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The Cold Chain
How you would store
            these products?
•   Vaccine
•   Tetracycline
•   Penicillin/Streptomycin
•   Eye drops
•   Vitamins
•   Anthelminthics
Potency
                                                   100




                                                   80



                                                   60



                                                   40




                                                   20



                                                    0


                                                          1st    3r d




Improper storage of products (vaccines) leads to
                                                         Q tr   Q tr




loss of potency

Potency - induces a good immune response

Once potency is lost, it cannot be regained.
The Cold Chain

is the system that is used to ensure that
products that need special handling are kept
within the safe temperature range of +2°C
and +8°C.
The Cold Chain
Three key elements

• Personnel: to manage vaccine storage and
  distribution.

• Equipment: to store and transport vaccine

• Procedures: to ensure that vaccines are stored
  and transported at appropriate temperatures.
Key Points
• Maintain efficient cold chain from point of
  manufacture to vaccine use.
• All vaccines are damaged by temperatures > +8°C: a
  lot of heat x short time or small amount of heat x long
  period.
• Loss of potency is permanent and irreversible.
• Failure in one link of cold chain will affect product
  potency. Good handling after that will not restore lost
  potency.
• Repeated cold chain failure has additive effect on
  product potency.
• Physical appearance of damaged vaccine may remain
  unchanged.
Healthy poultry

Healthy people

Healthy communities

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The cold chain

  • 2. How you would store these products? • Vaccine • Tetracycline • Penicillin/Streptomycin • Eye drops • Vitamins • Anthelminthics
  • 3. Potency 100 80 60 40 20 0 1st 3r d Improper storage of products (vaccines) leads to Q tr Q tr loss of potency Potency - induces a good immune response Once potency is lost, it cannot be regained.
  • 4. The Cold Chain is the system that is used to ensure that products that need special handling are kept within the safe temperature range of +2°C and +8°C.
  • 6. Three key elements • Personnel: to manage vaccine storage and distribution. • Equipment: to store and transport vaccine • Procedures: to ensure that vaccines are stored and transported at appropriate temperatures.
  • 7. Key Points • Maintain efficient cold chain from point of manufacture to vaccine use. • All vaccines are damaged by temperatures > +8°C: a lot of heat x short time or small amount of heat x long period. • Loss of potency is permanent and irreversible. • Failure in one link of cold chain will affect product potency. Good handling after that will not restore lost potency. • Repeated cold chain failure has additive effect on product potency. • Physical appearance of damaged vaccine may remain unchanged.