This document summarizes several genetic syndromes associated with an increased risk of colorectal cancer, including Lynch syndrome, familial adenomatous polyposis (FAP), MYH-associated polyposis, Peutz-Jeghers syndrome, and juvenile polyposis syndrome. It describes the characteristic features, inheritance patterns, cancer risks, and genes involved for each syndrome. Technological advances in genetic sequencing methods are making the identification of causal gene mutations more efficient.