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MCQ on bleeding in
          early pregnancy



    DR
Manal Behery
  Zagazig
 University
   2013
               med-ed-online
Abortion




       med-ed-online
1-What is wrong about recurrent abortion?

A-HSG is the best method to R/O anatomical
  etiologies
B-HSG is recommended several weeks after
  operative hysteroscopy
C-vaginal ultrasonography and MRI are the best
  techniques to detect anatomical defects
D-Septated uterus is the most common
  anatomical cause of recurrent abortion
Ans:A                 med-ed-online
2- A 20yo, Rh -ve and unsensitised woman
has missed miscarriage of 10wks all are
true except

A- Anti-D immunoglobulin should be
  administered if surgical evacuation is
  performed
B-Anti-D immunoglobulin is unnecessary
  after medical evacuation
C- products of conception should be sent for
  histological examination to exclude molar
  tissue
Ans:B               med-ed-online
Recurrent abortion tests
•   Karyotype
•   HSG
•   Luteal phase biopsy of endometrium
•   TSH and prolactin level
•   ACL antibodies
•   LAC (lupus anticoagulant)
•   CBC

                    med-ed-online
Forcases of abortion without
For   cases of abortion without
 fever:
fever:
 Doxy 100 mg bid
Doxy 100 mg bid
 or
or
 tetracycline 250 mg qid
tetracycline 250 mg qid
 for 5-7 days
for 5-7 days
             med-ed-online
3-What is wrong about postabortal or
“redo” syndrome?
A- It is a complication of suction curettage
B- It is a painful cramp in the first 2 hours
  after curettage
C-uterine bleeding is less than expected
D-treatment is D&C under anesthesia

Ans:D

                    med-ed-online
4- During a sharp curettage of an incomplete
abortion uterine is perforated. What is the
first step of management?
A- curettage should be completed and patient
  should remain under observation
B-laparatomy
C-curettage should be stopped and patient should
  remain under observation
D- if there is no hemorrhage in the first 24 hours
  after operation, the patient can be discharged
Ans:B


                     med-ed-online
5-The clinical findings of a woman with GA=8 wks
with the chief complaint of hemorrhage and clot
passing is an open int os Uterine size about 8 wks
and no bleeding. What should be done ?

A-No treatment is needed because abortion
  is complete
B-it is a case of threatened abortion
C-it is an inevitable abortion
D-Abdominal sonography

Ans:D
                     med-ed-online
6- A woman has undergone elective abortion one
week ago. Now she comes to the clinic with the
chief complaint of hemorrhage. In PE cervix is
closed, uterine is contracted with no tenderness.
Her temperature is normal . What is the best
treatment?
A-Doxy 100 mg bid for two weeks
B-clinda +genta
C-observation and check of Hb and Hct
D-hormone therapy

Ans:D                 med-ed-online
7- What is the most likely cause of abortion in a 27 year old
woman with the past history of two abortions in 10 wks and
one in 15 wks with normal Karyotype conceptus?

A- endocrine
B-immunological
C-anatomic
D-infectious

Ans:B
The treatment of immunological recurrent
  abortion is low dose Heparin sc 5000 units
  bid+Aspirin 80 mg daily
                          med-ed-online
8-What should be done for a woman 22 years old
who has undergone suction curettage and now
suffers severe pelvic cramps , sweating and
tachycardia. Her uterus is large and tender. She
also has spotting.

A-observation and oxytocin
B-laparatomy
CDilation and suction curettage without
  anesthesia
D- CT scan

Ans:C
                     med-ed-online
9-What is the best way of pregnancy termination in
a bicornuate uterus with a 14 w fetal death?


A-dilatation and curettage under US
B-uterotonic drugs
C-dilatation and curettage under laparascopy
D-hysterotomy

Ans:B

                     med-ed-online
Ectopic
Pregnancy
10-Where is the discriminatory zone?

A-3000 IU/L HCG + abdominal US
B-1000-1500 IU/L HCG + vaginal US
C-a constant value of HCG for any type of
  US
D-in multiple pregnancy it is lower than
  singleton pregnancy
Ans:B

                  med-ed-online
Beta HCG below 2000+
      no visible intrauterine sac+
      mass in tube below 3.5 cm
      ______________________
Repeat of beta HCG q 48 h
A-If a dead IP is confirmed (beta HCG increase less
than 50% or below 1000mIu/mL- P below 5 ng/mL +
visible intrauterine sac) then curettage

 B-If EP is confirmed (beta HCG more than 2000 and
mass >3.5 cm) then laparascopy
C-If a dead IP and EP is confirmed (beta HCG more
than 2000 and mass < 3.5 cm) then MTX

FETUS SHOULD BE VISIBLE ON DAY 45 OF
                  med-ed-online
GESTATION
Indication of MTX for EP
• Hemodynamic stability
• No intra uterine pregnancy
• Max sac diameter not equal or more than
  4 cm




                  med-ed-online
11-What is your management of a 36 year old woman who
is pregnant after primary infertity. She is referring to you for
spotting and hypogastric pain, beta HCG is 1500 mu/l and
ultrasound of uterus and ovaries are normal.

A-laparatomy
B-laparascopy
C-repeat of vaginal sonography several
  days later
D-progesterone measurement

Ans:C
                           med-ed-online
12-A 30 year old woman has become pregnant
after 5 years of infertility with ovulation induction
and a history of EP in the right tube 2 years ago.
She has undergone laparatomy for ruptured right
fallopian tube. What is the best technique for this
surgery?
A-Milking
B-linear salpingectomy
C-right tube salpingectomy
D-segmantal excision and delayed
 anastomosis

Ans:C                  med-ed-online
13- In a woman 31 years old who has undergone
salpingectomy two weeks ago for EP, HCG level is
increasing. What is your management?

A-MTX
B-transvaginal sonography
C-salpingectomy
D-chest x-ray

Ans:B

                    med-ed-online
14-RU486 can not attach to:

A-Progesterone receptor
B-androgen receptor
C-glucocorticosteroid receptor
D-estrogen receptor

Ans: D


                   med-ed-online
15-What is your management for a woman with :
HR=120 BP=80/60 mmHg T=37.5 c uterine
size=8 wks beta HCG=2500 mIU/mL and no
intrauterine pregnancy in sonography?

A-Laparatomy
B- laparascopy
C- D&C
D-serum progesterone

Ans:A
                    med-ed-online
Adenexal mass< 3.5 cm MTX

      Adenexal mass=> 3.5 cm ->
      laparascopy
>laparatomy
      Uncertain US + beta HCG increase
      less than 50% -> D&C

      Unstable conditions->laparatomy


                  med-ed-online
16- which is a predisposing factor for ovarian EP?

A-PID
B-infertility history
C-DES exposure
D-present IUD

Ans:D


                        med-ed-online
17-All are among indications for conservative
management of EP except::

A-ovarian EP
B-reduced HCG level
C-sac of less than 3 cm
D-lack of noticeable intra abdominal
  hemorrhage

Ans:A

                     med-ed-online
• Gestational trophoblastic disease




       Vesiculaer mole




                    med-ed-online
CASE STUDY
• A 21 year old woman comes in for first
  prenatal visit .Her LMP was 12 wks ago of
  which she was certain .
• Upon examination you noted 20 wks
  uterus ,therefore an US is performed and
  revealed bilaterally enlarged adnexa and a
  snowstorm pattern in the uterus. You
  suspect a molar pregnancy what is your
  next step ?
                   med-ed-online
You should order B-HCG in
            serum
• The result comes back as 100,000
  confirming your suspicion of a complete
  mole




• Of course the definite diagnosis will not be
  made until a D&C is performed
                    med-ed-online
18-Clinical features that distinguish a
complete mole from a partiel mole are

A-Gestational age between 8-16 wks
B-B HCG level 100,000
C-Uterine size that is larger for gestational
  age
D- Ultrasonographic features
E- all of the above
Ans:D
                    med-ed-online
19-To optimally prepare for D&C you
should take the following steps except

A-type and cross match for blood
B- full operating room setting
C- suction cannula
D-General anathesia
E- A 22 gauge intravenous access

Ans:E
                 med-ed-online
20-With respect to complete mole all are
true except

• A- Complete moles have 46XX karyotype
•
  B-Maternal serum AFP levels are undetectable
  in complete moles as there no fetal parts
•
  C-Medical evacuation using prostaglandins and
  oxytocin is the recommended treatment
•
  D-During surgical evacuation, oxytocin infusion
  shouldn’t be commenced before the uterus is
  empty
                      med-ed-online
• ANS         C
21- All of the following are associated
with an increased risk of malignant
change in a woman with vesicular molar
PPREPREpregnancy except
• A-maternal age > 39years HSG
• B-woman with BG-A with a partner of
  BG-O
  TSH and prolactin level
• C-Complete mole more than partial
  moles
• D- smoking
• Ans:D         med-ed-online
Suction evacuation under general
   anathesia was performed
     How can you
     councel this case
     regarding
     contraceptive
     advice before the
     next pregnancy
             med-ed-online
22-Which is true regarding
  contraception after molar evacuation ?

  A-Women should be advised not to conceive
  until HCG levels have been normal for 12 mths
B-Use of the COCP after HCG levels have
  returned to normal is associated with increased
  need for chemotherapy
C-Use of IUDs in contraindicated until after HCG
  levels have returned to normal
Ans:C
                     med-ed-online
23-Which is true regarding molar
  pregnancy
• A-women presenting with persistent vaginal bleeding
  following evacuation of a complete molar pregnancy
  should undergo further uterine evacuation

B- women should be advised not to become pregnant
  until HCG levels have reverted to normal for 6/12 M

  C-mifepristone is recommended for termination of a
  partial molar pregnancy at 14wks gestation
• ANS B                 med-ed-online
Thank you

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MCQ on bleenig in early pregnasncy for undergraduate

  • 1. MCQ on bleeding in early pregnancy DR Manal Behery Zagazig University 2013 med-ed-online
  • 2. Abortion med-ed-online
  • 3. 1-What is wrong about recurrent abortion? A-HSG is the best method to R/O anatomical etiologies B-HSG is recommended several weeks after operative hysteroscopy C-vaginal ultrasonography and MRI are the best techniques to detect anatomical defects D-Septated uterus is the most common anatomical cause of recurrent abortion Ans:A med-ed-online
  • 4. 2- A 20yo, Rh -ve and unsensitised woman has missed miscarriage of 10wks all are true except A- Anti-D immunoglobulin should be administered if surgical evacuation is performed B-Anti-D immunoglobulin is unnecessary after medical evacuation C- products of conception should be sent for histological examination to exclude molar tissue Ans:B med-ed-online
  • 5. Recurrent abortion tests • Karyotype • HSG • Luteal phase biopsy of endometrium • TSH and prolactin level • ACL antibodies • LAC (lupus anticoagulant) • CBC med-ed-online
  • 6. Forcases of abortion without For cases of abortion without fever: fever: Doxy 100 mg bid Doxy 100 mg bid or or tetracycline 250 mg qid tetracycline 250 mg qid for 5-7 days for 5-7 days med-ed-online
  • 7. 3-What is wrong about postabortal or “redo” syndrome? A- It is a complication of suction curettage B- It is a painful cramp in the first 2 hours after curettage C-uterine bleeding is less than expected D-treatment is D&C under anesthesia Ans:D med-ed-online
  • 8. 4- During a sharp curettage of an incomplete abortion uterine is perforated. What is the first step of management? A- curettage should be completed and patient should remain under observation B-laparatomy C-curettage should be stopped and patient should remain under observation D- if there is no hemorrhage in the first 24 hours after operation, the patient can be discharged Ans:B med-ed-online
  • 9. 5-The clinical findings of a woman with GA=8 wks with the chief complaint of hemorrhage and clot passing is an open int os Uterine size about 8 wks and no bleeding. What should be done ? A-No treatment is needed because abortion is complete B-it is a case of threatened abortion C-it is an inevitable abortion D-Abdominal sonography Ans:D med-ed-online
  • 10. 6- A woman has undergone elective abortion one week ago. Now she comes to the clinic with the chief complaint of hemorrhage. In PE cervix is closed, uterine is contracted with no tenderness. Her temperature is normal . What is the best treatment? A-Doxy 100 mg bid for two weeks B-clinda +genta C-observation and check of Hb and Hct D-hormone therapy Ans:D med-ed-online
  • 11. 7- What is the most likely cause of abortion in a 27 year old woman with the past history of two abortions in 10 wks and one in 15 wks with normal Karyotype conceptus? A- endocrine B-immunological C-anatomic D-infectious Ans:B The treatment of immunological recurrent abortion is low dose Heparin sc 5000 units bid+Aspirin 80 mg daily med-ed-online
  • 12. 8-What should be done for a woman 22 years old who has undergone suction curettage and now suffers severe pelvic cramps , sweating and tachycardia. Her uterus is large and tender. She also has spotting. A-observation and oxytocin B-laparatomy CDilation and suction curettage without anesthesia D- CT scan Ans:C med-ed-online
  • 13. 9-What is the best way of pregnancy termination in a bicornuate uterus with a 14 w fetal death? A-dilatation and curettage under US B-uterotonic drugs C-dilatation and curettage under laparascopy D-hysterotomy Ans:B med-ed-online
  • 15. 10-Where is the discriminatory zone? A-3000 IU/L HCG + abdominal US B-1000-1500 IU/L HCG + vaginal US C-a constant value of HCG for any type of US D-in multiple pregnancy it is lower than singleton pregnancy Ans:B med-ed-online
  • 16. Beta HCG below 2000+ no visible intrauterine sac+ mass in tube below 3.5 cm ______________________ Repeat of beta HCG q 48 h A-If a dead IP is confirmed (beta HCG increase less than 50% or below 1000mIu/mL- P below 5 ng/mL + visible intrauterine sac) then curettage B-If EP is confirmed (beta HCG more than 2000 and mass >3.5 cm) then laparascopy C-If a dead IP and EP is confirmed (beta HCG more than 2000 and mass < 3.5 cm) then MTX FETUS SHOULD BE VISIBLE ON DAY 45 OF med-ed-online GESTATION
  • 17. Indication of MTX for EP • Hemodynamic stability • No intra uterine pregnancy • Max sac diameter not equal or more than 4 cm med-ed-online
  • 18. 11-What is your management of a 36 year old woman who is pregnant after primary infertity. She is referring to you for spotting and hypogastric pain, beta HCG is 1500 mu/l and ultrasound of uterus and ovaries are normal. A-laparatomy B-laparascopy C-repeat of vaginal sonography several days later D-progesterone measurement Ans:C med-ed-online
  • 19. 12-A 30 year old woman has become pregnant after 5 years of infertility with ovulation induction and a history of EP in the right tube 2 years ago. She has undergone laparatomy for ruptured right fallopian tube. What is the best technique for this surgery? A-Milking B-linear salpingectomy C-right tube salpingectomy D-segmantal excision and delayed anastomosis Ans:C med-ed-online
  • 20. 13- In a woman 31 years old who has undergone salpingectomy two weeks ago for EP, HCG level is increasing. What is your management? A-MTX B-transvaginal sonography C-salpingectomy D-chest x-ray Ans:B med-ed-online
  • 21. 14-RU486 can not attach to: A-Progesterone receptor B-androgen receptor C-glucocorticosteroid receptor D-estrogen receptor Ans: D med-ed-online
  • 22. 15-What is your management for a woman with : HR=120 BP=80/60 mmHg T=37.5 c uterine size=8 wks beta HCG=2500 mIU/mL and no intrauterine pregnancy in sonography? A-Laparatomy B- laparascopy C- D&C D-serum progesterone Ans:A med-ed-online
  • 23. Adenexal mass< 3.5 cm MTX Adenexal mass=> 3.5 cm -> laparascopy >laparatomy Uncertain US + beta HCG increase less than 50% -> D&C Unstable conditions->laparatomy med-ed-online
  • 24. 16- which is a predisposing factor for ovarian EP? A-PID B-infertility history C-DES exposure D-present IUD Ans:D med-ed-online
  • 25. 17-All are among indications for conservative management of EP except:: A-ovarian EP B-reduced HCG level C-sac of less than 3 cm D-lack of noticeable intra abdominal hemorrhage Ans:A med-ed-online
  • 26. • Gestational trophoblastic disease Vesiculaer mole med-ed-online
  • 27. CASE STUDY • A 21 year old woman comes in for first prenatal visit .Her LMP was 12 wks ago of which she was certain . • Upon examination you noted 20 wks uterus ,therefore an US is performed and revealed bilaterally enlarged adnexa and a snowstorm pattern in the uterus. You suspect a molar pregnancy what is your next step ? med-ed-online
  • 28. You should order B-HCG in serum • The result comes back as 100,000 confirming your suspicion of a complete mole • Of course the definite diagnosis will not be made until a D&C is performed med-ed-online
  • 29. 18-Clinical features that distinguish a complete mole from a partiel mole are A-Gestational age between 8-16 wks B-B HCG level 100,000 C-Uterine size that is larger for gestational age D- Ultrasonographic features E- all of the above Ans:D med-ed-online
  • 30. 19-To optimally prepare for D&C you should take the following steps except A-type and cross match for blood B- full operating room setting C- suction cannula D-General anathesia E- A 22 gauge intravenous access Ans:E med-ed-online
  • 31. 20-With respect to complete mole all are true except • A- Complete moles have 46XX karyotype • B-Maternal serum AFP levels are undetectable in complete moles as there no fetal parts • C-Medical evacuation using prostaglandins and oxytocin is the recommended treatment • D-During surgical evacuation, oxytocin infusion shouldn’t be commenced before the uterus is empty med-ed-online • ANS C
  • 32. 21- All of the following are associated with an increased risk of malignant change in a woman with vesicular molar PPREPREpregnancy except • A-maternal age > 39years HSG • B-woman with BG-A with a partner of BG-O TSH and prolactin level • C-Complete mole more than partial moles • D- smoking • Ans:D med-ed-online
  • 33. Suction evacuation under general anathesia was performed How can you councel this case regarding contraceptive advice before the next pregnancy med-ed-online
  • 34. 22-Which is true regarding contraception after molar evacuation ? A-Women should be advised not to conceive until HCG levels have been normal for 12 mths B-Use of the COCP after HCG levels have returned to normal is associated with increased need for chemotherapy C-Use of IUDs in contraindicated until after HCG levels have returned to normal Ans:C med-ed-online
  • 35. 23-Which is true regarding molar pregnancy • A-women presenting with persistent vaginal bleeding following evacuation of a complete molar pregnancy should undergo further uterine evacuation B- women should be advised not to become pregnant until HCG levels have reverted to normal for 6/12 M C-mifepristone is recommended for termination of a partial molar pregnancy at 14wks gestation • ANS B med-ed-online