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2300 Sepsis Project
Systemic Inflammatory Response - SIRS ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Severe Sepsis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Septic Shock ,[object Object],[object Object],[object Object]
How Sepsis Progresses
Complex clinical picture… ,[object Object],[object Object],[object Object],[object Object]
Common sources of infection Wounds UTIs Pneumonia
Immediate Management ,[object Object],[object Object],[object Object],[object Object],[object Object]
Immediate Management ,[object Object],[object Object],[object Object],[object Object],[object Object]
Adult Septic Shock Protocol ,[object Object],[object Object],[object Object]
Adult Septic Shock Protocol ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Adult Septic Shock Protocol ,[object Object],[object Object],[object Object],[object Object]
Adult Septic Shock Protocol ,[object Object],[object Object]
Adult Septic Shock Protocol ,[object Object],[object Object],[object Object]
Adult Septic Shock Protocol ,[object Object],[object Object]
Adult Septic Shock Protocol ,[object Object],[object Object]
Adult Septic Shock Protocol ,[object Object],[object Object]
Adult Septic Shock Protocol ,[object Object]
Adult Septic Shock Protocol ,[object Object],[object Object]
Adult Septic Shock Protocol ,[object Object],[object Object],[object Object],[object Object],[object Object]
Central and Mixed Venous Saturation
Venous O2 Saturation… ,[object Object],[object Object]
Venous Saturation depends on … ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Saturation of arterial blood is 100% ,[object Object],[object Object],[object Object]
The patient is HYPOXIC… ,[object Object],[object Object],[object Object],[object Object],[object Object]
The patient is SEPTIC … ,[object Object],[object Object],[object Object],[object Object]
SvO2 less than 50% indicates anaerobic metabolism and development of  acidosis
Where is the best place to get venous blood to measure venous saturation? ,[object Object],[object Object]
If the SaO2 drops due to suctioning  or the development of ARDS,  what do you expect to happen  to the SvO2?
If the SaO2 drops due to suctioning  or the development of ARDS,  what do you expect to happen  to the SvO2? You would expect it to drop 88% - 25% = 63%
If you gave your patient a fluid bolus that they really needed (CVP 0,  CI 1.8), what would you expect to happen to the SvO2?
If you gave your patient a fluid bolus  that they really needed (CVP 0, CI 1.8), what would you expect to happen to the SvO2? Expect it to increase (if it’s low) or remain normal because the increase in CO means the tissues don’t need to extract more O2 than normal
SvO2  extraction SvO2 75% (65 – 77) SvO2 extraction delivery demand delivery demand Hypothermia Sepsis Anesthesia Neuromuscular blockade ,[object Object],[object Object]
Assess for the cause of  SvO2 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
That’s all for now! ,[object Object],[object Object]

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2300 sepsis project

  • 2.
  • 3.
  • 4.
  • 6.
  • 7. Common sources of infection Wounds UTIs Pneumonia
  • 8.
  • 9.
  • 10.
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.
  • 21. Central and Mixed Venous Saturation
  • 22.
  • 23.
  • 24.
  • 25.
  • 26.
  • 27. SvO2 less than 50% indicates anaerobic metabolism and development of acidosis
  • 28.
  • 29. If the SaO2 drops due to suctioning or the development of ARDS, what do you expect to happen to the SvO2?
  • 30. If the SaO2 drops due to suctioning or the development of ARDS, what do you expect to happen to the SvO2? You would expect it to drop 88% - 25% = 63%
  • 31. If you gave your patient a fluid bolus that they really needed (CVP 0, CI 1.8), what would you expect to happen to the SvO2?
  • 32. If you gave your patient a fluid bolus that they really needed (CVP 0, CI 1.8), what would you expect to happen to the SvO2? Expect it to increase (if it’s low) or remain normal because the increase in CO means the tissues don’t need to extract more O2 than normal
  • 33.
  • 34.
  • 35.