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LEUKEMIA
By: Kennedy Nevles & Stacy Studer
WHAT IS CANCER?

 Cancer is a group of more than 100 diseases.

 Abnormal cell in a part of the body that grows out of
control.

 Mutation in DNA.
CANCER OF BLOOD
          CELLS

 Cancer of blood cells.
    • Acute lymphocytic leukemia
    • Chronic lymphocytic leukemia
    • Acute myelocytic leukemia
    • Chronic myelocytic leukemia
    Starts in the cancer that forms blood
    Bone marrow makes abnormal white blood cells
    Early in chronic leukemia the leukemia cells can
      still do some of the work of normal white blood
      cells
LEUKEMIA

 Mutations that can trigger leukemia including, the
activation of oncogenes and the detection of tumor
suppressing genes.

 This disrupts the regulation of cell death, differential,
or division.

 It an occur spontaneously.
CAUSES

 No known cause

 Increase in risk with exposure to radiation, benzene,
and smoking
    • 20% of adult myeloid leukemia cases are linked to
      smoking.
PREVENTION




No Prevention!
SYMPTOMS

 Swollen Lymph nodes that usually don’t hurt

 Fevers or night sweats

 Frequent infection

 Feeling weak or tired

 Bleeding and bruising easily

 Weight loss for no reason
DIAGNOSIS

 Repeated complete blood counts

 Bone marrow examination

 Personal and family medical history.

 Bone marrow aspiration

 Bone marrow biopsy
TREATMENT

 Chemotherapy
   • Blood chemistry tests can detect degrees of
     liver and kidney damage
   X-Ray
   MRI
   Ultrasound
   Pharmaceutical medication
   Multi-drug chemotherapy regimen
INDIVIDUAL CONDUCTING
           CURRENT RESEARCH

 Pamela S Becker ,MD, PHD
•   Dr. Becker is a hematology oncologist who treats people with
    blood disorders, leukemia, lymphoma, multiple myeloma, and
    myelodysplastic syndrome.
•   How she became what she is…
•   At the age of 16 Becker attended a biochemistry summer
    program put on by the national Science Foundation. The year
    she graduated from high school she volunteered at a local
    hospital and worked in the chemistry lab
CURRENT RESEARCH

 New biological therapies

 New anticancer drugs, doses, and treatment schedules

 Combination of drugs, biological therapy, radiation
therapy, and stem cell transplantation.

 More genetic research
M O R E C U R R E N T R E S E A RC H ! !

 Supportive Care?

• Clinical trial are underway to find better ways of reducing
symptoms and side effects of current leukemia treatments in order to
improve patients comfort and quality of life.
SCHOLARSHIP AND
            COMMUNICATION

 What do the 4 types of leukemia get there names from?

• Each main type of leukemia is named according to the type of cell
that’s affected (a myeloid cell or a lymphoid cell) and whether the
disease begins in mature or immature cells.
SOURCES

 "Leukemia Cure, Causes, Diagnosis, Symptoms, Types and
Treatment on MedicineNet.com." MedicineNet. Web. 16 Nov. 2011.
<http://www.medicinenet.com/leukemia/article.htm>.

 Http://www.idph.state.il.us/cancer/factsheets/leukemia.htm

 http://en.wikipedia.org/wiki/Leukemia

 http://leukemia.emedtv.com/leukemia/leukemia-research.html

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Leukemia project 2[1]

  • 2. WHAT IS CANCER?  Cancer is a group of more than 100 diseases.  Abnormal cell in a part of the body that grows out of control.  Mutation in DNA.
  • 3. CANCER OF BLOOD CELLS  Cancer of blood cells. • Acute lymphocytic leukemia • Chronic lymphocytic leukemia • Acute myelocytic leukemia • Chronic myelocytic leukemia Starts in the cancer that forms blood Bone marrow makes abnormal white blood cells Early in chronic leukemia the leukemia cells can still do some of the work of normal white blood cells
  • 4. LEUKEMIA  Mutations that can trigger leukemia including, the activation of oncogenes and the detection of tumor suppressing genes.  This disrupts the regulation of cell death, differential, or division.  It an occur spontaneously.
  • 5. CAUSES  No known cause  Increase in risk with exposure to radiation, benzene, and smoking • 20% of adult myeloid leukemia cases are linked to smoking.
  • 7. SYMPTOMS  Swollen Lymph nodes that usually don’t hurt  Fevers or night sweats  Frequent infection  Feeling weak or tired  Bleeding and bruising easily  Weight loss for no reason
  • 8. DIAGNOSIS  Repeated complete blood counts  Bone marrow examination  Personal and family medical history.  Bone marrow aspiration  Bone marrow biopsy
  • 9. TREATMENT  Chemotherapy • Blood chemistry tests can detect degrees of liver and kidney damage X-Ray MRI Ultrasound Pharmaceutical medication Multi-drug chemotherapy regimen
  • 10. INDIVIDUAL CONDUCTING CURRENT RESEARCH  Pamela S Becker ,MD, PHD • Dr. Becker is a hematology oncologist who treats people with blood disorders, leukemia, lymphoma, multiple myeloma, and myelodysplastic syndrome. • How she became what she is… • At the age of 16 Becker attended a biochemistry summer program put on by the national Science Foundation. The year she graduated from high school she volunteered at a local hospital and worked in the chemistry lab
  • 11. CURRENT RESEARCH  New biological therapies  New anticancer drugs, doses, and treatment schedules  Combination of drugs, biological therapy, radiation therapy, and stem cell transplantation.  More genetic research
  • 12. M O R E C U R R E N T R E S E A RC H ! !  Supportive Care? • Clinical trial are underway to find better ways of reducing symptoms and side effects of current leukemia treatments in order to improve patients comfort and quality of life.
  • 13. SCHOLARSHIP AND COMMUNICATION  What do the 4 types of leukemia get there names from? • Each main type of leukemia is named according to the type of cell that’s affected (a myeloid cell or a lymphoid cell) and whether the disease begins in mature or immature cells.
  • 14. SOURCES  "Leukemia Cure, Causes, Diagnosis, Symptoms, Types and Treatment on MedicineNet.com." MedicineNet. Web. 16 Nov. 2011. <http://www.medicinenet.com/leukemia/article.htm>.  Http://www.idph.state.il.us/cancer/factsheets/leukemia.htm  http://en.wikipedia.org/wiki/Leukemia  http://leukemia.emedtv.com/leukemia/leukemia-research.html