The document provides an overview of the ISIS synchrotron, including its operation, components, and challenges. Key points: - ISIS accelerates proton beams from 70 MeV to 800 MeV using repeated low-voltage RF acceleration over thousands of turns in a circular ring. - Focusing quadrupole magnets are used to maintain the transverse beam size and stability. Injection and extraction systems introduce and remove beams from the ring. - Operating a high-intensity machine like ISIS presents challenges in tightly controlling fractional beam losses to minimize activation and prevent damage.