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Headache



                Fayza Rayes
                MBBCh. Msc. MRCGP
             Consultant Family Physician
Joint Program of Family & Community Medicine, Jeddah
             www.fayzarayes.com
:Contents

1.   Approach to patient with headache

2.   Migraine

3.   Tension headache
An Approach to the Headache History


1. How many different headache types
does the patient experience?


  (Separate histories are necessary for each)
An Approach to the Headache History
2. Time questions
a) Why now?
b) How recent in onset?
c) How frequent
d) What pattern (temporal distribution)
d) How long lasting?
3. Character questions
a) Intensity of pain?
b) Nature and quality of pain?
c) Site and spread of pain?
d) Associated symptoms?
Temporal distribution of different
  types of headache with time

Migraine

Tension headache
Migraine + Tension
(combination)
Cluster headache

Raised intracranial
pressure
.Headache DD
An Approach to the Headache History

4. Cause questions
a) Predisposing and/or trigger factors?
b) Aggravating and/or relieving factors?
c) Family history of similar headache?

5. Response to headache questions
a) What does the patient do during the headache?
b) Function limited or prevented?
c) Medication
An Approach to the Headache History


 6. State of health between attacks
 a) Completely well, or residual or persisting
 symptoms?
 b) Concerns, anxieties, fears about recurrent
 attacks and/or their cause?


Source: Steiner TJ, MacGregor EA, Davies PTG. Guidelines for All Healthcare Professionals
in the Diagnosis and Management of Migraine, Tension-Type, Cluster
and Medication Overuse Headache (3rd edition, 2007). www.bash.org.uk
Headache History
   1st Consultation
Diary Card …what for
 Confirm the diagnosis
 Assess frequency and duration of the
  attacks
 Assess response to treatment
 Identify potential triggers
 Involve patient in the managment
App. Headache diary
Headache diary: episodic headaches

                              It shows
                              episodic
                              headache
                              with complete
                              freedom from
                              symptoms
                              between
                              attacks,
                              confirming the
                              diagnosis of
                              migraine with
                              and without
                              aura
Headache diary: daily headaches



                             Possible
                             medication
                             overuse)
                             with
                             migraine
Headache diary:
daily headaches (possible medication overuse) with migraine
Episodic Headache & Chronic Headache
The mnemonic “SNOOP” as a reminder of the red
flags that may point to the potential of a more
serious, secondary headache
Headache History
   2nd Consultation
Headache Physical Examination
   The examination must be thorough but can be brief.
   Examine the head and neck for muscle tenderness ,
    stiffness, limitation in range of movement and
    crepitation.
   Funduscopic examination is mandatory at first
    presentation with headache, and it is always worthwhile
    to repeat it during follow-up.
   Blood pressure measurement
   A quick neurological examination may be needed
Indications for Neuroimaging in
Patients with Headache Symptoms
   Focal neurological finding
   Headache starting after exertion or Valsalva's
    maneuver
   Acute onset of severe headache
   Headache awakens patient at night
   Change in well-established headache pattern
   New-onset headache in patient >35 years of age
   New-onset headache in patient who has HIV
    infection or previously diagnosed cancer
CASE HISTORY 1
Salma is 37year-old lady. She presents with severe
headache associated with nausea. The headache is
typically present on waking and worsens over the course of
the morning. The pain starts in the temples, affecting the
right more than the left side and is temporarily eased by
pressure. From the temples, the pain gradually spreads to
settle in the back of the head. She always feels nauseous,
but only vomits occasionally during particularly severe
attacks. Eventually he has to stop what he is doing and lie
down in a darkened room. Occasionally, Salma gets a
warning before the attack starts, with a bright spot in his
vision, which slowly expands over about 20 minutes before
disappearing. It is followed by headache.
Explore the Diagnostic Imperatives


  What Conditions/Diagnoses are:


    Most common?

    Most important?
Distinguishing Migraine Aura from a
     Transient Ischemic Attack
International Classification of Headache Disorders.
  Diagnostic criteria for migraine with aura
 A. At least five attacks fulfilling criteria B–D
 B. Headache attacks lasting 4–72 hours (untreated or unsuccessfully
    treated)
 C. Headache has at least two of the following characteristics:
 1. unilateral location
 2. pulsating quality
 3. moderate or severe pain intensity
 4. aggravation by or causing avoidance of routine physical activity (e.g.
    walking or climbing stairs)
 D. During headache at least one of the following:
 1. nausea and/or vomiting
 2. photophobia and phonophobia
 E. Not attributed to another disorder

Source: Headache Classifi cation Subcommittee of the International Headache Society (IHS). The
International Classification of Headache Disorders (2nd edition). Cephalalgia 2004; 24 (suppl 1): 1–160.
International Classification of Headache Disorders.
  Diagnostic criteria for migraine with aura
Typical aura consisting of visual and/or sensory and/or speech
    symptoms. Gradual development, duration no longer than one hour,
    a mix of positive and negative features and complete reversibility
    characterize the aura which is associated with a headache fulfilling
    criteria for migraine without aura
Diagnostic criteria
A. At least two attacks fulfilling criteria B–D
B. Aura consisting of at least one of the following, but no motor
    weakness:
1. fully reversible visual symptoms including positive features (e.g.
    flickering lights, spots or lines) and/or negative features (i.e. loss of
    vision)
2. fully reversible sensory symptoms, including positive features (i.e.
    pins and needles) and/or negative features (i.e. numbness)
3. fully reversible dysphasic speech disturbance
Cont.
  International Classification of Headache Disorders.
  Diagnostic criteria for migraine with aura
C. At least two of the following:
1. homonymous visual symptoms and/or unilateral sensory symptoms
2. at least one aura symptom develops gradually over ≥5 minutes
   and/or different aura symptoms occur in succession over ≥5 minutes
3. each symptom lasts ≥5 and ≤60 minutes
D. Headache fulfilling criteria B–D for migraine without aura (Box 2.1)
   begins during the aura or follows aura within 60 minutes
E. Not attributed to another disorder




Source: Headache Classifi cation Subcommittee of the International Headache Society (IHS). The
International Classification of Headache Disorders (2nd edition). Cephalalgia 2004; 24 (suppl 1): 1–160.
Estimates of migraine prevalence in studied using diagnostic criteria of the
                 International Headache Society (IHS) .
Migraine Treatment




    Empathy
Migraine

Acute Treatment:
   Combination therapy with an oral triptan +NSAID, or
    an oral triptan + paracetamol, for the acute treatment
    of migraine, taking into account the person's preference,
    comorbidities and risk of adverse events.
   For young people aged 12–17 years consider a nasal
    triptan in preference to an oral triptan
   For people who prefer to take only one drug, consider
    monotherapy with an oral triptan , NSAID, aspirin
    (900 mg) or paracetamol for the acute treatment ,
    taking into account the person's preference,
    comorbidities and risk of adverse events.
   Consider an anti-emetic in addition to other acute
    treatment for migraine even in the absence of nausea
    and vomiting.
Migraine

Acute Treatment:




             +
Migraine

Prophylactic Treatment:
   Discuss the benefits and risks of prophylactic
    treatment for migraine with the person, taking into
    account the person's preference, comorbidities, risk
    of adverse events and the impact of the headache
    on their quality of life.
   Offer topiramatec (anti epilepsy) or propranolol
    for the prophylactic treatment of migraine according
    to the person's preference, comorbidities and risk of
    adverse events..
Migraine

   Advise women and girls of childbearing potential that
    topiramate is associated with a risk of fetal
    malformations and can impair the effectiveness of
    hormonal contraceptives. Ensure they are offered
    suitable contraception.
   If both topiramate and propranolol are unsuitable or
    ineffective, consider a course of up to 10 sessions of
    acupuncture over 5–8 weeks or gabapentin (up to
    1200 mg per day) according to the person's
    preference, comorbidities and risk of adverse events.
Migraine
   For people who are already having treatment with
    another form of prophylaxis such as amitriptyline ,
    and whose migraine is well controlled, continue the
    current treatment as required.
   Review the need for continuing migraine prophylaxis
    6 months after the start of prophylactic treatment.
   Advise people with migraine that riboflavin (400
    mg once a day) may be effective in reducing
    migraine frequency and intensity for some people.
Source: Headaches-Diagnosis and management of headaches in
young people and adults . NICE Guidelines, September 2012
Migraine

Prophylactic Treatment:
CASE HISTORY 2
The woman with ‘daily’ headaches
Salem is a 30-year-old policeman and does
shift work. He presents with troublesome
headaches, which he gets most days. The
headache can come on at any time of the
day. Sometimes the pain is on the left side
of his head, but more often it is like a band
across the back of his head. There are no
associated symptoms. The headaches do
not stop him working, but they affect his
ability to concentrate
Explore the Diagnostic Imperatives


  What Conditions/Diagnoses are:


    Most common?

    Most important?
Tension Headache




Prevalence rates of tension-type
headaches vary among studies
from 30 to 71%
Diagnostic Criteria

Tension-type headache
   Headaches lasting from 30 minutes to 7 days
   At least two of the following pain characteristics:
     Pressing    or tightening (non-pulsating) quality
     Mild   to moderate intensity
     Bilateral   location
     No  aggravation from walking stairs or similar routine
      activities
   Both of the following:
     No   nausea or vomiting
     Photophobia     and phonophobia absent, or only one is
      present
Tension-type headache
   Diary cards can aid diagnosis and assessment
    of response to Treatment

   Referral is indicated if the diagnosis is unclear or
    there is no response to standard treatment
    strategies
TENSION-TYPE HEADACHE
     MANAGEMENT




     EMPATHY
Tension Headache
Acute Treatment:
 Aspirin , paracetamol or an NSAID, taking
  into account the person's preference,
  comorbidities and risk of adverse events.

Prophylactic Treatment:
 A course of up to 10 sessions of acupuncture
  over 5–8 weeks for the prophylactic treatment of
  chronic tension-type headache.

Source: Headaches-Diagnosis and management of headaches in
young people and adults . NICE Guidelines, September 2012
Tension Headache

Acute Treatment:




                   +

Prophylactic Treatment:
Rebound Headache
Patients with chronic tension-type
headache should limit their use of
analgesics to two times weekly to
prevent the development of
Chronic daily headache . Or
Rebound headache
Rebound Headache
1.   Daily analgesic medication can be
     withdrawn
2.   Withdrawal symptom frequently reduce
     after 2 weeks
3.   Pt. often show migraine headache
4.   Give migraine specific treatment
Non-pharmacological Treatment
for Headache

   Smoking cessation
   Higher levels of nicotine are correlated
    with trends toward higher measures of
    anger, anxiety, and depression
Non-pharmacological Treatment
for Headache
   biofeedback, relaxation training (No strong
    evidence)
   cognitive psychotherapy alone and in
    combination with other behavioral treatment for
    chronic tension-type headache (No strong
    evidence)
   acupuncture treatment (Evidence level A,
    systematic review of RCTs)
Non-pharmacological Treatment
for Headache:
   Traditional physical therapy for headache
     Proper posture
     Home exercise program
     Used ice packs
     Massage, and “passive mobilization” of the
      cervical facets.
    Both headache frequency and psychologic
    well-being improved significantly

     (Evidence level B, uncontrolled study)
Acute Secondary Headache
   Headache associated with head trauma
   Acute post-traumatic headache
   Headache associated with vascular disorders
   Subarachnoid hemorrhage
   Acute ischemic cerebrovascular disorder
   Unruptured vascular malformation
   Arteritis (e.g., temporal arteritis)
   Venous thrombosis
   Arterial hypertension
   Headache associated with nonvascular
    intracranial disorder
Cont.

Acute Secondary Headache
   Headache associated with metabolic disorder
   Hypoxia
   Dialysis
   Other metabolic abnormality
   Headache or facial pain associated with disorder
    of cranium, neck, eyes, ears, nose, sinuses,
    teeth, mouth, or other facial or cranial structures
   Cranial neuralgias and nerve trunk pain
Cont.

Acute Secondary Headache
   Benign intracranial hypertension
   Low cerebrospinal fluid pressure (e.g. headache
    subsequent to lumbar puncture).
   Headache associated with substance use or
    withdrawal
          Acute use or exposure
          Chronic use or exposure
   Headache associated with noncephalic infection
   Viral infection
   Bacterial infection
Final message and
conclusion:
When dealing with patient suffering from headache

1.   You need to make accurate diagnosis

2.   You need to determine the severity

3.   Show your empathy and give appropriate
     treatment

4.   Do not deprive the patient from preventive
     medications
Migraine and tension headache

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Migraine and tension headache

  • 1. Headache Fayza Rayes MBBCh. Msc. MRCGP Consultant Family Physician Joint Program of Family & Community Medicine, Jeddah www.fayzarayes.com
  • 2. :Contents 1. Approach to patient with headache 2. Migraine 3. Tension headache
  • 3. An Approach to the Headache History 1. How many different headache types does the patient experience? (Separate histories are necessary for each)
  • 4. An Approach to the Headache History 2. Time questions a) Why now? b) How recent in onset? c) How frequent d) What pattern (temporal distribution) d) How long lasting? 3. Character questions a) Intensity of pain? b) Nature and quality of pain? c) Site and spread of pain? d) Associated symptoms?
  • 5. Temporal distribution of different types of headache with time Migraine Tension headache Migraine + Tension (combination) Cluster headache Raised intracranial pressure
  • 7. An Approach to the Headache History 4. Cause questions a) Predisposing and/or trigger factors? b) Aggravating and/or relieving factors? c) Family history of similar headache? 5. Response to headache questions a) What does the patient do during the headache? b) Function limited or prevented? c) Medication
  • 8. An Approach to the Headache History 6. State of health between attacks a) Completely well, or residual or persisting symptoms? b) Concerns, anxieties, fears about recurrent attacks and/or their cause? Source: Steiner TJ, MacGregor EA, Davies PTG. Guidelines for All Healthcare Professionals in the Diagnosis and Management of Migraine, Tension-Type, Cluster and Medication Overuse Headache (3rd edition, 2007). www.bash.org.uk
  • 9. Headache History 1st Consultation
  • 10. Diary Card …what for  Confirm the diagnosis  Assess frequency and duration of the attacks  Assess response to treatment  Identify potential triggers  Involve patient in the managment
  • 11.
  • 13. Headache diary: episodic headaches It shows episodic headache with complete freedom from symptoms between attacks, confirming the diagnosis of migraine with and without aura
  • 14. Headache diary: daily headaches Possible medication overuse) with migraine
  • 15. Headache diary: daily headaches (possible medication overuse) with migraine
  • 16. Episodic Headache & Chronic Headache
  • 17. The mnemonic “SNOOP” as a reminder of the red flags that may point to the potential of a more serious, secondary headache
  • 18. Headache History 2nd Consultation
  • 19. Headache Physical Examination  The examination must be thorough but can be brief.  Examine the head and neck for muscle tenderness , stiffness, limitation in range of movement and crepitation.  Funduscopic examination is mandatory at first presentation with headache, and it is always worthwhile to repeat it during follow-up.  Blood pressure measurement  A quick neurological examination may be needed
  • 20. Indications for Neuroimaging in Patients with Headache Symptoms  Focal neurological finding  Headache starting after exertion or Valsalva's maneuver  Acute onset of severe headache  Headache awakens patient at night  Change in well-established headache pattern  New-onset headache in patient >35 years of age  New-onset headache in patient who has HIV infection or previously diagnosed cancer
  • 21. CASE HISTORY 1 Salma is 37year-old lady. She presents with severe headache associated with nausea. The headache is typically present on waking and worsens over the course of the morning. The pain starts in the temples, affecting the right more than the left side and is temporarily eased by pressure. From the temples, the pain gradually spreads to settle in the back of the head. She always feels nauseous, but only vomits occasionally during particularly severe attacks. Eventually he has to stop what he is doing and lie down in a darkened room. Occasionally, Salma gets a warning before the attack starts, with a bright spot in his vision, which slowly expands over about 20 minutes before disappearing. It is followed by headache.
  • 22. Explore the Diagnostic Imperatives What Conditions/Diagnoses are: Most common? Most important?
  • 23. Distinguishing Migraine Aura from a Transient Ischemic Attack
  • 24.
  • 25. International Classification of Headache Disorders. Diagnostic criteria for migraine with aura A. At least five attacks fulfilling criteria B–D B. Headache attacks lasting 4–72 hours (untreated or unsuccessfully treated) C. Headache has at least two of the following characteristics: 1. unilateral location 2. pulsating quality 3. moderate or severe pain intensity 4. aggravation by or causing avoidance of routine physical activity (e.g. walking or climbing stairs) D. During headache at least one of the following: 1. nausea and/or vomiting 2. photophobia and phonophobia E. Not attributed to another disorder Source: Headache Classifi cation Subcommittee of the International Headache Society (IHS). The International Classification of Headache Disorders (2nd edition). Cephalalgia 2004; 24 (suppl 1): 1–160.
  • 26. International Classification of Headache Disorders. Diagnostic criteria for migraine with aura Typical aura consisting of visual and/or sensory and/or speech symptoms. Gradual development, duration no longer than one hour, a mix of positive and negative features and complete reversibility characterize the aura which is associated with a headache fulfilling criteria for migraine without aura Diagnostic criteria A. At least two attacks fulfilling criteria B–D B. Aura consisting of at least one of the following, but no motor weakness: 1. fully reversible visual symptoms including positive features (e.g. flickering lights, spots or lines) and/or negative features (i.e. loss of vision) 2. fully reversible sensory symptoms, including positive features (i.e. pins and needles) and/or negative features (i.e. numbness) 3. fully reversible dysphasic speech disturbance
  • 27. Cont. International Classification of Headache Disorders. Diagnostic criteria for migraine with aura C. At least two of the following: 1. homonymous visual symptoms and/or unilateral sensory symptoms 2. at least one aura symptom develops gradually over ≥5 minutes and/or different aura symptoms occur in succession over ≥5 minutes 3. each symptom lasts ≥5 and ≤60 minutes D. Headache fulfilling criteria B–D for migraine without aura (Box 2.1) begins during the aura or follows aura within 60 minutes E. Not attributed to another disorder Source: Headache Classifi cation Subcommittee of the International Headache Society (IHS). The International Classification of Headache Disorders (2nd edition). Cephalalgia 2004; 24 (suppl 1): 1–160.
  • 28. Estimates of migraine prevalence in studied using diagnostic criteria of the International Headache Society (IHS) .
  • 30. Migraine Acute Treatment:  Combination therapy with an oral triptan +NSAID, or an oral triptan + paracetamol, for the acute treatment of migraine, taking into account the person's preference, comorbidities and risk of adverse events.  For young people aged 12–17 years consider a nasal triptan in preference to an oral triptan  For people who prefer to take only one drug, consider monotherapy with an oral triptan , NSAID, aspirin (900 mg) or paracetamol for the acute treatment , taking into account the person's preference, comorbidities and risk of adverse events.  Consider an anti-emetic in addition to other acute treatment for migraine even in the absence of nausea and vomiting.
  • 32. Migraine Prophylactic Treatment:  Discuss the benefits and risks of prophylactic treatment for migraine with the person, taking into account the person's preference, comorbidities, risk of adverse events and the impact of the headache on their quality of life.  Offer topiramatec (anti epilepsy) or propranolol for the prophylactic treatment of migraine according to the person's preference, comorbidities and risk of adverse events..
  • 33. Migraine  Advise women and girls of childbearing potential that topiramate is associated with a risk of fetal malformations and can impair the effectiveness of hormonal contraceptives. Ensure they are offered suitable contraception.  If both topiramate and propranolol are unsuitable or ineffective, consider a course of up to 10 sessions of acupuncture over 5–8 weeks or gabapentin (up to 1200 mg per day) according to the person's preference, comorbidities and risk of adverse events.
  • 34. Migraine  For people who are already having treatment with another form of prophylaxis such as amitriptyline , and whose migraine is well controlled, continue the current treatment as required.  Review the need for continuing migraine prophylaxis 6 months after the start of prophylactic treatment.  Advise people with migraine that riboflavin (400 mg once a day) may be effective in reducing migraine frequency and intensity for some people. Source: Headaches-Diagnosis and management of headaches in young people and adults . NICE Guidelines, September 2012
  • 36. CASE HISTORY 2 The woman with ‘daily’ headaches Salem is a 30-year-old policeman and does shift work. He presents with troublesome headaches, which he gets most days. The headache can come on at any time of the day. Sometimes the pain is on the left side of his head, but more often it is like a band across the back of his head. There are no associated symptoms. The headaches do not stop him working, but they affect his ability to concentrate
  • 37. Explore the Diagnostic Imperatives What Conditions/Diagnoses are: Most common? Most important?
  • 38. Tension Headache Prevalence rates of tension-type headaches vary among studies from 30 to 71%
  • 39. Diagnostic Criteria Tension-type headache  Headaches lasting from 30 minutes to 7 days  At least two of the following pain characteristics:  Pressing or tightening (non-pulsating) quality  Mild to moderate intensity  Bilateral location  No aggravation from walking stairs or similar routine activities  Both of the following:  No nausea or vomiting  Photophobia and phonophobia absent, or only one is present
  • 40. Tension-type headache  Diary cards can aid diagnosis and assessment of response to Treatment  Referral is indicated if the diagnosis is unclear or there is no response to standard treatment strategies
  • 41. TENSION-TYPE HEADACHE MANAGEMENT EMPATHY
  • 42. Tension Headache Acute Treatment:  Aspirin , paracetamol or an NSAID, taking into account the person's preference, comorbidities and risk of adverse events. Prophylactic Treatment:  A course of up to 10 sessions of acupuncture over 5–8 weeks for the prophylactic treatment of chronic tension-type headache. Source: Headaches-Diagnosis and management of headaches in young people and adults . NICE Guidelines, September 2012
  • 43. Tension Headache Acute Treatment: + Prophylactic Treatment:
  • 44. Rebound Headache Patients with chronic tension-type headache should limit their use of analgesics to two times weekly to prevent the development of Chronic daily headache . Or Rebound headache
  • 45. Rebound Headache 1. Daily analgesic medication can be withdrawn 2. Withdrawal symptom frequently reduce after 2 weeks 3. Pt. often show migraine headache 4. Give migraine specific treatment
  • 46. Non-pharmacological Treatment for Headache  Smoking cessation  Higher levels of nicotine are correlated with trends toward higher measures of anger, anxiety, and depression
  • 47. Non-pharmacological Treatment for Headache  biofeedback, relaxation training (No strong evidence)  cognitive psychotherapy alone and in combination with other behavioral treatment for chronic tension-type headache (No strong evidence)  acupuncture treatment (Evidence level A, systematic review of RCTs)
  • 48. Non-pharmacological Treatment for Headache:  Traditional physical therapy for headache  Proper posture  Home exercise program  Used ice packs  Massage, and “passive mobilization” of the cervical facets. Both headache frequency and psychologic well-being improved significantly (Evidence level B, uncontrolled study)
  • 49. Acute Secondary Headache  Headache associated with head trauma  Acute post-traumatic headache  Headache associated with vascular disorders  Subarachnoid hemorrhage  Acute ischemic cerebrovascular disorder  Unruptured vascular malformation  Arteritis (e.g., temporal arteritis)  Venous thrombosis  Arterial hypertension  Headache associated with nonvascular intracranial disorder
  • 50. Cont. Acute Secondary Headache  Headache associated with metabolic disorder  Hypoxia  Dialysis  Other metabolic abnormality  Headache or facial pain associated with disorder of cranium, neck, eyes, ears, nose, sinuses, teeth, mouth, or other facial or cranial structures  Cranial neuralgias and nerve trunk pain
  • 51. Cont. Acute Secondary Headache  Benign intracranial hypertension  Low cerebrospinal fluid pressure (e.g. headache subsequent to lumbar puncture).  Headache associated with substance use or withdrawal  Acute use or exposure  Chronic use or exposure  Headache associated with noncephalic infection  Viral infection  Bacterial infection
  • 52. Final message and conclusion: When dealing with patient suffering from headache 1. You need to make accurate diagnosis 2. You need to determine the severity 3. Show your empathy and give appropriate treatment 4. Do not deprive the patient from preventive medications