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Local Anesthetics in Dentistry

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Local Anesthetics in Dentistry Bach Van Pham Southern Methodist University November 30, 2004
What are local anesthetics? ,[object Object]
History ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
History (cont.) ,[object Object],[object Object],[object Object],[object Object]
Development of general and local anesthesia ,[object Object],[object Object],[object Object],[object Object]
Development of general and local anesthesia (cont.) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Cocaine Addiction ,[object Object],[object Object],[object Object],[object Object],[object Object]
Side Effects of Cocaine and Solutions ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Procaine replaced Novocaine cocaine Problems ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lidocaine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Differences of Esters and Amides ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Structures of Amides and Esters ,[object Object],[object Object],[object Object]
Mechanism ,[object Object],[object Object],[object Object],[object Object],[object Object]
Factors Affect the Reaction of Local Anesthetics ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Factors Affect the Reaction of Local Anesthetics (cont.) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Toxicity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Factors of circulation levels ,[object Object],[object Object],[object Object],[object Object],[object Object]
Three special drugs used in dental anesthesia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Conclusion 140 - 270 90 - 360 4 hours – 8 hours 120 - 240 45 - 90 Duration (with Epinephrine) in minutes 4.0mg/kg – 7mg/kg Rapid 7.8 Articaine 5mg/kg – 7.5mg/kg Medium 7.9 Prilocaine 2.5mg/kg – 3mg/kg Slow 8.1 Bupivacaine 4.5mg/kg – 7mg/kg Rapid 7.9 Lidocaine 8mg/kg – 10mg/kg Slow 9.1 Procaine Max Dose (with Epinephrine) Onset pKa Anesthetic
References ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

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Local Anesthetics in Dentistry

  • 1. Local Anesthetics in Dentistry Bach Van Pham Southern Methodist University November 30, 2004
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  • 19. Conclusion 140 - 270 90 - 360 4 hours – 8 hours 120 - 240 45 - 90 Duration (with Epinephrine) in minutes 4.0mg/kg – 7mg/kg Rapid 7.8 Articaine 5mg/kg – 7.5mg/kg Medium 7.9 Prilocaine 2.5mg/kg – 3mg/kg Slow 8.1 Bupivacaine 4.5mg/kg – 7mg/kg Rapid 7.9 Lidocaine 8mg/kg – 10mg/kg Slow 9.1 Procaine Max Dose (with Epinephrine) Onset pKa Anesthetic
  • 20.