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FOUR-S PharmaHealth Track
                                                                                                                                  23thJan– 5thFeb’11




                PharmaHealth TRACK
                                     Newsletter on Indian Healthcare Industry


  Top Story                                                                                    Content

 Results Update
                                                                                            Private Equity                                      2
 Healthcare Pharma sector has seen overall positive results this
 quarter. Sector has shown strong 28% y-o-y growth in revenue                               Mergers & Acquisitions                              3
 for the major companies with results declared till now. Though
 profit has seen the muted growth this quarter as many
 companies has seen decrease in net margin q-o-q basis.
                                                                                            News Update                                         4

 Dr Reddys Laboratories Q3 net profit at `5129.60 mn                                        Regulatory Developments                             6
 Drug firm Dr Reddy's Laboratories consolidated net profit rose                             Upcoming Events                                     7
 by 87.80 per cent to `5129.6mn in the third quarter ended
 December 31, 2011 vis-a-vis the corresponding year-ago
 period. The company had posted a net profit of `2731.4mn for                               Stock Market Update                                 8
 the corresponding period of the previous fiscal. Company's net
 income from sales and services rose to `27691.9mn in the third                             Peer Benchmarking                                   8
 quarter ended December 31, 2011, from `18,985.1mn for the
 same period last fiscal. Company's net income from sales and
 services rose to `27,691.9mn in the third quarter ended                                    About Four-S Services                               10
 December 31, 2011, from `18,985.1mn for the same period last
 fiscal. For the nine months ended December 31, 2011, the
 company posted a net profit of `10,835mn, compared to
 `7,695.1mn for the same period last fiscal.




About Four-S Services
Four-S Services is India's leading provider of Research, Financial Consulting and Investment Banking services with offices in Gurgaon, Mumbai and
Bangalore. We have a proven track record of consistently delivering high quality solutions, enabling our clients to improve the effectiveness of decision
making and acting as a catalyst in achieving business success. We have executed more than 120 mandates across diverse range of industries including
Education, Financial Services, Infrastructure, M&E, IT-ITeS, Auto and Auto ancillaries, Retail, Real Estate and Textile etc
Our Services:
   Strategy Consulting                        Research Support
   Business Planning                          Valuation Services
   Investment Banking                         Investor Relations & IPO Consulting
For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com




Research Desk
Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for
prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s Top 5 PE
Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
FOUR-S PharmaHealth Track
 Investment Activity last 1 year..



Date           Investor(s)                                   Target                Stake (%)         Amount ($mn)                   Business         Stage
                                               Aizant Drug Research                    NA
17-Jan-2011 Zephyr Peacock India                                                                            5.0              CRO                    Early
                                               Solutions Ltd
                                               Integrated Health &                     NA
18-Jan-2011 Halcyon Capital Advisor                                                                        44.2              Hospitals             Buyout
                                               Healthcare Services
               Sequoia Capital, Elevar                                                 NA
28-Jan-2011                                    Glocal Healthcare Systems                                    3.3              Hospitals              Early
               Equity
15-Apr-2011 Avigo Capital                      SRL                                    9.27                  224              Diagnostics           Growth

5-May-2011 Sabre Partners                      SRL                                      4                   112              Diagnostics           Growth
            Aquarious India,
17-Jun-2011                         Vaatsalya                                          NA                   10               Hospitals             Growth
            SeedFund
            Catamaran, Reliance VA,
20-Jun-2011                         Wellspring Healthcare                              NA                   4.6              Hospitals             Growth
            Bluecross BlueShield VP
23-Jun-2011 HDFC PE                            Angels Health Pvt Ltd                   12                   0.6              Online Healthcare      Early
                                                                                                                             Super specialty
10-Aug-2011 Matrix Partners                    Kids Clinic                             NA                   10                                      Early
                                                                                                                             hospital chain
28-Sep-2011 Sequoia Capital                    Moolchand Medcity                       NA                  22.0              Hospitals             Growth
              Helion Ventures, Nexus
10-Oct-2011                                    Eye-Q                                   NA                   NA               Hospitals             Growth
              Ventures
28-Nov-2011 Fidelity Growth Partners           XCyton Diagnostics                      NA                   NA               Diagnostics           Growth

12-Jan-2012 NEA, DaVita Inc                    NephroLife Care                         NA                  25.0              Hospitals              Growth
               Sequoia Capital,
11-Jan-2012                                    Healthkart.Com                          NA                   5.1              Health Services         Early
               Omidyar Network
18-Jan-2012 Olympus Capital                    DM Healthcare                           NA                  100.0             Hospitals              Growth

20-Jan-2012 Songs Investments                  Be Well Hospitals                       NA                   NA               Hospitals              Growth
               OrbiMed, Ascent                 Kerala Institute of Medical
25-Jan-2012                                                                            NA                  33.3              Hospitals                Late
               Capital                         Science

                                                                                                                   Source: Four-S Database




   Four-S Indian PE Directory 2010” – A Guide to choosing private equity partners
                         Detailed listing of ~330 Active PE/VC Investors in India - PE/VC players that have invested in the past 3 years.
                         A first-of-its-kind, the directory offers “Deal History” in India for individual investor.
                         Management, investment profile and Contact details.
                         User-friendly Spreadsheet Format.
                         It comes from Four-S Services, the most trusted deal information bank in India.




 Research Desk
 Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for
 prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s Top 5 PE
 Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
FOUR-S PharmaHealth Track
Mergers & Acquisition

Date             Investor(s)                    Target                                        Stake         Amount ($mn)         Business
                                                                                              (%)

19-Jan 2011      Transasia Bio-Medicals         Diasis Diagnostic Systems                        NA               NA             Diagnostics

20-Jan 2011      Surya Pharmaceuticals          ActivOn                                          NA               22.3           Pharma
                                                Bioserve Clinical Research Private
23-Feb-2011      QPS Holdings                   Limited                                          NA               NA             Clinical Research

15-Apr-2011      Ecron Ecunova                  aCROnordic                                      75%               3.4            CRO

15-Apr-2011      Hikma Pharmaceuticals          Unimark Remedies                               22.2%              33.3           Pharma

15-Apr-2011      Fortis Healthcare              SRL                                             86%              189.4           Diagnostics
15-Jun-2011      Lupin                          Goanna Brand                                     NA               NA             OTC

17-Jun-2011      Zydus                          Nesher Pharma unit                               NA               NA             Generic

19-Jul-2011      Shilpa Medicare                Nu Therapeutics                                  50               NA             Pharma

21-Jul-2011      Dr Reddy’s Laboratories        JBCL-Russia-CIS prescription products           100               30.5           Pharma

28-Jul-2011      Cadila Healthcare              Bremer Pharma                                   100               NA             Pharma

3-Aug-2011       Danone                         Wockhardt 's nutrition business                 100               355            Pharma

9-Aug-2011       Ipca Labs                      Onyx Research                                   100               7.5            Healthcare Services

10-Aug-2011      Fortis                         Hoan My Medical                                  65                64            Hospitals

12-Sep-2011      Vivimed Labs                   Octtantis Nobel Labs Ltd                         50               NA             Pharma

8-Oct-2011       Akorn Inc                      KilitchDrugs (India) Ltd                         NA               40.1           Pharma

12-Oct-2011      Life Healthcare Group          Max Healthcare Ltd.                              NA              103.1           Hospitals
                                                Universal Medicare - branded
                                                                                                                                 Pharma
4-Nov-2011       Aventis Pharma                 nutraceutical formulations biz                   NA              114.0
                                                Shalaks Pharmaceuticals -
                                                                                                                                 Pharma
14-Nov-2011      Invida Group                   dermatology and baby care                       100               19.1

18-Nov-2011      Lupin Limited                  I'rom Pharma                                    100               NA             Pharma

24-Nov-2011      SOHM Inc                       Novatrend Medicament                             NA               NA             Pharma
                                                Transgene Biotek bio generic product
                                                                                                                                 Pharma
23-Nov-2011      TSS EXPORT GmbH FZE            - Erythropoietin                                100               5.0

28-Nov-2011      Vivimed Labs                   Uquifa                                          100               55.0           Pharma

17-Jan-2012      Dishman Pharma                 Creapharm Parenterals                             100                NA           Pharma

24-Jan-2012        Watson Pharmaceuticals        Ascent Pharma Health Ltd.                        NA               393             Pharma

1-Feb-2012         Fortis Healthcare             RadLink-Asia Pte Ltd                              85               50            Diagnostic

2-Feb-2012         Aanjaneya Lifecare            Apex Drugs and Intermediaries Ltd                100               50             Pharma


                                                                                                 Source: Four-S Database

Research Desk
Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for
prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s Top 5 PE
Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
FOUR-S PharmaHealth Track
 News Update
Healthcare & Pharmaceutical Sector                                                Pfizer posts profit of `482.8mn in Q3

1.) Pharmaceutical Sector                                                         Pfizer Ltd reported a net profit of `482.8mn and a net profit of
                                                                                  `435.8mn for the third quarter ended December 31, 2011. Net
Result Update Continue….
                                                                                  sales of the company stood at `2518.8mn for the third quarter
                                                                                  ended December 31, 2011 compared to `2358.4mn for the third
Piramal Healthcare Q3 cons net profit at `85.20 mn
                                                                                  quarter ended November 30, 2010. For the nine months ended
                                                                                  December 31, 2011, the company posted a net profit of
Piramal Healthcare Ltd has posted a net profit of `85.20 mn for
                                                                                  `1365.1mn compared to `1207.5mn for the third quarter ended
the quarter ended December 31, 2011 whereas the same was
                                                                                  November 30, 2010.
at `603.30 mn for the quarter ended December 31, 2010. Total
Income is `6175.70 mn for the quarter ended December 31,
                                                                                  TCG Lifesciences completes key milestones on delivery of
2011 whereas the same was at `5348.80 million for the quarter
                                                                                  pre-clinical drug candidates
ended December 31, 2010.
                                                                                  TCG Lifesciences Limited (TCGLS) announced the achievement of
For Q3FY2012, Pharma Solutions (CRAMS) business registered
                                                                                  two distinct milestones in their ongoing drug discovery
strong growth of 57.4% with sales of `3.673bn as compared to
                                                                                  partnership with Endo Pharmaceuticals. TCGLS will receive
`2.334bn in Q3FY2011. The revenues from Indian facilities grew
                                                                                  undisclosed success fees against these milestones.
by 68.9 % to `2.24bn.

Divis Labs Q3 profit up 20.65 pc at `1225.5mn                                     In the first of two fully integrated discovery programs with Endo
                                                                                  aimed at identifying novel small molecule drug candidates for an
Drug firm Divis Laboratories net profit rose by 20.65 per cent to                 unmet medical need, TCGLS has successfully delivered a pre-
`1225.5mn for the third quarter ended December 31, 2011                           clinical development candidate. In the second, TCGLS has
compared to a net profit of `1015.7mn for the quarter ended                       designed and delivered novel fast-follower hit structures well
December 31, 2010. Total income of the company stood at                           within collaboration timelines. This multi-year, three-stage
`4,174.2mn for the quarter ended December 31, 2011 as                             project aims to identify potent in-vivo active novel blockers of
against `3,149.7mn for the corresponding period previous fiscal                   an undisclosed target for eventual clinical development.

Lupin Q3 net up 4.95% at `2351mn                                                  Two lead molecules resulting from this collaboration have been
                                                                                  selected by Endo for cGMP manufacturing and GLP-toxicology
Drug firm Lupin consolidated net profit rose by 4.95 per cent to                  studies.
`2,351mn for the third quarter ended December 31, 2011
compared to net profit of `2240mn for the corresponding                           Pfizer recalls 1 mn packets of birth control pills
period of previous fiscal. Net sales of the company grew by 21.9
per cent to `17,917mn for the third quarter, compared to                          American pharmaceutical giant Pfizer has announced recall of
`14,694mn in the same period previous fiscal.                                     more than one million packets of birth control pills after it found
                                                                                  out that inactive or placebo pill may have been placed out-of-
Glenmark Pharma Q3 net profit down 46%                                            order in some packs. Company has announced a voluntary recall
                                                                                  of Lo/Ovral-28 (norgestrel and ethinyl estradiol) and Norgestrel
Glenmark Pharmaceuticals Ltd has posted a net profit after tax                    and Ethinyl Estradiol Tablets (generic) birth control pills in the
of `461.18 million for the quarter ended December 31, 2011 as                     United States. Its voluntary recall is based on its own internal
compared to `865.25 million for the quarter ended December                        assessments of this problem, in which it found that the inactive
31, 2010. Total Income has increased from `7732.79 million for                    or placebo pill may have been placed out-of-order in some
the quarter ended December 31, 2010 to `10418.45 million for                      packs.
the quarter ended December 31, 2011. The company took a hit
of `1.02bn on dollar denominated loans due to rupee                               State Bank of Mysore files criminal complaint against
depreciation. During the quarter, net sales stood at                              Sterling Biotech for 'repayment dafault'
`10,310.8mn as against `7486.4mn in the corresponding period
previous fiscal                                                                   State Bank of Mysore has filed a criminal complaint against
                                                                                  Sterling Biotech, and its six directors, for allegedly defaulting on
                                                                                  repayments on credit facilities provided by the public sector
                                                                                  lender.


Research Desk
Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects
for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s
Top 5 PE Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
FOUR-S PharmaHealth Track

In its complaint, the bank has said that cheques worth 580mn                      Piramal Group picks up an additional 5.5% stake in
submitted by the company have bounced. The cheques were                           Vodafone India for `30.07bn
drawn on Andhra Bank. Sterling Biotech is the flagship company
of Gujarat-based Sandesara Group. Sterling Biotech has 7.5%                       Piramal Healthcare Ltd would buy a 5.5 per cent stake in
stake in the world gelatin market and has 60% share in the local                  Vodafone's India unit, Essar, for `30.07bn ($616.14 million),
market.                                                                           taking its total stake in the mobile company to about 11 per
                                                                                  cent.
Indoco Remedies signs strategic pact with DSM Pharma
                                                                                  The sale would mark the exit of Essar as Vodafone's joint
Indoco Remedies Ltd. has entered into a strategic business                        venture partner in India after the London-listed company last
alliance with DSM Pharmaceutical Products NV. DSM                                 year sealed a long awaited deal to buy out Essar in July.
Pharmaceutical Products NV is a constituent of the Royal DSM                      Vodafone last year bought 22 per cent of Essar and Piramal
NV, Austria.                                                                      bought 5.5 per cent.

Under the agreement reached, DPP will market and sell eight                       The transaction contemplates various exit options for Piramal,
active pharma ingredients (APIs) manufactured by Indoco in                        including both participation in a potential IPO of the unit and a
Austria and other international markets.                                          sale of its stake back to Vodafone

Fondaparinux injection issue resolved with USFDA: Dr                              2.) Healthcare
Reddy's Laboratories
                                                                                  Fortis Healthcare arm acquires 85% stake in RadLink-Asia
Drug firm Dr Reddy's Laboratories has resolved all issues raised
by a division of US health regulator over its promotional                         Fortis Healthcare Singapore Pte, Fortis Healthcare India offshore
material for an anti-coagulant injection.                                         subsidiary, has acquired 85% stake in RadLink-Asia Pte Ltd
                                                                                  ("RadLink"), an outpatient diagnostic and molecular imaging
Office of Prescription Drug Promotion (OPDP) had issued a letter                  chain in Singapore, for a purchase consideration of S$62.9
to the company for changes related to certain promotional                         million.
material for Fondaparinux Sodium for Injection. The company
has already addressed all matters raised by the Division of                       The transaction provides Fortis Healthcare a strong foothold in
Professional Promotion (DPP), USFDA in the letter issued on                       the premium diagnostics and molecular imaging segment in one
January 10, 2012. The DPP informed Dr Reddy's Lab on January                      of Southeast Asia's most attractive markets besides providing a
24, 2012 that the matters are now considered closed.                              complementary platform to its upcoming specialty hospital on
                                                                                  Adam Road in Singapore.
OPDP through the letter had intimated to the Hyderabad- based
drug firm that the company's information on a promotional                         Radlink has four main business segments; diagnostic imaging,
website for Fondaparinux Sodium Solution for subcutaneous                         molecular imaging, cyclotron (radio-isotopes manufacturing)
injection was misleading.                                                         and GP clinics.

US drugmaker Eli Lilly, Jubilant Life call off joint venture                      Fortis Healthcare invests SGD70 million in 2 Singapore
                                                                                  healthcare ventures
US drugmaker Eli Lilly & Company and Noida-based Jubilant
Life Sciences have called off their equal drug-discovery                          Indian healthcare group Fortis is investing SGD 70 million (about
partnership to develop molecules across several therapeutic                       `2.74bn) in two colorectal centres in Singapore this year. Fortis
areas.                                                                            Healthcare Singapore had opened a outpatient clinic for
                                                                                  colorectal diseases, Novena Colorectal Centre, and a 31-
The 50:50 JV, formed in late 2008 between Jubilant Life                           bed Fortis Hospital for Colorectal Diseases in June this year.
Sciences' wholly-owned subsidiary Jubilant Biosys and Lilly, was                  Fortis has started hiring nurses and allied health professionals
to develop molecules from the pre-clinical to phase II stage                      for 80 positions at the clinic and hospital. The hospital would
across oncology, diabetes and cardiovascular segments. The firm                   serve 40 patients a day while the clinic would be a group
is called Vanthys Pharmaceuticals and based in Bangalore.                         practice by four colorectal specialists who also have deeper
                                                                                  expertise in areas such as robotic surgery to genetic testing.




Research Desk
Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects
for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s
Top 5 PE Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
FOUR-S PharmaHealth Track

Fortis to raise US$300mn via IPO of non-core biz                                  written records, not prevented contamination of sterile drugs at
                                                                                  its facilities, inadequately tested drugs, and submitted false data
Fortis Healthcare (India) is planning to raise $300 mn by spinning                to the FDA. The company made adulterated and potentially
off its non-core business into a separate company, which will                     unsafe drugs that were illegal to sell, it claimed.
then be listed on the Singapore Stock Exchange. Hospitals
operator Fortis, controlled by billionare brothers Malvinder and
Shivinder Singh, expects the restructuring to be completed by
                                                                                     Global News Update
the middle of next month.                                                         Valeant gives up on bid to buy Ista

The initial public offering is likely to hit the market in May or                 Valeant    Pharmaceuticals       International,     pharmaceutical
June this year.                                                                   company, headquartered in Canada, has withdrawn its offer to
                                                                                  acquire Ista Pharmaceuticals, a US based pharmaceutical
3.)   Regulations/Legal                                                           company that specializes in ophthalmic pharmaceutical
                                                                                  products, a fortnight after upping its bid for the eye specialist.
Orchid Pharma receives USFDA nod for Levofloxacin Tabs
ANDA                                                                              Just before Christmas, Valeant's $6.50 per share offer, which
                                                                                  valued Ista at $314 million, was dismissed as "grossly
The Chennai-based global pharma major, Orchid Chemicals &                         inadequate" by the latter. However, Valeant then raised its
Pharmaceuticals Ltd has received approval from the US FDA for                     initial proposal to $7.50 per share in cash and set a target price
its ANDA (Abbreviated New Drug Application) for Levofloxacin                      of $8.50 per share in cash, subject to one week of due diligence.
Tablets in the 250 mg, 500 mg and 750 mg strengths.
                                                                                  Amgen hits acquisition trail to snap up Micromet as profits
                                                                                  slip
Lupin gets USFDA approval for diabetes drug
                                                                                  Amgen, a international biotechnology company, headquartered
Drug firm Lupin has received approval from the US health
                                                                                  in California, has opened its wallet and unveiled plans to buy
regulator for its Metformin Hydrochloride Extended Release
                                                                                  Micromet, a biotech with its R&D centre in Munich and
tablets, used in treating diabetes. The company's US-based
                                                                                  headquarters in Rockville, USA, for $1.16 billion.
subsidiary Lupin Pharmaceuticals Inc has received tentative
approval from US Food and Drug Administration (USFDA) for
                                                                                  Amgen is offering $11 per share in cash, and the acquisition
Metformin tablets in strengths of 500 mg and 1,000 mg. Lupin's
                                                                                  includes blinatumomab, a bispecific T cell engager (BiTE)
Metformin HCl ER Tablets are the AB-rated generic equivalent of
                                                                                  antibody in Phase II for acute lymphoblastic leukaemia. The drug
Santarus Inc's Glumetza HCl ER Tablets. According to IMS
                                                                                  is also in studies for non-Hodgkin's lymphoma.
Health data, Glumetza HCl ER tablets in strengths of 500 mg and
1,000 mg had annual US sales of nearly USD 58 million for the 12
                                                                                  The companies already have a partnership in place. In July last
months to September, 2011.
                                                                                  year, they signed a deal involving the development of BiTE
                                                                                  antibodies against three undisclosed solid tumour targets.
Ranbaxy settles row with USFDA; to upgrade plants in India
and US
                                                                                  Micromet's pipeline includes solitomab, a BiTE antibody in
Ranbaxy Laboratories has agreed to make significant changes in                    Phase I for advanced solid tumours. Amgen will also be entitled
its manufacturing facilities in India and the US as part of a                     to milestone and royalties from the company's existing licensees
settlement that seeks to end wide-ranging investigations against                  of BiTE (such as Sanofi, AstraZeneca, Boehringer Ingelheim and
the drug maker by the US regulatory authorities.                                  Bayer) and other technologies.

A consent decree, signed between Ranbaxy and the US Food                          Celgene to acquire Avila
and Drug Administration (FDA) last month and filed in a US court
                                                                                  Celgene Corp, a manufacturer of drug therapies for cancer and
on Wednesday, extends the ban on supply of drugs from four
                                                                                  inflammatory disorders, headquartered in New Jersey, is to
plants to the US market until the Indian drug maker resolves the
                                                                                  acquire privately-held Avila Therapeutics in a deal that could be
problems at these facilities, dashing hopes of the embargo being
                                                                                  worth up to $925 million.
lifted immediately after the settlement.
                                                                                  Celgene is paying $350 million in cash, plus up to $195 million
The US Department of Justice (DoJ), which filed the consent
                                                                                  for milestones related to the progress of AVL-292, an oral
decree at the request of the FDA, said Ranbaxy had not kept

Research Desk
Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects
for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s
Top 5 PE Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
FOUR-S PharmaHealth Track

covalent drug that inhibits Bruton’s tyrosine kinase which                        stockholder rights agreement, which is "designed to deter
currently in Phase I for non-Hodgkin’s lymphoma, B cell chronic                   coercive or otherwise unfair takeover tactics". Earlier this week,
lympocytic leukaemia and rheumatoid arthritis.                                    the Swiss major, having been rebuffed by Illumina's board a
                                                                                  number of times over the last month, made an unsolicited offer
The deal also includes up to $380 million in potential milestone                  of $44.50 a share in cash, which represents a premium of about
payments contingent upon the development and approval of                          18% to Illumina's stock price on January 24.
candidates generated from Avila's Avilomics platform.
                                                                                  The rights agreement means that Illumina shareholders can buy
Illumina adopts 'poison pill' to deter Roche approach                             $550 in common shares for just $275 if a bidder acquires 15% of
                                                                                  the company’s stock. The effect of this would be make Illumina
Illumina is adopting a 'poison pill' in a bid to block Roche’s $5.7               more expensive to acquire.
billion hostile takeover offer.

The US company, which develops tools and systems for the
analysis of genetic variation and function, has announced a




 Events Calendar




     India Pharma Convention                                                 BioAsia 2012: The Global Biobusiness Forum
     Date: Feb 12, 2012                                                      Date: 9 Feb 12 – 11 Feb 2012
     Venue: DIPSAR, Delhi                                                    Venue: Hyderabad International Convention Centre, Hyderabad
                                                                             Organizer: BioAsia
     Organizer: Udyog Development Foundation
                                                                             Tel: 91 – 40 – 66446477
     website: www.udfoundation.com                                           E-mail: info@bioasia.in

     Medical Fair India                                                      PHARMA Pro&Pack 2013
     Date: 2 Mar-4 Mar, 2012                                                 Date: Apr 24-26, 2012
     Venue: Bombay exhibition center, Mumbai                                 Venue: Mumbai exhibition center, Goregaon, Mumbai
     Webmail: http://ems2012.in/                                             Website: http://www.pharmapropack.com
     Organizer : Messe Duesseldorf                                           Email: contact@pharmapropack.com
     http://www.medicalfair-india.com/




Research Desk
Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects
for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s
Top 5 PE Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
FOUR-S PharmaHealth Track

  Stock Market Update


   As on 21 Jan 2012                  Market Cap               Price                             Percentage Change (%)
                                         In `Mn                 In `           1W               1M           3M               6M           1 Year
   SUN PHARMACE                            547616                529          2.89           5.62            8.13            5.23            8.28
   DR.REDDY'S L                            287598              1696          -0.64           4.74            8.05            4.97           -1.63
   CIPLA LTD.                              266409                332         -0.70           2.09           16.08            5.76           -4.35
   LUPIN LTD                               197597                442          2.62           3.15            -6.22          -4.63           -5.05
   RANBAXY LABO                            195380                463          0.84          18.39            -6.65         -12.90          -17.01
   GLAXOSMITH                              166645              1967           0.13           6.42            -6.40         -14.76          -13.40
   CADILA HEALTH                           133844                654         -3.64           -8.16         -13.70          -26.20          -21.57
   DIVI's LAB                              103787                782         -0.22           5.27            7.16           -5.62           24.01
   GLENMARK PHA                             86251                319          1.55          13.82            9.99            1.54            0.02
   APOLLO HOSPITAL                          84015                625         -3.55          15.35           17.83           22.32           27.13
   PIRAMA HEALTH                            71786                416          0.59          12.31           16.50            3.44           -9.66
   BIOCON LTD                               54980                275          1.76           5.98          -21.81          -26.86          -26.65
   OPTO CIRCUIT                             41576                223          9.03          27.25            -4.06         -15.20           -9.65
   IPCA LAB LTD                             35016                279          1.22          10.91           13.60          -16.88          -14.08
   JUBILANT ORG                             28798                181         -4.05           7.98            -9.40         -18.47          -28.51
   AUROBINDO PH                             28195                 97         -6.71          12.73          -20.27          -41.97          -60.26
   ORCHID CHEM                              10785                153          7.07          24.21            0.52          -32.13          -48.87
   BSE SENSEX                                                17,605            2.2           10.5              0.7           -1.9            -4.6
   NSE NIFTY                                                 15,695           -4.1           -9.0             -2.8          -12.1           -18.8
   BSE HEALTHCARE                                             5,326            2.3           11.8              1.1           -1.5            -3.6

    Quarterly Results                                                                                                                  `in million

Companies                          Revenue                               EBITDA                              PAT                            Margins JAS’
                           OND’        OND’          YoY       OND’         OND’          YoY        OND’    OND’                YoY     EBITDA% NPM %
                           FY10         FY11                   FY10         FY11                     FY10     FY11                          FY’11     FY’11
DR.REDDY'S L          18985.10     27691.90        45.9    3801.70      8688.20         128.5     2731.40  5129.60              87.8        31.37     18.52
RANBAXY LABO          19283.60     20955.31         8.7    2483.89      -769.17        -131.0     3079.36 -4645.80            -250.9         -3.67   -22.17
SUN PHARMACE          13314.20     18946.00        42.3    4670.40      7840.40          67.9     5036.50  5977.40              18.7        41.38     31.55
LUPIN LTD             15102.10     18189.30        20.4    2972.60      3735.00          25.6     2240.30  2350.60               4.9        20.53     12.92
CIPLA LTD.            16343.90     17780.20         8.8    3665.60      4376.10          19.4     2630.10  3089.70              17.5        24.61     17.38
CADILA HEALTH         11668.10     13832.20        18.5    2561.70      2615.90           2.1     1620.10  1492.10              -7.9        18.91     10.79
JUBILANT ORG           8689.70     10884.90        25.3    1321.50      2083.90          57.7      441.10  -783.90            -277.7        19.14     -7.20
AUROBINDO PH          11126.20     10753.00        -3.4    2542.20      -707.90        -127.8     1983.20  -801.60            -140.4         -6.58    -7.45
GLENMARK PHA           7491.41     10313.12        37.7    1338.91      1028.65         -23.2      865.25   461.18             -46.7          9.97     4.47
APOLLO HOSP            5864.00      6997.50        19.3     996.00      1165.00          17.0      495.50   557.60              12.5        16.65      7.97
IPCA LAB LTD           4663.60      6148.30        31.8     909.90      1113.90          22.4      639.50   639.30               0.0        18.12     10.40
GLAXOSMITH             5892.70      6146.20         4.3    2159.60      1830.40         -15.2     1578.10  1458.60              -7.6        29.78     23.73
OPTO CIRCUIT           4176.60      6112.94        46.4    1228.18      1710.36          39.3      956.75  1250.85              30.7        27.98     20.46
PIRAMA HEALTH          4026.90      5587.00        38.7    -325.60      -502.10          54.2      603.30    85.20             -85.9         -8.99     1.52
BIOCON LTD             5113.80      5185.10         1.4    1642.40      1287.20         -21.6     1007.60   848.50             -15.8        24.82     16.36
ORCHID CHEM            3817.97      4194.92         9.9     734.77      1059.09          44.1      240.15  -565.68            -335.6        25.25    -13.48
Divi's Lab               3,150      4174.20        32.5      1,235     1,511.00          22.4    1,015.70  1225.50              20.7        36.20     29.36
                                                                                                                                  OND:Oct-Nov-Dec quarter


Research Desk
Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects
for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s
FOUR-S PharmaHealth Track

          TTM Results
                                                                                                                                                 `in million

                                   Revenue                               EBITDA                               PAT                                  Margins TTM
                 TTM                  TTM                     TTM           TTM                   TTM        TTM                               EBITDA
Companies       Dec 10               Dec 11         YoY      Dec 10        Dec 11        YoY     Dec 10     Dec 11                   YoY         %         NPM %
DR.REDDY'S L     81619                90326          10.7      16824         21710          29.0      11769     14141               20.2         24.0      15.7
RANBAXY LABO     81411                82864           1.8      10305          7052         -31.6       8316         19             -99.8           8.5      0.0
SUN PHARMACE     60315                65947           9.3      18986         22156          16.7      19399     21403               10.3         33.6      32.5
LUPIN LTD        62657                65881           5.1      13064         13827           5.8       9424       9551               1.3         21.0      14.5
CIPLA LTD.       62468                63987           2.4      13564         14274           5.2       9630     10090                4.8         22.3      15.8
CADILA HEALTH    45831                46964           2.5      10466         10388          -0.7       7416       6735              -9.2         22.1      14.3
AUROBINDO PH     45361                44988          -0.8       9937          6687         -32.7       3887       1105             -71.6         14.9       2.5
JUBILANT ORG     37492                39699           5.9       6888          7650          11.1       2714       1651             -39.2         19.3       4.2
GLENMARK PHA     34645                37469           8.2       6580          6270          -4.7       4336       3932              -9.3         16.7      10.5
APOLLO HOSPITAL  24497                25630           4.6       3946          4115           4.3       1937       1999               3.2         16.1       7.8
GLAXOSMITH       22371                22626           1.1       7905          7576          -4.2       4215       4096              -2.8         33.5      18.1
IPCA LAB LTD     20815                22199           6.7       4183          4387           4.9       2622       2621               0.0         19.8      11.8
BIOCON LTD       21614                21689           0.3       5700          5345          -6.2       3564       3427              -3.8         24.6      15.8
OPTO CIRCUIT     18144                20451          12.7       4907          5397          10.0       4016       4457              11.0         26.4      21.8
PIRAMA HEALTH    18517                20055           8.3        -34          -211        517.6        4055       3549             -12.5          -1.1     17.7
ORCHID CHEM      16649                17088           2.6       4123          4447           7.9       1534       1528              -0.4         26.0       8.9
Divi's Lab       15022                16069           7.0       5901          6177           4.7       4850       5059               4.3         38.4      31.5

    OND quarter results not declared for Aurobindo, Apollo, Cipla, Glaxosmith, Orchid,      Standalone results for Cipla, Apollo, Orchid, Glaxosmith, Divis Lab and Ipca Lab
    Ranbaxy and Sun Pharma




               BSE Healthcare Index movement in last 2 weeks




 Research Desk
  Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects
  for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s
FOUR-S PharmaHealth Track


Four-S Services Pvt Ltd
  Founded in 2002, Four-S has a strong & successful track record of genuine, accurate and
  objective advice to top Indian & global companies & PE Firms. Four-S has already proven
  success in corporate finance, strategy consulting, fund-raising, investment banking and
  investor relations mandates with 100+ corporates and large PE funds

Four-S, trusted advisor to top Indian & Global Cos




      Offering comprehensive bouquet of services to Private Equity Funds




Research Desk
Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects
for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s
FOUR-S PharmaHealth Track


                        About Four-S Services
                        Four-S Services provides customized business and financial research to organizations across the
                        globe. The company also provides Investor Relations consulting to corporate based on in-depth
                        sectoral and company research. The company has an impressive client profile and a team of senior
                        analysts covering key sectors including Finance & Banking, IT & Telecom, Retail, Media &
                        Entertainment, Pharmaceuticals, Infrastructure and Manufacturing amongst others. For further
                        information on the company please visit www.four-s.com



                        Disclaimer
                        The information contained herein has been obtained from sources believed to be reliable but is not necessarily complete and its
                        accuracy cannot be guaranteed. No representation, warranty, guarantee or undertaking, express or implied, is made as to the fairness,
                        accuracy or completeness of any information, projections or opinion contained in this document or upon which any such projections or
                        opinions have been based. Four-S Services Pvt Ltd. will not accept any liability, whatsoever with respect to the use of this document or
                        its content. This document has been distributed for information purposes only and does not constitute or form part of any offer or
                        solicitation of any offer to buy or sell any securities. This document shall not form the basis of and should not be relied upon in
                        connection with any contract or commitment whatsoever. This document is not to be reported or copied or made available to others.
                        The Company may from time to time solicit from, or perform consulting, or other services for, any company mentioned in this
                        document.




Research Desk
Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects
for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s

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Four s fortnightly pharma health track 23th january - 5th febuary 2012

  • 1. FOUR-S PharmaHealth Track 23thJan– 5thFeb’11 PharmaHealth TRACK Newsletter on Indian Healthcare Industry Top Story Content Results Update Private Equity 2 Healthcare Pharma sector has seen overall positive results this quarter. Sector has shown strong 28% y-o-y growth in revenue Mergers & Acquisitions 3 for the major companies with results declared till now. Though profit has seen the muted growth this quarter as many companies has seen decrease in net margin q-o-q basis. News Update 4 Dr Reddys Laboratories Q3 net profit at `5129.60 mn Regulatory Developments 6 Drug firm Dr Reddy's Laboratories consolidated net profit rose Upcoming Events 7 by 87.80 per cent to `5129.6mn in the third quarter ended December 31, 2011 vis-a-vis the corresponding year-ago period. The company had posted a net profit of `2731.4mn for Stock Market Update 8 the corresponding period of the previous fiscal. Company's net income from sales and services rose to `27691.9mn in the third Peer Benchmarking 8 quarter ended December 31, 2011, from `18,985.1mn for the same period last fiscal. Company's net income from sales and services rose to `27,691.9mn in the third quarter ended About Four-S Services 10 December 31, 2011, from `18,985.1mn for the same period last fiscal. For the nine months ended December 31, 2011, the company posted a net profit of `10,835mn, compared to `7,695.1mn for the same period last fiscal. About Four-S Services Four-S Services is India's leading provider of Research, Financial Consulting and Investment Banking services with offices in Gurgaon, Mumbai and Bangalore. We have a proven track record of consistently delivering high quality solutions, enabling our clients to improve the effectiveness of decision making and acting as a catalyst in achieving business success. We have executed more than 120 mandates across diverse range of industries including Education, Financial Services, Infrastructure, M&E, IT-ITeS, Auto and Auto ancillaries, Retail, Real Estate and Textile etc Our Services:  Strategy Consulting  Research Support  Business Planning  Valuation Services  Investment Banking  Investor Relations & IPO Consulting For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com Research Desk Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s Top 5 PE Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
  • 2. FOUR-S PharmaHealth Track Investment Activity last 1 year.. Date Investor(s) Target Stake (%) Amount ($mn) Business Stage Aizant Drug Research NA 17-Jan-2011 Zephyr Peacock India 5.0 CRO Early Solutions Ltd Integrated Health & NA 18-Jan-2011 Halcyon Capital Advisor 44.2 Hospitals Buyout Healthcare Services Sequoia Capital, Elevar NA 28-Jan-2011 Glocal Healthcare Systems 3.3 Hospitals Early Equity 15-Apr-2011 Avigo Capital SRL 9.27 224 Diagnostics Growth 5-May-2011 Sabre Partners SRL 4 112 Diagnostics Growth Aquarious India, 17-Jun-2011 Vaatsalya NA 10 Hospitals Growth SeedFund Catamaran, Reliance VA, 20-Jun-2011 Wellspring Healthcare NA 4.6 Hospitals Growth Bluecross BlueShield VP 23-Jun-2011 HDFC PE Angels Health Pvt Ltd 12 0.6 Online Healthcare Early Super specialty 10-Aug-2011 Matrix Partners Kids Clinic NA 10 Early hospital chain 28-Sep-2011 Sequoia Capital Moolchand Medcity NA 22.0 Hospitals Growth Helion Ventures, Nexus 10-Oct-2011 Eye-Q NA NA Hospitals Growth Ventures 28-Nov-2011 Fidelity Growth Partners XCyton Diagnostics NA NA Diagnostics Growth 12-Jan-2012 NEA, DaVita Inc NephroLife Care NA 25.0 Hospitals Growth Sequoia Capital, 11-Jan-2012 Healthkart.Com NA 5.1 Health Services Early Omidyar Network 18-Jan-2012 Olympus Capital DM Healthcare NA 100.0 Hospitals Growth 20-Jan-2012 Songs Investments Be Well Hospitals NA NA Hospitals Growth OrbiMed, Ascent Kerala Institute of Medical 25-Jan-2012 NA 33.3 Hospitals Late Capital Science Source: Four-S Database Four-S Indian PE Directory 2010” – A Guide to choosing private equity partners  Detailed listing of ~330 Active PE/VC Investors in India - PE/VC players that have invested in the past 3 years.  A first-of-its-kind, the directory offers “Deal History” in India for individual investor.  Management, investment profile and Contact details.  User-friendly Spreadsheet Format.  It comes from Four-S Services, the most trusted deal information bank in India. Research Desk Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s Top 5 PE Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
  • 3. FOUR-S PharmaHealth Track Mergers & Acquisition Date Investor(s) Target Stake Amount ($mn) Business (%) 19-Jan 2011 Transasia Bio-Medicals Diasis Diagnostic Systems NA NA Diagnostics 20-Jan 2011 Surya Pharmaceuticals ActivOn NA 22.3 Pharma Bioserve Clinical Research Private 23-Feb-2011 QPS Holdings Limited NA NA Clinical Research 15-Apr-2011 Ecron Ecunova aCROnordic 75% 3.4 CRO 15-Apr-2011 Hikma Pharmaceuticals Unimark Remedies 22.2% 33.3 Pharma 15-Apr-2011 Fortis Healthcare SRL 86% 189.4 Diagnostics 15-Jun-2011 Lupin Goanna Brand NA NA OTC 17-Jun-2011 Zydus Nesher Pharma unit NA NA Generic 19-Jul-2011 Shilpa Medicare Nu Therapeutics 50 NA Pharma 21-Jul-2011 Dr Reddy’s Laboratories JBCL-Russia-CIS prescription products 100 30.5 Pharma 28-Jul-2011 Cadila Healthcare Bremer Pharma 100 NA Pharma 3-Aug-2011 Danone Wockhardt 's nutrition business 100 355 Pharma 9-Aug-2011 Ipca Labs Onyx Research 100 7.5 Healthcare Services 10-Aug-2011 Fortis Hoan My Medical 65 64 Hospitals 12-Sep-2011 Vivimed Labs Octtantis Nobel Labs Ltd 50 NA Pharma 8-Oct-2011 Akorn Inc KilitchDrugs (India) Ltd NA 40.1 Pharma 12-Oct-2011 Life Healthcare Group Max Healthcare Ltd. NA 103.1 Hospitals Universal Medicare - branded Pharma 4-Nov-2011 Aventis Pharma nutraceutical formulations biz NA 114.0 Shalaks Pharmaceuticals - Pharma 14-Nov-2011 Invida Group dermatology and baby care 100 19.1 18-Nov-2011 Lupin Limited I'rom Pharma 100 NA Pharma 24-Nov-2011 SOHM Inc Novatrend Medicament NA NA Pharma Transgene Biotek bio generic product Pharma 23-Nov-2011 TSS EXPORT GmbH FZE - Erythropoietin 100 5.0 28-Nov-2011 Vivimed Labs Uquifa 100 55.0 Pharma 17-Jan-2012 Dishman Pharma Creapharm Parenterals 100 NA Pharma 24-Jan-2012 Watson Pharmaceuticals Ascent Pharma Health Ltd. NA 393 Pharma 1-Feb-2012 Fortis Healthcare RadLink-Asia Pte Ltd 85 50 Diagnostic 2-Feb-2012 Aanjaneya Lifecare Apex Drugs and Intermediaries Ltd 100 50 Pharma Source: Four-S Database Research Desk Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s Top 5 PE Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
  • 4. FOUR-S PharmaHealth Track News Update Healthcare & Pharmaceutical Sector Pfizer posts profit of `482.8mn in Q3 1.) Pharmaceutical Sector Pfizer Ltd reported a net profit of `482.8mn and a net profit of `435.8mn for the third quarter ended December 31, 2011. Net Result Update Continue…. sales of the company stood at `2518.8mn for the third quarter ended December 31, 2011 compared to `2358.4mn for the third Piramal Healthcare Q3 cons net profit at `85.20 mn quarter ended November 30, 2010. For the nine months ended December 31, 2011, the company posted a net profit of Piramal Healthcare Ltd has posted a net profit of `85.20 mn for `1365.1mn compared to `1207.5mn for the third quarter ended the quarter ended December 31, 2011 whereas the same was November 30, 2010. at `603.30 mn for the quarter ended December 31, 2010. Total Income is `6175.70 mn for the quarter ended December 31, TCG Lifesciences completes key milestones on delivery of 2011 whereas the same was at `5348.80 million for the quarter pre-clinical drug candidates ended December 31, 2010. TCG Lifesciences Limited (TCGLS) announced the achievement of For Q3FY2012, Pharma Solutions (CRAMS) business registered two distinct milestones in their ongoing drug discovery strong growth of 57.4% with sales of `3.673bn as compared to partnership with Endo Pharmaceuticals. TCGLS will receive `2.334bn in Q3FY2011. The revenues from Indian facilities grew undisclosed success fees against these milestones. by 68.9 % to `2.24bn. Divis Labs Q3 profit up 20.65 pc at `1225.5mn In the first of two fully integrated discovery programs with Endo aimed at identifying novel small molecule drug candidates for an Drug firm Divis Laboratories net profit rose by 20.65 per cent to unmet medical need, TCGLS has successfully delivered a pre- `1225.5mn for the third quarter ended December 31, 2011 clinical development candidate. In the second, TCGLS has compared to a net profit of `1015.7mn for the quarter ended designed and delivered novel fast-follower hit structures well December 31, 2010. Total income of the company stood at within collaboration timelines. This multi-year, three-stage `4,174.2mn for the quarter ended December 31, 2011 as project aims to identify potent in-vivo active novel blockers of against `3,149.7mn for the corresponding period previous fiscal an undisclosed target for eventual clinical development. Lupin Q3 net up 4.95% at `2351mn Two lead molecules resulting from this collaboration have been selected by Endo for cGMP manufacturing and GLP-toxicology Drug firm Lupin consolidated net profit rose by 4.95 per cent to studies. `2,351mn for the third quarter ended December 31, 2011 compared to net profit of `2240mn for the corresponding Pfizer recalls 1 mn packets of birth control pills period of previous fiscal. Net sales of the company grew by 21.9 per cent to `17,917mn for the third quarter, compared to American pharmaceutical giant Pfizer has announced recall of `14,694mn in the same period previous fiscal. more than one million packets of birth control pills after it found out that inactive or placebo pill may have been placed out-of- Glenmark Pharma Q3 net profit down 46% order in some packs. Company has announced a voluntary recall of Lo/Ovral-28 (norgestrel and ethinyl estradiol) and Norgestrel Glenmark Pharmaceuticals Ltd has posted a net profit after tax and Ethinyl Estradiol Tablets (generic) birth control pills in the of `461.18 million for the quarter ended December 31, 2011 as United States. Its voluntary recall is based on its own internal compared to `865.25 million for the quarter ended December assessments of this problem, in which it found that the inactive 31, 2010. Total Income has increased from `7732.79 million for or placebo pill may have been placed out-of-order in some the quarter ended December 31, 2010 to `10418.45 million for packs. the quarter ended December 31, 2011. The company took a hit of `1.02bn on dollar denominated loans due to rupee State Bank of Mysore files criminal complaint against depreciation. During the quarter, net sales stood at Sterling Biotech for 'repayment dafault' `10,310.8mn as against `7486.4mn in the corresponding period previous fiscal State Bank of Mysore has filed a criminal complaint against Sterling Biotech, and its six directors, for allegedly defaulting on repayments on credit facilities provided by the public sector lender. Research Desk Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s Top 5 PE Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
  • 5. FOUR-S PharmaHealth Track In its complaint, the bank has said that cheques worth 580mn Piramal Group picks up an additional 5.5% stake in submitted by the company have bounced. The cheques were Vodafone India for `30.07bn drawn on Andhra Bank. Sterling Biotech is the flagship company of Gujarat-based Sandesara Group. Sterling Biotech has 7.5% Piramal Healthcare Ltd would buy a 5.5 per cent stake in stake in the world gelatin market and has 60% share in the local Vodafone's India unit, Essar, for `30.07bn ($616.14 million), market. taking its total stake in the mobile company to about 11 per cent. Indoco Remedies signs strategic pact with DSM Pharma The sale would mark the exit of Essar as Vodafone's joint Indoco Remedies Ltd. has entered into a strategic business venture partner in India after the London-listed company last alliance with DSM Pharmaceutical Products NV. DSM year sealed a long awaited deal to buy out Essar in July. Pharmaceutical Products NV is a constituent of the Royal DSM Vodafone last year bought 22 per cent of Essar and Piramal NV, Austria. bought 5.5 per cent. Under the agreement reached, DPP will market and sell eight The transaction contemplates various exit options for Piramal, active pharma ingredients (APIs) manufactured by Indoco in including both participation in a potential IPO of the unit and a Austria and other international markets. sale of its stake back to Vodafone Fondaparinux injection issue resolved with USFDA: Dr 2.) Healthcare Reddy's Laboratories Fortis Healthcare arm acquires 85% stake in RadLink-Asia Drug firm Dr Reddy's Laboratories has resolved all issues raised by a division of US health regulator over its promotional Fortis Healthcare Singapore Pte, Fortis Healthcare India offshore material for an anti-coagulant injection. subsidiary, has acquired 85% stake in RadLink-Asia Pte Ltd ("RadLink"), an outpatient diagnostic and molecular imaging Office of Prescription Drug Promotion (OPDP) had issued a letter chain in Singapore, for a purchase consideration of S$62.9 to the company for changes related to certain promotional million. material for Fondaparinux Sodium for Injection. The company has already addressed all matters raised by the Division of The transaction provides Fortis Healthcare a strong foothold in Professional Promotion (DPP), USFDA in the letter issued on the premium diagnostics and molecular imaging segment in one January 10, 2012. The DPP informed Dr Reddy's Lab on January of Southeast Asia's most attractive markets besides providing a 24, 2012 that the matters are now considered closed. complementary platform to its upcoming specialty hospital on Adam Road in Singapore. OPDP through the letter had intimated to the Hyderabad- based drug firm that the company's information on a promotional Radlink has four main business segments; diagnostic imaging, website for Fondaparinux Sodium Solution for subcutaneous molecular imaging, cyclotron (radio-isotopes manufacturing) injection was misleading. and GP clinics. US drugmaker Eli Lilly, Jubilant Life call off joint venture Fortis Healthcare invests SGD70 million in 2 Singapore healthcare ventures US drugmaker Eli Lilly & Company and Noida-based Jubilant Life Sciences have called off their equal drug-discovery Indian healthcare group Fortis is investing SGD 70 million (about partnership to develop molecules across several therapeutic `2.74bn) in two colorectal centres in Singapore this year. Fortis areas. Healthcare Singapore had opened a outpatient clinic for colorectal diseases, Novena Colorectal Centre, and a 31- The 50:50 JV, formed in late 2008 between Jubilant Life bed Fortis Hospital for Colorectal Diseases in June this year. Sciences' wholly-owned subsidiary Jubilant Biosys and Lilly, was Fortis has started hiring nurses and allied health professionals to develop molecules from the pre-clinical to phase II stage for 80 positions at the clinic and hospital. The hospital would across oncology, diabetes and cardiovascular segments. The firm serve 40 patients a day while the clinic would be a group is called Vanthys Pharmaceuticals and based in Bangalore. practice by four colorectal specialists who also have deeper expertise in areas such as robotic surgery to genetic testing. Research Desk Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s Top 5 PE Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
  • 6. FOUR-S PharmaHealth Track Fortis to raise US$300mn via IPO of non-core biz written records, not prevented contamination of sterile drugs at its facilities, inadequately tested drugs, and submitted false data Fortis Healthcare (India) is planning to raise $300 mn by spinning to the FDA. The company made adulterated and potentially off its non-core business into a separate company, which will unsafe drugs that were illegal to sell, it claimed. then be listed on the Singapore Stock Exchange. Hospitals operator Fortis, controlled by billionare brothers Malvinder and Shivinder Singh, expects the restructuring to be completed by Global News Update the middle of next month. Valeant gives up on bid to buy Ista The initial public offering is likely to hit the market in May or Valeant Pharmaceuticals International, pharmaceutical June this year. company, headquartered in Canada, has withdrawn its offer to acquire Ista Pharmaceuticals, a US based pharmaceutical 3.) Regulations/Legal company that specializes in ophthalmic pharmaceutical products, a fortnight after upping its bid for the eye specialist. Orchid Pharma receives USFDA nod for Levofloxacin Tabs ANDA Just before Christmas, Valeant's $6.50 per share offer, which valued Ista at $314 million, was dismissed as "grossly The Chennai-based global pharma major, Orchid Chemicals & inadequate" by the latter. However, Valeant then raised its Pharmaceuticals Ltd has received approval from the US FDA for initial proposal to $7.50 per share in cash and set a target price its ANDA (Abbreviated New Drug Application) for Levofloxacin of $8.50 per share in cash, subject to one week of due diligence. Tablets in the 250 mg, 500 mg and 750 mg strengths. Amgen hits acquisition trail to snap up Micromet as profits slip Lupin gets USFDA approval for diabetes drug Amgen, a international biotechnology company, headquartered Drug firm Lupin has received approval from the US health in California, has opened its wallet and unveiled plans to buy regulator for its Metformin Hydrochloride Extended Release Micromet, a biotech with its R&D centre in Munich and tablets, used in treating diabetes. The company's US-based headquarters in Rockville, USA, for $1.16 billion. subsidiary Lupin Pharmaceuticals Inc has received tentative approval from US Food and Drug Administration (USFDA) for Amgen is offering $11 per share in cash, and the acquisition Metformin tablets in strengths of 500 mg and 1,000 mg. Lupin's includes blinatumomab, a bispecific T cell engager (BiTE) Metformin HCl ER Tablets are the AB-rated generic equivalent of antibody in Phase II for acute lymphoblastic leukaemia. The drug Santarus Inc's Glumetza HCl ER Tablets. According to IMS is also in studies for non-Hodgkin's lymphoma. Health data, Glumetza HCl ER tablets in strengths of 500 mg and 1,000 mg had annual US sales of nearly USD 58 million for the 12 The companies already have a partnership in place. In July last months to September, 2011. year, they signed a deal involving the development of BiTE antibodies against three undisclosed solid tumour targets. Ranbaxy settles row with USFDA; to upgrade plants in India and US Micromet's pipeline includes solitomab, a BiTE antibody in Ranbaxy Laboratories has agreed to make significant changes in Phase I for advanced solid tumours. Amgen will also be entitled its manufacturing facilities in India and the US as part of a to milestone and royalties from the company's existing licensees settlement that seeks to end wide-ranging investigations against of BiTE (such as Sanofi, AstraZeneca, Boehringer Ingelheim and the drug maker by the US regulatory authorities. Bayer) and other technologies. A consent decree, signed between Ranbaxy and the US Food Celgene to acquire Avila and Drug Administration (FDA) last month and filed in a US court Celgene Corp, a manufacturer of drug therapies for cancer and on Wednesday, extends the ban on supply of drugs from four inflammatory disorders, headquartered in New Jersey, is to plants to the US market until the Indian drug maker resolves the acquire privately-held Avila Therapeutics in a deal that could be problems at these facilities, dashing hopes of the embargo being worth up to $925 million. lifted immediately after the settlement. Celgene is paying $350 million in cash, plus up to $195 million The US Department of Justice (DoJ), which filed the consent for milestones related to the progress of AVL-292, an oral decree at the request of the FDA, said Ranbaxy had not kept Research Desk Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s Top 5 PE Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
  • 7. FOUR-S PharmaHealth Track covalent drug that inhibits Bruton’s tyrosine kinase which stockholder rights agreement, which is "designed to deter currently in Phase I for non-Hodgkin’s lymphoma, B cell chronic coercive or otherwise unfair takeover tactics". Earlier this week, lympocytic leukaemia and rheumatoid arthritis. the Swiss major, having been rebuffed by Illumina's board a number of times over the last month, made an unsolicited offer The deal also includes up to $380 million in potential milestone of $44.50 a share in cash, which represents a premium of about payments contingent upon the development and approval of 18% to Illumina's stock price on January 24. candidates generated from Avila's Avilomics platform. The rights agreement means that Illumina shareholders can buy Illumina adopts 'poison pill' to deter Roche approach $550 in common shares for just $275 if a bidder acquires 15% of the company’s stock. The effect of this would be make Illumina Illumina is adopting a 'poison pill' in a bid to block Roche’s $5.7 more expensive to acquire. billion hostile takeover offer. The US company, which develops tools and systems for the analysis of genetic variation and function, has announced a Events Calendar India Pharma Convention BioAsia 2012: The Global Biobusiness Forum Date: Feb 12, 2012 Date: 9 Feb 12 – 11 Feb 2012 Venue: DIPSAR, Delhi Venue: Hyderabad International Convention Centre, Hyderabad Organizer: BioAsia Organizer: Udyog Development Foundation Tel: 91 – 40 – 66446477 website: www.udfoundation.com E-mail: info@bioasia.in Medical Fair India PHARMA Pro&Pack 2013 Date: 2 Mar-4 Mar, 2012 Date: Apr 24-26, 2012 Venue: Bombay exhibition center, Mumbai Venue: Mumbai exhibition center, Goregaon, Mumbai Webmail: http://ems2012.in/ Website: http://www.pharmapropack.com Organizer : Messe Duesseldorf Email: contact@pharmapropack.com http://www.medicalfair-india.com/ Research Desk Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s Top 5 PE Funds. For further information, please contact Seema Shukla at seema@four-s.com or reach us as http://www.four-s.com
  • 8. FOUR-S PharmaHealth Track Stock Market Update As on 21 Jan 2012 Market Cap Price Percentage Change (%) In `Mn In ` 1W 1M 3M 6M 1 Year SUN PHARMACE 547616 529 2.89 5.62 8.13 5.23 8.28 DR.REDDY'S L 287598 1696 -0.64 4.74 8.05 4.97 -1.63 CIPLA LTD. 266409 332 -0.70 2.09 16.08 5.76 -4.35 LUPIN LTD 197597 442 2.62 3.15 -6.22 -4.63 -5.05 RANBAXY LABO 195380 463 0.84 18.39 -6.65 -12.90 -17.01 GLAXOSMITH 166645 1967 0.13 6.42 -6.40 -14.76 -13.40 CADILA HEALTH 133844 654 -3.64 -8.16 -13.70 -26.20 -21.57 DIVI's LAB 103787 782 -0.22 5.27 7.16 -5.62 24.01 GLENMARK PHA 86251 319 1.55 13.82 9.99 1.54 0.02 APOLLO HOSPITAL 84015 625 -3.55 15.35 17.83 22.32 27.13 PIRAMA HEALTH 71786 416 0.59 12.31 16.50 3.44 -9.66 BIOCON LTD 54980 275 1.76 5.98 -21.81 -26.86 -26.65 OPTO CIRCUIT 41576 223 9.03 27.25 -4.06 -15.20 -9.65 IPCA LAB LTD 35016 279 1.22 10.91 13.60 -16.88 -14.08 JUBILANT ORG 28798 181 -4.05 7.98 -9.40 -18.47 -28.51 AUROBINDO PH 28195 97 -6.71 12.73 -20.27 -41.97 -60.26 ORCHID CHEM 10785 153 7.07 24.21 0.52 -32.13 -48.87 BSE SENSEX 17,605 2.2 10.5 0.7 -1.9 -4.6 NSE NIFTY 15,695 -4.1 -9.0 -2.8 -12.1 -18.8 BSE HEALTHCARE 5,326 2.3 11.8 1.1 -1.5 -3.6 Quarterly Results `in million Companies Revenue EBITDA PAT Margins JAS’ OND’ OND’ YoY OND’ OND’ YoY OND’ OND’ YoY EBITDA% NPM % FY10 FY11 FY10 FY11 FY10 FY11 FY’11 FY’11 DR.REDDY'S L 18985.10 27691.90 45.9 3801.70 8688.20 128.5 2731.40 5129.60 87.8 31.37 18.52 RANBAXY LABO 19283.60 20955.31 8.7 2483.89 -769.17 -131.0 3079.36 -4645.80 -250.9 -3.67 -22.17 SUN PHARMACE 13314.20 18946.00 42.3 4670.40 7840.40 67.9 5036.50 5977.40 18.7 41.38 31.55 LUPIN LTD 15102.10 18189.30 20.4 2972.60 3735.00 25.6 2240.30 2350.60 4.9 20.53 12.92 CIPLA LTD. 16343.90 17780.20 8.8 3665.60 4376.10 19.4 2630.10 3089.70 17.5 24.61 17.38 CADILA HEALTH 11668.10 13832.20 18.5 2561.70 2615.90 2.1 1620.10 1492.10 -7.9 18.91 10.79 JUBILANT ORG 8689.70 10884.90 25.3 1321.50 2083.90 57.7 441.10 -783.90 -277.7 19.14 -7.20 AUROBINDO PH 11126.20 10753.00 -3.4 2542.20 -707.90 -127.8 1983.20 -801.60 -140.4 -6.58 -7.45 GLENMARK PHA 7491.41 10313.12 37.7 1338.91 1028.65 -23.2 865.25 461.18 -46.7 9.97 4.47 APOLLO HOSP 5864.00 6997.50 19.3 996.00 1165.00 17.0 495.50 557.60 12.5 16.65 7.97 IPCA LAB LTD 4663.60 6148.30 31.8 909.90 1113.90 22.4 639.50 639.30 0.0 18.12 10.40 GLAXOSMITH 5892.70 6146.20 4.3 2159.60 1830.40 -15.2 1578.10 1458.60 -7.6 29.78 23.73 OPTO CIRCUIT 4176.60 6112.94 46.4 1228.18 1710.36 39.3 956.75 1250.85 30.7 27.98 20.46 PIRAMA HEALTH 4026.90 5587.00 38.7 -325.60 -502.10 54.2 603.30 85.20 -85.9 -8.99 1.52 BIOCON LTD 5113.80 5185.10 1.4 1642.40 1287.20 -21.6 1007.60 848.50 -15.8 24.82 16.36 ORCHID CHEM 3817.97 4194.92 9.9 734.77 1059.09 44.1 240.15 -565.68 -335.6 25.25 -13.48 Divi's Lab 3,150 4174.20 32.5 1,235 1,511.00 22.4 1,015.70 1225.50 20.7 36.20 29.36 OND:Oct-Nov-Dec quarter Research Desk Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s
  • 9. FOUR-S PharmaHealth Track TTM Results `in million Revenue EBITDA PAT Margins TTM TTM TTM TTM TTM TTM TTM EBITDA Companies Dec 10 Dec 11 YoY Dec 10 Dec 11 YoY Dec 10 Dec 11 YoY % NPM % DR.REDDY'S L 81619 90326 10.7 16824 21710 29.0 11769 14141 20.2 24.0 15.7 RANBAXY LABO 81411 82864 1.8 10305 7052 -31.6 8316 19 -99.8 8.5 0.0 SUN PHARMACE 60315 65947 9.3 18986 22156 16.7 19399 21403 10.3 33.6 32.5 LUPIN LTD 62657 65881 5.1 13064 13827 5.8 9424 9551 1.3 21.0 14.5 CIPLA LTD. 62468 63987 2.4 13564 14274 5.2 9630 10090 4.8 22.3 15.8 CADILA HEALTH 45831 46964 2.5 10466 10388 -0.7 7416 6735 -9.2 22.1 14.3 AUROBINDO PH 45361 44988 -0.8 9937 6687 -32.7 3887 1105 -71.6 14.9 2.5 JUBILANT ORG 37492 39699 5.9 6888 7650 11.1 2714 1651 -39.2 19.3 4.2 GLENMARK PHA 34645 37469 8.2 6580 6270 -4.7 4336 3932 -9.3 16.7 10.5 APOLLO HOSPITAL 24497 25630 4.6 3946 4115 4.3 1937 1999 3.2 16.1 7.8 GLAXOSMITH 22371 22626 1.1 7905 7576 -4.2 4215 4096 -2.8 33.5 18.1 IPCA LAB LTD 20815 22199 6.7 4183 4387 4.9 2622 2621 0.0 19.8 11.8 BIOCON LTD 21614 21689 0.3 5700 5345 -6.2 3564 3427 -3.8 24.6 15.8 OPTO CIRCUIT 18144 20451 12.7 4907 5397 10.0 4016 4457 11.0 26.4 21.8 PIRAMA HEALTH 18517 20055 8.3 -34 -211 517.6 4055 3549 -12.5 -1.1 17.7 ORCHID CHEM 16649 17088 2.6 4123 4447 7.9 1534 1528 -0.4 26.0 8.9 Divi's Lab 15022 16069 7.0 5901 6177 4.7 4850 5059 4.3 38.4 31.5 OND quarter results not declared for Aurobindo, Apollo, Cipla, Glaxosmith, Orchid, Standalone results for Cipla, Apollo, Orchid, Glaxosmith, Divis Lab and Ipca Lab Ranbaxy and Sun Pharma BSE Healthcare Index movement in last 2 weeks Research Desk Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s
  • 10. FOUR-S PharmaHealth Track Four-S Services Pvt Ltd Founded in 2002, Four-S has a strong & successful track record of genuine, accurate and objective advice to top Indian & global companies & PE Firms. Four-S has already proven success in corporate finance, strategy consulting, fund-raising, investment banking and investor relations mandates with 100+ corporates and large PE funds Four-S, trusted advisor to top Indian & Global Cos Offering comprehensive bouquet of services to Private Equity Funds Research Desk Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s
  • 11. FOUR-S PharmaHealth Track About Four-S Services Four-S Services provides customized business and financial research to organizations across the globe. The company also provides Investor Relations consulting to corporate based on in-depth sectoral and company research. The company has an impressive client profile and a team of senior analysts covering key sectors including Finance & Banking, IT & Telecom, Retail, Media & Entertainment, Pharmaceuticals, Infrastructure and Manufacturing amongst others. For further information on the company please visit www.four-s.com Disclaimer The information contained herein has been obtained from sources believed to be reliable but is not necessarily complete and its accuracy cannot be guaranteed. No representation, warranty, guarantee or undertaking, express or implied, is made as to the fairness, accuracy or completeness of any information, projections or opinion contained in this document or upon which any such projections or opinions have been based. Four-S Services Pvt Ltd. will not accept any liability, whatsoever with respect to the use of this document or its content. This document has been distributed for information purposes only and does not constitute or form part of any offer or solicitation of any offer to buy or sell any securities. This document shall not form the basis of and should not be relied upon in connection with any contract or commitment whatsoever. This document is not to be reported or copied or made available to others. The Company may from time to time solicit from, or perform consulting, or other services for, any company mentioned in this document. Research Desk Four-S Services is India's leading provider of high-end research, financial consulting and Investment banking services. We have executed projects for prestigious Indian as well as global corporations, investment banks, private equity funds, venture capitalists and hedge funds including India’s