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The Appliations of Vitamin D5 and
Other Four Chemicals
-Chemical Study Material
Vitamin D5
• Vitamin D5, a member of the family Vitamin D
which was discovered by Edward Mellanby in
1919 during his classic experiments with rickets,
is about 180-fold less active than vitamin D3, in
calcification of rachitic cartilage and about 100-
to 200-fold less active in induction of bone
calcium mobilization. In stimulation of intestinal-
calcium transport, vitamin D5 is about 80 fold less
active than vitamin D3.
• http://www.bocsci.com/vitamin-d5-cas-71761-
06-3-item-453668.html
BI605906
• BI605906, also called SCHEMBL4470165, is a novel
pharmacological inhibitor of TNFα-dependent IκB
degradation. In additonally, it also inhits expression of
pro-inflammatory mediators IL-6, IL-1b, and CXCL1/2.
IKKβ: IC50= 380 nM (when assayed at 0.1 mM ATP) In
vitro: BI605906 not only prevents the phosphorylation
of physiological substrates, such as p105 and RelA, but
also the phosphorylation of the serine residues in IKKβ
(Ser177 and Ser181) that trigger its activation.
• http://www.bocsci.com/bi605906-cas-960293-88-3-
item-461018.html
2'-DEOXY-2'-FLUORO-5-IODOCYTIDINE
• 2'-DEOXY-2'-FLUORO-5-IODOCYTIDINE, also called
AC1NQP33, SCHEMBL138935, under the IUPAC name
4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-
(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one;
80791-93-1, is a potent anti-​hepatitis C virus (HCV)
agent.Several 2'-deoxy-​2'-
halogenoarabinofuranosylcytosines and -uracils
substituted at C-​5 of the aglycon with Br or I were
prepd. and evaluated for antiherpetic activity against
both herpes virus type 1 and 2 on monolayers of Vero
cells by the plaque redn. assay.
• http://www.bocsci.com/2-deoxy-2-fluoro-5-
iodocytidine-cas-80791-93-1-item-242021.html
Ecamsule
• Ecamsule protect the skin from sunburn and
erythema. It causes serious eye damage, so
please wear protective gloves/protective
clothing/eye protection/face protection.
• Sunscreening Agents
• http://www.bocsci.com/ecamsule-cas-92761-
26-7-item-158386.html
6-Carboxytetramethylrhodamine
• 6-carboxy derivatives of tetramethylrhodamine is
one of the most convenient compounds of
Xanthene fluorescent dye tetramethylrhodamine.
6-Carboxytetramethylrhodamine is a long-
wavelength dye. Besides that, it also can be used
for labeling of biomolecules.
• http://www.bocsci.com/6-
carboxytetramethylrhodamine-cas-91809-67-5-
item-100558.html

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The appliations of vitamin d5 and four other chemicals

  • 1. The Appliations of Vitamin D5 and Other Four Chemicals -Chemical Study Material
  • 2. Vitamin D5 • Vitamin D5, a member of the family Vitamin D which was discovered by Edward Mellanby in 1919 during his classic experiments with rickets, is about 180-fold less active than vitamin D3, in calcification of rachitic cartilage and about 100- to 200-fold less active in induction of bone calcium mobilization. In stimulation of intestinal- calcium transport, vitamin D5 is about 80 fold less active than vitamin D3. • http://www.bocsci.com/vitamin-d5-cas-71761- 06-3-item-453668.html
  • 3. BI605906 • BI605906, also called SCHEMBL4470165, is a novel pharmacological inhibitor of TNFα-dependent IκB degradation. In additonally, it also inhits expression of pro-inflammatory mediators IL-6, IL-1b, and CXCL1/2. IKKβ: IC50= 380 nM (when assayed at 0.1 mM ATP) In vitro: BI605906 not only prevents the phosphorylation of physiological substrates, such as p105 and RelA, but also the phosphorylation of the serine residues in IKKβ (Ser177 and Ser181) that trigger its activation. • http://www.bocsci.com/bi605906-cas-960293-88-3- item-461018.html
  • 4. 2'-DEOXY-2'-FLUORO-5-IODOCYTIDINE • 2'-DEOXY-2'-FLUORO-5-IODOCYTIDINE, also called AC1NQP33, SCHEMBL138935, under the IUPAC name 4-amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5- (hydroxymethyl)oxolan-2-yl]-5-iodopyrimidin-2-one; 80791-93-1, is a potent anti-​hepatitis C virus (HCV) agent.Several 2'-deoxy-​2'- halogenoarabinofuranosylcytosines and -uracils substituted at C-​5 of the aglycon with Br or I were prepd. and evaluated for antiherpetic activity against both herpes virus type 1 and 2 on monolayers of Vero cells by the plaque redn. assay. • http://www.bocsci.com/2-deoxy-2-fluoro-5- iodocytidine-cas-80791-93-1-item-242021.html
  • 5. Ecamsule • Ecamsule protect the skin from sunburn and erythema. It causes serious eye damage, so please wear protective gloves/protective clothing/eye protection/face protection. • Sunscreening Agents • http://www.bocsci.com/ecamsule-cas-92761- 26-7-item-158386.html
  • 6. 6-Carboxytetramethylrhodamine • 6-carboxy derivatives of tetramethylrhodamine is one of the most convenient compounds of Xanthene fluorescent dye tetramethylrhodamine. 6-Carboxytetramethylrhodamine is a long- wavelength dye. Besides that, it also can be used for labeling of biomolecules. • http://www.bocsci.com/6- carboxytetramethylrhodamine-cas-91809-67-5- item-100558.html