Poster 54 hematologie

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PREVALENCE OF HAEMOGLOBIN VARIANTS IN GREEK PATIENTS

Salud y medicina Tecnología

2011 Hematologie Hematology Poster 54 PREVALENCE OF HAEMOGLOBIN VARIANTS IN GREEK PATIENTS Marilena Stamouli , Anastasios Skliris, Grigorios Totos, Dimitrios Kokoulas and Efrosini Karagianni Department of Microbiology and Immunology, Naval and Veterans Hospital, Athens, Greece

Hematologie Hematology Poster 54 ,[object Object],[object Object],[object Object],[object Object],Facts and Objectives 2011

2011 Hematologie Hematology Poster 54 ,[object Object],[object Object],[object Object],[object Object],[object Object],Materials and Methods (I)

2011 Hematologie Hematology Poster 54 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Materials and Methods (II)

[object Object],[object Object],[object Object],2011 Hematologie Hematology Poster 54 Results (I)

[object Object],[object Object],[object Object],[object Object],2011 Hematologie Hematology Poster 54 Results (II)

[object Object],[object Object],[object Object],[object Object],[object Object],2011 Hematologie Hematology Poster 54 Discussion

[object Object],[object Object],[object Object],2011 Hematologie Hematology Poster 54 Concluding Remarks

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Introduction: Microcytic hypochromic anemia is a distinct morphologic subtype of anemia with well-defined etiology and treatment. Anemia is a major public health problem worldwide despite the remarkable improvement in living conditions. This study aimed to determine the prevalence of hypochromic microcytic anemia and to identify the different etiologies in patients hospitalized in the ward during the study period. Methods: This was a retrospective study two years, including patients hospitalized in the Hematology-oncology department. Results: Out of a total of 114 patients hospitalized for anemia, we collected 65 cases of hypochromic microcytic anemia (57.02%). The mean age was of 37.43 years. The sex ratio was 1.95. Pallor was the physical sign predominantly 100% of the cases. The most predominant associated pathology was malaria (95.38%). Twenty one patients (32.3%) had a hemoglobin level between 4 and 5 g/dl. The most incriminated causes in the occurrence of hypochromic microcytic anemia were anemia due to iron deficiency 50.77% and anemia due to inflammatory syndrome 43.08%. Conclusion: Our study shows that hypochromic microcytic anemia has various etiologies and its prevalence is not negligible in the Hematology-oncology department of Donka Hospital.

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Hemoglobinopathies are congenital disorders resulting from hemoglobin abnormalities. Major forms are often severe, their management is difficult and associated with a great psychosocial impact on patients and their families. These hemoglobinopathies may be due to alterations in certain globin chains that include: Absence of production Diminished production Abnormal structure. The clinically significant hemoglobinopathies include α- and β-thalassemia, sickle cell disease, HbE disease, and HbC disease.

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