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Andrew Illhardt
        8–9B
 Hepatoblastoma only affects
  children of 3 years or younger.
 Hepatoblastoma is a tumor that
  originates in the liver or
  gallbladder and has a potential to
  spread to any other organs causing
  multiple kinds of cancer.
 This disorder always starts out as a
  golf ball sized tumor on the right
  lobe of the liver.
 At around 18 months is when it
  starts.
 There are about 100 cases
  reported of this disorder each year.
 Many genetic disorders can lead to
  having Hepatoblastoma instead of
  the original disorder.
 The main two genetic disorders
  that lead to this disease Beckwith-
  Wiedemann syndrome and familial
  adenomatous polyposis
 This can be passed to the child
  through unknown recessive genes.
 Many disorders can cause
  Hepatoblastoma but they don’t
  always cause this disease.
This picture shows
                                 how big the abdomen
                                 can get.
    The most common
    symptoms include:
 A large abdominal mass, or
  swollen abdomen
 Weight loss
 Decreased appetite
 Abdominal pain.
 Vomiting.
 Jaundice – yellowing of eyes
  or skin.
 Fever
 Itching Skin
 Anemia – pale skin and lips
  from decreased number of red
  blood cells.
 Back pain from compression
  of the tumor.
 The only “prevention” is to see if
  you have the recessive genes
  either the disease itself or the
  other diseases that causes it.
 If you find out that you have the
  mutated genes then the best thing
  to do is to not have children. The
  chances of this, though, is small.
The tumor
                                                                    has
 Treatment depends on what stage                                   completely
  the tumor is at (stage 1, stage                                   consumed the
                                                                    right half of
  2, stage 3, or stage 4)                                           the liver in
 Stage 1: Easily and completely                                    this picture.
  removed tumor.                                                    This is usually
                                                                    what stage
 Stage 2: Removed with a little bit                                three looks
  of the tumor left, which is inactive                              like.
  because of a small amount of
  chemotherapy.
 Stage 3: Can’t be removed by
  surgery alone, must have
  chemotherapy (which causes hair
  loss) to decrease the size of the
  tumor, then the tumor gets
  removed, and the patient has to
  get medicine to completely kill the
  cancer (some studies show that
  chemotherapy causes hearing loss
  though it’s not completely proven.)
 Stage 4: No treatment, 100% fatal
                                         This is around a Stage 4
 http://www.lpch.org/DiseaseHealt
  hInfo/HealthLibrary/oncology/hep
  ato.html
 Prior Knowledge
 Information from doctors
 Parent’s knowledge

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Hepatoblastoma

  • 2.  Hepatoblastoma only affects children of 3 years or younger.  Hepatoblastoma is a tumor that originates in the liver or gallbladder and has a potential to spread to any other organs causing multiple kinds of cancer.  This disorder always starts out as a golf ball sized tumor on the right lobe of the liver.  At around 18 months is when it starts.  There are about 100 cases reported of this disorder each year.
  • 3.  Many genetic disorders can lead to having Hepatoblastoma instead of the original disorder.  The main two genetic disorders that lead to this disease Beckwith- Wiedemann syndrome and familial adenomatous polyposis  This can be passed to the child through unknown recessive genes.  Many disorders can cause Hepatoblastoma but they don’t always cause this disease.
  • 4. This picture shows how big the abdomen can get. The most common symptoms include:  A large abdominal mass, or swollen abdomen  Weight loss  Decreased appetite  Abdominal pain.  Vomiting.  Jaundice – yellowing of eyes or skin.  Fever  Itching Skin  Anemia – pale skin and lips from decreased number of red blood cells.  Back pain from compression of the tumor.
  • 5.  The only “prevention” is to see if you have the recessive genes either the disease itself or the other diseases that causes it.  If you find out that you have the mutated genes then the best thing to do is to not have children. The chances of this, though, is small.
  • 6. The tumor has  Treatment depends on what stage completely the tumor is at (stage 1, stage consumed the right half of 2, stage 3, or stage 4) the liver in  Stage 1: Easily and completely this picture. removed tumor. This is usually what stage  Stage 2: Removed with a little bit three looks of the tumor left, which is inactive like. because of a small amount of chemotherapy.  Stage 3: Can’t be removed by surgery alone, must have chemotherapy (which causes hair loss) to decrease the size of the tumor, then the tumor gets removed, and the patient has to get medicine to completely kill the cancer (some studies show that chemotherapy causes hearing loss though it’s not completely proven.)  Stage 4: No treatment, 100% fatal This is around a Stage 4
  • 7.  http://www.lpch.org/DiseaseHealt hInfo/HealthLibrary/oncology/hep ato.html  Prior Knowledge  Information from doctors  Parent’s knowledge