1. Lack of sleep can up risk of
type 2 diabetes
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2. Contd..
Those who sleep less are at a higher risk of
diabetes. Lack of sleep has been found to
elevate levels of free fatty acids in the blood
accompanied by temporary pre-diabetic
conditions in healthy young men.
“We have found connections between
restricted sleep, weight gain and type 2
diabetes,“ said Esra Tasali, assistant
professor of medicine at the University of
Chicago. “Experimental laboratory
studieshelp us unravel the mechanisms that
may be responsible.“
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3. Contd..
The study is the first to examine the impact
of sleep loss on 24-hour fatty acid levels in
the blood. It adds to emerging evidence that
insufficient sleep -a highly prevalent
condition in modern society -may disrupt fat
metabolism and reduce the ability of insulin
to regulate blood sugars.
The researchers found that after three
nights of getting only four hours of sleep,
blood levels of fatty acids remained
elevated from about 4 am to 9 am. As long
as fatty acid levels remained high, the ability
of insulin to regulate blood sugars was
reduced.
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4. Contd..
The researchers recruited 19 healthy male
subjects. These volunteers were monitored
through two scenarios in randomized order.
In one they got a full night's rest. In the
other they spent just 4.5 hours in bed.
Each subject's sleep was carefully
monitored, diet was strictly controlled and
blood samples were collected at 15 or 30
minute intervals for 24 hours. They found
that sleep restriction resulted in a 15 to 30%
increase in late night and early morning
fatty acid levels.
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