This document provides a summary of the background and qualifications of Dr. Jérôme LARCHÉ. He is an internist and medical intensivist based in France with over 25 years of experience. His experience includes serving as head of the intensive care unit at Narbonne General Hospital from 2011-2014 and founding a non-profit organization focused on bacteriophage research in 2009. He has published numerous peer-reviewed articles and holds masters degrees focusing on tropical diseases and cardiology. His areas of expertise include ICU medical care and management as well as extrarenal support devices.

1. Dr Jérôme LARCHÉ (MD, Msc, MPS)
- Internist /Medical Intensivist -
8, rue Jean Laborde
11590 Cuxac d’Aude - France
Tel : +33 (0)6-11-31-20-15
E-mail: jlarchemdm@gmail.com
Birthdate: 14th February 1969 / 2 children
Driving license B (car)
Fluent English (spoke, written, read) / Scholar German / Beginning Arabic / Basics of Bengali
Judo (black belt) / Trail / Squash
Praticien hospitalier - N° Finess: 110780137
Main skills and competencies: Medical care in various settings / Team management / Transmission of
knowledge / Expertise on ICU medical devices (and notable extrarenal support)
Medical Profile
ACADEMIC and HOSPITAL ACHIEVEMENTS
2011-2014. Head of Intensive Care Unit in Narbonne General hospital (nearby Montpellier)
Since July 2009. President of PHAGESPOIRS (non-profit organization aiming at supporting patients, promoting research
and therapeutic use of bacteriophages, virus that kill multi-drug resistant bacteria)
2005-2010. Senior Physician in ICU
- Narbonne General hospital (since 2008)
- Montpellier universitary hospital / Clinique du Parc (2006-2008)
Nancy universitary hospital (2005-2006)
2008-2009. Private medical activity
- SOS International (Mongolia, Nigeria)
- Medevasan (sanitary rapatriation)
2005. Nomination to National Exam for Senior Physician
2004. Master 2 degree in Biological Science « Maladies Transmissibles et Pathologies Tropicales » Mention Bien - (Pr
D. Raoult – Marseille)
« Implications des anomalies mitochondriales dans les processus d’apoptose et de dysfonction cardiaque septique dans un
modèle murin » (Pr R. Nevière – Lille)
2003. Specialized Diploma in Medical Intensive Care
2002-2004. Post-graduate physician - ICU - Pr Gérard- Nancy universitary hospital
2002. Medical Doctor degree : « Transfert en réanimation des patients neutropéniques fébriles : épidémiologie, facteurs
prédictifs et modélisation d’un score pronostique »
2002. Specialized Diploma of Internal Medicine : « Patients onco-hématologiques hospitalisés en réanimation pour sepsis
sévère et choc septique »
1996. Civil service – Medical doctor at French Embassy in Bangladesh
1995-2001. Internship (Internal Medicine) –Nancy universitary hospital
Main publications in peer-reviewed journals (PUBMED):

2. • Larché J, Pouillot F, Essoh C, Libisch B, Straut M, Lee JC, Soler C, Lamarca R, Gleize E, Gabard J,
Vergnaud G, Pourcel C. Rapid identification of international multidrug resistant Pseudomonas
aeruginosa clones by multiple locus VNTR analysis (MLVA) and investigation of their susceptibility to
lytic bacteriophages. Antimicrob Agents Chemother, 2012 Sep 17.
• Carlet J, Rambaud C, Pulcini C; l'Alliance contre développement des bactéries multirésistantes
(ACdeBMR). Alliance against MDRO: safeguarding antibiotics. Ann Fr Anesth Reanim. 2012
Sep;31(9):704-8
• Bataille B, Bertuit M, Mora M, Mazerolles M, Cocquet P, Masson B, Moussot PE, Ginot J, Silva S,
Larché J. Comparison of esCCO and transthoracic echocardiography for non-invasive measurement of
cardiac output intensive care. Br J Anaesth, 2012 Aug 19.
• Muller L, Jaber S, Molinari N, Favier L, Larché J, Motte G, Lazarovici S, Jacques L, Alonso S, Leone
M, Constantin JM, Allaouchiche B, Suehs C, Lefrant JY; AzuRéa Group. Fluid management and risk
factors for renal dysfunction in patients with severe sepsis and/or septic shock. Crit Care, 2012 Feb
29;16(1):R34
• Brun-Buisson C, Richard JC, Mercat A, Thiébaut AC, Brochard L; REVA-SRLF A/H1N1v 2009
Registry Group. Early corticosteroids in severe influenza A/H1N1 pneumonia and acute respiratory
distress syndrome. Am J Respir Crit Care Med. Am J Respir Crit Care Med, 2011 May 1;183(9):1200-6
• J. Larché, B. Masson, P. Cocquet, M. Piqué, J. Ginot, JC. Gouiry. Amélioration par une EPP des
modalités de prise de décision de LATA en réanimation. Clinical Impact of quality improvements.
Quality and Safety in Health Care, April 2010; vol 19 (1), A 73
• Caillot D, Thiébaut A, Herbrecht R, de Botton S, Pigneux A, Bernard F, Larché J, Monchecourt F,
Alfandari S, Mahi L. Liposomal amphotericin B in combination with caspofungin for invasive
aspergillosis in patients with hematologic malignancies: a randomized pilot study (Combistrat trial).
Cancer. 2007 Dec 15;110(12):2740-6.
• J. Larché, S. Lancel, S.M. Hassoun, et coll. Inhibition of mitochondrial permeability transition
prevents sepsis-induced myocardial dysfunction and mortality. J Am Coll Cardiol 2006; 48(2): 377-385
• M. Machouart, J. Larché, K. Burton, et coll. Genetic identification of the main opportunistic Mucorales
by PCR-restriction fragment lenght polymorphism. J Clin Microbiol 2006; 44(3): 805-810
• J. Larché, M. Machouart, K. Burton, et coll. Cutaneous mucormycosis in a patient with aggressive B
lymphoma: identification of Rhizopus sp. by an innovative PCR-RFLP method. Clinical Infectious
Diseases 2005; 41(9): 1362-1365
• J. Larché, E. Azoulay, C. Alberti, et coll. Prompt management of critically ill cancer patients with
septic shock improves outcome. Intensive Care Medicine 2003 ; 29 (10) : 1688-95
• S. Ducki, C. Hulin, I. Raclot, J. Larché. Crusted scabies in a patient with chronic GVH: difficulty of
diagnosis and consequences. Med Mal Infect 2004; 34(10): 485-487
• Gérard, J. Larché. Place des glycopeptides en réanimation. Med Mal Infect 2004; 34(suppl 1): S97-S98