Glomerular Filtration and determinants of glomerular filtration .pptx
Tom steele 1
1. Every Child Counts
iLearn, iGrow, iSucc
eed
ACSA Symposium
2014
Los Angeles County Office of Education
Division of Student Support Services
Community Health & Safe Schools Unit
2. DISCLAIMER
Information contained in presentation and
materials are for information purposes only, and
may not apply to your situation. Information
provided is subjective. The author, presenter and
Los Angeles County Office of Education provide
no warranty about content or accuracy of content
and assume no liability for any action or reaction
arising from use of the information. Medical
personnel and/or law enforcement should be
contacted if use of substance is suspected to
insure proper diagnosis and treatment. All links
are for information purposes only and are not
warranted for content, accuracy, or any other
implied or explicit purpose.
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3. MYTHS & MISCONCEPTIONS
Beliefs about teen drug
and alcohol use
• Teen drinking, drug use
is no big deal
• They are just
experimenting
• I would know if my
students are using
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4. DEFINITIONS
DRUGS – substance that
causes physical or
emotional change
• Alcohol, illegal
drugs, tobacco, herbal,
caffeine, inhalants
• Over-the-counter (nonprescription)
• Prescription (doctor
written order)
PSYCHOACTIVE
EFFECTS – effects of a
person’s mood or
behavior
• Mood-altering
• Affects brain activity
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5. DEFINITIONS
• Addiction: body relies on given drug to help it function
• Compulsive use of drug- despite cost
• Changes structure and chemistry of brain
• Tolerance: need increased amount to feel effects
• Craving: strong need for drug, can’t manage without it
• Loss of Control: preoccupied with drug or alcohol and
unable to limit use
• Physical Dependence: experience withdrawal, may
include death, coma, muscle
trembling, disorientation, sweats, insomnia
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6. CENTRAL NERVOUS SYSTEM
(CNS) STIMULANTS
Includes:
Nicotine
Speed up mental and physical
responses of CNS
Cocaine
• Enhances brain activity
Methamphetamine
• Causes increase in
alertness, attention and
energy
• Increases blood
pressure, heart rate and
breathing
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7. COCAINE
• Cocaine HCL (Powder), Cocaine
Base (Crack)
• Grows primarily in Peru and Bolivia
• Not Columbia!
• First extracted in mid-19th century
• Used as tonic/elixir to treat variety
of illnesses, and as local anesthetic
• Continues to have limited use in
surgery
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8. METHAMPHETAMINE
• Powder, Rock (ICE)
• Amphetamine has close chemical relations to
methamphetamine and dextroamphetamine
• CNS stimulants whose reactions resemble those of
adrenaline
• Amphetamine was used in 1930’s for nasal congestion
(pseudoephedrine today)
• Was created by German chemists in WWII in attempt
to create a SUPER SOLDIER
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9. CNS STIMULANT: HEALTH HAZARDS
• Feelings of
restlessness, irritability and
anxiety
• Prolonged use can trigger
paranoia
• Depression when addicted
individuals stop using
• Deaths often a result of
cardiac arrest or seizures
followed by respiratory arrest
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10. CNS DEPRESSANTS
Includes:
Alcohol
Marijuana
Opioids such as
Heroin, OxyContin,
Codeine, Vicodin,
Morphine
Slow down mental and physical
responses of CNS
• Slows down brain
functions, breathing
rates, blood pressure and
body reactions
• In higher doses, some CNS
depressants can become
general anesthetics
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11. OPIATES
• Called narcotics
• Powerful painkillers with high potential for abuse
& addiction
• Prescribed for pain relief
• Attach to receptors in brain, spinal cord and
gastrointestinal tract
• Affect part of brain that perceives
pleasure, causing initial euphoria
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12. HEROIN
• Name for illicit opiate
• Morphine=prescription
• 1874, created from opium
poppy
• 2004, Afghanistan produced
roughly 87% of world supply
• Mexico is second largest
producer in world
• Cartels produce black tar heroin
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13. CNS DEPRESSANT: HEALTH HAZARDS
• Tolerance develops
• Physical dependence, addiction
• Produces drug craving, restlessness, muscle
and bone
pain, insomnia, diarrhea, vomiting, cold
flashes, kicking movements
• Withdrawal
• Symptoms occur if use is reduced
• May occur within hours after last use
• Sudden withdrawal is occasionally fatal
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15. MDMA, ECSTASY, E
• Synthetic, psychoactive drug with both
stimulant and hallucinogen properties
• Created in 1914, produced for black
market in 1970s
• Taken orally (most common), can be
snorted or injected
• Usually pill form, variety of colors, shapes
and symbols
• Can be powder or capsules
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16. LSD, ACID
• Generic name for Lysergic
Acid Diethylamide-25
• One of most potent mindaltering chemicals known
• Usually taken orally (on
candy, sugar cubes, blotter
paper or liquid directly on
tongue)
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17. HALLUCINOGENS: HEALTH HAZARDS
• Similar to cocaine
• Psychological difficulties:
confusion, depression, sleep problems, severe
anxiety and paranoia
• Physical problems: muscle tension, involuntary teeth
clenching, nausea, blurred vision, faintness, chills
and/or sweating
• Damages parts of brain crucial to processes of
thought, memory and pleasure
• Not considered addictive, but produces a tolerance
• Hallucinations and Flashbacks
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18. INHALANTS
• Breathable chemical vapors that
produce psychoactive effects
• In common household products;
paint, glue and cleaning fluids
• Children and adolescents can
easily obtain and are among
most likely to abuse these
substances
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19. INHALANTS: HEALTH HAZARDS
• Chronic abuse causes severe, long-term damage
to brain, liver and kidneys
• Hearing loss
• Limb spasms
• Bone marrow damage
• Blood oxygen depletion
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20. IF YOU SAW THESE…
…would you be worried?
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21. BATH SALTS AND SPICE/K2
• Synthetic drugs (designer drugs), mimic active
ingredient in marijuana (THC)
• First appeared in 2004 in U.S.
• Sold in head shops, convenience stores and online
• Can be smoked, injected, snorted, or mixed with
food and drink
• Many of compounds found in synthetic drugs have
now been banned, making them illegal
• Substances do not show up on conventional drug
screening tests
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22. • Hallucinogen and depressant
MARIJUANA
• Contains THC, (delta-9tetrahydrocannabinol) main active
chemical
• THC content has increased six fold
since 1978
• Contains more than 400 other
chemicals
• Usually smoked: joint, pipe, bong
• Can be eaten
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23. MARIJUANA: HEALTH HAZARDS
• 1 in 6 become addicted
• THC damages cells that protect against disease
• Causes cancer, lung and airway problems
• Associated with onset of psychotic symptoms
• Teen use causes permanent damage to part of brain
responsible for executive function
• Planning, abstract thinking, understanding rules, inhibiting
inappropriate actions and measuring cognitive flexibility
• Decreases activity in working memory areas of
brain, delaying reaction and ability to remember
accurately
• Impairs motivation
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24. MEDICAL USE OF MARIJUANA
• Prescription THC is manufactured in pill
form, Marinol, and has been available for over 30
years
• Studies show medical marijuana is less effective
than traditional medicines and has more side
effects
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25. MEDICAL MARIJUANA IN SCHOOLS
• Law does not allow possession or
use of marijuana, including
medical marijuana
• Students may be disciplined for
being under influence of or
possession of marijuana
• Medical marijuana may not be smoked: where smoking
is prohibited by law; within 1,000 feet of school; on
school bus; or in moving motor vehicle or boat H&S11362.79
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26. MEDICAL MARIJUANA
IN SCHOOLS
• Student medication use during school day must have
prescription from California physician EC 49423
• Physicians may not prescribe marijuana
• only give recommendation H&S 11362.5
• If student’s health condition is so serious that it
requires administration of marijuana, then student
may be too sick for school
Los Angeles County Office of Education
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27. OVER THE COUNTER DRUGS (OTC)
AND PRESCRIPTION MEDICATIONS
• OTC: cough/cold/congestion with
‘DXM’ (Robitussin, Coricidin)
known as “triple C”
• Prescription Medications
• CNS Stimulants: Ritalin, Adderall
(amphetamine based)
• CNS Depressants:
Valium, Librium, Xanax, Morphine, C
odeine, Oxycontin, Vicodin, Demerol
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28. • Curiosity
WHY DO KIDS USE DRUGS?
• Boredom
• Feel good
• Pleasure
• Relax
• Forget troubles
• Feel grown up
• Show independence
• Peer pressure
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29. RISK FACTORS
• Disabilities, such as ADD/ADHD - self
medicated
• Failing in school
• Victim of bullying, cyberbullying
• Experiencing low self-esteem
• Living with addicted family member or
community with high tolerance for use
• Internet accessible substances
• TV: Jersey Shore, Teen Mom, Gossip
Girl, etc.
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30. SIGNS OF USE
• Change in relationships with family and friends
• Loss of inhibitions, mood changes, instability
• Depressed, unable to
focus, hostile, angry, uncooperative, deceitful, se
cretive
• Decreased motivation, lethargic
• Sleeplessness, hyperactivity
• Personal appearance, health issues
• Grades dropping, truancy, work-related issues
• Lying and stealing – stories don’t add up
• Paraphernalia, clothing, jewelry
Sometimes it’s hard to tell if it’s just “normal” teen behavior
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31. I KNOW STUDENT IS USING
• What is your evidence?
• Consult with peer, administrator
• Conversation (not a confrontation) is critical to help
• Expect denial and anger
• Find ways to break through barriers
• Don’t just talk, listen
• Spell out rules and consequences
• Remind student of your support
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32. DRUG TESTING
• Does not detect every possible drug
• Helps reduce peer pressure
• Trust your instincts
• "radar" often accurate; do not ignore “gut
feelings”
• Recommend consult family doctor, counseling
• Plan how to react when drug use discovered
• There are underlying reasons for drug
use, reasons need to be discovered and “dealt
with”
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33. EDUCATE FAMILIES
• Safeguard prescription, OTC drugs
and alcohol
• 39% of teens who abuse prescription
drugs get them from family member’s
or friend’s medicine cabinet
• Dispose of medicines properly
What’s in
your cabinet
at home?
• Ask family - grandparents, &
friends to be alert and safeguard
drugs and alcohol
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34. FAMILY PROTECTIVE FACTORS
• Parents talk to child about drugs/alcohol at young age
• Use teachable moments
• Listen, make it easy for child to talk honestly
• 50% less likely to use, if learn about risks of drugs at home
• Open communication
• not lecturing, no “he said/she said” conversations
• Provide rules that are clear and consistent with
consequences
• Be a good role model (grandparents, uncle, aunt)
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35. TIPS FOR PARENTS TO KEEP CHILD SAFE
•
•
•
•
•
You condone what you ignore
Be involved in your child’s activities
Plan family activities at least 3+ times a month
Know your child’s friends and their parents
Children want freedom, it needs to be earned and it’s
not appropriate with substance use
• IT IS OKAY TO SNOOP, parents can decide to look
through their child’s room and belongings
• Monitor whereabouts and technology use
(eblaster.com, etc.)
• Trust, but verify
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36. DON’T
• React with anger, even when shocked
• Ridicule
• Give consequences that you will not
follow through
• Expect every conversation to be
perfect
• Simply demand, instead educate
about risk
• Make stuff up, if you don’t
know, look it up or help them look it
up
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37. RESOURCES FOR HELP
• Bill Cosby-Fatherhood-a must read for every parent
• AA, Marijuana or Narcotics Anonymous
• Treatment centers
• www.findtreatment.samhsa.gov
• www.drugstrategies.org
• http://findtreatment.samhsa.gov/facilitylocatordoc.htm
• National Institute on Drug Abuse – http://www.nida.nih.gov
• NIDA for Teens – http://www.teens.drugabuse.gov
• Partnership for a Drug Free America – http://www.drugfree.org
• CA Narcotic Officer’s Assoc. – http://cnoa.org/home/nefa/
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Even first-time use can lead to accidents, injury, and deathTeens put a great deal of energy into concealing drug and alcohol use. From gum (to mask breath) to specially-bought containers that look like household items,to conceal drugs, kids are how to hide drug use
Marijuana smoking frequently starts inearly teens. Study by Dr. Staci A. Gruber, Director of Cognitive and Clinical Neuroimaging at McLean Hospital, a Harvard-affiliated hospital in Belmont, Massachusetts, used brain scans and had subjects complete an assessment of executive function. Executive function is brain processes responsible for planning and abstract thinking as well as understanding rules and inhibiting inappropriate actions and measuring cognitive flexibility. Part of brain that modulates executive function is last part of brain to develop. Dr. Gruber’s study found that marijuana use in adolescence causes permanent damage. It is widely known that marijuana use impairs motivation. It is associated with lowering of psychotic symptoms. Marijuana use and relationship to schizophrenia are being studied. Recently published research in the Journal of Biological Psychiatry explores impact that cannabis use has on working memory. Study gave healthy subjects tetrahydrocannabinol (THC) or a placebo and then gave test for working memory that involveduse of short-term memory storage and manipulation of memory. Subjects receiving THC had decreased activity in areas of brain that are associated with working memory, significantly retarded activity in prefrontal cortex. Subjects given THC also exhibited lengthened reaction time and degraded accuracy of recall. Bossong MG, et al., “Effects of ^9-tetrahydrocannabinol in human working memory function,” Biol Psychiatry, 2012 April 15; 71: 693-699.
H&S 11362.79 Locations prohibited to smoke marijuana
H&S 11362.5 physician can recommend
May include behavioral issues – especially challenging or difficult behavior; changes in personal appearance, habits, and health issues; are they having problems at school or work?Look for multiple changes, or suddenness of changes. Trust your instincts, and be aware of risk factors
Sit down, relax, and take time to breathe, then: Talk with peer (if you will be speaking to teen as a team) and present a united front Prepare to be called a hypocrite – Teen may challenge you about your past use. Don’t get diverted – issue here and now is their use, their health, and their safety. It’s not about your past – it’s about their future. Gather any evidence – Prior to having conversation, identify specific reasons why you think they are using. Expect denial and possible anger: Most important thing is to keep conversation going. Resolve to remain calm, no matter what teen says -- Try not to be baited to respond with anger. Set an expected outcome -- Your conversation will go more smoothly if you have a desirable outcome in mind. A reasonable objective, like simply expressing that you don't want use, can be atriumph. Spell out rules and consequences -- Have rules and idea of consequences set going in. Listen to teen's feedback and let themhelp negotiate rules and consequences. Don't set rules you will have no way of enforcing. Recognize significance of addiction in family – If a history of addiction - cocaine, alcohol, nicotine, etc. – is in family, then teen has much greater risk of developing an addiction. You need to be aware elevated risk and discuss it with teen as you would any disease. Remind teen of support -- Speak from a place of caring and concern - and express these feelings. Explain reason you're talking with them and asking questions is because you careand want them to be healthy and successful.
In 2002, by a margin of 5 to 4, U.S. Supreme Court, in Board of Education of Pottawatomie v. Earls, permitted public school districts to drug test students participating in competitive, extracurricular activitiesCSBA Board Policy BP 5131.61 – Drug Testing. Drug testing program which may be allowed under federal law may nevertheless violate California law, if district does not have a compelling reason for drug testing students.California case questions whether district’s drug testing program can be extended beyond athletics without some compelling justification.In unpublished California case, Court of Appeal upheld a preliminary injunction against a district’s drug testing program which required students who participated in certain competitive, nonathletic extracurricular activities to be subject to random, suspicion-less drug tests. Court analyzed district’s policy under Article 1, Section 1 of California Constitution which provides more individual privacy protection than U.S. Constitution. While safety of students participating in athletics is recognized as justification for drug testing athletes, districts will need to show evidence of drug use or other justification for testing students in other contexts such as extracurricular activities. It is recommended that districts consult legal counsel prior to adopting student drug testing policy or procedures.
Dispose of unused or expired medications properly. They can pollute environment. DEA and law enforcement have drop-off locations. If you just throw them out, some people will go through garbage to get them.
Kids want freedom, giving them freedom they can handle is good, but if drugs and alcohol are involved, all bets are offRules provide concrete way to help kids understand what is expected and learn self–control. Don't just assume they "know" not to drink or do drugs. Teens don't deal well with gray areas, so when offered alcohol or drugs, you don't want any confusion in their minds.For rules to matter, they must be enforced. Be consistent, and make consequence appropriate to rule that has been broken.
Some situations require teen to enter a treatment facility, don't be put off by term "get help." Connect them with caring adults – especially someone your teen already knows and trusts; school counselors, family doctor,sports team coach, clergy; or counselors at treatment center.Drug addiction affects more people than just the addict. The family, especially non–drug–using teens need help to make sure that they are emotionally stable and fully comprehend situation, you're aiding in everyone's recovery and healing process.Many parents lose ability to think and act rationally when they have a teenin danger. Some parents become so obsessed with their child and her problem that they neglect other important aspects of their own lives: their jobs, physical health, and other kids., it is vital that they have help for their own emotional well-being.