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Introducing ARRAY OnQ
iPad technology and on-site service that bring
increased engagement, more participation
and a whole new “Wow Factor” to your events.
ARRAY OnQ runs on its
own private network
and server, so you won’t
need to worry about
unreliable and expensive
hotel or venue Wi-Fi
service. With ARRAY OnQ
there are no issues with
connectivity and all data
and content are secure.
The data collected using
ARRAY OnQ goes into
our highly powerful
and user-friendly data
analysis software. You
can filter data sets, look
at all your programming
or focus on one meeting
and evaluate impact.
The system also creates
a summary by slide of
notes taken, questions
asked, and slide rating.
For over 10 years, EM has
provided on-site technical
service at over 5,000
events ranging in size from
10 people to 1,000.
We get it.
Welcome to ARRAY OnQ.
Companies are being asked to improve interaction at their live events and collect
quality data points to measure impact. Educational Measures developed ARRAY
for this reason and we stand apart from our competitors because:
About EM
We develop and deploy event
technolgies and top-end service
for a wide variety of industries.
ARRAY OnQ Features
4Stream and navigate live slides
4Built in polling
4Send questions to the moderator
4Take notes by slides
4Complete surveys
4Access electronic course manuals
4Provide summary reports to clients by slide
or by participant
+Improve interactivity and data collection!
Our user interface is
designed based on
participant feedback
so it is intuitive
and easy-to-use.
Slides display in real-time
as presented, but can be
navigated forward and
backward through the
presentation.
ARRAY OnQ Features
4Stream and navigate live slides
4Built in polling
4Send questions to the moderator
4Take notes by slides
4Complete surveys
4Access electronic course manuals
4Provide summary reports to clients by slide
or by participant
+Improve interactivity and data collection!
Can you navigate forward and
backward through the live slides
being shown?
Real-time Questions:
Attendees can
ask questions while
the meeting is in
progress. Presenters
will see it on their
display.
ARRAY OnQ Features
4Stream and navigate live slides
4Built in polling
4Send questions to the moderator
4Take notes by slides
4Complete surveys
4Access electronic course manuals
4Provide summary reports to clients by slide
or by participant
+Improve interactivity and data collection!
Contact EM about our next
meeting!
ValuedClient@meeting.com
ARRAY OnQ
enables users to take
notes – either by
typing, or by writing
or drawing with
a stylus
Polling:
Ask questions at
any time during a
presentation. Attendees
respond by simply
tapping their choice.
“The Add-on Impact of Mobile Applications in Learning Strategies: A 
Review Study” states that infusing iPads in the live learning environ-
ment is  fundamentally changing the ability of faculty to engage  par-
ticipants, increase  interactivity, and improve efficiency in learning. A
recent study found that mobile  technologies such as iPads have:
= Increased participant  engagement in learning
= Enabled collaborative  learning
= Increased productivity and  efficiency during learning
= All of the above
Polling Question #1
“The Add-on Impact of Mobile Applications in Learning Strategies: A  Review Study” states that
infusing iPads in the live learning environment is  fundamentally changing the ability of faculty
to engage  participants, increase  interactivity, and improve efficiency in learning. A recent study
found that mobile  technologies such as iPads have:
1. Increased participant  engagement in learning
2. Enabled collaborative  learning
3. Increased productivity and  efficiency during learning
4. All of the above
Polling results
can be displayed
immediately.
Polling Question #1: Result
Conduct surveys
and evaluations
at any time. Data
collected is
compatible with
our analytics
application.
Survey
Presenter Bios
Christina Yieh
Science Director
Tellent Labs, Inc.
Christina Yieh has been Science Director for Tellent Labs since 2011.
Tellent is a world leader in microbiobial and genetic research with
over 20 years of funded experience, working closely with 11 major universities and research
institutions.
Christina Yieh joined the company in 2008 and worked in a variety of positions in the US and
in the UK. In 2009, she went to Paris, France as Science Development European Lead, manag-
ing global research programs. She returned to New York in May 2011 as Science Director and
since managed the development and launch of the division’s research paths.
Prior to joining Tellent, Yieh worked at PharMeta as a Science and lab lead. She received a
Masters of Science from Columbia University, New York and a Bachelors degree in Biology
from John Cabot International College in Rome, Italy.
Add all
of your pertintent
meeting information
with our flexible
tab system.
Participants can
rate each slide and
the results can be
viewed in the final
engagement report.
Tabs can be added
and customized to
suit your needs.
Engagement Report:
By-slide summary reports
help you track particpation
and effectiveness.
Includes all notes
taken and questions
asked by slide.
Additional Reports:
ARRAY OnQ offers
you a wide range of
additional in-depth reports.
genda Morning 1130	
  Vij sburstei@yahoo.com 2014-­‐06-­‐21	
  10:53:53 Will	
  a	
  pt	
  who	
  has	
  failed	
  post	
  transplant	
  maintenance	
  revlimid	
  qualify	
  for	
  the	
  anti	
  cd38	
  trial?
genda Morning 1130	
  Vij syed.huq@mercy.net 2014-­‐06-­‐21	
  11:09:31 For	
  pts	
  with	
  17p	
  del	
  is	
  Ibrutinib	
  a	
  reasonable	
  option	
  in	
  the	
  first	
  line	
  setting
genda Morning 1130	
  Vij axs2115@bjc.org 2014-­‐06-­‐21	
  11:09:50 Do	
  you	
  consider	
  gazyva	
  as	
  a	
  first	
  line	
  standard	
  of	
  care	
  now?
genda Morning 1130	
  Vij ahusain01@hotmail.com 2014-­‐06-­‐21	
  11:11:20 Comment	
  about	
  ideally	
  sib	
  in	
  cll
genda Morning 1130	
  Vij sburstei@yahoo.com 2014-­‐06-­‐21	
  11:11:57 Ibrutinib	
  in	
  myeloma?
genda Morning 1130	
  Vij bethany.sleckman@mercy.net2014-­‐06-­‐21	
  11:12:36 How	
  do	
  you	
  assess	
  response	
  to	
  ibrutinib	
  in	
  CLL,	
  especially	
  in	
  patients	
  without	
  lymphadenopathy?	
  
genda Morning 1130	
  Vij jcarden@hsillc.com 2014-­‐06-­‐21	
  11:13:12 In	
  cll	
  with	
  17p	
  deletion	
  will	
  you	
  combine	
  ibrutinib	
  with	
  rituxan
genda Morning 1130	
  Vij mary@marymuscato.com 2014-­‐06-­‐21	
  11:13:42 Heard	
  about	
  PTH	
  PR.	
  Not	
  regular	
  PTH	
  causing	
  huge	
  hypercalcemia	
  in	
  CLL?	
  	
  I	
  have	
  a	
  pt	
  w/	
  stag.	
  O	
  CLL.	
  	
  Neg	
  for	
  cd38.	
  	
  
genda Morning 1130	
  Vij jcarden@hsillc.com 2014-­‐06-­‐21	
  11:20:09 Does	
  the	
  rituxan	
  clean	
  the	
  circulating	
  lymphocytes
genda Morning TITLE	
  SLIDE karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21	
  08:28:47 How	
  to	
  follow	
  with	
  PETi	
  when	
  	
  CMS	
  has	
  limited	
  a	
  total	
  of	
  3	
  PET	
  per	
  diagnosis	
  per	
  life	
  time?
genda Morning TITLE	
  SLIDE axs2115@bjc.org 2014-­‐06-­‐21	
  09:55:25 Is	
  zytiga	
  just	
  a	
  less	
  toxic	
  ketoconazole	
  essentially?
genda Morning TITLE	
  SLIDE dr.liana.makarian@ozarksmedicalcenter.com2014-­‐06-­‐21	
  09:56:23 What	
  was	
  the	
  median	
  age	
  for	
  trial	
  combining	
  taxotere	
  and	
  ADT.
genda Morning 9:10	
  -­‐	
  Carson syed.huq@mercy.net 2014-­‐06-­‐21	
  08:46:04 How	
  do	
  oncologists	
  balance	
  responsibility	
  to	
  individual	
  patients	
  vs	
  responsible	
  stewardship	
  of	
  healthcare	
  costs	
  or	
  is	
  that	
  even	
  the	
  responsibility	
  of	
  the	
  indiv
genda Morning 9:10	
  -­‐	
  Carson jmuscato@gmail.com 2014-­‐06-­‐21	
  08:54:00 Comment	
  re	
  hospitalization	
  of	
  NSCLC	
  patients:	
  a	
  lot	
  get	
  admitted	
  for	
  exacerbation	
  of	
  COPD.	
  These	
  patients	
  may	
  have	
  had	
  worse	
  overall	
  PS	
  to	
  begin	
  with.	
  Al
genda Morning 9:10	
  -­‐	
  Carson karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21	
  08:56:57 Abst.	
  6519:	
  Is	
  it	
  possible	
  that	
  pts.	
  on	
  clinical	
  trials	
  are	
  watched	
  more	
  closely	
  than	
  real	
  world	
  pts.	
  so	
  most	
  neutropenic	
  fever	
  are	
  taken	
  care	
  of	
  	
  earlier?
genda Morning 9:10	
  -­‐	
  Carson arifbari2000@yahoo.com 2014-­‐06-­‐21	
  08:59:34 Could	
  you	
  comment	
  on	
  surveillance	
  imaging	
  on	
  non	
  small	
  cell	
  lung	
  cancer,	
  frequency	
  and	
  length	
  of	
  imaging,	
  and	
  CT	
  vs	
  PET??
genda Morning 9:10	
  -­‐	
  Carson karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21	
  09:00:33 Previous	
  Asb.	
  8502	
  showed	
  benefit	
  for	
  PET/CT	
  for	
  prediction	
  of	
  PRS	
  	
  OS.	
  Since	
  CMS	
  has	
  limited	
  a	
  total	
  PET	
  of	
  3	
  per	
  diagnosis	
  per	
  life	
  time,	
  any	
  recommend
genda Morning 9:10	
  -­‐	
  Carson jmuscato@gmail.com 2014-­‐06-­‐21	
  09:03:15 How	
  does	
  Watson	
  decide	
  if	
  those	
  12M	
  pages	
  are	
  really	
  valid	
  or	
  good	
  studies?	
  
genda Morning 9:10	
  -­‐	
  Carson medicusaf4@att.net 2014-­‐06-­‐21	
  09:04:44 Explosion	
  of	
  oncology	
  meds,	
  treatments	
  -­‐	
  I	
  need	
  Watson	
  IBM	
  Now,	
  how	
  do	
  I	
  sign	
  up??
genda Morning 9:10	
  -­‐	
  Carson karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21	
  09:09:28 ASb.	
  6513:	
  is	
  it	
  possible	
  the	
  30%	
  of	
  stage	
  III	
  colon	
  pts.	
  Who	
  did	
  not	
  receive	
  FOLFOX	
  x	
  12	
  due	
  to	
  	
  surgical	
  complications	
  /	
  bowel	
  obstruction,	
  those	
  pts.	
  Died	
  o
genda Morning 8:30	
  -­‐	
  Bartlett lgiannone@aol.com 2014-­‐06-­‐21	
  07:53:17 What	
  maintenance	
  rituxan	
  schedule	
  do	
  you	
  recommend
genda Morning 8:30	
  -­‐	
  Bartlett jmuscato@gmail.com 2014-­‐06-­‐21	
  08:20:25 Do	
  those	
  FL	
  patients	
  with	
  a	
  positive	
  PET	
  reflect	
  the	
  possibility	
  of	
  some	
  large	
  cell	
  components	
  vs.	
  just	
  response	
  to	
  therapy?	
  Re	
  8502
genda Morning 8:30	
  -­‐	
  Bartlett dr.liana.makarian@ozarksmedicalcenter.com2014-­‐06-­‐21	
  08:20:46 Does	
  it	
  mean	
  that	
  pet	
  negative	
  follicular	
  lymphoma	
  after	
  induction	
  does	
  not	
  need	
  maintenance	
  rituxan?	
  
genda Morning 8:30	
  -­‐	
  Bartlett syed.huq@mercy.net 2014-­‐06-­‐21	
  08:23:37 In	
  pts	
  with	
  negative	
  pet	
  post	
  tax,	
  can	
  you	
  skip	
  maintenance	
  rituxan	
  since	
  OS	
  better	
  than	
  PRIMA
genda Morning 9:50	
  -­‐	
  Picus jmaheshwari@yahoo.com 2014-­‐06-­‐21	
  09:21:30
Is	
  weekly	
  taxotere	
  is	
  equally	
  effective	
  and	
  better	
  tolerated?
genda Morning 9:50	
  -­‐	
  Picus jward2@dom.wustl.edu 2014-­‐06-­‐21	
  09:25:41 Will	
  the	
  early	
  data	
  on	
  the	
  use	
  of	
  taxotere	
  in	
  the	
  first	
  line	
  setting	
  in	
  high	
  volume	
  disease	
  change	
  your	
  clinical	
  practice?
genda Morning 9:50	
  -­‐	
  Picus medicusaf4@att.net 2014-­‐06-­‐21	
  09:48:26 Discordance	
  between	
  12-­‐core	
  prostate	
  biopsy	
  and	
  radical	
  prostatectomy	
  specimen.	
  	
  I	
  have	
  seen	
  many	
  radically	
  removed	
  prostates	
  with	
  a	
  very	
  tiny	
  focus	
  of
genda Afternoon 1540	
  Wartman karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21	
  15:27:29
I	
  have	
  a	
  recent	
  patient	
  presented	
  with	
  diagnosis	
  of	
  Sebaceous	
  carcinoma	
  of	
  the	
  (R)	
  facial/	
  mandibular	
  area	
  	
  sebaceous	
  adenoma	
  of	
  abdominal	
  wall	
  are
(1)	
  Please	
  explain	
  the	
  prevalence	
  of	
  pleomorphism	
  in	
  the	
  setting	
  of	
  Muir	
  Torre	
  syndrome;
(2)	
  What	
  is	
  the	
  clinical	
  significance	
  of	
  pleomorphism	
  for	
  my	
  patient	
  	
  his	
  family	
  members?
genda Afternoon 2:00	
  -­‐	
  Sorscher	
  NEW jmaheshwari@yahoo.com 2014-­‐06-­‐21	
  13:38:45 When	
  we	
  will	
  use	
  neuadjuvant	
  folfox	
  in	
  locally	
  advanced	
  rectal	
  cancer	
  before	
  chemo	
  radiation?
genda Afternoon 2:00	
  -­‐	
  Sorscher	
  NEW syed.huq@mercy.net 2014-­‐06-­‐21	
  13:42:49 Should	
  we	
  be	
  recommending	
  multigene	
  panels	
  which	
  many	
  companies	
  are	
  marketing	
  for	
  hereditary	
  cancers,	
  given	
  the	
  ls	
  pts	
  carrying	
  brca	
  mutations?
genda Afternoon 2:00	
  -­‐	
  Sorscher	
  NEW jward2@dom.wustl.edu 2014-­‐06-­‐21	
  13:46:41 You	
  make	
  a	
  case	
  for	
  resection	
  of	
  the	
  primary	
  tumor	
  in	
  CRC	
  in	
  the	
  modern	
  era.	
  	
  Shouldn't	
  we	
  do	
  a	
  randomized	
  clinical	
  trial?
genda Afternoon 2:00	
  -­‐	
  Sorscher	
  NEW gajera@hotmail.com 2014-­‐06-­‐21	
  13:47:33
When	
  to	
  have	
  surgery	
  for	
  primary	
  in	
  metastatic	
  colon	
  cancer	
  .?	
  Before	
  chemo	
  ?
genda Afternoon 2:00	
  -­‐	
  Sorscher	
  NEW jmaheshwari@yahoo.com 2014-­‐06-­‐21	
  13:49:05
Natural	
  history	
  of	
  stage	
  4	
  colon	
  cancer	
  
Surgery	
  7-­‐8	
  months
Fu	
  add	
  6	
  weeks
iFL	
  17
Folfox	
  avast	
  in	
  24-­‐30	
  months
How	
  can	
  surgery	
  patient	
  will	
  be	
  longer?
genda Afternoon 2:00	
  -­‐	
  Sorscher	
  NEW jward2@dom.wustl.edu 2014-­‐06-­‐21	
  13:55:20 EORTC	
  22921	
  concluded	
  that	
  adjuvant	
  chemotherapy	
  is	
  unnecessary	
  in	
  patients	
  with	
  rectal	
  cancer	
  who	
  received	
  per	
  operative	
  chemo	
  radiotherapy.	
  	
  Is	
  ther
genda Afternoon 2:00	
  -­‐	
  Sorscher	
  NEW ahusain01@hotmail.com 2014-­‐06-­‐21	
  13:56:17 What	
  is	
  maxim	
  permissible	
  time	
  for	
  starting	
  adjuvant
genda Afternoon 2:00	
  -­‐	
  Sorscher	
  NEW syed.huq@mercy.net 2014-­‐06-­‐21	
  13:59:47 Isnt	
  a	
  200	
  pt	
  study	
  underpowered	
  to	
  detect	
  a	
  difference	
  in	
  stage	
  2	
  colon	
  pts	
  for	
  folfox,	
  since	
  recurrence	
  rate	
  is	
  6%
genda Afternoon 2:00	
  -­‐	
  Sorscher	
  NEW sburstei@yahoo.com 2014-­‐06-­‐21	
  14:00:16 	
  Stage2msi	
  high	
  oxali	
  alone?
genda Afternoon 12:10	
  -­‐	
  Linette jward2@dom.wustl.edu 2014-­‐06-­‐21	
  11:59:14 It	
  has	
  been	
  thought	
  that	
  immune	
  therapy	
  like	
  ipilimumab	
  is	
  more	
  effective	
  when	
  disease	
  is	
  present	
  to	
  prime	
  the	
  immune	
  system,	
  does	
  the	
  adjuvant	
  data	
  as
genda Afternoon 12:10	
  -­‐	
  Linette axs2115@bjc.org 2014-­‐06-­‐21	
  11:59:16 Do	
  you	
  think	
  eortc	
  9008	
  should	
  have	
  used	
  High	
  dose	
  IFN	
  as	
  standard	
  arm	
  instead	
  of	
  placebo	
  against	
  ipilimumab?
genda Afternoon 12:10	
  -­‐	
  Linette jcarden@hsillc.com 2014-­‐06-­‐21	
  12:00:43 Does	
  Ipilimumab	
  should	
  replace	
  interferon	
  in	
  adjuvant	
  therapy	
  of	
  stage	
  III	
  melanoma	
  ?
genda Afternoon 12:10	
  -­‐	
  Linette lgiannone@aol.com 2014-­‐06-­‐21	
  12:03:28 What	
  is	
  the	
  role	
  of	
  IL-­‐2	
  in	
  metastatic	
  melanoma
genda Afternoon 12:10	
  -­‐	
  Linette jcarden@hsillc.com 2014-­‐06-­‐21	
  12:17:52 What	
  is	
  yours	
  first,	
  second,	
  etc.	
  line	
  therapy	
  for	
  metastatic	
  malignant	
  melanoma?	
  
genda Afternoon 12:10	
  -­‐	
  Linette axs2115@bjc.org 2014-­‐06-­‐21	
  12:22:10 Are	
  kras	
  and	
  Nras	
  mutations	
  mutually	
  exclusive?
genda Afternoon 12:10	
  -­‐	
  Linette syed.huq@mercy.net 2014-­‐06-­‐21	
  12:25:09 Still	
  a	
  role	
  for	
  chemo	
  with	
  carbo-­‐taxol+Bev	
  without	
  braf	
  mutation?
genda Afternoon 1:20	
  -­‐	
  Morgensztern	
  NEW rvij@dom.wustl.edu 2014-­‐06-­‐21	
  12:38:47 Is	
  Brazil	
  going	
  to	
  win	
  the	
  World	
  Cup?
genda Afternoon 1:20	
  -­‐	
  Morgensztern	
  NEW jmaheshwari@yahoo.com 2014-­‐06-­‐21	
  12:49:17 After	
  this	
  PCI	
  study	
  would	
  you	
  offer	
  PCI?
genda Afternoon 1:20	
  -­‐	
  Morgensztern	
  NEW karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21	
  12:51:26 PCI	
  dose	
  of	
  25	
  Gy	
  in	
  10	
  fx.	
  is	
  too	
  low	
  .	
  The	
  radiobiological	
  	
  equivalent	
  of	
  only	
  30Gy	
  with	
  standard	
  fractionation	
  equivalent	
  of	
  40Gy.
genda Afternoon 1:20	
  -­‐	
  Morgensztern	
  NEW karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21	
  13:00:30 The	
  CREST	
  trial	
  design	
  is	
  flawed	
  because	
  the	
  radiation	
  dose	
  is	
  inadequate!	
  30	
  Gy	
  is	
  only	
  an	
  adequate	
  dose	
  for	
  a	
  quick	
  palliation.	
  If	
  one	
  wants	
  to	
  truly	
  evalua
genda Afternoon 1:20	
  -­‐	
  Morgensztern	
  NEW axs2115@bjc.org 2014-­‐06-­‐21	
  13:07:50 Does	
  afatinib	
  have	
  activity	
  in	
  egfr	
  mutant	
  patients	
  second	
  line	
  after	
  erlotinib?	
  How	
  about	
  in	
  t790	
  mutants	
  activity	
  of	
  afatinib?
genda Afternoon 1:20	
  -­‐	
  Morgensztern	
  NEW mmeadors@sfmc.net 2014-­‐06-­‐21	
  13:08:15 Management	
  strategy	
  for	
  EGFR	
  mutant	
  patient	
  progressing	
  on	
  Tarceva.
genda Afternoon 1:20	
  -­‐	
  Morgensztern	
  NEW syed.huq@mercy.net 2014-­‐06-­‐21	
  13:08:16
For	
  pts	
  with	
  t790m	
  mutations,	
  would	
  you	
  use	
  the	
  3rd	
  line	
  agents	
  in	
  the	
  upfront	
  setting?	
  If	
  not	
  available	
  
,chemo	
  or	
  afatinib.
genda Afternoon 1:20	
  -­‐	
  Morgensztern	
  NEW karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21	
  13:14:40 The	
  design	
  of	
  the	
  trial	
  is	
  flawed.	
  It	
  should	
  be	
  to	
  evaluate	
  the	
  extensive	
  disease	
  who	
  has	
  a	
  CR	
  after	
  chemo	
  radiation	
  ,	
  not	
  any	
  response.	
  If	
  patients	
  have	
  per
genda Afternoon 1:20	
  -­‐	
  Morgensztern	
  NEW karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21	
  13:20:31 Dr.	
  Morgen	
  stern	
  ,	
  if	
  you	
  want	
  to	
  ask	
  a	
  radiation	
  oncology	
  question,	
  	
  you	
  should	
  ask	
  your	
  Radiation	
  Oncology	
  colleagues	
  at	
  MIR.	
  Radiation	
  therapists	
  are	
  the
genda Afternoon 3:00	
  Wang-­‐Gillam karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21	
  14:49:48 I	
  assume	
  in	
  the	
  ARTIST	
  trial	
  the	
  total	
  dose	
  of	
  X	
  rat	
  is	
  4500	
  cGy	
  not	
  45	
  cGy	
  as	
  on	
  the	
  side.	
  Please	
  correct.
genda Afternoon 3:00	
  Wang-­‐Gillam jcarden@hsillc.com 2014-­‐06-­‐21	
  14:55:11 What	
  was	
  the	
  schedule	
  and	
  doses	
  of	
  the	
  ruxolitinib	
  when	
  use	
  Vs	
  placebo?
genda Afternoon 3:00	
  Wang-­‐Gillam jcarden@hsillc.com 2014-­‐06-­‐21	
  14:56:34 What	
  was	
  the	
  schedule	
  and	
  doses	
  of	
  the	
  ruxolitinib	
  when	
  use	
  Vs	
  placebo?	
  	
  	
  	
  (Single	
  agent)	
  
Questions SubmittedAttendee Registration
Activities used in this report:Activities used in this report:Activities used in this report:Activities used in this report:
Review	
  of	
  the	
  Presentations	
  from	
  the	
  	
  ASCO	
  2014	
  Annual	
  MeetingReview	
  of	
  the	
  Presentations	
  from	
  the	
  	
  ASCO	
  2014	
  Annual	
  MeetingReview	
  of	
  the	
  Presentations	
  from	
  the	
  	
  ASCO	
  2014	
  Annual	
  MeetingReview	
  of	
  the	
  Presentations	
  from	
  the	
  	
  ASCO	
  2014	
  Annual	
  Meeting
Intervals used in this report:Intervals used in this report:Intervals used in this report:Intervals used in this report:
Pre
Post
Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?
Answer Pre Pre	
  % Post Post	
  %
pure	
  hematology	
  (benign	
  and	
  malignant) 0 0 0 0
mostly	
  hematology	
  with	
  occasional	
  solid	
  tumors 5 11 0 0
Mostly	
  general	
  solid	
  tumor	
  oncology	
  with	
  some	
  hematology29 63 0 0
General	
  solid	
  tumor	
  oncology	
  (more	
  than	
  5	
  disease	
  types)7 15 0 0
Disease	
  focused	
  solid	
  tumor	
  oncology	
  (	
  5	
  disease	
  types	
  or	
  less)5 11 0 0
Total 46 100% 0 100%
Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?
Answer Pre Pre	
  % Post Post	
  %
The	
  number	
  of	
  new	
  agents	
  is	
  overwhelming	
  and	
  I	
  cannot	
  keep	
  up	
  with	
  the	
  new	
  agents11 23 0 0
The	
  number	
  of	
  new	
  agents	
  is	
  challenging	
  but	
  I	
  feel	
  comfortable	
  and	
  use	
  all	
  of	
  them21 45 0 0
The	
  number	
  of	
  new	
  agents	
  is	
  challenging,	
  so	
  I	
  have	
  limited	
  my	
  use	
  to	
  a	
  few	
  selected	
  agents15 32 0 0
Total 47 100% 0 100%
Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?
Answer Pre Pre	
  % Post Post	
  %
I	
  feel	
  comfortable	
  with	
  them	
  and	
  have	
  used	
  them	
  in	
  my	
  practice31 66 0 0
I	
  feel	
  comfortable	
  with	
  them	
  but	
  prefer	
  not	
  to	
  use	
  them	
  in	
  my	
  practice4 9 0 0
I	
  do	
  not	
  feel	
  comfortable	
  with	
  them	
  and	
  do	
  not	
  use	
  them	
  in	
  my	
  practice12 26 0 0
Total 47 100% 0 100%
Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?
Answer Pre Pre	
  % Post Post	
  %
Single	
  agent	
  ipilimumab 6 13 0 0
Single	
  agent	
  vemurafenib 9 19 0 0
Combination	
  of	
  trametinib	
  and	
  dabrafenib 11 23 0 0
Combination	
  of	
  ipilumumab	
  and	
  vemurafenib 3 6 0 0
Refer	
  patient	
  to	
  melanoma	
  expert	
  for	
  management19 40 0 0
Total 48 100% 0 100%
0
17.5
35
52.5
70
pure	
  hematology	
  (benign	
  and	
  malignant) General	
  solid	
  tumor	
  oncology	
  (more	
  than	
  5	
  disease	
  types)
00000
11
15
63
11
0
Which	
  best	
  describes	
  your	
  clinical	
  practice?
%
Pre	
  %
Post	
  %
0
12.5
25
37.5
50
The	
  number	
  of	
  new	
  agents	
  is	
  overwhelming	
  and	
  I	
  cannot	
  keep	
  up	
  with	
  the	
  new	
  agents
000
32
45
23
Which	
  best	
  reflects	
  your	
  feelings	
  about	
  the	
  rapid	
  expansion	
  of	
  “targeted”	
  therapies	
  in	
  oncology?
%
Pre	
  %
Post	
  %
0
17.5
35
52.5
70
I	
  feel	
  comfortable	
  with	
  them	
  and	
  have	
  used	
  them	
  in	
  my	
  practice I	
  do	
  not	
  feel	
  comfortable	
  with	
  them	
  and	
  do	
  not	
  use	
  them	
  in	
  my	
  practice
000
26
9
66
How	
  have	
  you	
  incorporated	
  immune	
  modulating	
  agents	
  into	
  your	
  practice?
%
Pre	
  %
Post	
  %
0
10
20
30
40
Single	
  agent	
  ipilimumab Combination	
  of	
  trametinib	
  and	
  dabrafenib Refer	
  patient	
  to	
  melanoma	
  expert	
  for	
  management
00000
40
6
23
19
13
You	
  are	
  referred	
  a	
  55	
  year	
  old	
  man	
  with	
  newly	
  diagnosed	
  V600E	
  mutated	
  metastatic	
  melanoma	
  with	
  exten
%
Pre	
  %
Post	
  %
Polling Results
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Em Array - Interactive Meeting Technology

  • 1. Introducing ARRAY OnQ iPad technology and on-site service that bring increased engagement, more participation and a whole new “Wow Factor” to your events.
  • 2. ARRAY OnQ runs on its own private network and server, so you won’t need to worry about unreliable and expensive hotel or venue Wi-Fi service. With ARRAY OnQ there are no issues with connectivity and all data and content are secure. The data collected using ARRAY OnQ goes into our highly powerful and user-friendly data analysis software. You can filter data sets, look at all your programming or focus on one meeting and evaluate impact. The system also creates a summary by slide of notes taken, questions asked, and slide rating. For over 10 years, EM has provided on-site technical service at over 5,000 events ranging in size from 10 people to 1,000. We get it. Welcome to ARRAY OnQ. Companies are being asked to improve interaction at their live events and collect quality data points to measure impact. Educational Measures developed ARRAY for this reason and we stand apart from our competitors because: About EM We develop and deploy event technolgies and top-end service for a wide variety of industries.
  • 3. ARRAY OnQ Features 4Stream and navigate live slides 4Built in polling 4Send questions to the moderator 4Take notes by slides 4Complete surveys 4Access electronic course manuals 4Provide summary reports to clients by slide or by participant +Improve interactivity and data collection! Our user interface is designed based on participant feedback so it is intuitive and easy-to-use. Slides display in real-time as presented, but can be navigated forward and backward through the presentation.
  • 4. ARRAY OnQ Features 4Stream and navigate live slides 4Built in polling 4Send questions to the moderator 4Take notes by slides 4Complete surveys 4Access electronic course manuals 4Provide summary reports to clients by slide or by participant +Improve interactivity and data collection! Can you navigate forward and backward through the live slides being shown? Real-time Questions: Attendees can ask questions while the meeting is in progress. Presenters will see it on their display.
  • 5. ARRAY OnQ Features 4Stream and navigate live slides 4Built in polling 4Send questions to the moderator 4Take notes by slides 4Complete surveys 4Access electronic course manuals 4Provide summary reports to clients by slide or by participant +Improve interactivity and data collection! Contact EM about our next meeting! ValuedClient@meeting.com ARRAY OnQ enables users to take notes – either by typing, or by writing or drawing with a stylus
  • 6. Polling: Ask questions at any time during a presentation. Attendees respond by simply tapping their choice. “The Add-on Impact of Mobile Applications in Learning Strategies: A  Review Study” states that infusing iPads in the live learning environ- ment is  fundamentally changing the ability of faculty to engage  par- ticipants, increase  interactivity, and improve efficiency in learning. A recent study found that mobile  technologies such as iPads have: = Increased participant  engagement in learning = Enabled collaborative  learning = Increased productivity and  efficiency during learning = All of the above Polling Question #1
  • 7. “The Add-on Impact of Mobile Applications in Learning Strategies: A  Review Study” states that infusing iPads in the live learning environment is  fundamentally changing the ability of faculty to engage  participants, increase  interactivity, and improve efficiency in learning. A recent study found that mobile  technologies such as iPads have: 1. Increased participant  engagement in learning 2. Enabled collaborative  learning 3. Increased productivity and  efficiency during learning 4. All of the above Polling results can be displayed immediately. Polling Question #1: Result
  • 8. Conduct surveys and evaluations at any time. Data collected is compatible with our analytics application. Survey
  • 9. Presenter Bios Christina Yieh Science Director Tellent Labs, Inc. Christina Yieh has been Science Director for Tellent Labs since 2011. Tellent is a world leader in microbiobial and genetic research with over 20 years of funded experience, working closely with 11 major universities and research institutions. Christina Yieh joined the company in 2008 and worked in a variety of positions in the US and in the UK. In 2009, she went to Paris, France as Science Development European Lead, manag- ing global research programs. She returned to New York in May 2011 as Science Director and since managed the development and launch of the division’s research paths. Prior to joining Tellent, Yieh worked at PharMeta as a Science and lab lead. She received a Masters of Science from Columbia University, New York and a Bachelors degree in Biology from John Cabot International College in Rome, Italy. Add all of your pertintent meeting information with our flexible tab system.
  • 10. Participants can rate each slide and the results can be viewed in the final engagement report. Tabs can be added and customized to suit your needs.
  • 11. Engagement Report: By-slide summary reports help you track particpation and effectiveness. Includes all notes taken and questions asked by slide.
  • 12. Additional Reports: ARRAY OnQ offers you a wide range of additional in-depth reports. genda Morning 1130  Vij sburstei@yahoo.com 2014-­‐06-­‐21  10:53:53 Will  a  pt  who  has  failed  post  transplant  maintenance  revlimid  qualify  for  the  anti  cd38  trial? genda Morning 1130  Vij syed.huq@mercy.net 2014-­‐06-­‐21  11:09:31 For  pts  with  17p  del  is  Ibrutinib  a  reasonable  option  in  the  first  line  setting genda Morning 1130  Vij axs2115@bjc.org 2014-­‐06-­‐21  11:09:50 Do  you  consider  gazyva  as  a  first  line  standard  of  care  now? genda Morning 1130  Vij ahusain01@hotmail.com 2014-­‐06-­‐21  11:11:20 Comment  about  ideally  sib  in  cll genda Morning 1130  Vij sburstei@yahoo.com 2014-­‐06-­‐21  11:11:57 Ibrutinib  in  myeloma? genda Morning 1130  Vij bethany.sleckman@mercy.net2014-­‐06-­‐21  11:12:36 How  do  you  assess  response  to  ibrutinib  in  CLL,  especially  in  patients  without  lymphadenopathy?   genda Morning 1130  Vij jcarden@hsillc.com 2014-­‐06-­‐21  11:13:12 In  cll  with  17p  deletion  will  you  combine  ibrutinib  with  rituxan genda Morning 1130  Vij mary@marymuscato.com 2014-­‐06-­‐21  11:13:42 Heard  about  PTH  PR.  Not  regular  PTH  causing  huge  hypercalcemia  in  CLL?    I  have  a  pt  w/  stag.  O  CLL.    Neg  for  cd38.     genda Morning 1130  Vij jcarden@hsillc.com 2014-­‐06-­‐21  11:20:09 Does  the  rituxan  clean  the  circulating  lymphocytes genda Morning TITLE  SLIDE karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21  08:28:47 How  to  follow  with  PETi  when    CMS  has  limited  a  total  of  3  PET  per  diagnosis  per  life  time? genda Morning TITLE  SLIDE axs2115@bjc.org 2014-­‐06-­‐21  09:55:25 Is  zytiga  just  a  less  toxic  ketoconazole  essentially? genda Morning TITLE  SLIDE dr.liana.makarian@ozarksmedicalcenter.com2014-­‐06-­‐21  09:56:23 What  was  the  median  age  for  trial  combining  taxotere  and  ADT. genda Morning 9:10  -­‐  Carson syed.huq@mercy.net 2014-­‐06-­‐21  08:46:04 How  do  oncologists  balance  responsibility  to  individual  patients  vs  responsible  stewardship  of  healthcare  costs  or  is  that  even  the  responsibility  of  the  indiv genda Morning 9:10  -­‐  Carson jmuscato@gmail.com 2014-­‐06-­‐21  08:54:00 Comment  re  hospitalization  of  NSCLC  patients:  a  lot  get  admitted  for  exacerbation  of  COPD.  These  patients  may  have  had  worse  overall  PS  to  begin  with.  Al genda Morning 9:10  -­‐  Carson karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21  08:56:57 Abst.  6519:  Is  it  possible  that  pts.  on  clinical  trials  are  watched  more  closely  than  real  world  pts.  so  most  neutropenic  fever  are  taken  care  of    earlier? genda Morning 9:10  -­‐  Carson arifbari2000@yahoo.com 2014-­‐06-­‐21  08:59:34 Could  you  comment  on  surveillance  imaging  on  non  small  cell  lung  cancer,  frequency  and  length  of  imaging,  and  CT  vs  PET?? genda Morning 9:10  -­‐  Carson karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21  09:00:33 Previous  Asb.  8502  showed  benefit  for  PET/CT  for  prediction  of  PRS    OS.  Since  CMS  has  limited  a  total  PET  of  3  per  diagnosis  per  life  time,  any  recommend genda Morning 9:10  -­‐  Carson jmuscato@gmail.com 2014-­‐06-­‐21  09:03:15 How  does  Watson  decide  if  those  12M  pages  are  really  valid  or  good  studies?   genda Morning 9:10  -­‐  Carson medicusaf4@att.net 2014-­‐06-­‐21  09:04:44 Explosion  of  oncology  meds,  treatments  -­‐  I  need  Watson  IBM  Now,  how  do  I  sign  up?? genda Morning 9:10  -­‐  Carson karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21  09:09:28 ASb.  6513:  is  it  possible  the  30%  of  stage  III  colon  pts.  Who  did  not  receive  FOLFOX  x  12  due  to    surgical  complications  /  bowel  obstruction,  those  pts.  Died  o genda Morning 8:30  -­‐  Bartlett lgiannone@aol.com 2014-­‐06-­‐21  07:53:17 What  maintenance  rituxan  schedule  do  you  recommend genda Morning 8:30  -­‐  Bartlett jmuscato@gmail.com 2014-­‐06-­‐21  08:20:25 Do  those  FL  patients  with  a  positive  PET  reflect  the  possibility  of  some  large  cell  components  vs.  just  response  to  therapy?  Re  8502 genda Morning 8:30  -­‐  Bartlett dr.liana.makarian@ozarksmedicalcenter.com2014-­‐06-­‐21  08:20:46 Does  it  mean  that  pet  negative  follicular  lymphoma  after  induction  does  not  need  maintenance  rituxan?   genda Morning 8:30  -­‐  Bartlett syed.huq@mercy.net 2014-­‐06-­‐21  08:23:37 In  pts  with  negative  pet  post  tax,  can  you  skip  maintenance  rituxan  since  OS  better  than  PRIMA genda Morning 9:50  -­‐  Picus jmaheshwari@yahoo.com 2014-­‐06-­‐21  09:21:30 Is  weekly  taxotere  is  equally  effective  and  better  tolerated? genda Morning 9:50  -­‐  Picus jward2@dom.wustl.edu 2014-­‐06-­‐21  09:25:41 Will  the  early  data  on  the  use  of  taxotere  in  the  first  line  setting  in  high  volume  disease  change  your  clinical  practice? genda Morning 9:50  -­‐  Picus medicusaf4@att.net 2014-­‐06-­‐21  09:48:26 Discordance  between  12-­‐core  prostate  biopsy  and  radical  prostatectomy  specimen.    I  have  seen  many  radically  removed  prostates  with  a  very  tiny  focus  of genda Afternoon 1540  Wartman karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21  15:27:29 I  have  a  recent  patient  presented  with  diagnosis  of  Sebaceous  carcinoma  of  the  (R)  facial/  mandibular  area    sebaceous  adenoma  of  abdominal  wall  are (1)  Please  explain  the  prevalence  of  pleomorphism  in  the  setting  of  Muir  Torre  syndrome; (2)  What  is  the  clinical  significance  of  pleomorphism  for  my  patient    his  family  members? genda Afternoon 2:00  -­‐  Sorscher  NEW jmaheshwari@yahoo.com 2014-­‐06-­‐21  13:38:45 When  we  will  use  neuadjuvant  folfox  in  locally  advanced  rectal  cancer  before  chemo  radiation? genda Afternoon 2:00  -­‐  Sorscher  NEW syed.huq@mercy.net 2014-­‐06-­‐21  13:42:49 Should  we  be  recommending  multigene  panels  which  many  companies  are  marketing  for  hereditary  cancers,  given  the  ls  pts  carrying  brca  mutations? genda Afternoon 2:00  -­‐  Sorscher  NEW jward2@dom.wustl.edu 2014-­‐06-­‐21  13:46:41 You  make  a  case  for  resection  of  the  primary  tumor  in  CRC  in  the  modern  era.    Shouldn't  we  do  a  randomized  clinical  trial? genda Afternoon 2:00  -­‐  Sorscher  NEW gajera@hotmail.com 2014-­‐06-­‐21  13:47:33 When  to  have  surgery  for  primary  in  metastatic  colon  cancer  .?  Before  chemo  ? genda Afternoon 2:00  -­‐  Sorscher  NEW jmaheshwari@yahoo.com 2014-­‐06-­‐21  13:49:05 Natural  history  of  stage  4  colon  cancer   Surgery  7-­‐8  months Fu  add  6  weeks iFL  17 Folfox  avast  in  24-­‐30  months How  can  surgery  patient  will  be  longer? genda Afternoon 2:00  -­‐  Sorscher  NEW jward2@dom.wustl.edu 2014-­‐06-­‐21  13:55:20 EORTC  22921  concluded  that  adjuvant  chemotherapy  is  unnecessary  in  patients  with  rectal  cancer  who  received  per  operative  chemo  radiotherapy.    Is  ther genda Afternoon 2:00  -­‐  Sorscher  NEW ahusain01@hotmail.com 2014-­‐06-­‐21  13:56:17 What  is  maxim  permissible  time  for  starting  adjuvant genda Afternoon 2:00  -­‐  Sorscher  NEW syed.huq@mercy.net 2014-­‐06-­‐21  13:59:47 Isnt  a  200  pt  study  underpowered  to  detect  a  difference  in  stage  2  colon  pts  for  folfox,  since  recurrence  rate  is  6% genda Afternoon 2:00  -­‐  Sorscher  NEW sburstei@yahoo.com 2014-­‐06-­‐21  14:00:16  Stage2msi  high  oxali  alone? genda Afternoon 12:10  -­‐  Linette jward2@dom.wustl.edu 2014-­‐06-­‐21  11:59:14 It  has  been  thought  that  immune  therapy  like  ipilimumab  is  more  effective  when  disease  is  present  to  prime  the  immune  system,  does  the  adjuvant  data  as genda Afternoon 12:10  -­‐  Linette axs2115@bjc.org 2014-­‐06-­‐21  11:59:16 Do  you  think  eortc  9008  should  have  used  High  dose  IFN  as  standard  arm  instead  of  placebo  against  ipilimumab? genda Afternoon 12:10  -­‐  Linette jcarden@hsillc.com 2014-­‐06-­‐21  12:00:43 Does  Ipilimumab  should  replace  interferon  in  adjuvant  therapy  of  stage  III  melanoma  ? genda Afternoon 12:10  -­‐  Linette lgiannone@aol.com 2014-­‐06-­‐21  12:03:28 What  is  the  role  of  IL-­‐2  in  metastatic  melanoma genda Afternoon 12:10  -­‐  Linette jcarden@hsillc.com 2014-­‐06-­‐21  12:17:52 What  is  yours  first,  second,  etc.  line  therapy  for  metastatic  malignant  melanoma?   genda Afternoon 12:10  -­‐  Linette axs2115@bjc.org 2014-­‐06-­‐21  12:22:10 Are  kras  and  Nras  mutations  mutually  exclusive? genda Afternoon 12:10  -­‐  Linette syed.huq@mercy.net 2014-­‐06-­‐21  12:25:09 Still  a  role  for  chemo  with  carbo-­‐taxol+Bev  without  braf  mutation? genda Afternoon 1:20  -­‐  Morgensztern  NEW rvij@dom.wustl.edu 2014-­‐06-­‐21  12:38:47 Is  Brazil  going  to  win  the  World  Cup? genda Afternoon 1:20  -­‐  Morgensztern  NEW jmaheshwari@yahoo.com 2014-­‐06-­‐21  12:49:17 After  this  PCI  study  would  you  offer  PCI? genda Afternoon 1:20  -­‐  Morgensztern  NEW karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21  12:51:26 PCI  dose  of  25  Gy  in  10  fx.  is  too  low  .  The  radiobiological    equivalent  of  only  30Gy  with  standard  fractionation  equivalent  of  40Gy. genda Afternoon 1:20  -­‐  Morgensztern  NEW karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21  13:00:30 The  CREST  trial  design  is  flawed  because  the  radiation  dose  is  inadequate!  30  Gy  is  only  an  adequate  dose  for  a  quick  palliation.  If  one  wants  to  truly  evalua genda Afternoon 1:20  -­‐  Morgensztern  NEW axs2115@bjc.org 2014-­‐06-­‐21  13:07:50 Does  afatinib  have  activity  in  egfr  mutant  patients  second  line  after  erlotinib?  How  about  in  t790  mutants  activity  of  afatinib? genda Afternoon 1:20  -­‐  Morgensztern  NEW mmeadors@sfmc.net 2014-­‐06-­‐21  13:08:15 Management  strategy  for  EGFR  mutant  patient  progressing  on  Tarceva. genda Afternoon 1:20  -­‐  Morgensztern  NEW syed.huq@mercy.net 2014-­‐06-­‐21  13:08:16 For  pts  with  t790m  mutations,  would  you  use  the  3rd  line  agents  in  the  upfront  setting?  If  not  available   ,chemo  or  afatinib. genda Afternoon 1:20  -­‐  Morgensztern  NEW karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21  13:14:40 The  design  of  the  trial  is  flawed.  It  should  be  to  evaluate  the  extensive  disease  who  has  a  CR  after  chemo  radiation  ,  not  any  response.  If  patients  have  per genda Afternoon 1:20  -­‐  Morgensztern  NEW karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21  13:20:31 Dr.  Morgen  stern  ,  if  you  want  to  ask  a  radiation  oncology  question,    you  should  ask  your  Radiation  Oncology  colleagues  at  MIR.  Radiation  therapists  are  the genda Afternoon 3:00  Wang-­‐Gillam karl.king@ncmc-­‐hospital.com2014-­‐06-­‐21  14:49:48 I  assume  in  the  ARTIST  trial  the  total  dose  of  X  rat  is  4500  cGy  not  45  cGy  as  on  the  side.  Please  correct. genda Afternoon 3:00  Wang-­‐Gillam jcarden@hsillc.com 2014-­‐06-­‐21  14:55:11 What  was  the  schedule  and  doses  of  the  ruxolitinib  when  use  Vs  placebo? genda Afternoon 3:00  Wang-­‐Gillam jcarden@hsillc.com 2014-­‐06-­‐21  14:56:34 What  was  the  schedule  and  doses  of  the  ruxolitinib  when  use  Vs  placebo?        (Single  agent)   Questions SubmittedAttendee Registration Activities used in this report:Activities used in this report:Activities used in this report:Activities used in this report: Review  of  the  Presentations  from  the    ASCO  2014  Annual  MeetingReview  of  the  Presentations  from  the    ASCO  2014  Annual  MeetingReview  of  the  Presentations  from  the    ASCO  2014  Annual  MeetingReview  of  the  Presentations  from  the    ASCO  2014  Annual  Meeting Intervals used in this report:Intervals used in this report:Intervals used in this report:Intervals used in this report: Pre Post Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice?Denes 1 - Which best describes your clinical practice? Answer Pre Pre  % Post Post  % pure  hematology  (benign  and  malignant) 0 0 0 0 mostly  hematology  with  occasional  solid  tumors 5 11 0 0 Mostly  general  solid  tumor  oncology  with  some  hematology29 63 0 0 General  solid  tumor  oncology  (more  than  5  disease  types)7 15 0 0 Disease  focused  solid  tumor  oncology  (  5  disease  types  or  less)5 11 0 0 Total 46 100% 0 100% Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology?Denes 2 - Which best reflects your feelings about the rapid expansion of “targeted” therapies in oncology? Answer Pre Pre  % Post Post  % The  number  of  new  agents  is  overwhelming  and  I  cannot  keep  up  with  the  new  agents11 23 0 0 The  number  of  new  agents  is  challenging  but  I  feel  comfortable  and  use  all  of  them21 45 0 0 The  number  of  new  agents  is  challenging,  so  I  have  limited  my  use  to  a  few  selected  agents15 32 0 0 Total 47 100% 0 100% Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice?Denes 3 - How have you incorporated immune modulating agents into your practice? Answer Pre Pre  % Post Post  % I  feel  comfortable  with  them  and  have  used  them  in  my  practice31 66 0 0 I  feel  comfortable  with  them  but  prefer  not  to  use  them  in  my  practice4 9 0 0 I  do  not  feel  comfortable  with  them  and  do  not  use  them  in  my  practice12 26 0 0 Total 47 100% 0 100% Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend?Denes 4 - You are referred a 55 year old man with newly diagnosed V600E mutated metastatic melanoma with extensive lung, liver , and bone metastases. Which of the following would you recommend? Answer Pre Pre  % Post Post  % Single  agent  ipilimumab 6 13 0 0 Single  agent  vemurafenib 9 19 0 0 Combination  of  trametinib  and  dabrafenib 11 23 0 0 Combination  of  ipilumumab  and  vemurafenib 3 6 0 0 Refer  patient  to  melanoma  expert  for  management19 40 0 0 Total 48 100% 0 100% 0 17.5 35 52.5 70 pure  hematology  (benign  and  malignant) General  solid  tumor  oncology  (more  than  5  disease  types) 00000 11 15 63 11 0 Which  best  describes  your  clinical  practice? % Pre  % Post  % 0 12.5 25 37.5 50 The  number  of  new  agents  is  overwhelming  and  I  cannot  keep  up  with  the  new  agents 000 32 45 23 Which  best  reflects  your  feelings  about  the  rapid  expansion  of  “targeted”  therapies  in  oncology? % Pre  % Post  % 0 17.5 35 52.5 70 I  feel  comfortable  with  them  and  have  used  them  in  my  practice I  do  not  feel  comfortable  with  them  and  do  not  use  them  in  my  practice 000 26 9 66 How  have  you  incorporated  immune  modulating  agents  into  your  practice? % Pre  % Post  % 0 10 20 30 40 Single  agent  ipilimumab Combination  of  trametinib  and  dabrafenib Refer  patient  to  melanoma  expert  for  management 00000 40 6 23 19 13 You  are  referred  a  55  year  old  man  with  newly  diagnosed  V600E  mutated  metastatic  melanoma  with  exten % Pre  % Post  % Polling Results
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