Squares presented
Results: Adolescents with access to SBHCs were more than 10 times more likely to make a mental health or substance
abuse visit (98% of these visits were made at the SBHC) (P,.001). Adolescents with SBHC access had an after-hours
(emergent or urgent) care visit rate of 0.33 to 0.52 visits per year less (38%-55% fewer visits) than adolescents without
SBHC access, and, overall, made almost 1 additional medical visit per year. A greater percentage,
80.2%, of adolescents with access to SBHCs had at least 1 comprehensive health supervision visit compared with 68.8%
of adolescents without access (P=.04). In addition, the adolescents with access were screened for high-risk behaviors at a
higher rate. School-based health centers seem to have a synergistic effect for adolescents enrolled in managed care in
providing comprehensive health supervision and primary health and mental health care and in reducing after-hours
(emergent or urgent) visits.
Conclusion: School-based health centers are particularly successful in improving access to and
treatment for mental health problems and substance abuse.
Notes: old article but everyone cites this Managed Care and School-Based Health Centers
57. Public Health Evidence Rating (Handout)
How Established Considerations for Level of Scientific Data Source Examples
Evidence
Proven Peer review via systematic or Based on study design and execution Community Guide
narrative review External validity Cochrane reviews
Potential side benefits or harms Narrative reviews based on published
Costs and cost-effectiveness literature
Likely Effective Peer Review Based on study design and execution Articles in the scientific literature
External validity Research-tested intervention programs
Potential side benefits or harms Technical reports with peer review
Costs and cost-effectiveness
Promising Written program evaluation Summative evidence of effectiveness State or federal government reports
without formal peer review Formative evaluation data (without peer review)
Theory-consistent, plausible, potentially Conference presentations
high-reach, low-cost, replicable
Emerging Ongoing work, practice-based Formative evaluation data Evaluability assessments*
summaries, or evaluation works in Theory-consistent, plausible, potentially Pilot studies
progress high-reaching, low-cost, replicable National Institute of Health (NIH)
Face validity research
(RePORT database)
Projects funded by health foundations
Not Recommended Varies. Evidence of effectiveness is conflicting Varies.
and/or of poor quality.
Weak theoretical foundation
Balance of benefit and harm cannot be
established or evidence demonstrates that
harm outweighs the benefits.
* A pre-evaluation activity that involves an assessment to establish whether or program or policy can be evaluated, what the
barriers to its evaluation might be.
Source: Adapted from Healthy People 2020 and Brownson RC, Fielding JE, Maylahn CM. Evidence-based Public Health: A
Fundamental Concept for Public Health Practices . Annual Review of Public Health. Vol. 30: 175-201