2. Clinical Case
• 61 yr gentleman
• February 2012 –
headache, left
hemianopia
• MRI as shown
• Craniotomy for removal
of tumour
• HPE : Glioblastoma
• WBRT and
temozolamide
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4. Clinical Questions:
Does molecular markers in glioblastoma have
dependable diagnostic, prognostic and
treatment guidance value to be considered as
routine investigation?
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5. Search strategy
• P = Patients with glioblastoma
• I = molecular markers
• C=
• O = better prognostic and treatment advice
Search Keywords (exp MESH )
1) “Molecular Markers” “
2) “Glioblastoma”
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