SlideShare una empresa de Scribd logo
1 de 35
years old 2.5
BSAB 21%
Involving back, upper
buttock rt-arm both loin
, area
Scald injury hot milk
& All vital signs
investigations done with ideal
results
She is doing very well with this large
healthy burnd wound
Slow
healing
but
looks
healthy
Pt doing
good
SYSTEMIC SKIN ERRUPTION
ARE SET TO START
EPIDERMALEXFOLATION
OF EAR SKIN & CHEEKS

SCALP LESION
CRUSTATION+
Human GVHD occur after allogenic 
,stem cell transplantation
Acute GVHD describes a distinctive 
syndrome of Dermatitis,Hepatits,&
Enteritis developing within 100 days
of allogenic hematopoietic cell
transplantation
Chronic GVHD describes a more 
diverse syndrome developing after
day 100
EXCISION – RE
AUTO GRAFTING
Who agree with



Who agree with SYSTIMIC STEROID
TREATMENT IF STARTED Auto -SKIN
GRAFTING ARE CONTRAINDICATED


Take biopsy from lesion & from unburned skin a
.maccule 2 cm distant area from the wound
The allograft are excised ,dressing by sofratule 
mesh gauze and povidon iodin impregnated gauze
. bandaging


DESQUAMATION & BULLAE
Clear face no skin lesion
dramatic response
Before
operation

days later 4
After
operation


Separation of epidermis from dermis (bullae like) (x4)
biopsy 2 cm distant from wound {at un burned skin}


Irregularity in rete ridges

(x4)
Separation of dermis from dermis with upper dermal
inflammation (x10)
)


Upper dermal lymphocytic infiltration (x40) path gnomonic
sign of AGVHD in the Skin
Auto split thickness
Skin-Graft done
2013 5 11

2013 6 18

Thank you
Dr.qutaiba abdulah aldori
Azadi Hospital kerkuk Iraq

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Acute graft versus host disease by dr. qutaiba abdulah