SlideShare una empresa de Scribd logo
1 de 28
Descargar para leer sin conexión
Industry Relationships in
Medicine and Research
Eric G. Campbell, Ph.D.
Associate Professor
Disclaimer and Disclosure
• Comments do not represent the views of the
IHP, MGH, or HMS
• No relationships of any kind with any firm
whose products or services in any way
relate whatsoever to the life science
research enterprise
• Research funding is from the NIH and the
Greenwall Foundation, IMAP
Background: Definition of AIRs
Academic-Industry Relationships (AIRs):
Arrangements in which academic scientists,
administrators and physicians receive industry
resources in exchange for access to intellectual
property, research services, or access to patients,
medical students, residents or other physicians.
Institutional Academic Industry Relationships
(IAIRs): Arrangements when academic
institutions, or any of their senior officials, have a
financial relationship with or a financial interest in
a public or private company
Types of Relationships
•
Individual Research Relationships
– Grants and contracts,
– Consulting
– Gifts
– Equity/ownership positions
– Trips
– Samples
• Institutional
– Discretionary funds
– Equipment
– Buildings
– Programs
Thesis
• Relationships with industry are ubiquitous in all
aspects of academic medicine. These relationships
are not universally bad or good. They have both
risks and benefits. Banning industry relationships
is neither possible or advisable in the current
context. The challenge is to enact new policies and
procedures related to the disclosure and
management of these relationships such that the
benefits are achieved and the risks are limited or
eliminated. Failure to do so could have dire
consequences for the future of medicine.
Third-Year Medical Students’ Exposure to Various Types of
Drug Company Interactions AIRs are ubiquitous in the modern
life science enterprise...
26
51
34
42
51
87
89
90
94
97
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%
Attend workshop
Book donated
Another social event
Drug sample
Dinner
Grand rounds
Snack
Journal reprint
Small, non-ed gift
Lunch
Sierles et al JAMA 2005 294:1034-1042
AIRs are ubiquitous......
Academic-based Researchers
6%
24%
32%
21%
18%
1%0%
20%
40%
60%
Research
funding
Consultant Paid Speaker Scientific
advisory
board
Support for
students
Officer/
executive
Campbell, E.G., et al Survey of Academic Faculty 2007
AIRs are ubiquitous......
NIH Intramural Scientists and Investigators
17%
8%
16%
2%0%
20%
40%
60%
Research
funding
Consultant Paid Speaker Scientific
advisory
board
Support for
students
Officer/
executive
n/an/a
Campbell, E.G., et al Survey of NIH Intramural Faculty, 2008-9
AIRs are ubiquitous in the modern
life science enterprise......
Percentage of IRB Members
2%
10%
14%17%
26%
14%
7%
0%
20%
40%
60%
Research
funding
Pay-Attend
Meetings
Consultant Speakers
bureau
Scientific
advisory
board
Support for
students
Officer/
executive
Campbell, E.G., et al NEJM 2006 355(22):2321-2329
AIRs are ubiquitous in the modern
life science enterprise......
Percentage of IRB Chairs
7%
12%
29%
17% 17% 17%
1%0%
20%
40%
60%
Research
funding
Pay-Attend
Meetings
Consultant Speakers
bureau
Scientific
advisory
board
Support for
students
Officer/
executive
Campbell et al, unpublished data
AIRs are a fundamental part of the
modern life science enterprise...
Percentage of Department Chair Relationships
9%
14%
21%
28% 27%
27%
19% 16%
0%
20%
40%
60%
Honoraria-
Speaking
Paid
Consultant
Advisory
board
Research
funding
CME speaker Speakers
bureau
Subsidized
travel
Founder of
company
Campbell, E.G., et al JAMA 2007; 298 (15): 1779-1786
AIRs are ubiquitous in the modern
life science enterprise......
Percentage of Clinical and Non-Clinical
Departments
19%
36%
65%
51%
37%
30%
3%8%13%2%12%3%
0%
20%
40%
60%
80%
100%
Support for
CME
Food &
Beverage
Support for
residents
Support for
dept
seminars
Support for
travel
Unrestricted
funds
Campbell, E.G., et al JAMA 2007; 298 (15): 1779-1786
Clinical departments
Non-clinical departments
AIRs are ubiquitous in the modern
life science enterprise......
Percentage of Physicians
9%
18%
78% 83%
35%
15% 3%
0%
20%
40%
60%
80%
100%
Drug
samples
Food &
Beverage
Reimburse-
Meetings
Consulting
payments
Speakers
bureaus
Advisory
boards
Payments
for enroll
patients
Campbell et al NEJM 2007 356(17):742-750
AIRs are ubiquitous in the modern
life science enterprise.....
Percentage with any AIR
94%
60%
43%
36%
53%
0%
20%
40%
60%
80%
100%
Faculty
Researchers
IRB
Members
IRB Chairs Dept. Chairs Physicians
AIRs are ubiquitous in the modern
life science enterprise......
Departments with > 1 relationships
67%
80%
43%
0
10
20
30
40
50
60
70
80
90
All Clinical Depts Non-Clinical Depts
Campbell, E.G., et al JAMA 2007; 298 (15): 1779-1786
Other Relationships….
• Professional associations
• Guideline committees
• Purchasing agents
• FDA review committees
• Other government officials
• Trustees
• CME
• Other relationships you would not believe… (see
next 3 slides)
Background: Other Stuff
• Medtronic and Ms. Kelly
– UCLA dept. chair “like to be taken to Platinum Plus”
– VP clinical affairs made $450,000 charging his OR
time as consulting
– $25,000 to docs to ride on Mardi Gras float
– $15,000 for beads to throw from float
– Trip to “think tank” in Alaska staffed by fishing guides
– Adult companionship
– Helicopter skiing trips
– Fake patent royalties
– Involves more than 100 surgeons nationally
• Dr. Charles B. Nemeroff, chair of Emory University's
department of psychiatry:
– Failed to disclose ~ $500,000 he received from GlaxoSmithKline for
giving talks that promoted the company's drugs (The New York Times,
10/04/08)
– As the editor-in-chief of the journal, Depression and Anxiety, wrote a
“Dear Me” letter in 2000, indicating that he was paying himself $3,000 to
write an article to celebrated the 5th anniversary of the introduction of
Effexor, an antidepressant created by Wyeth (Wall Street Journal,
12/18/08)
• Nemeroff also billed Emory for $3,000 for this work, which was paid for
by a grant from Wyeth
• Bristol-Myers Squibb
– Paid over $515 million in 2007 to resolve allegations involving their drug
marketing and pricing practices (Department of Justice, 09/28/07)
• Physician kickbacks included: travel to luxurious resorts, illegal
remuneration (consulting fees, expense payment)
• Retail and wholesaler kickbacks: stocking allowances, price protection
payments, prebates, market share payments and free goods
• Pfizer
– Paid over $430 million in 2004 to illegal marketing charges for drug
Neurontin due to activities by Warner-Lambert (acquired by Pfizer in
2000) between 1996-2000 (Department of Justice, 06/2004)
• Paid physicians to attend “consulting meetings” at destinations such as Hawaii,
Florida and the 1996 Olympic Games in Atlanta
• Physicians paid to allow sales reps see patient with them to allow the drug reps to
offer off-label pro-Neurontin treatment advice
• Blackstone Medical
– Paid Arkansas neurosurgeon, Dr. Patrick Chan, (and other physicians) for
bogus consulting contracts, fake research studies and gifts (Boston Globe,
01/08)
• Schering-Plough (New York Times, 06/27/04)
– Sent physicians checks for $10,000 “in exchange for an attached
'consulting' agreement that required nothing other than his commitment to
prescribe the company's medicines”
AIRs have benefits...
• Funding to support research ($1.5 billion in 1995)
• Increased academic productivity
• Increased commercial productivity
– Patent applications, patents granted, licenses, start-ups, etc
• Increased access to resources
• Opportunity to participate in application of research
• Offset wage differential between industrial and non-
industrial sectors that will assist in recruitment an
retention of scientists and administrators
• Samples for poor people
AIRs have benefits...
• New drugs and medical devices
• Access to newest information
• Address under use of medications and
technology
• Free meals for physicians and staff
• Trips to nice places
• Tickets to sporting events
Relationships have risks…..
• Industry funding is limited in amount and short in
focus compared to other funding sources
• Secrecy in science
• Shifting focus of science away from basic research
• Bias in research
• Increased management and negotiation costs
• Perception of being “bought out”
• Conflicts of interest (surgical dept example)
Please estimate the effect, if any, of your personal financial
relationships with industry on:
11%
11%
14%
27%
20%
24%
88%
88%
83%
68%
74%
69%
1%
1%
2%
5%
5%
6%
0% 20% 40% 60% 80% 100%
Recruiting new faculty
Retaining current faculty
Securing internal resources
from your institution
Your personal financial status
Your department financial status
Bringing in industry sponosred
research grants & contracts
% Positive
% No effect
% Negative
N=270 Campbell, E.G., et al JAMA 2007; 298 (15): 1779-1786
Please assess the relative effects on each of the following types of
industry relationships with respect to a department’s ability to
pursue independent, unbiased research:
10%
18%
17%
7%
8%
21%
28%
12% 72%
45%
48%
72%
0% 20% 40% 60% 80% 100%
More than one of the below
Serves on board(s)
Consults for ≥ 1 company
Substantial ownership/role in
start-up(s)
TypeofRelationship
% Positive
% No effect
% Negative
N=450 Campbell, E.G., et al JAMA 2007; 298 (15): 1779-1786
Other things to know …..
• I am entitled to these things…
• Patients don’t care…
• Drug samples are for my poor patients…
• Information provided by drug reps tends to be
biased towards company products…
• We can’t educate medical students and residents
without these……
• Some companies differentially recruit cheerleaders
for drug sales jobs….
Manage relationships
• Disclosure
• Review disclosures in context of established institutional policies
and procedures
• Ban some relationships (but not all)
– Research relationships
• PI with equity in clinical trials
• Gifts to individual scientists
– Non research relationships
• No lunches, dinners, sporting tickets….
• Very little contact (if any) between medical students and residents and
industry
• Monitor relationships that need monitoring
• Ignore and pray
Failure to do so could have dire
consequences for the future of
the life science enterprise.
• Scandals
• Compromise of key values
– Biased education and research
• Human subjects concerns
• Increased governmental regulation
• Loss of public support for academic science
Policy Projections
• Scaling back/bans at medical schools and teaching
hospitals
• More public reporting
• Establishment of institutional level review boards
with external membership
• Companies images with public will continue to
fall
• Companies will become increasingly sly..
– Hotel lunches off campus
– Blurring of accredited and non-accredited CME

Más contenido relacionado

La actualidad más candente

Po bech02(1)
Po bech02(1)Po bech02(1)
Po bech02(1)BarryCRNA
 
Measuring success through improved attribution
Measuring success through improved attributionMeasuring success through improved attribution
Measuring success through improved attributionKristi Holmes
 
Carving a New Niche for Non-Profits: Filling the Translational Gap for Novel ...
Carving a New Niche for Non-Profits: Filling the Translational Gap for Novel ...Carving a New Niche for Non-Profits: Filling the Translational Gap for Novel ...
Carving a New Niche for Non-Profits: Filling the Translational Gap for Novel ...Life Sciences Network marcus evans
 
mHealth Israel_Washington University in St Louis / BJC Healthcare, Institute ...
mHealth Israel_Washington University in St Louis / BJC Healthcare, Institute ...mHealth Israel_Washington University in St Louis / BJC Healthcare, Institute ...
mHealth Israel_Washington University in St Louis / BJC Healthcare, Institute ...Levi Shapiro
 
GW SEAS Academic Expectations
GW SEAS Academic ExpectationsGW SEAS Academic Expectations
GW SEAS Academic Expectationsseasgrad
 
F&I: Mike Conlon - Death by 1,000 Cuts: Researcher Burden Up Close & Personal
F&I: Mike Conlon - Death by 1,000 Cuts: Researcher Burden Up Close & PersonalF&I: Mike Conlon - Death by 1,000 Cuts: Researcher Burden Up Close & Personal
F&I: Mike Conlon - Death by 1,000 Cuts: Researcher Burden Up Close & PersonalCASRAI
 
mHealth Israel_BJC Healthcare Health System Innovation Lab, Presentation by D...
mHealth Israel_BJC Healthcare Health System Innovation Lab, Presentation by D...mHealth Israel_BJC Healthcare Health System Innovation Lab, Presentation by D...
mHealth Israel_BJC Healthcare Health System Innovation Lab, Presentation by D...Levi Shapiro
 
Challenges in Clinical Trials Networks
Challenges in Clinical Trials NetworksChallenges in Clinical Trials Networks
Challenges in Clinical Trials NetworksUS Cochrane Center
 
Finding a Job and Negotiating an Agreement in Allergy/Immunology - AAAAI 2015
Finding a Job and Negotiating an Agreement in Allergy/Immunology - AAAAI 2015Finding a Job and Negotiating an Agreement in Allergy/Immunology - AAAAI 2015
Finding a Job and Negotiating an Agreement in Allergy/Immunology - AAAAI 2015Tao Le
 
mHealth Israel_Global STL overview
mHealth Israel_Global STL overviewmHealth Israel_Global STL overview
mHealth Israel_Global STL overviewLevi Shapiro
 
Visiting My Alma mater University of Cincinnati 20 April 2017
Visiting My Alma mater University of Cincinnati 20 April 2017Visiting My Alma mater University of Cincinnati 20 April 2017
Visiting My Alma mater University of Cincinnati 20 April 2017Ajaz Hussain
 
AERA 2010: A Steady State
AERA 2010: A Steady StateAERA 2010: A Steady State
AERA 2010: A Steady StateTom Perorazio
 
Translational researchfinal4whsla
Translational researchfinal4whslaTranslational researchfinal4whsla
Translational researchfinal4whslaAllan Barclay
 
Ethics CPD workshop
Ethics CPD workshopEthics CPD workshop
Ethics CPD workshopMichael Rowe
 
Cadth 2015 c2 new methods hta
Cadth 2015 c2 new methods htaCadth 2015 c2 new methods hta
Cadth 2015 c2 new methods htaCADTH Symposium
 
Academic Integrity — UNM Jump Start
Academic Integrity — UNM Jump StartAcademic Integrity — UNM Jump Start
Academic Integrity — UNM Jump StartJoseph Martinez
 
Employment Outlook for Science Professionals
Employment Outlook for Science ProfessionalsEmployment Outlook for Science Professionals
Employment Outlook for Science ProfessionalsKelly Services
 
So much evidence 1
So much evidence 1So much evidence 1
So much evidence 1Hesham Gaber
 

La actualidad más candente (18)

Po bech02(1)
Po bech02(1)Po bech02(1)
Po bech02(1)
 
Measuring success through improved attribution
Measuring success through improved attributionMeasuring success through improved attribution
Measuring success through improved attribution
 
Carving a New Niche for Non-Profits: Filling the Translational Gap for Novel ...
Carving a New Niche for Non-Profits: Filling the Translational Gap for Novel ...Carving a New Niche for Non-Profits: Filling the Translational Gap for Novel ...
Carving a New Niche for Non-Profits: Filling the Translational Gap for Novel ...
 
mHealth Israel_Washington University in St Louis / BJC Healthcare, Institute ...
mHealth Israel_Washington University in St Louis / BJC Healthcare, Institute ...mHealth Israel_Washington University in St Louis / BJC Healthcare, Institute ...
mHealth Israel_Washington University in St Louis / BJC Healthcare, Institute ...
 
GW SEAS Academic Expectations
GW SEAS Academic ExpectationsGW SEAS Academic Expectations
GW SEAS Academic Expectations
 
F&I: Mike Conlon - Death by 1,000 Cuts: Researcher Burden Up Close & Personal
F&I: Mike Conlon - Death by 1,000 Cuts: Researcher Burden Up Close & PersonalF&I: Mike Conlon - Death by 1,000 Cuts: Researcher Burden Up Close & Personal
F&I: Mike Conlon - Death by 1,000 Cuts: Researcher Burden Up Close & Personal
 
mHealth Israel_BJC Healthcare Health System Innovation Lab, Presentation by D...
mHealth Israel_BJC Healthcare Health System Innovation Lab, Presentation by D...mHealth Israel_BJC Healthcare Health System Innovation Lab, Presentation by D...
mHealth Israel_BJC Healthcare Health System Innovation Lab, Presentation by D...
 
Challenges in Clinical Trials Networks
Challenges in Clinical Trials NetworksChallenges in Clinical Trials Networks
Challenges in Clinical Trials Networks
 
Finding a Job and Negotiating an Agreement in Allergy/Immunology - AAAAI 2015
Finding a Job and Negotiating an Agreement in Allergy/Immunology - AAAAI 2015Finding a Job and Negotiating an Agreement in Allergy/Immunology - AAAAI 2015
Finding a Job and Negotiating an Agreement in Allergy/Immunology - AAAAI 2015
 
mHealth Israel_Global STL overview
mHealth Israel_Global STL overviewmHealth Israel_Global STL overview
mHealth Israel_Global STL overview
 
Visiting My Alma mater University of Cincinnati 20 April 2017
Visiting My Alma mater University of Cincinnati 20 April 2017Visiting My Alma mater University of Cincinnati 20 April 2017
Visiting My Alma mater University of Cincinnati 20 April 2017
 
AERA 2010: A Steady State
AERA 2010: A Steady StateAERA 2010: A Steady State
AERA 2010: A Steady State
 
Translational researchfinal4whsla
Translational researchfinal4whslaTranslational researchfinal4whsla
Translational researchfinal4whsla
 
Ethics CPD workshop
Ethics CPD workshopEthics CPD workshop
Ethics CPD workshop
 
Cadth 2015 c2 new methods hta
Cadth 2015 c2 new methods htaCadth 2015 c2 new methods hta
Cadth 2015 c2 new methods hta
 
Academic Integrity — UNM Jump Start
Academic Integrity — UNM Jump StartAcademic Integrity — UNM Jump Start
Academic Integrity — UNM Jump Start
 
Employment Outlook for Science Professionals
Employment Outlook for Science ProfessionalsEmployment Outlook for Science Professionals
Employment Outlook for Science Professionals
 
So much evidence 1
So much evidence 1So much evidence 1
So much evidence 1
 

Destacado

What Is Europe's Horizon 2020 Initiative?
What Is Europe's Horizon 2020 Initiative? What Is Europe's Horizon 2020 Initiative?
What Is Europe's Horizon 2020 Initiative? Ingemar Pongratz
 
Science Exchange - Measuring Research Efficiency & Quality
Science Exchange - Measuring Research Efficiency & QualityScience Exchange - Measuring Research Efficiency & Quality
Science Exchange - Measuring Research Efficiency & QualityScience Exchange
 
Maggots Hip 'n' Shouldered: Crowd Funding Academic Research ANU 2014
Maggots Hip 'n' Shouldered: Crowd Funding Academic Research ANU 2014Maggots Hip 'n' Shouldered: Crowd Funding Academic Research ANU 2014
Maggots Hip 'n' Shouldered: Crowd Funding Academic Research ANU 2014VeraQ Pty Ltd
 
Developing Cures with Less Time & Capital:A New Research Model to Accelerate ...
Developing Cures with Less Time & Capital:A New Research Model to Accelerate ...Developing Cures with Less Time & Capital:A New Research Model to Accelerate ...
Developing Cures with Less Time & Capital:A New Research Model to Accelerate ...Myelin Repair Foundation
 
Industry vsacademia 20110211
Industry vsacademia 20110211Industry vsacademia 20110211
Industry vsacademia 20110211Philip Bourne
 
Mini tutorial presentation
Mini tutorial presentationMini tutorial presentation
Mini tutorial presentationumesh.soni26
 
Leading Molecules to Market - An overview on licensing
 Leading Molecules to Market - An overview on licensing Leading Molecules to Market - An overview on licensing
Leading Molecules to Market - An overview on licensingBananaIP Counsels
 
Impact of Payer Policies on Pharmaceutical R&D
Impact of Payer Policies on Pharmaceutical R&DImpact of Payer Policies on Pharmaceutical R&D
Impact of Payer Policies on Pharmaceutical R&DOffice of Health Economics
 
Orphan Drug Report
Orphan Drug ReportOrphan Drug Report
Orphan Drug ReportBill Smith
 
Sunday (2) lipinski
Sunday (2) lipinskiSunday (2) lipinski
Sunday (2) lipinskiplmiami
 
Strategic R&D Outsourcing
Strategic R&D OutsourcingStrategic R&D Outsourcing
Strategic R&D OutsourcingNetraranjn
 
Conflict of interest_Dr. Mansij Biswas
Conflict of interest_Dr. Mansij BiswasConflict of interest_Dr. Mansij Biswas
Conflict of interest_Dr. Mansij BiswasMansij Biswas
 
Anda registration in us eu
Anda registration in us  euAnda registration in us  eu
Anda registration in us euPatel Parth
 
Horizon 2020 European Grants: Should Your Portfolio Companies Apply?
Horizon 2020 European Grants: Should Your Portfolio Companies Apply?Horizon 2020 European Grants: Should Your Portfolio Companies Apply?
Horizon 2020 European Grants: Should Your Portfolio Companies Apply?Zaz Ventures
 
Big Data in Biomedicine – An NIH Perspective
Big Data in Biomedicine – An NIH PerspectiveBig Data in Biomedicine – An NIH Perspective
Big Data in Biomedicine – An NIH PerspectivePhilip Bourne
 

Destacado (20)

Nursing funds
Nursing fundsNursing funds
Nursing funds
 
What Is Europe's Horizon 2020 Initiative?
What Is Europe's Horizon 2020 Initiative? What Is Europe's Horizon 2020 Initiative?
What Is Europe's Horizon 2020 Initiative?
 
Deep Dive Domino Mail Routing - SMTP Cookbook - DNUG Herbstkonferenz 2013
Deep Dive Domino Mail Routing - SMTP Cookbook - DNUG Herbstkonferenz 2013Deep Dive Domino Mail Routing - SMTP Cookbook - DNUG Herbstkonferenz 2013
Deep Dive Domino Mail Routing - SMTP Cookbook - DNUG Herbstkonferenz 2013
 
Flyer DDF
Flyer DDFFlyer DDF
Flyer DDF
 
Encuestas Enfermedades de Transmision Sexual
Encuestas Enfermedades de Transmision SexualEncuestas Enfermedades de Transmision Sexual
Encuestas Enfermedades de Transmision Sexual
 
Science Exchange - Measuring Research Efficiency & Quality
Science Exchange - Measuring Research Efficiency & QualityScience Exchange - Measuring Research Efficiency & Quality
Science Exchange - Measuring Research Efficiency & Quality
 
Maggots Hip 'n' Shouldered: Crowd Funding Academic Research ANU 2014
Maggots Hip 'n' Shouldered: Crowd Funding Academic Research ANU 2014Maggots Hip 'n' Shouldered: Crowd Funding Academic Research ANU 2014
Maggots Hip 'n' Shouldered: Crowd Funding Academic Research ANU 2014
 
Developing Cures with Less Time & Capital:A New Research Model to Accelerate ...
Developing Cures with Less Time & Capital:A New Research Model to Accelerate ...Developing Cures with Less Time & Capital:A New Research Model to Accelerate ...
Developing Cures with Less Time & Capital:A New Research Model to Accelerate ...
 
Industry vsacademia 20110211
Industry vsacademia 20110211Industry vsacademia 20110211
Industry vsacademia 20110211
 
Mini tutorial presentation
Mini tutorial presentationMini tutorial presentation
Mini tutorial presentation
 
Leading Molecules to Market - An overview on licensing
 Leading Molecules to Market - An overview on licensing Leading Molecules to Market - An overview on licensing
Leading Molecules to Market - An overview on licensing
 
Impact of Payer Policies on Pharmaceutical R&D
Impact of Payer Policies on Pharmaceutical R&DImpact of Payer Policies on Pharmaceutical R&D
Impact of Payer Policies on Pharmaceutical R&D
 
Orphan Drug Report
Orphan Drug ReportOrphan Drug Report
Orphan Drug Report
 
Sunday (2) lipinski
Sunday (2) lipinskiSunday (2) lipinski
Sunday (2) lipinski
 
Strategic R&D Outsourcing
Strategic R&D OutsourcingStrategic R&D Outsourcing
Strategic R&D Outsourcing
 
Conflict of interest_Dr. Mansij Biswas
Conflict of interest_Dr. Mansij BiswasConflict of interest_Dr. Mansij Biswas
Conflict of interest_Dr. Mansij Biswas
 
Anda registration in us eu
Anda registration in us  euAnda registration in us  eu
Anda registration in us eu
 
Ipmp corporate presentation
Ipmp corporate presentationIpmp corporate presentation
Ipmp corporate presentation
 
Horizon 2020 European Grants: Should Your Portfolio Companies Apply?
Horizon 2020 European Grants: Should Your Portfolio Companies Apply?Horizon 2020 European Grants: Should Your Portfolio Companies Apply?
Horizon 2020 European Grants: Should Your Portfolio Companies Apply?
 
Big Data in Biomedicine – An NIH Perspective
Big Data in Biomedicine – An NIH PerspectiveBig Data in Biomedicine – An NIH Perspective
Big Data in Biomedicine – An NIH Perspective
 

Similar a Eric Campbell

CAVERSTEM Corporate Presentation
CAVERSTEM Corporate PresentationCAVERSTEM Corporate Presentation
CAVERSTEM Corporate PresentationDonald Dickerson
 
CER 2016 Hernandez patient engagement
CER 2016 Hernandez patient engagementCER 2016 Hernandez patient engagement
CER 2016 Hernandez patient engagementCTSI at UCSF
 
Using alternative scholarly metrics to showcase the impact of your research: ...
Using alternative scholarly metrics to showcase the impact of your research: ...Using alternative scholarly metrics to showcase the impact of your research: ...
Using alternative scholarly metrics to showcase the impact of your research: ...SC CTSI at USC and CHLA
 
Conflict of Interests in Health Research
Conflict of Interests in Health ResearchConflict of Interests in Health Research
Conflict of Interests in Health ResearchDr Ghaiath Hussein
 
Nih dempwolf 20160408-v4
Nih dempwolf 20160408-v4Nih dempwolf 20160408-v4
Nih dempwolf 20160408-v4Scott Dempwolf
 
Zubin Master MedicReS World Congress 2015
Zubin Master MedicReS World Congress 2015Zubin Master MedicReS World Congress 2015
Zubin Master MedicReS World Congress 2015MedicReS
 
Northwestern U lecture
Northwestern U lectureNorthwestern U lecture
Northwestern U lectureJNeedham
 
John Needham Northwestern U lecture
John Needham Northwestern U lectureJohn Needham Northwestern U lecture
John Needham Northwestern U lectureJNeedham
 
Acrp Presentation Jan 2009
Acrp Presentation Jan 2009Acrp Presentation Jan 2009
Acrp Presentation Jan 2009thess1121
 
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...CTSI at UCSF
 
Scientific integrity
Scientific integrityScientific integrity
Scientific integrityscromartie123
 
Conflict of interest
Conflict of interestConflict of interest
Conflict of interestguest4c7388b
 
How to cultivate a research culture in the emergency department
How to cultivate a research culture in the emergency departmentHow to cultivate a research culture in the emergency department
How to cultivate a research culture in the emergency departmentkellyam18
 
Knowledge transfer, and evidence informed health policy-minster's meeting
Knowledge transfer, and evidence informed health policy-minster's meetingKnowledge transfer, and evidence informed health policy-minster's meeting
Knowledge transfer, and evidence informed health policy-minster's meetingDr Ghaiath Hussein
 
Career in clinical research
Career in clinical researchCareer in clinical research
Career in clinical researchaceindia367
 

Similar a Eric Campbell (20)

CAVERSTEM Corporate Presentation
CAVERSTEM Corporate PresentationCAVERSTEM Corporate Presentation
CAVERSTEM Corporate Presentation
 
After Fellowship
After FellowshipAfter Fellowship
After Fellowship
 
CER 2016 Hernandez patient engagement
CER 2016 Hernandez patient engagementCER 2016 Hernandez patient engagement
CER 2016 Hernandez patient engagement
 
Using alternative scholarly metrics to showcase the impact of your research: ...
Using alternative scholarly metrics to showcase the impact of your research: ...Using alternative scholarly metrics to showcase the impact of your research: ...
Using alternative scholarly metrics to showcase the impact of your research: ...
 
Conflict of Interests in Health Research
Conflict of Interests in Health ResearchConflict of Interests in Health Research
Conflict of Interests in Health Research
 
Paula Kim
Paula KimPaula Kim
Paula Kim
 
Nih dempwolf 20160408-v4
Nih dempwolf 20160408-v4Nih dempwolf 20160408-v4
Nih dempwolf 20160408-v4
 
Zubin Master MedicReS World Congress 2015
Zubin Master MedicReS World Congress 2015Zubin Master MedicReS World Congress 2015
Zubin Master MedicReS World Congress 2015
 
Playing for TEAM SCIENCE
Playing for TEAM SCIENCEPlaying for TEAM SCIENCE
Playing for TEAM SCIENCE
 
Northwestern U lecture
Northwestern U lectureNorthwestern U lecture
Northwestern U lecture
 
John Needham Northwestern U lecture
John Needham Northwestern U lectureJohn Needham Northwestern U lecture
John Needham Northwestern U lecture
 
Acrp Presentation Jan 2009
Acrp Presentation Jan 2009Acrp Presentation Jan 2009
Acrp Presentation Jan 2009
 
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...
Move Your Research Out of the Ivory Tower and Impact Health: Translating Earl...
 
Scientific integrity
Scientific integrityScientific integrity
Scientific integrity
 
Conflict of interest
Conflict of interestConflict of interest
Conflict of interest
 
Coi
CoiCoi
Coi
 
Conflict of interest
Conflict of interestConflict of interest
Conflict of interest
 
How to cultivate a research culture in the emergency department
How to cultivate a research culture in the emergency departmentHow to cultivate a research culture in the emergency department
How to cultivate a research culture in the emergency department
 
Knowledge transfer, and evidence informed health policy-minster's meeting
Knowledge transfer, and evidence informed health policy-minster's meetingKnowledge transfer, and evidence informed health policy-minster's meeting
Knowledge transfer, and evidence informed health policy-minster's meeting
 
Career in clinical research
Career in clinical researchCareer in clinical research
Career in clinical research
 

Más de Leonard Davis Institute of Health Economics

The Effects of Federal Parity on Substance Use Disorder Treatment_Andrew Epst...
The Effects of Federal Parity on Substance Use Disorder Treatment_Andrew Epst...The Effects of Federal Parity on Substance Use Disorder Treatment_Andrew Epst...
The Effects of Federal Parity on Substance Use Disorder Treatment_Andrew Epst...Leonard Davis Institute of Health Economics
 
Does a Wireless Incentive Structure Improve Retention, Subject Satisfaction a...
Does a Wireless Incentive Structure Improve Retention, Subject Satisfaction a...Does a Wireless Incentive Structure Improve Retention, Subject Satisfaction a...
Does a Wireless Incentive Structure Improve Retention, Subject Satisfaction a...Leonard Davis Institute of Health Economics
 
A Qualitative Study of Adverse Childhood Experiences of Low-Income Youth in P...
A Qualitative Study of Adverse Childhood Experiences of Low-Income Youth in P...A Qualitative Study of Adverse Childhood Experiences of Low-Income Youth in P...
A Qualitative Study of Adverse Childhood Experiences of Low-Income Youth in P...Leonard Davis Institute of Health Economics
 
The Intersection of Attitudes and Organizational Factors by Provider Type in ...
The Intersection of Attitudes and Organizational Factors by Provider Type in ...The Intersection of Attitudes and Organizational Factors by Provider Type in ...
The Intersection of Attitudes and Organizational Factors by Provider Type in ...Leonard Davis Institute of Health Economics
 
Doulas to fill the gap: a proposed model of doula delivery of cognitive-behav...
Doulas to fill the gap: a proposed model of doula delivery of cognitive-behav...Doulas to fill the gap: a proposed model of doula delivery of cognitive-behav...
Doulas to fill the gap: a proposed model of doula delivery of cognitive-behav...Leonard Davis Institute of Health Economics
 
A Glorious Mess: Implementing Evidence-Based Social Skills Interventions in P...
A Glorious Mess: Implementing Evidence-Based Social Skills Interventions in P...A Glorious Mess: Implementing Evidence-Based Social Skills Interventions in P...
A Glorious Mess: Implementing Evidence-Based Social Skills Interventions in P...Leonard Davis Institute of Health Economics
 
Healthcare System Supports for Internists Caring for Young Adult Patients wit...
Healthcare System Supports for Internists Caring for Young Adult Patients wit...Healthcare System Supports for Internists Caring for Young Adult Patients wit...
Healthcare System Supports for Internists Caring for Young Adult Patients wit...Leonard Davis Institute of Health Economics
 
Elderly Adults with Dementia and Young Adults with Developmental Disabilities...
Elderly Adults with Dementia and Young Adults with Developmental Disabilities...Elderly Adults with Dementia and Young Adults with Developmental Disabilities...
Elderly Adults with Dementia and Young Adults with Developmental Disabilities...Leonard Davis Institute of Health Economics
 
Is the quality of case management in a medical home associated with patient s...
Is the quality of case management in a medical home associated with patient s...Is the quality of case management in a medical home associated with patient s...
Is the quality of case management in a medical home associated with patient s...Leonard Davis Institute of Health Economics
 
CMHPSR/LDI Research Seminar_New Models for Childrens Mental Health Services D...
CMHPSR/LDI Research Seminar_New Models for Childrens Mental Health Services D...CMHPSR/LDI Research Seminar_New Models for Childrens Mental Health Services D...
CMHPSR/LDI Research Seminar_New Models for Childrens Mental Health Services D...Leonard Davis Institute of Health Economics
 
LDI Research Seminar 9_7_12 Eff ects of Federal Policy to Insure Young Adults...
LDI Research Seminar 9_7_12 Effects of Federal Policy to Insure Young Adults...LDI Research Seminar 9_7_12 Effects of Federal Policy to Insure Young Adults...
LDI Research Seminar 9_7_12 Eff ects of Federal Policy to Insure Young Adults...Leonard Davis Institute of Health Economics
 

Más de Leonard Davis Institute of Health Economics (20)

The Effects of Federal Parity on Substance Use Disorder Treatment_Andrew Epst...
The Effects of Federal Parity on Substance Use Disorder Treatment_Andrew Epst...The Effects of Federal Parity on Substance Use Disorder Treatment_Andrew Epst...
The Effects of Federal Parity on Substance Use Disorder Treatment_Andrew Epst...
 
Epstein,andy ispor poster_2013
Epstein,andy ispor poster_2013Epstein,andy ispor poster_2013
Epstein,andy ispor poster_2013
 
Does a Wireless Incentive Structure Improve Retention, Subject Satisfaction a...
Does a Wireless Incentive Structure Improve Retention, Subject Satisfaction a...Does a Wireless Incentive Structure Improve Retention, Subject Satisfaction a...
Does a Wireless Incentive Structure Improve Retention, Subject Satisfaction a...
 
Characterizing Emergency Department Utilization By A Population-based Cohort...
Characterizing Emergency Department Utilization  By A Population-based Cohort...Characterizing Emergency Department Utilization  By A Population-based Cohort...
Characterizing Emergency Department Utilization By A Population-based Cohort...
 
Non-Medically Indicated Delivery Prior to 39 Weeks Gestation in United State...
Non-Medically Indicated Delivery Prior to 39 Weeks Gestation  in United State...Non-Medically Indicated Delivery Prior to 39 Weeks Gestation  in United State...
Non-Medically Indicated Delivery Prior to 39 Weeks Gestation in United State...
 
A Qualitative Study of Adverse Childhood Experiences of Low-Income Youth in P...
A Qualitative Study of Adverse Childhood Experiences of Low-Income Youth in P...A Qualitative Study of Adverse Childhood Experiences of Low-Income Youth in P...
A Qualitative Study of Adverse Childhood Experiences of Low-Income Youth in P...
 
The Intersection of Attitudes and Organizational Factors by Provider Type in ...
The Intersection of Attitudes and Organizational Factors by Provider Type in ...The Intersection of Attitudes and Organizational Factors by Provider Type in ...
The Intersection of Attitudes and Organizational Factors by Provider Type in ...
 
Doulas to fill the gap: a proposed model of doula delivery of cognitive-behav...
Doulas to fill the gap: a proposed model of doula delivery of cognitive-behav...Doulas to fill the gap: a proposed model of doula delivery of cognitive-behav...
Doulas to fill the gap: a proposed model of doula delivery of cognitive-behav...
 
A Glorious Mess: Implementing Evidence-Based Social Skills Interventions in P...
A Glorious Mess: Implementing Evidence-Based Social Skills Interventions in P...A Glorious Mess: Implementing Evidence-Based Social Skills Interventions in P...
A Glorious Mess: Implementing Evidence-Based Social Skills Interventions in P...
 
Healthcare System Supports for Internists Caring for Young Adult Patients wit...
Healthcare System Supports for Internists Caring for Young Adult Patients wit...Healthcare System Supports for Internists Caring for Young Adult Patients wit...
Healthcare System Supports for Internists Caring for Young Adult Patients wit...
 
Elderly Adults with Dementia and Young Adults with Developmental Disabilities...
Elderly Adults with Dementia and Young Adults with Developmental Disabilities...Elderly Adults with Dementia and Young Adults with Developmental Disabilities...
Elderly Adults with Dementia and Young Adults with Developmental Disabilities...
 
Is the quality of case management in a medical home associated with patient s...
Is the quality of case management in a medical home associated with patient s...Is the quality of case management in a medical home associated with patient s...
Is the quality of case management in a medical home associated with patient s...
 
Comparison of HIV Testing with other Markers of Chronic Disease Screening 4_...
Comparison of HIV Testing with other  Markers of Chronic Disease Screening 4_...Comparison of HIV Testing with other  Markers of Chronic Disease Screening 4_...
Comparison of HIV Testing with other Markers of Chronic Disease Screening 4_...
 
Comparison of HIV Testing with other Markers of Chronic Disease Screening
Comparison of HIV Testing with other  Markers of Chronic Disease Screening Comparison of HIV Testing with other  Markers of Chronic Disease Screening
Comparison of HIV Testing with other Markers of Chronic Disease Screening
 
High Value Cost Conscious Care: Is it Rationing or Rational Care? 1_11_13
High Value Cost Conscious Care: Is it Rationing or Rational Care? 1_11_13High Value Cost Conscious Care: Is it Rationing or Rational Care? 1_11_13
High Value Cost Conscious Care: Is it Rationing or Rational Care? 1_11_13
 
LDI Research Seminar with Art Kellermann, MD, MPH 11_28_12
LDI Research Seminar with Art Kellermann, MD, MPH 11_28_12LDI Research Seminar with Art Kellermann, MD, MPH 11_28_12
LDI Research Seminar with Art Kellermann, MD, MPH 11_28_12
 
CMHPSR/LDI Research Seminar_New Models for Childrens Mental Health Services D...
CMHPSR/LDI Research Seminar_New Models for Childrens Mental Health Services D...CMHPSR/LDI Research Seminar_New Models for Childrens Mental Health Services D...
CMHPSR/LDI Research Seminar_New Models for Childrens Mental Health Services D...
 
LDI Research Seminar 9_7_12 Eff ects of Federal Policy to Insure Young Adults...
LDI Research Seminar 9_7_12 Effects of Federal Policy to Insure Young Adults...LDI Research Seminar 9_7_12 Effects of Federal Policy to Insure Young Adults...
LDI Research Seminar 9_7_12 Eff ects of Federal Policy to Insure Young Adults...
 
LDI Poster Template
LDI Poster TemplateLDI Poster Template
LDI Poster Template
 
LDI Charles Leighton Memorial Lecture with Mark Chassin, MD 5_4_12
LDI Charles Leighton Memorial Lecture with Mark Chassin, MD  5_4_12LDI Charles Leighton Memorial Lecture with Mark Chassin, MD  5_4_12
LDI Charles Leighton Memorial Lecture with Mark Chassin, MD 5_4_12
 

Eric Campbell

  • 1. Industry Relationships in Medicine and Research Eric G. Campbell, Ph.D. Associate Professor
  • 2. Disclaimer and Disclosure • Comments do not represent the views of the IHP, MGH, or HMS • No relationships of any kind with any firm whose products or services in any way relate whatsoever to the life science research enterprise • Research funding is from the NIH and the Greenwall Foundation, IMAP
  • 3. Background: Definition of AIRs Academic-Industry Relationships (AIRs): Arrangements in which academic scientists, administrators and physicians receive industry resources in exchange for access to intellectual property, research services, or access to patients, medical students, residents or other physicians. Institutional Academic Industry Relationships (IAIRs): Arrangements when academic institutions, or any of their senior officials, have a financial relationship with or a financial interest in a public or private company
  • 4. Types of Relationships • Individual Research Relationships – Grants and contracts, – Consulting – Gifts – Equity/ownership positions – Trips – Samples • Institutional – Discretionary funds – Equipment – Buildings – Programs
  • 5. Thesis • Relationships with industry are ubiquitous in all aspects of academic medicine. These relationships are not universally bad or good. They have both risks and benefits. Banning industry relationships is neither possible or advisable in the current context. The challenge is to enact new policies and procedures related to the disclosure and management of these relationships such that the benefits are achieved and the risks are limited or eliminated. Failure to do so could have dire consequences for the future of medicine.
  • 6. Third-Year Medical Students’ Exposure to Various Types of Drug Company Interactions AIRs are ubiquitous in the modern life science enterprise... 26 51 34 42 51 87 89 90 94 97 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Attend workshop Book donated Another social event Drug sample Dinner Grand rounds Snack Journal reprint Small, non-ed gift Lunch Sierles et al JAMA 2005 294:1034-1042
  • 7. AIRs are ubiquitous...... Academic-based Researchers 6% 24% 32% 21% 18% 1%0% 20% 40% 60% Research funding Consultant Paid Speaker Scientific advisory board Support for students Officer/ executive Campbell, E.G., et al Survey of Academic Faculty 2007
  • 8. AIRs are ubiquitous...... NIH Intramural Scientists and Investigators 17% 8% 16% 2%0% 20% 40% 60% Research funding Consultant Paid Speaker Scientific advisory board Support for students Officer/ executive n/an/a Campbell, E.G., et al Survey of NIH Intramural Faculty, 2008-9
  • 9. AIRs are ubiquitous in the modern life science enterprise...... Percentage of IRB Members 2% 10% 14%17% 26% 14% 7% 0% 20% 40% 60% Research funding Pay-Attend Meetings Consultant Speakers bureau Scientific advisory board Support for students Officer/ executive Campbell, E.G., et al NEJM 2006 355(22):2321-2329
  • 10. AIRs are ubiquitous in the modern life science enterprise...... Percentage of IRB Chairs 7% 12% 29% 17% 17% 17% 1%0% 20% 40% 60% Research funding Pay-Attend Meetings Consultant Speakers bureau Scientific advisory board Support for students Officer/ executive Campbell et al, unpublished data
  • 11. AIRs are a fundamental part of the modern life science enterprise... Percentage of Department Chair Relationships 9% 14% 21% 28% 27% 27% 19% 16% 0% 20% 40% 60% Honoraria- Speaking Paid Consultant Advisory board Research funding CME speaker Speakers bureau Subsidized travel Founder of company Campbell, E.G., et al JAMA 2007; 298 (15): 1779-1786
  • 12. AIRs are ubiquitous in the modern life science enterprise...... Percentage of Clinical and Non-Clinical Departments 19% 36% 65% 51% 37% 30% 3%8%13%2%12%3% 0% 20% 40% 60% 80% 100% Support for CME Food & Beverage Support for residents Support for dept seminars Support for travel Unrestricted funds Campbell, E.G., et al JAMA 2007; 298 (15): 1779-1786 Clinical departments Non-clinical departments
  • 13. AIRs are ubiquitous in the modern life science enterprise...... Percentage of Physicians 9% 18% 78% 83% 35% 15% 3% 0% 20% 40% 60% 80% 100% Drug samples Food & Beverage Reimburse- Meetings Consulting payments Speakers bureaus Advisory boards Payments for enroll patients Campbell et al NEJM 2007 356(17):742-750
  • 14. AIRs are ubiquitous in the modern life science enterprise..... Percentage with any AIR 94% 60% 43% 36% 53% 0% 20% 40% 60% 80% 100% Faculty Researchers IRB Members IRB Chairs Dept. Chairs Physicians
  • 15. AIRs are ubiquitous in the modern life science enterprise...... Departments with > 1 relationships 67% 80% 43% 0 10 20 30 40 50 60 70 80 90 All Clinical Depts Non-Clinical Depts Campbell, E.G., et al JAMA 2007; 298 (15): 1779-1786
  • 16. Other Relationships…. • Professional associations • Guideline committees • Purchasing agents • FDA review committees • Other government officials • Trustees • CME • Other relationships you would not believe… (see next 3 slides)
  • 17. Background: Other Stuff • Medtronic and Ms. Kelly – UCLA dept. chair “like to be taken to Platinum Plus” – VP clinical affairs made $450,000 charging his OR time as consulting – $25,000 to docs to ride on Mardi Gras float – $15,000 for beads to throw from float – Trip to “think tank” in Alaska staffed by fishing guides – Adult companionship – Helicopter skiing trips – Fake patent royalties – Involves more than 100 surgeons nationally
  • 18. • Dr. Charles B. Nemeroff, chair of Emory University's department of psychiatry: – Failed to disclose ~ $500,000 he received from GlaxoSmithKline for giving talks that promoted the company's drugs (The New York Times, 10/04/08) – As the editor-in-chief of the journal, Depression and Anxiety, wrote a “Dear Me” letter in 2000, indicating that he was paying himself $3,000 to write an article to celebrated the 5th anniversary of the introduction of Effexor, an antidepressant created by Wyeth (Wall Street Journal, 12/18/08) • Nemeroff also billed Emory for $3,000 for this work, which was paid for by a grant from Wyeth • Bristol-Myers Squibb – Paid over $515 million in 2007 to resolve allegations involving their drug marketing and pricing practices (Department of Justice, 09/28/07) • Physician kickbacks included: travel to luxurious resorts, illegal remuneration (consulting fees, expense payment) • Retail and wholesaler kickbacks: stocking allowances, price protection payments, prebates, market share payments and free goods
  • 19. • Pfizer – Paid over $430 million in 2004 to illegal marketing charges for drug Neurontin due to activities by Warner-Lambert (acquired by Pfizer in 2000) between 1996-2000 (Department of Justice, 06/2004) • Paid physicians to attend “consulting meetings” at destinations such as Hawaii, Florida and the 1996 Olympic Games in Atlanta • Physicians paid to allow sales reps see patient with them to allow the drug reps to offer off-label pro-Neurontin treatment advice • Blackstone Medical – Paid Arkansas neurosurgeon, Dr. Patrick Chan, (and other physicians) for bogus consulting contracts, fake research studies and gifts (Boston Globe, 01/08) • Schering-Plough (New York Times, 06/27/04) – Sent physicians checks for $10,000 “in exchange for an attached 'consulting' agreement that required nothing other than his commitment to prescribe the company's medicines”
  • 20. AIRs have benefits... • Funding to support research ($1.5 billion in 1995) • Increased academic productivity • Increased commercial productivity – Patent applications, patents granted, licenses, start-ups, etc • Increased access to resources • Opportunity to participate in application of research • Offset wage differential between industrial and non- industrial sectors that will assist in recruitment an retention of scientists and administrators • Samples for poor people
  • 21. AIRs have benefits... • New drugs and medical devices • Access to newest information • Address under use of medications and technology • Free meals for physicians and staff • Trips to nice places • Tickets to sporting events
  • 22. Relationships have risks….. • Industry funding is limited in amount and short in focus compared to other funding sources • Secrecy in science • Shifting focus of science away from basic research • Bias in research • Increased management and negotiation costs • Perception of being “bought out” • Conflicts of interest (surgical dept example)
  • 23. Please estimate the effect, if any, of your personal financial relationships with industry on: 11% 11% 14% 27% 20% 24% 88% 88% 83% 68% 74% 69% 1% 1% 2% 5% 5% 6% 0% 20% 40% 60% 80% 100% Recruiting new faculty Retaining current faculty Securing internal resources from your institution Your personal financial status Your department financial status Bringing in industry sponosred research grants & contracts % Positive % No effect % Negative N=270 Campbell, E.G., et al JAMA 2007; 298 (15): 1779-1786
  • 24. Please assess the relative effects on each of the following types of industry relationships with respect to a department’s ability to pursue independent, unbiased research: 10% 18% 17% 7% 8% 21% 28% 12% 72% 45% 48% 72% 0% 20% 40% 60% 80% 100% More than one of the below Serves on board(s) Consults for ≥ 1 company Substantial ownership/role in start-up(s) TypeofRelationship % Positive % No effect % Negative N=450 Campbell, E.G., et al JAMA 2007; 298 (15): 1779-1786
  • 25. Other things to know ….. • I am entitled to these things… • Patients don’t care… • Drug samples are for my poor patients… • Information provided by drug reps tends to be biased towards company products… • We can’t educate medical students and residents without these…… • Some companies differentially recruit cheerleaders for drug sales jobs….
  • 26. Manage relationships • Disclosure • Review disclosures in context of established institutional policies and procedures • Ban some relationships (but not all) – Research relationships • PI with equity in clinical trials • Gifts to individual scientists – Non research relationships • No lunches, dinners, sporting tickets…. • Very little contact (if any) between medical students and residents and industry • Monitor relationships that need monitoring • Ignore and pray
  • 27. Failure to do so could have dire consequences for the future of the life science enterprise. • Scandals • Compromise of key values – Biased education and research • Human subjects concerns • Increased governmental regulation • Loss of public support for academic science
  • 28. Policy Projections • Scaling back/bans at medical schools and teaching hospitals • More public reporting • Establishment of institutional level review boards with external membership • Companies images with public will continue to fall • Companies will become increasingly sly.. – Hotel lunches off campus – Blurring of accredited and non-accredited CME