Desh bandhu gangwar antisense technology

ANTISENSE TECHNOLOGY Presented By Desh Bandhu Gangwar M.Tech Biotech (2 year) Concerned Faculty Dr. Gunjan Garg Assistant Professor School of Biotechnology

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Antisense Oligonucleotides ,[object Object]

Mechanism of antisense activity

Types Of AS-ON ,[object Object],[object Object],[object Object]

A successful AS-ON depends on the following characteristics : ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

First generation AS-ON ,[object Object],[object Object]

Sites of chemical modification

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Second generation AS-ON ,[object Object],[object Object]

Characterstics of second generation AS-ON ,[object Object],[object Object],[object Object],[object Object]

Third generation AS-ON ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Peptide nucleic acids ,[object Object],[object Object],[object Object]

Locked nucleic acid ,[object Object],[object Object]

Ribozymes ,[object Object],[object Object],[object Object]

Types Of Ribozymes ,[object Object],[object Object],[object Object],[object Object],[object Object]

Cycle of RNA cleavage by hammerhead ribozyme

Ribozymes in clinical trials ,[object Object],[object Object],[object Object]

RNA interference ,[object Object],[object Object],[object Object]

Comparision Of different Antisense stratgies

Applications Of Antisense technologies ,[object Object]

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REFERENCE ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Desh bandhu gangwar antisense technology

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