Tablet manufacturing unit layout for pharmaceutical plant

1. FACTORY LAYOUT
Presented By
Mr. Mitkari Jayshankar V.
M.Pharm (Sem II)
Under the guidance
Of
Mr. Bidkar J.S.
(Asst. prof.)
M.Pharm
Sharadchandra Pawar college of Pharmacy, Otur, Pune.

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3. GOALS PRODUCTION PLANT LAYOUT
 Plan for the preferred situation in the future
 Layout must support objectives of the facility
 No accurate data  layout must be flexible

4. Three types of layout-
1. Circular Flow
2. Parallel Flow
3. Crossover Traffic
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TYPES OF TABLET
MANUFACTURING LAYOUT

5. CIRCULAR FLOW:
 It consists of receiving , approved raw materials,
components storage, and dispensing on one side, with
manufacturing, quarantine, bulk stock, and packaging
across a central corridor.
 Advantage: Since the flow is circular so it eliminates
much of crossover traffic.

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8. CENTRE WAREHOUSE:
 In this type the centre, warehouse area for raw materials, packaging
components, and bulk stocks, with the manufacturing and
packaging operations located at the outer perimeter.
 Advantage: Space conservation by virtue of having the supply
areas close to the areas being supplied.
 Disadvantage: Chances of contamination or mix up b/c of
crossover traffic pattern of material.

10. MIXING, GRANULATION & DRYING AREA
 Powder mixer
 Mass mixer / Planetary mixer/
Rapid mixer granulator.
 Granulators
 (High shear granulator, chilsonator)
 Tray dryer/FBD
 Weighing Machines
TABLET GRANULATION

11. Machines
Digital
Weighing
balance
Mixer Granulator Miller

12. Machines (cont.)
Blender Tablet press BlisteringCoating
Packaging

13. Granulation technology on large scale by varioustechniques

14. TABLET GRANULATING AREA

15. 1-Tablet Compression Machine:
Single punch/Multi-punch/
Rotatory punch
& Die storage cabinet
2-Tablet Inspection Unit & belt
3-Dissolution Testing Apparatus
4-IPQC- instruments
TABLET COMPRESSION

16. BOOTH-1 BOOTH-3
PALLET FOR
ROTARY &
SINGLE PUNCH PRESSES FOR LARGER PRESSES
BOOTH-2
FOR ROTARY &
SINGLE PRESSES
AREA FOR SINK & STORAGE FOR
DIES & PUNCHES & MACHINE
PALLET TOOLING
TABLET COMPRESSING AREA
PAPA
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PPPPP
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17. REFERANCE
 Lachman L. The Theory and practice of industrial
pharmacy. 3rd Edition. Varghese publication house.
 www.authorstream.com
 www.scribd.com
 Wikipedia.com

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