Diabetes Insipidus

Diabetes Insipidus Dr Thomas Fox Endocrine SpR RCH

[object Object],[object Object],[object Object]

Outline ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Anti-diuretic hormone (Arginine Vasopressin ) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Water homeostasis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Role of ADH ,[object Object],[object Object],[object Object],[object Object],[object Object]

H20 H20 Collecting Duct Principal cell ADH DNA AQP 2 Synthesis Transport AQP 2 ADH affect on kidney V2 R

ADH production ,[object Object],[object Object],[object Object],[object Object]

ADH Production in response to volume and osmolality changes

ADH Production ,[object Object],[object Object],[object Object],[object Object]

Case 1 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Case cont ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

2 years later ,[object Object],[object Object],[object Object],[object Object],[object Object]

On admission ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object]

Treatment - medical ,[object Object],[object Object],[object Object],[object Object],[object Object]

Treatment – surgical ,[object Object],[object Object],[object Object]

Case 2 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Further investigations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Ophthalmology review ,[object Object]

Pituitary MRI ,[object Object],[object Object],[object Object],[object Object]

Management ,[object Object],[object Object],[object Object],[object Object],[object Object]

Progress ,[object Object],[object Object],[object Object],[object Object]

Differential diagnosis of polydipsia/polyuria ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Causes of cranial DI ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Investigations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Water deprivation test ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Treatment ,[object Object],[object Object],[object Object],[object Object],[object Object]

Conclusions ,[object Object],[object Object],[object Object],[object Object]

Diabetes Insipidus

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Diabetes Insipidus