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1. HERBAL HILLS
DIABOHILLS (Karela Jamun) JUICE
Diabetes Management

2. Product Description
Herbal Hills Diabohills (Karela-Jamun Juice)
Ingredient : Jambu, Karela, Guduchi, Baheda, Harde, Sunthee, Amla,
Turmeric, Neem, Fenugreek, Gurmar, Ashwagandha, Kadu Chirayati, Shatavari
Diabohills juice with a potent combination of Bitter Gourd &
Jambu which helps to maintain healthy blood sugar levels.
Bitter Gourd is very low in calories, rich in phyto-nutrients like
dietary fiber, minerals, vitamins and anti-oxidants. Bitter Gourd
notably contains phyto-nutrient, polypeptide-P. In addition it
also contains hypoglycemic agent called charantin which may
help to increase glucose uptake and glycogen synthesis in the
cells of liver, muscle and adipose tissue. Jamun (Java Plum) :
Jamun is a rich source of vitamin A and vitamin C. This fruit
contains a large number of minerals and provide fewer
calories.
Directions: Take 30 ml Juice mixed with 100 ml water or fruit
juice or have it plain
Caution : Pregnant or lactating women are
advised to consume herbal products under the
advice of the Physician.
Presentation 500 ml
Juice, available in
Pet bottle
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3.  What is Herbal Hills Diabohills (Karela Jamun) Juice ?
•
•
It is a quality product containing EUGENIA JMABOLANA + MOMORDICA
CHARANTIA as its ingredient.
Vernacular Name: Jambu & Karela or Bitter Gourd
Part Used for Juice : Pulp OF Jamun & fruit of Karela

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Dietary Fibers
Vitamins
Minerals
Antioxidants
Phyto-nutrient (polypeptide-P)
Charantin
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4.  Why Diabohills (Karela-Jamun) Juice?
Diabohills juice with a potent combination of Bitter Gourd & Jambu with varioys
herbs, helps to maintain healthy blood sugar levels.
 Jambu in Diabohills Juice is very effective in non insulin dependent diabetes. It also
helps in reducing fasting blood sugar too.
 Karela : It has blood sugar lowering action of the freshly extracted juice or the pulp. It
not only controls sugar levels but also helps in reviving pancreatic beta cells which
make insulin in our body.
 Guduchi helps to reduce and bring back the blood sugar to normal level. The root
extract also causes an increase in the levels of glutathione and vitamin C in alloxan
diabetes in combating free radicals.
 Baheda acts as an astringent .It acts as a detoxifier It is useful in anaemia and
leucoderma.
 Harde helps in improving glucose tolerance. helps carbohydrate metabolism,Acts as a
bowel cleanser.Harde also promotes wound healing in diabetes.
 Sunthee has anti diabetic and hypolipidemic property. It attenuate structural
nephropathy progression in diabetes.
 Amla : The extract of amla also has antimicrobial properties.

5.  Why Diabohills (Karela-Jamun) Juice?
Diabohills juice with a potent combination of Bitter Gourd & Jambu with varioys
herbs, helps to maintain healthy blood sugar levels.
 Turmeric : In Diabetes, Curcumin of Curcuma longa have been very effective in
bringing down the sugar levels and also help in cleansing the blood & keeping the
cholesterol under control.
Neem : It has anti diabetic properties and helps improve blood circulation, thus being
effective in neuropathy.
Fenugreek has anti diabetic, anti hyper lipidemic activity. It helps in reducing weight, useful
in acidity, constipation etc.
Gurmar is the most effective herbal treatment for diabetes.
Ashwagandha roots are astringent, somniferous, stimulant, aphrodisiac, diuretic,
thermogenic and tonic.
 Kadu chirayata helps in strengthening the stomach and promoting its action.It possesses
anthelmintic property and exhibits toning effect on liver and pancreas.
 Shatavari (Asparagus racemosus) acts as a Rasayana, a dietary supplement or promotes
rejuvenation, mental and physical health.

6. Technical Explanation
of
Dibohills (Karela-Jamun) with
References
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7. 1) PHYTOCONSTITUENTS of Karela….
•
•
Major plant: glucoside, saponin (charantin- 0.5% charantin.) aromatic volatile
oil, 7% bitter principles .
Fruits and leaves: momordicine, ascorbigen, aspartic acid, serine, glutamic
acid, threonine, alanine, g-amino butyric acid and pipecolic acid.
momorcharasides, momorcharins, momordenol, momordicilin
2) PHARMOCOLOGICAL PROPERTIES of Karela….
•
•
Antidiabetic,
Hypoglycemic,
Antibiotic,
Antimutagenic,
Antioxidant,
Antileukemic, Astringent, Bitter tonic. Carminative, Cytotoxic, Depurative,
Hypotensive, Immunomodulatory, Purgative, Refrigerant, Stomachic, Styptic,
Tonic, Vermifuge.
Bitter Melon have all been used, the fruit is the safest and most prevalent part
of the plant used medicinally. The leaves and fruit have both been used
occasionally to make teas and beer, or to season soups in the Western world.
Bitter Melon was traditionally used for many conditions by people in tropical
regions. Numerous infections, cancer, leukemia, and diabetes are among the
most common conditions it was believed to improve. Bitter Melon is reported
to help in the treatment of diabetes and psoriasis.
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8. 3) REFERENCES ….
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Effects of Momordica charantia fruit juice on islet morphology in the pancreas of the
streptozotocin-diabetic rat. Ahmed, E Adeghate, A.K Sharma, D.J Pallot, J Singh
Diabetes Research and Clinical Practice, Vol 40, (3), Pages 145-151, 1998
Hypotriglyceridemic and hypocholesterolemic effects of anti-diabetic Momordica
charantia (Karela) fruit extract in streptozotocin-induced diabetic rats Ahmed I,
Lakhani MS, Gillett M, John A, Raza H. Diabetes Res Clin Pract. 2001 Mar;
51(3):155-61.
The effect of. Momordica charantia capsule preparation on glycemic control in type 2
diabetes mellitus needs further studies Dans AM, Villarruz MV, Jimeno CA,
Javelosa MA, et al. J Clin Epidemiol. 2007 Jun; 60(6):554-9.
Effect of Momordica charantia on the glucose tolerance in maturity onset diabetes.
Welihinda J, Karunanayake EH, Sheriff MH, Jayasinghe KS. J Ethnopharmacol
1986 Sep; 17(3):277-82
Suppressive activity of the fruit of Momordica charantia with exercise on blood
glucose in type 2 diabetic mice. Miura T, Itoh Y, Iwamoto N, Kato M, Ishida T.Biol
Pharm Bull. 2004 Feb; 27(2):248-50
The effect of topical extract of Momordica charantia (bitter gourd) on wound healing
n nondiabetic rats and in rats with diabetes induced by streptozotocin. Teoh SL,
Latiff AA, Das S.: Clin Exp Dermatol. 2009 Mar 23. (Ahead of Print)
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9. •
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Demonstration of the hypoglycemic action of Momordica charantia in a validated
animal model of diabetes. Sarkar S, Pranava M, Marita R Pharmacol Res. 1996
Jan; 33(1):1-4
Hypoglycaemic activity of saponin fraction extracted from Momordica charantia in
PEG/salt aqueous two-phase systems.Han C, Hui Q, Wang Y. Nat Prod Res. 2008;
22(13):1112-9.
Effects of alcoholic extract of Momordica charantia (Linn.) whole fruit powder on the
pancreatic islets of alloxan diabetic albino rats. Singh N, Gupta M, Sirohi P, Varsha. ;
J Environ Biol. 2008 Jan; 29(1):101-6.
A cell-based screening identifies compounds from the stem of Momordica charantia
that overcome insulin resistance and activate AMP-activated protein kinase.Cheng
HL, Huang HK, Chang CI, Tsai CP, Chou CH. J Agric Food Chem. 2008 Aug 27;
56(16):6835-43.
Antidiabetic activities of triterpenoids isolated from bitter melon associated with
activation of the AMPK pathway.Tan MJ, Ye JM, Turner N, Hohnen-Behrens C, Ke
CQ, et al Chem Biol. 2008 Mar; 15(3):263-73
An experimental evaluation of the antidiabetic and antilipidemic properties of a
standardized Momordica charantia fruit extract. Fernandes NP, Lagishetty CV, Panda
VS, Naik SR. BMC Complement Altern Med. 2007 Sep 24; 7:29.
Hypoglycaemic and hypotensive effects of Momordica charantia Linn
(Cucurbitaceae) whole-plant aqueous extract in rats.Ojewole JA, dewole SO,
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Olayiwola G.Cardiovasc J S Afr. 2006 Sep-Oct; 17(5):227-32.

10. 1) DESCRIPTION of Jamun….
•
An evergreen tropical tree 50 to 100 ft. tall, with oblong opposite leaves that
are smooth, glossy; they have a turpentine smell. The bark is scaly gray and
the trunk forks into multiple trunks about 3 - 5' from the ground.
•
Jamun has fragrant white flowers in branched clusters at stem tips and
purplish-black oval edible berries. The juicy fruit-pulp contains resin, gallic
acid and tannin; it tastes usually from acid to fairly sweet. The somewhat
astringent, jamun fruit can be utilized for juice.
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11. 2) REFERENCES ….
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The effect of Syzygium cumini (L.) seeds on post-prandial blood glucose levels in non- diabetic
rats and rats with streptozotocin-induced diabetes mellitus Claudio Coimbra Teixeiraa, Luciano
Pilla Pinto, Journal of Ethnopharmacology, Volume 56, (3), 1997, Pages 209-213
Hypoglycemia induced by Syzygium cumini Linn. Seeds in diabetes mellitus.Y Srivastava, H
Bhatt, OP Gupta, PS Gupta Asian Medical Journal 26:77, 489-492, 1983.
Eugenia jambolana: a plant drug with potential antidiabetic property (a review) Kohli, K. R. and
R. H. SinghJournal of Scientific Research in Plant Medicine 6, 21—28, 1986
Clinical observations on the antidiabetic properties of Pterocarpus marsupium and Eugenia
jambolana. Bose SN, Sepaha GC. J Indian Med Assoc. 1956 Dec 1; 27(11):388-91
Effect of jamun seed extract on alloxan induced diabetes in rats
Giri, J., T.K. Sakthidevi
and N. Dushyanthy Journal of the Diabetes Association of India 25, 4, 115, 1985
Effects of ethanolic extract of Syzygium cumini (Linn) seed powder on pancreatic islets of
alloxan diabetic rats.Singh N, Gupta M.Indian J Exp Biol. 2007 Oct; 45(10):861-7.
Hypoglycaemic effect of defatted seeds and water soluble fibre from the seeds of Syzygium
cumini (Linn.) skeels in alloxan diabetic rats.
Pandey M, Khan A.Indian J Exp Biol. 2002
Oct; 40(10):1178-82
Identification of alpha amylase inhibitors from Syzygium cumini Linn seeds. Karthic K, Kirthiram
KS, Sadasivam S, Thayumanavan B.
Indian J Exp Biol. 2008 Sep; 46 (9):677-80.
Syzygium cumini (L.) SKEELS (Myrtaceae) against diabetes--125 years of
research.Helmstädter A. Pharmazie. 2008 Feb; 63(2):91-101. Review.
Syzigium cumini seed extracts reduce tissue damage in diabetic rat brain. Stanely Mainzen
Prince P, Kamalakkannan N, Menon VP.J Ethnopharmacol. 2003 Feb; 84(2-3):205-9.
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12.  Growing condition of Karela – Jamun at Herbal Hills
International Quality standards adhered to give the best quality of Karela & Jamun.
Location: In the POLLUTION FREE Sahyadri Mountain range in Lonavala, Maharashtra,
India.
Water :
Filtered water used for cultivation is sourced from Indrayani River.
Soil :
Fertility of the Soil is maintained though the usage Organic Inputs, Vermicompost,
Biofertilisers, produced inhouse
Production
Ancient knowledge with modern cultivation is practiced in soil conditioning, seed treatment,
sowing & harvesting to get best results.
Method of growing: Outdoor
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13.  Manufacturing Process of Diabohills Juice at Herbal Hills
STEP : I
Processing Raw Herbs :
All the Raw Materials (RM) Karela, Amla Fruit, Harde, Baheda, Neem, giloy, Methi,
Ambehaldi, Sunthee, Shatavari, Ashwagandha, Kadu chirayata, Bel Leaves and Gudmar
are washed, cut and crushed into small pieces
STEP : II
• The mixture is boiled at 110oC
• The boiled material is then cooled at room temperature
STEP : III
• The pulp of Jamun (seeds of Jamun are not used) is prepared and mixed with all above
ingredients and crushed and water is added
• After the addition of preservative, the homogenized mixture is mixed thoroughly and In
process sample is taken and sent for testing.
• The sample passing specifications are taken for packing.
STEP : IV
•
The bottles are labeled & packed as per guidance
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14.  Finished Product Specification of Herbal Hills Diabohills
(Karela-Jamun) Juice
Sr. No.
Tests
Specification
1.
Description
Fibrous Dark Brown liquid
2.
Uniformity of weight
500 ml + 7.5 %
4.
pH ( !% Suspension)
Heavy Metals :
5.
Arsenic (As)
NMT 10 ppm
6.
Lead (Pb)
NMT 10 ppm
7.
Mercury (Hg)
NMT 1 ppm
8.
Cadmium (Cd)
NMT 0.3 ppm
Microbiological Analysis
9.
Total Microbial Count:
NMT 1000 Cfu / ml
10.
Yeast / Mould:
NMT 100 Cfu / ml
11.
Coliforms
Absent
12.
Escherichia coli:
Absent
13
Salmonella
Absent
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15. Benefits of Diabohills (Karela-Jamun) Juice
 Maintains Healthy Blood Sugar level
 Rich in Phyto Nutrients like Dietary fiber,
Minerals, Vitamins
 Acts as an anti-oxidant
 Helps prevent excess sugar absorption
 Helps in detoxifying the blood
 Helps to protect tissues
 Improves Muscles, tissues
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