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What is Brain Injury?
Brain Injury or Behaving Badly?
Stephen Wilson
North Shore Ryde Health Service
Mater Hospital
30 April 2013
Program
• The nerve cell
• Basic Brain Anatomy
• What are the syndromes and behaviours
associated with Brain injury
[TBI/Alcohol/Hypoxia]
The Fragile Nerve Cell
• Oxygen
• Glucose
• Thiamine
• Oxygen
• Glucose
• Thiamine(B1)
• Neuro transmitters
• Protection: Bone, Blood
brain barrier
• Support: CSF, Glial Cells
• Nourishment: Diet
• Growth: Neuroplasticity
Brain Injury
Neurone damage Causes
• Trauma
• From Birth
Intellectual disability
• Infection/Encephalitis
HIV dementia, Tertiary
Syphilis, CJD, Herpes simplex
• Lack of oxygen
Associated with drug
overdose, suicide, cardiac
arrythmia, stroke
• Poisons
Alcohol, Methyl
alcohol, Marijuana
Brain Anatomy
Traumatic Brain Injury
Frontal Syndrome
Structures
Traumatic Brain Injury
Frontal /Executive Function
Behaviour
• Inability making decisions
• Motivation
• Inappropriate behaviour
• Controlling emotions
• Social behaviour
• Lack of Self-awareness
• Neglect appearance
Executive
• Planning and organisation
• Flexible thinking
• Monitoring performance
• Multi-tasking
• Solving unusual problems
• Learning rules
• Concentrating and taking in
information
• Delayed cognitive
processing
Case Study
Alcohol
Structures
Cerebellum
Limbic system
Hippocampus
Peripheral nerves/sensation
Optic nerves (metho)
Alcohol
Korsakoff’s Syndrome
Symptoms
• Poor balance, Ataxia
• Numb feet
• Retrograde Amnesia
• Antero grade amnesia
• Heavy alcohol consumption
• Poor diet and thiamine
deficiency
Behaviour
• Confabulation: invents
events to fill the gaps in
memory
• difficulty in acquiring new
information or learning new
skills
• Poor insight: believe that
their memory is functioning
normally
• Talkative repetitive
Case Study
• Dory: I don't know where I
am... I don't know what's
going on. I think I lost
somebody but I, I can't
remember... and I can't
remember...
• I suffer from short-term
memory loss. It runs in my
family... At least I think it
does... hm. Where *are*
they?
Hypoxia
Structures
• Diffuse brain damage
• Boundary zone/Watershed
• Basal ganglia
Behaviour
• Movement disorders
• Gait Parkinsonism
• Epilepsy
• Cognitive impairment
• Agnosia
• Features of Korsakoff and
TBI
Case Study
Conclusion
• Difficult to decide Psychosis vs Brain damage
• May be co existent
• Understanding the injury may help with
managing behaviour
Questions?

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Assoc. Prof. Stephen Wilson Brain Injury Forumjury

  • 1. What is Brain Injury? Brain Injury or Behaving Badly? Stephen Wilson North Shore Ryde Health Service Mater Hospital 30 April 2013
  • 2. Program • The nerve cell • Basic Brain Anatomy • What are the syndromes and behaviours associated with Brain injury [TBI/Alcohol/Hypoxia]
  • 3. The Fragile Nerve Cell • Oxygen • Glucose • Thiamine • Oxygen • Glucose • Thiamine(B1) • Neuro transmitters • Protection: Bone, Blood brain barrier • Support: CSF, Glial Cells • Nourishment: Diet • Growth: Neuroplasticity
  • 4. Brain Injury Neurone damage Causes • Trauma • From Birth Intellectual disability • Infection/Encephalitis HIV dementia, Tertiary Syphilis, CJD, Herpes simplex • Lack of oxygen Associated with drug overdose, suicide, cardiac arrythmia, stroke • Poisons Alcohol, Methyl alcohol, Marijuana
  • 6. Traumatic Brain Injury Frontal Syndrome Structures
  • 7. Traumatic Brain Injury Frontal /Executive Function Behaviour • Inability making decisions • Motivation • Inappropriate behaviour • Controlling emotions • Social behaviour • Lack of Self-awareness • Neglect appearance Executive • Planning and organisation • Flexible thinking • Monitoring performance • Multi-tasking • Solving unusual problems • Learning rules • Concentrating and taking in information • Delayed cognitive processing
  • 10. Alcohol Korsakoff’s Syndrome Symptoms • Poor balance, Ataxia • Numb feet • Retrograde Amnesia • Antero grade amnesia • Heavy alcohol consumption • Poor diet and thiamine deficiency Behaviour • Confabulation: invents events to fill the gaps in memory • difficulty in acquiring new information or learning new skills • Poor insight: believe that their memory is functioning normally • Talkative repetitive
  • 11. Case Study • Dory: I don't know where I am... I don't know what's going on. I think I lost somebody but I, I can't remember... and I can't remember... • I suffer from short-term memory loss. It runs in my family... At least I think it does... hm. Where *are* they?
  • 12. Hypoxia Structures • Diffuse brain damage • Boundary zone/Watershed • Basal ganglia Behaviour • Movement disorders • Gait Parkinsonism • Epilepsy • Cognitive impairment • Agnosia • Features of Korsakoff and TBI
  • 14. Conclusion • Difficult to decide Psychosis vs Brain damage • May be co existent • Understanding the injury may help with managing behaviour