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A new procedure for noninvasive detection of breast cancer lymph node metastasis
Using two cell surface markers found to be highly expressed in breast cancer lymph node
metastases, our team, which included colleagues at University of Florida and Arizona,
developed targeted, fluorescent molecular imaging probes that can non-invasively detect
breast cancer lymph node metastases. The new procedure could spare breast cancer patients
invasive and unreliable sentinel lymph node biopsies and surgery-associated negative side
effects.
Bibliographic Reference:
Tafreshi NK et al.: "Noninvasive Detection of Breast Cancer Lymph Node Metastasis Using
Carbonic Anhydrases IX and XII Targeted Imaging Probes", Clin Cancer Res. 2012 Jan 1;18
(1):207-19
Narges Tafreshi
Department of Molecular and Functional Imaging, H. Lee Moffitt Cancer Center & Research
Institute, Tampa, FL, USA
http://www.senology.org/Edit_Tafreshi.htm 02/03/2012