1) Life expectancy is often misunderstood and misused in clinical practice, as it does not guarantee how long a particular patient will live and is actually a median, not a mean or individual prediction. 2) Clinician estimates of patient life expectancy tend to be overly optimistic and inaccurate compared to statistical models. 3) The document recommends using models built on clinical data that adjust life expectancy based on early mortality risks and comorbidities, such as the MSKCC nomogram, rather than relying solely on clinician guesses.