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CARDIO
VASCULAR
SYSTEM


dr. Indriati Dwi Rahayu
• SEL…….              EX : endothel, pricyte, dll


• JARINGAN……        !!! 4 JARINGAN DASAR !!!


• STRUKTUR/lapisan….. Ex : LEI,              LEE, dll

• ORGAN……      Jantung – sistem arteri – kapiler – vena
 Sel ???
   Shape
   Size
 Struktur  warna, isi, dsb
 Something around
 Something special
    the most remarkable feature.
 Staining
MICROSCOPIC VIEW
OF ANATOMIC STRUCTURES
  !!! 4 JARINGAN DASAR !!!

           Epithel

           Jaringan Ikat

           Syaraf

           Otot
komponen :
       jantung
       pembuluh darah :
        –kapiler
        –arteri (arteriol – kecil – sedang - besar)
        –Vena (venule-vena kecil-sedang- besar)

! Selalu terdapat ENDOTHEL di lapisan dalam (yang
  berbatasan dengan lumen)  Tunica Intima
! Tunica MEDIA berupa otot polos
! Tunica Adventitia berupa j.i. longgar
other features
                 Tunica intima            Tunica media                     tunica adventitia
Vessel name
                 Thick Endothelium.                                                                    An internal elastic lamina,
Elastic artery                            elastic fibers and a             connective tissue; vasa
                                                                                                       although present, may not be
or               thick                    series of concentrically         vasorum,                    easily discerned, since it is
                                          arranged. Between therelatively underdeveloped               similar to the elastic laminae of
Conducting       subendothelial                                                                        the next layer (that may hard to
artery           connective tissue        elastic laminae are (thin relative to vessel                 distinguish, too)
                                          smooth muscle cells, diameter)
                 porous LEI
                                          reticular fibers,
                 Endothelium.             may contain up to 40 layers of   connective tissue; vasa The internal elastic
Muscular
artery           The intima have a        smooth muscle                    vasorum                 lamina is prominent
or               subendothelial layer     cells. These cells are                                       between intima and
                                          intermingled with various                                    media. An external
distributing
                                          numbers of elastic                                           elastic lamina is
artery                                    lamellae (depending on
                                                                                                       present only in the larger
                                          the size of the vessel) as
                                                                                                       muscular arteries
                                          well as reticular fibers
                                                                                                       (medium artery)
                 Endothelium.                                              connective tissue; tunica
Arteriole                                composed of one to                adventitia is very thin.
                 subendothelial layer is
                                         five circularly arranged
                 very thin
                                          layers of smooth
                                          muscle cells; it shows
                                          no external elastic lamina
Capillary        Endothelium and
                 pericytes
other features
              Tunica intima            Tunica media              tunica adventitia
Vessel name
venule        Endothelium, lacks       a few smooth muscle       very thin connective       Together with
              valves                   cells (very thin)         tissue;                    arteriole

Medium (and   Endothelium (fewer       small bundles of          connective tissue; vasa Together with
small) vein   valve than in large      smooth muscle cells       vasorum. The             muscular artery
              vein). no LEI.           intermixed with           collagenous adventitial
                                       fewreticular fibers and   layer is well developed.
                                       a delicate network of
                                       elastic fibers
Large vein    Endothelium, well        few layers of smooth      The adventitial layer is
              developed                muscle cells and          the thickest and best-
              subendothelial.          abundant connective       developed tunic in
              extension of intima      tissue (reticular and     veins; it frequently
              protrude into lumen as   collagen). Elastin is     contains longitudinal
              valve                    sparse                    bundles of smooth
                                                                 muscle
ARTERIOLE
ARTERI KECIL
ARTERI SEDANG
ARTERI BESAR
VENULE
• Ø 0,2 – 1 μm
• T.Intima : - endothel tipikal
  T. Media : - otot polos [+]
              - tipis
- T. Adventitia : sangat tipis
VENA (KECIL)
Vasa vasorum   - Merupakan pembuluh
                 darah kecil untuk nutrisi
                 arteri/vena dg ø > 1 mm
               - berada di Tunica
                 adventitia
Summary
• Kapiler : epithel selapis pipih
• arteri
   – Arteriol : << 5 lapisan epithel
   – A.kecil : LEI [+]
   – A.sedang : LEI berkelok, LEE [+]
   – A.besar : Serabut elastik
• Vena : seperti pasangannya, tapi tipis, kolaps
• Jantung : discus intercalatus,,
CEKIDOT……
-O :……
- Lapisan :…..
-Sel :…
-Organ….
-Bangunan di sebelah kiri :….
-Lapisan :…….
-Jaringan : …..
-Struktur
Do your best…
and God will do the rest…..

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Praktikum CVS FKUB

  • 1.
  • 3.
  • 4.
  • 5. • SEL……. EX : endothel, pricyte, dll • JARINGAN…… !!! 4 JARINGAN DASAR !!! • STRUKTUR/lapisan….. Ex : LEI, LEE, dll • ORGAN…… Jantung – sistem arteri – kapiler – vena
  • 6.  Sel ???  Shape  Size  Struktur  warna, isi, dsb  Something around  Something special  the most remarkable feature.  Staining
  • 7. MICROSCOPIC VIEW OF ANATOMIC STRUCTURES !!! 4 JARINGAN DASAR !!!  Epithel  Jaringan Ikat  Syaraf  Otot
  • 8. komponen : jantung pembuluh darah : –kapiler –arteri (arteriol – kecil – sedang - besar) –Vena (venule-vena kecil-sedang- besar) ! Selalu terdapat ENDOTHEL di lapisan dalam (yang berbatasan dengan lumen)  Tunica Intima ! Tunica MEDIA berupa otot polos ! Tunica Adventitia berupa j.i. longgar
  • 9. other features Tunica intima Tunica media tunica adventitia Vessel name Thick Endothelium. An internal elastic lamina, Elastic artery elastic fibers and a connective tissue; vasa although present, may not be or thick series of concentrically vasorum, easily discerned, since it is arranged. Between therelatively underdeveloped similar to the elastic laminae of Conducting subendothelial the next layer (that may hard to artery connective tissue elastic laminae are (thin relative to vessel distinguish, too) smooth muscle cells, diameter) porous LEI reticular fibers, Endothelium. may contain up to 40 layers of connective tissue; vasa The internal elastic Muscular artery The intima have a smooth muscle vasorum lamina is prominent or subendothelial layer cells. These cells are between intima and intermingled with various media. An external distributing numbers of elastic elastic lamina is artery lamellae (depending on present only in the larger the size of the vessel) as muscular arteries well as reticular fibers (medium artery) Endothelium. connective tissue; tunica Arteriole composed of one to adventitia is very thin. subendothelial layer is five circularly arranged very thin layers of smooth muscle cells; it shows no external elastic lamina Capillary Endothelium and pericytes
  • 10. other features Tunica intima Tunica media tunica adventitia Vessel name venule Endothelium, lacks a few smooth muscle very thin connective Together with valves cells (very thin) tissue; arteriole Medium (and Endothelium (fewer small bundles of connective tissue; vasa Together with small) vein valve than in large smooth muscle cells vasorum. The muscular artery vein). no LEI. intermixed with collagenous adventitial fewreticular fibers and layer is well developed. a delicate network of elastic fibers Large vein Endothelium, well few layers of smooth The adventitial layer is developed muscle cells and the thickest and best- subendothelial. abundant connective developed tunic in extension of intima tissue (reticular and veins; it frequently protrude into lumen as collagen). Elastin is contains longitudinal valve sparse bundles of smooth muscle
  • 13.
  • 15.
  • 17. VENULE • Ø 0,2 – 1 μm • T.Intima : - endothel tipikal T. Media : - otot polos [+] - tipis - T. Adventitia : sangat tipis
  • 19. Vasa vasorum - Merupakan pembuluh darah kecil untuk nutrisi arteri/vena dg ø > 1 mm - berada di Tunica adventitia
  • 20.
  • 21.
  • 22. Summary • Kapiler : epithel selapis pipih • arteri – Arteriol : << 5 lapisan epithel – A.kecil : LEI [+] – A.sedang : LEI berkelok, LEE [+] – A.besar : Serabut elastik • Vena : seperti pasangannya, tapi tipis, kolaps • Jantung : discus intercalatus,,
  • 25. -Sel :… -Organ…. -Bangunan di sebelah kiri :….
  • 26.
  • 27. -Lapisan :……. -Jaringan : ….. -Struktur
  • 28. Do your best… and God will do the rest…..