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1. National Cancer Institute at the National Institutes of Health
Updated: 03/10/2014
Drugs Approved for Leukemia
This page lists cancer drugs approved by the Food and Drug Administration (FDA) for leukemia. The
list includes generic and brand names. This page also lists common drug combinations used in
leukemia. The individual drugs in the combinations are FDA-approved. However, drug combinations
themselves usually are not approved, but are widely used.
The drug names link to NCI's Cancer Drug Information summaries. There may be drugs used in
leukemia that are not listed here.
On this page:
Drugs Approved for Acute Lymphoblastic Leukemia (ALL)
Drugs Approved for Acute Myeloid Leukemia (AML)
Drugs Approved for Chronic Lymphocytic Leukemia (CLL)
Drugs Approved for Chronic Myelogenous Leukemia (CML)
Drugs Approved for Meningeal Leukemia
Drugs Approved for Acute Lymphoblastic Leukemia (ALL)
Abitrexate (Methotrexate)
Adriamycin PFS (Doxorubicin Hydrochloride)
Adriamycin RDF (Doxorubicin Hydrochloride)
Arranon (Nelarabine)
Asparaginase Erwinia chrysanthemi
Cerubidine (Daunorubicin Hydrochloride)
Clafen (Cyclophosphamide)
Clofarabine
Clofarex (Clofarabine)
Clolar (Clofarabine)
Cyclophosphamide
Cytarabine
Cancer Drug Information
Page 1 of 4Drugs Approved for Leukemia - National Cancer Institute
5/11/2014http://www.cancer.gov/cancertopics/druginfo/leukemia/print

2. Cytosar-U (Cytarabine)
Cytoxan (Cyclophosphamide)
Dasatinib
Daunorubicin Hydrochloride
Doxorubicin Hydrochloride
Erwinaze (Asparaginase Erwinia Chrysanthemi)
Folex (Methotrexate)
Folex PFS (Methotrexate)
Gleevec (Imatinib Mesylate)
Iclusig (Ponatinib Hydrochloride)
Imatinib Mesylate
Marqibo (Vincristine Sulfate Liposome)
Mercaptopurine
Methotrexate
Methotrexate LPF (Methorexate)
Mexate (Methotrexate)
Mexate-AQ (Methotrexate)
Nelarabine
Neosar (Cyclophosphamide)
Oncaspar (Pegaspargase)
Pegaspargase
Purinethol (Mercaptopurine)
Purixan (Mercaptopurine)
Rubidomycin (Daunorubicin Hydrochloride)
Sprycel (Dasatinib)
Tarabine PFS (Cytarabine)
Vincasar PFS (Vincristine Sulfate)
Vincristine Sulfate
Vincristine Sulfate Liposome
Drug Combinations Used in Acute Lymphoblastic Leukemia (ALL)
Hyper-CVAD
Drugs Approved for Acute Myeloid Leukemia (AML)
Adriamycin PFS (Doxorubicin Hydrochloride)
Adriamycin RDF (Doxorubicin Hydrochloride)
Arsenic Trioxide
Cerubidine (Daunorubicin Hydrochloride)
Clafen (Cyclophosphamide)
Cyclophosphamide
Cytarabine
Page 2 of 4Drugs Approved for Leukemia - National Cancer Institute
5/11/2014http://www.cancer.gov/cancertopics/druginfo/leukemia/print

3. Cytosar-U (Cytarabine)
Cytoxan (Cyclophosphamide)
Daunorubicin Hydrochloride
Doxorubicin Hydrochloride
Neosar (Cyclophosphamide)
Rubidomycin (Daunorubicin Hydrochloride)
Tarabine PFS (Cytarabine)
Trisenox (Arsenic Trioxide)
Vincasar PFS (Vincristine Sulfate)
Vincristine Sulfate
Drug Combinations Used in Acute Myeloid Leukemia (AML)
ADE
Drugs Approved for Chronic Lymphocytic Leukemia (CLL)
Alemtuzumab
Ambochlorin (Chlorambucil)
Amboclorin (Chlorambucil)
Arzerra (Ofatumumab)
Bendamustine Hydrochloride
Campath (Alemtuzumab)
Chlorambucil
Clafen (Cyclophosphamide)
Cyclophosphamide
Cytoxan (Cyclophosphamide)
Fludara (Fludarabine Phosphate)
Fludarabine Phosphate
Gazyva (Obinutuzumab)
Ibrutinib
Imbruvica (Ibrutinib)
Leukeran (Chlorambucil)
Linfolizin (Chlorambucil)
Neosar (Cyclophosphamide)
Obinutuzumab
Ofatumumab
Treanda (Bendamustine Hydrochloride)
Drug Combinations Used in Chronic Lymphocytic Leukemia (CLL)
CHLORAMBUCIL-PREDNISONE
Page 3 of 4Drugs Approved for Leukemia - National Cancer Institute
5/11/2014http://www.cancer.gov/cancertopics/druginfo/leukemia/print

4. CVP
Drugs Approved for Chronic Myelogenous Leukemia (CML)
Bosulif (Bosutinib)
Bosutinib
Busulfan
Busulfex (Busulfan)
Clafen (Cyclophosphamide)
Cyclophosphamide
Cytarabine
Cytosar-U (Cytarabine)
Cytoxan (Cyclophosphamide)
Dasatinib
Gleevec (Imatinib Mesylate)
Iclusig (Ponatinib Hydrochloride)
Imatinib Mesylate
Myleran (Busulfan)
Neosar (Cyclophosphamide)
Nilotinib
Omacetaxine Mepesuccinate
Ponatinib Hydrochloride
Sprycel (Dasatinib)
Synribo (Omacetaxine Mepesuccinate)
Tarabine PFS (Cytarabine)
Tasigna (Nilotinib)
Drugs Approved for Meningeal Leukemia
Cytarabine
Cytosar-U (Cytarabine)
Tarabine PFS (Cytarabine)
Page 4 of 4Drugs Approved for Leukemia - National Cancer Institute
5/11/2014http://www.cancer.gov/cancertopics/druginfo/leukemia/print