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Cell organisation
Living processes in unicellular
organisms
• Unicellular organisms (organisms which consist a
single cell).
• They are structurally simple, but able to perform
all vital functions and living processes within a
cell.
• They can feed, respire, excrete, move, sensitive to
external and internal conditions (respond to
stimuli), able to reproduce and grow.
• they does not have any systems, so the survival
depends largely on their structure and cellular
components.
• Example of unicellular organisms: protozoa
(Amoeba sp and Paramecium sp)
Amoeba sp
Habitat
• live in freshwater lakes, ponds and damp soil
• Most are free living, but some are parasitic.
General characteristics
• Enclosed by a plasma membrane
• Changes its shape constantly as it meets obstacles
and responds to stimuli.
• Ectoplasm (the gel-like outer part of the cytoplasm),
endoplasm (the inner part of the cytoplasm)
• Moves and feeds by using pseudopodia.
Living processes
1. Locomotion
• Moves by cytoplasmic projection (extending
pseudopodia or ‘false feet’ and anchoring the
tips to the ground)
• Followed by the flow of cytoplasm into the
pseudopodia.
• This form of locomotion is known as ameboid
movement.
2. Feeding
• Feed on microscopic organisms such as bacteria
and diatoms.
• Engulfs food by phagocytosis.
• Nutrition in Amoeba sp:
a) Amoeba sp approaches the food particles.
b) Two pseudopodia extend out and enclose the
food particles.
c) The food particles are packaged in a food
vacuole, which fuses with a lysosome
containing hydrolytic enzymes called lysozyme.
(d) The food particles are digested by the lysozyme.
The resulting nutrients diffuse into the cytoplasm
and are assimilated.
(e) Undigested material is left behind when the
Amoeba sp moves away.
3. Respiration
• Exchange of oxygen and carbon dioxide occurs
through the plasma membrane by diffusion.
4. Excretion
• Waste products such as carbon dioxide and
ammonia are eliminated by diffusion.
• The contractile vacuole is involved in
osmoregulation.
• As Amoeba sp lives in freshwater environments ,
water diffuses into the cell and fills the contractile
vacuole.
• When the vacuole is filled to its maximum size, it
contracts to expel its contents from time to time.
5. Responses to stimuli
• reacts by retreating from adverse stimuli such as
bright light and acidic solutions.
• Favorable stimuli such as contact with
food, cause it to move toward the stimuli.
6. Reproduction
• Reproduces asexually by binary fission and by
forming spores.
• When food is abundant, Amoeba sp reproduces
by binary fission.
• When food is scarce and the condition is
dry, Amoeba sp forms spores.
Binary fission in Amoeba sp
• Amoeba sp divides after it has grown to a certain
size.
• The pseudopodia are pulled in and the nucleus
divides.
• The cytoplasm begin to divide when the nucleus
has split.
• Two daughter amoebae are formed.
7. Growth
• Grow by synthesizing new cytoplasm.
Paramecium sp
Habitat
• Found abundantly in freshwater ponds rich in
decaying organic matter.
General characteristics
• The surface is covered by numerous rows of cilia
(short hair-like outgrowths which cover the entire
outer surface of the Paramecium sp).
• cilia are involved in locomotion and feeding.
Living processes
1. Locomotion
• Moves by means of the rhythmic beating of the
cilia.
• This action enable the Paramecium sp to move
forward while rotating and spiralling along its
axis.
2. Feeding
• Feed on microscopic organisms.
• Nutrition in Paramecium sp:
a) the rhythmic beating of cilia along a mouth-like
opening (oral groove) sweeps water and
suspended food particles into the cytostome.
b) In the cytostome, food vacuoles containing the
food particles are formed.
c) The food particles in the food vacuoles are
digested by hydrolytic enzymes from the
cytoplasm.
d) Nutrients from the digested food then dissolve
and diffuse into the cytoplasm and are used to
generate energy.
e) The undigested contents are released through
the anal pore.
3. Respiration
• Gaseous exchange occurs by diffusion through
the entire plasma membrane.
4. Excretion
• Waste products are expelled from the cell by
diffusion.
• Control of water balance in the cell
(osmoregulation) is aided by two contractile
vacuoles (one at the anterior and the other at
the posterior end).
• This is necessary because Paramecium sp
constantly takes in water from the hypotonic
environment by osmosis.
• Contractile vacuoles periodically expand, filling
with water, and then contract to expel their
contents to the exterior of the cell.
5. Responses to stimuli
• Has cilia which function as sensory structures.
• It is sensitive to chemicals, oxygen, carbon
dioxide, pH and physical stimuli such as light,
contact and temperature.
• Moves in the opposite direction when it comes
into contact with adverse stimuli.
6. Reproduction
• Reproduce asexually as well as sexually.
• Has two nuclei. macronucleus control cellular
metabolism of the cell and for asexual
reproduction (binary fission, occur in favorable
environment). micronucleus is required for
sexual reproduction (conjugation, occur in
unfavorable environment).
• Binary fission in Paramecium sp:
 Macronucleus and micronucleus divide.
 The cytoplasm divides when the nuclei have
split.
 Two daughter Paramecium sp are formed.
7. Growth
• Grow to a certain size by synthesizing new
cytoplasm.
Cell specialisation in multicellular
organisms
• Multicellular organisms (organisms that consist
more than one cell).
• Cell specialisation (a process of change and
adaptation that a cell undergoes to give it special
structures and specific functions).
• Human and other multicellular organisms begin
life as a single cell known as a zygote (result of
fertilisation between an ovum and a sperm.
• Then, zygote divides into two identical cells
divide to become four cells, and so on until it
forms a ball of cells (embryo).
• These cells grow, change shape and adapt
themselves to carry out specific functions.
• They differentiate and become specialised in
order to perform specific tasks more efficiently.
• The different levels of cell organisation as below:
A group of cells (similar in structure, perform a
specialised function) tissue.
Different types of tissues organs.
Several organs system.
All systems multicellular organism.
• Without cell specialisation, organism will not be
able to survive itself, given the complexity and
the millions of cells found in its body.
• Organisation into cells, tissues, organs and
systems is essential to multicellular organisms
because:
a group of cells or tissues are able to carry out a
specific function more efficiently compared to a
single cell.
the division of labour among cells enables the
organisms to carry out the various tasks and
functions in an orderly and systematic manner.
this enables them to achieve a higher growth
rate.
organism are able to adapt and survive in diverse
habitats and environments.
all living processes can be carried out more
efficiently.
A few types of human cells
1. Nerve cells
• Have long, thin fibres called axons which
conduct nerve impulses throughout the body.
2. Muscle cells
• Are usually long with multiple nuclei and
contain protein fibres. These fibres can contract
to produce movement.
3. Red blood cells
• Are shaped like a biconcave disc and lack a
nucleus. This increase their efficiency in
transporting oxygen.
4. White blood cells
• Can change their shape easily to move through
the walls of blood vessels and migrate to the sites
of injuries.
5. Sperm cells
• Have long tails and a high density of
mitochondria which allow them to swim
towards the ovum.
• The nucleus contains one set of chromosomes
from the male parent.
6. Epithelial cells with simple glands
• Found in the intestines.
• Function: secrete mucus
• The epithelial layer is highly folded with the
secretory cells arranged compactly to increase
the surface area for mucus secretion.
tissues
• Four major types of tissues in animals:
1. Epithelial tissues
 Consist of one or more layers of cells.
 The cells of an epithelium are tightly
interconnected, with little space between them.
 They form a continuous layer over body surfaces
(skin and mouth area), inner lining of cavities
(digestive tract and lungs), and also form glands
(exocrine and endocrine glands).
Functions:
a) Epithelial cells carry out functions associated
with protection, secretion and absorption.
b) At surface of the skin, act as a protective barrier
against infections, mechanical injuries,
chemicals, dehydration and regulate body
temperature.
c) The epithelial cells (alveoli of the lungs and the
walls of blood capillaries) are thin, flattened and
arranged in a single layer (allow the exchange of
gases between the alveoli and the blood in the
capillaries to take place efficiently).
d) In the lining of the small intestine, absorb
nutrients after digestion is completed.
e) Undergo modification to form mucus-secreting
goblet cells which secrete mucus into the
digestive tract.
f) Certain epithelial tissues are modified to form
glands in the skin (sweat glands and
sebaceous/oil-secreting glands).
g) The epithelial tissues that lines the trachea
consist of elongated cells with hair-like
projections called cilia. They secrete mucus (trap
dust particles while the cilia sweep the impurities
away from the lungs).
2. Muscle tissues
The most abundant tissues in most animals.
Composed of long cells called muscle fibres.
Three types of muscle tissues:
a) Smooth muscles (along the walls of the
digestive tract, blood vessels, bladder and
reproductive tract).
b) Skeletal muscles (attached to the bones of the
skeletal).
c) Cardiac muscles (form the contractile wall of the
heart).
Function:
a) Smooth muscles
• responsible for the involuntary actions of the
body. Example: when the smooth muscles of
the intestine contract, food is moved along the
digestive tract.
• Responsible for the churning action of the
stomach and the constriction of arteries.
• Contract more slowly than skeletal muscles but
remain contracted for a longer period of time.
b) Skeletal muscles
• Responsible for the voluntary movements of the
body. Contractions of skeletal muscles produce
movements of various body parts.
c) Cardiac muscles
• Contract to pump blood to all parts of the body.
Contractions are involuntary.
3. Nerve tissues
Composed of neurones, or nerve cells.
Each neurone consists of a cell body and nerve
fibres called dendrites and axons.
Three types of neurones:
a) Afferent neurones
b) Efferent neurones
c) Interneurones
Function:
a) Neurones are specialised to transmit signals
called nerve impulses over long distances.
b) Nerve tissues control and coordinate all
activities of the body.
4. Connective tissues
Consist of various types of cells and fibres
separated by an extracellular matrix.
The connective tissues which underlines
epithelial tissues consists of a network of
collagen, capillaries and spaces filled with fluid.
Examples: tendons, ligaments, cartilage, bones,
blood, lymph and adipose tissue.
Connective tissues, with the exception of blood
and lymph, are interwoven with fibrous strands
called collagen.
tendons and ligaments: formed when the
collagen fibres are densely packed.
cartilage: strong yet flexible connective tissues.
Bones: consist of cells embedded in a matrix of
collagen hardened by mineral deposits such as
calcium. This combination makes the bones
harder than cartilage.
Blood: consists of red and white blood cells and
cell fragments called platelets, suspended in a
fluid called blood plasma. Blood cells are
manufactured in the bone marrow, located at the
ends of long bones.
Lymph: consists mostly of fluid which leaks out of
blood capillaries.
Adipose tissues (formed by fat cells): tightly
packed. Found in the dermis of the skin.
Functions:
a) Bind structures together, provide support and
protection to other tissues.
b) Tendon: attach muscles to bones.
c) Ligaments: attach bones to bones.
d) Cartilage: provides support to nose, ears, and
the ends of bones at joints. Also forms discs
between the vertebrae. This enables them to act
as cushions to absorb pressure.
e) Bones: provide protection to organs in the body
and supports the body.
f) blood: has regulating, transporting and
protective functions. transports nutrients and
oxygen to cells and removes carbon dioxide and
waste products from the cells. Distribute heat
throughout the body and contains regulatory
substances (hormones and enzymes). Red blood
cells transport oxygen, white blood cells assist in
fighting infections, platelets aid in blood clotting.
g) Adipose tissues: store energy and insulate the
body.
Organs
• Formed by two or more types of tissues (not
individual tissues) working together to perform
particular functions.
• Examples: heart, skin, lungs, kidneys, eyes and
ears.
• The heart consists of cardiac muscle, connective
tissue, nerve tissue and epithelial tissues. These
tissues work together to pump blood to all parts
of the body.
Skin
• Covers the entire body, and acts as a barrier
against in infection, physical trauma and water
loss.
• The largest organ of the body.
• Is organ because it consists of various types of
tissues combined together to perform specific
functions.
• Divided into two main layers (epidermis and
dermis).
• Epidermis: the outermost, thinner layer of the
skin. Mostly made up of dead epithelial cells
which continually slough off.
epithelial cells at the basal layer of the
epidermis undergo continuous cell division.
• Dermis: composed of connective tissue, nerve
tissue, epithelial tissue and muscle tissue.
Connective tissue contain elastic fibres and
collagen fibres. Elastic fibres give elasticity to the
skin, allow the skin to return to its original shape
after being stretched.
Various nerve endings are scattered all over the
dermis and epidermis. These nerve endings are
receptors for pressure, temperature, touch and
pain. They detect various stimuli and transmit
nerve impulses to the nervous system.
Epithelial cells: form glands such as hair follicles
(produce hair), sweat glands (secrete sweat), oil
glands (secrete sebum). Sebum is an oily
substance that lubricates the hair and the skin.
Smooth muscle (hair erector muscle) is attached
to the hair follicle. when contracted, it causes the
hair to stand on end.
systems
• Each system consists of several organs that
cooperate to carry out a living process (digestion
of food).
• 11 major systems in humans:
1. Nervous system
 Major organs: brain, spinal cord, nerves
Main functions: detects stimuli, formulates
responses, transmits nerve impulses and
integrates the activities of systems. Controls
physiological processes in conjunction with the
endocrine system.
2. Skeletal system
Major organs: bones, cartilage, tendons,
ligaments
Major functions: supports the body, provides
sites for attachment of muscles, and protection
for internal organs.
3. Circulatory system
Major organs: heart, blood vessels, blood
Main functions: delivers nutrients, respiratory
gases and hormones to body cells. Transports
waste products to excretory organs.
4. Digestive system
Major organs: mouth, pharynx, esophagus,
stomach, liver, pancreas, small and large
intestines, anus.
Main functions: ingests and digests food,
absorbs nutrients for use by the body and
eliminates undigested material.
5. Respiratory system
Major organs: nose, trachea, lungs
Main functions: provides a surface area for gases
exchange between the blood and the external
environment. Allows oxygen intake and carbon
dioxide elimination.
6. Excretory system
Major organs: kidneys, ureters, urinary bladder,
urethra, skin, lungs.
Main functions: removes metabolic waste
products (urea and carbon dioxide). Regulates
the osmotic balance of the blood.
7. Reproductive system
Major organs: male (testes, seminal vesicles,
penis), female (ovaries, Fallopian tubes, uterus,
cervix, vagina)
Main functions: male (produces sperms and male
hormones), female (produces ova, nurtures
developing foetuses, and produces female
hormones.
8. Muscular system
Major organs: skeletal muscles, smooth muscles
and cardiac muscles
Main functions: contraction of muscles enables
body movements.
9. Integumentary system
Major organs: skin
Main functions: physically separates the body
from the external environment. Protects the
body against mechanical injuries, microbial
infection and dehydration.
10. Endocrine system
Major organs: glands (pituitary, thyroid, adrenal
and pancreas) secrete hormones.
Main functions: coordinates body activities in
conjunction with the nervous system.
11. Lymphatic system
Major organs: lymph vessels, lymph nodes, bone
marrow, thymus.
Main functions: defends the body against
infections. Returns tissues fluid to the blood.
• An organ may belong to more than one system.
Example: pancreas secretes hormones and
pancreatic juice. Pancreas is a part of the
endocrine system and the digestive system.
• All systems combine to form a multicellular
organism.
Cell organisation in plants
• Plant cells also undergo cell specialisation.
• plant cells undergo differentiation and become
specialised in structure and function:
1. Mesophyll palisade cells
 Consist of elongated, cylindrical cells, arranged
vertically and close to one another, situated just
below the upper epidermis. This allow as much
light as possible to reach the chloroplasts for
photosynthesis.
Contain a large number of chloroplasts for
maximum absorption of sunlight.
2. Xylem vessels
No cytoplasm, hence, water can pass freely.
The end walls of the cells are perforated, and the
cells form a continuous vessel or tube which
allows water and mineral salts to be transported
in the plant.
3. Guard cells
Specialised epidermal cells at the lower
epidermis which are kidney-shaped when turgid.
Control the size of the stoma by changing their
shape.
4. Root hairs
Have a long extension which increases the
surface area for absorption of minerals and water
from the soil.
• 2 main types of tissues (meristematic tissues and
permanent tissues) form plant organs (leaves,
stems and roots).
1. Meristematic tissues
Consists of small cells which have thin walls,
large nuclei, dense cytoplasm and no vacuoles.
Comprise young and actively dividing cells which
have not undergone differentiation.
Apical meristems are located at the tips of roots
and the buds of shoots. The tissues undergo
mitotic cell division to increase the number of
cells for plant growth.
Lateral meristems/cambia are found in the
peripheral areas of stems and roots. They are
responsible for secondary growth which adds
girth to the plants.
2. Permanent tissues
Consist of more mature cells that are either
undergoing differentiation or have already
undergone differentiation.
3 types of permanent tissues:
a) Epidermal tissue
 Characteristics
i. Forms the epidermis (the outermost layer that
covers the stems, leaves and roots of young
plants). This tissues also covers the flowers,
fruits and seeds.
ii. The walls of epidermal cells which are exposed
to air are normally covered by a waxy,
waterproof coating called the cuticle.
iii. Most are flat and have large vacuoles.
 Functions
i. The cuticle helps prevent the loss of excessive
water through evaporation, protects the plant
from mechanical injury and prevents invasion
by disease-causing microorganisms.
ii. In roots, some have long projections called root
hairs. These specialised structures increase the
surface area for absorption of water and
minerals.
iii. In leaves, the lower epidermis contains
specialised cells (guard cells) which surround the
stomata.
b) Ground tissue
Forms the bulk of a plant.
3 types of ground tissues:
1) Parenchyma tissue
 Characteristics
i. Consists of thin-walled cells which are loosely
arranged with spaces between them.
ii. cells have a large vacuole.
iii. The least specialised cells and can be found in
all the organs of a plant.
 Functions
i. Parenchyma cells store products of
photosynthesis (sugar and starch).
ii. The palisade mesophyll cells and spongy
mesophyll cells in leaves are specialised
parenchyma cells which contain chloroplasts
and carry out photosynthesis.
iii. Gives support and shape to plants.
2) Collenchyma tissue
 Characteristics
i. Consists of elongated, polygonal cells with
unevenly thickened cell walls (thickened by
cellulose and pectin. Strong and flexible).
 Functions
i. an important source of support in herbaceous
plants, young stems, leaf stalks and petioles.
3) Sclerenchyma tissue
 Characteristics
i. Sclerenchyma cells are much more rigid than
collenchyma cells because they have cell walls
which are uniformly thickened by lignin.
ii. Most of the cells are dead at maturity.
 Functions
i. Supports and strengthens the plant body and
provides protection to the plant.
c) Vascular tissue
Vascular tissues (are continuous throughout the
plant) are involved in the transport of substances
between the roots and shoots.
2 types of vascular tissues:
1) Xylem tissue
 characteristics
i. Xylem consists of tracheids and xylem vessels.
these are long tubes joined together end to
end, stretching from the roots right up to the
shoots.
ii. The cell walls of the xylem are thickened with
lignin which prevents food substances from
entering the cells.
iii. Dies upon reaching maturity.
iv. When the cytoplasm disintegrates, a hollow tube
is left behind. This allows water and minerals to
flow easily through the xylem vessels.
 Functions
i. Xylem conducts water and minerals from the
roots to the leaves.
ii. It provides support and mechanical strength to
the plant.
2) Phloem tissue
 Characteristics
i. Consists of parenchyma cells, sclereids, sieve
tubes and companion cells.
ii. The conducting cells of phloem are the sieve
tubes (have pores at both ends, called sieve
plates. Obtain nutrients and energy from the
adjacent companion cells).
 Functions
i. Phloem transports organic nutrients
(carbohydrates and amino acids) downwards
from the leaves to storage organs and growing
parts of plants.
Organs and systems in plants
• Plant organs: leaves, stems, roots and flowers.
• Systems in plants are not specialised as those of
animals. Plants have fewer organs as compared
to animals.
• Flowering plants (angiosperms) consist of 2 main
systems:
1. Root system
 Is the absorptive system of a plant.
The roots are highly branched to absorb water
and minerals from the soil and transport them to
the main vascular system (xylem).
 the roots anchor the plant to the ground.
2. Shoot system
Consists of organs (stems, leaves, buds, flowers
and fruits).
Stems and branches act as a support system for
the plant by holding the leaves in a position that
facilitate maximum absorption of sunlight during
photosynthesis. They also position the flowers
for pollination.
Leaves are made of ground tissue, epidermal
tissue, mesophyll tissue and vascular tissue.
They form the main photosynthetic system
(synthesises organic compounds required for
plant growth).
The products of photosynthesis are transported
via the vascular system (phloem) to other parts of
plants.
Reproductive system of plants consists of flowers
which produce fruits after fertilisation has taken
place.
The internal environment of
multicellular organisms
• Although multicellular organism lives in external
environment, the cells of its body live within
internal environment (consists of the interstitial
fluid and blood plasma).
• interstitial fluid fills the spaces between the cells
and constantly bathes the cells.
• Nutrients and waste substances are exchanged
between the interstitial fluid and the blood
plasma (contained in the blood capillaries).
The necessity for maintaining optimal
internal environment
• In order for cells of the body to function
optimally, the physical factors and the chemical
composition within the internal environment
must be maintained at relatively constant level
regardless of the conditions outside the cells.
• Physical factors: temperature, blood pressure,
osmotic.
• Chemical factors: salt and sugar contents, pH.
• Homeostasis is the maintenance of a relatively
constant internal environment for the optimal
functions of cells.
• In humans and animals, mechanism of
homeostasis maintain the physical factors and
chemical factors of the internal environment at
steady state with minimal fluctuations.
In homeostatic control mechanism, the change in
internal environment
detected
receptor
send message
control centre
processes information
effector
(bring about a counter response that reverse the
change back to original condition)
• in plants, the need for regulatory system is lesser
because:
a) Most plant cells are dead at functional maturity,
so chemical reactions do not take place in these
cells.
b) Plant cells are not bathed in fluid but surrounded
by air.
c) Plant cells do not lyse in hypotonic environment
because they have cell walls.
d) Water movement in plants is aided by natural
factors (transpirational pull).
The importance of regulating optimal
internal environment
• Ensure optimal cellular activities at times when
the external environment (temperature of
environment) changes.
• Enable organisms to live in a wider range of
habitats.
• Metabolic activities and physiological processes
can still continue even though the external
environment fluctuates substantially.
• Organisms can control the metabolic rate
according to their needs because any internal
fluctuations can be corrected through the
homeostatic control system.
• Ensure a more efficient and optimal metabolism
in the cell.
• A stable internal environment allows enzymes to
function at optimal rate.
The involvement of various system in
maintaining optimal internal
environment
• Physical factors/chemical factors of the internal
environment:
1. Body temperature
 Systems involved
 Integumentary system (skin and sweat glands).
 Nervous system
 Circulatory system
 Muscular system
 Endocrine system
 Types of regulation
Regulate the balance of heat loss and heat gain
to maintain stable body temperature of 37oC.
When the temperature of the body rises above
the normal value,
Thermoreceptors in the skin detect the change in
temperature.
The nervous system conveys the information to
the hypothalamus.
Then, the information is conveyed to effectors.
The effectors involved are:
a) Sweat glands: secrete more sweat to cool the
body through evaporation.
b) Blood vessels: dilate to increase heat loss to the
environment.
c) Hair erector muscles: relax so as to flatten hair
to reduce insulation.
d) Thyroid gland: less stimulated, the secretion of
thyroxine is reduced and this result in a lower
basal metabolic rate.
Overall result: lowering of the body temperature
to the normal level.
On cold day, the opposite mechanism occur.
2. Oxygen and carbon dioxide levels
 Systems involved
Respiratory system
Circulatory system
Nervous system
 Types of regulation
Regulate the concentration of oxygen and
carbon dioxide in the bloodstream.
circulatory system transports oxygen from the
lung to the cells. Carbon dioxide produced
during respiration diffuse into the bloodstream
and is transported back to the lungs.
The change in the concentration of oxygen and
carbon dioxide are detected by the nervous
system.
3. Blood glucose level
 Systems involved
Endocrine system (pancreas)
Circulatory system
Digestive system (liver)
 Types of regulation
Regulate blood glucose level at a set point of 90
mg per 100 cm3.
Pancreas secrete insulin when the level of
glucose in the blood rises above the set point.
Circulatory system transport insulin to the liver.
Insulin stimulate liver cells to convert glucose
into glycogen. Blood glucose level drops.
When the glucose level falls below the set point,
pancreas secrete glucagon (promote the
breakdown of glycogen and the release of
glucose into the blood).
4. Blood osmotic pressure
 Systems involved
Nervous system
Endocrine system
Excretory system
Circulatory system
 Types of regulation
Regulate the amount of water and dissolved
substances (mineral salts) in the tissue fluid and
blood.
5. pH
 Systems involved
Respiratory system
Circulatory system
Excretory system (kidneys)
 Types of regulation
pH of blood and tissue fluid is maintained at a
value of 7.4 by regulating the concentration of
hydrogen ions (H+), hydroxyl ions (OH-) and
hydrogen carbonate ions (HCO3
-).
Appreciating the uniqueness of the
cell
• Cell: the basic unit of all living organisms and is
capable of functioning on its own.
• Cellular components of the cell are completely
dependent upon one another for the cell to
function at optimal level.
• The cell as a whole will not be able to function
properly if any of its cellular components loses its
ability to function normally. Optimal cellular
function is the result of cellular order within the
cell.
• Systems of organisms are able to function
efficiently because the cellular components of
cells work together and cooperate harmoniously
with each other.
• This ensure the survival of the organism.

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Cell Organisation

  • 2. Living processes in unicellular organisms • Unicellular organisms (organisms which consist a single cell). • They are structurally simple, but able to perform all vital functions and living processes within a cell. • They can feed, respire, excrete, move, sensitive to external and internal conditions (respond to stimuli), able to reproduce and grow.
  • 3. • they does not have any systems, so the survival depends largely on their structure and cellular components. • Example of unicellular organisms: protozoa (Amoeba sp and Paramecium sp)
  • 4. Amoeba sp Habitat • live in freshwater lakes, ponds and damp soil • Most are free living, but some are parasitic. General characteristics • Enclosed by a plasma membrane • Changes its shape constantly as it meets obstacles and responds to stimuli. • Ectoplasm (the gel-like outer part of the cytoplasm), endoplasm (the inner part of the cytoplasm) • Moves and feeds by using pseudopodia.
  • 5. Living processes 1. Locomotion • Moves by cytoplasmic projection (extending pseudopodia or ‘false feet’ and anchoring the tips to the ground) • Followed by the flow of cytoplasm into the pseudopodia. • This form of locomotion is known as ameboid movement.
  • 6. 2. Feeding • Feed on microscopic organisms such as bacteria and diatoms. • Engulfs food by phagocytosis. • Nutrition in Amoeba sp: a) Amoeba sp approaches the food particles. b) Two pseudopodia extend out and enclose the food particles. c) The food particles are packaged in a food vacuole, which fuses with a lysosome containing hydrolytic enzymes called lysozyme.
  • 7. (d) The food particles are digested by the lysozyme. The resulting nutrients diffuse into the cytoplasm and are assimilated. (e) Undigested material is left behind when the Amoeba sp moves away. 3. Respiration • Exchange of oxygen and carbon dioxide occurs through the plasma membrane by diffusion.
  • 8. 4. Excretion • Waste products such as carbon dioxide and ammonia are eliminated by diffusion. • The contractile vacuole is involved in osmoregulation. • As Amoeba sp lives in freshwater environments , water diffuses into the cell and fills the contractile vacuole. • When the vacuole is filled to its maximum size, it contracts to expel its contents from time to time.
  • 9. 5. Responses to stimuli • reacts by retreating from adverse stimuli such as bright light and acidic solutions. • Favorable stimuli such as contact with food, cause it to move toward the stimuli. 6. Reproduction • Reproduces asexually by binary fission and by forming spores. • When food is abundant, Amoeba sp reproduces by binary fission. • When food is scarce and the condition is dry, Amoeba sp forms spores.
  • 10. Binary fission in Amoeba sp • Amoeba sp divides after it has grown to a certain size. • The pseudopodia are pulled in and the nucleus divides. • The cytoplasm begin to divide when the nucleus has split. • Two daughter amoebae are formed. 7. Growth • Grow by synthesizing new cytoplasm.
  • 11. Paramecium sp Habitat • Found abundantly in freshwater ponds rich in decaying organic matter. General characteristics • The surface is covered by numerous rows of cilia (short hair-like outgrowths which cover the entire outer surface of the Paramecium sp). • cilia are involved in locomotion and feeding.
  • 12. Living processes 1. Locomotion • Moves by means of the rhythmic beating of the cilia. • This action enable the Paramecium sp to move forward while rotating and spiralling along its axis. 2. Feeding • Feed on microscopic organisms.
  • 13. • Nutrition in Paramecium sp: a) the rhythmic beating of cilia along a mouth-like opening (oral groove) sweeps water and suspended food particles into the cytostome. b) In the cytostome, food vacuoles containing the food particles are formed. c) The food particles in the food vacuoles are digested by hydrolytic enzymes from the cytoplasm. d) Nutrients from the digested food then dissolve and diffuse into the cytoplasm and are used to generate energy.
  • 14. e) The undigested contents are released through the anal pore. 3. Respiration • Gaseous exchange occurs by diffusion through the entire plasma membrane.
  • 15. 4. Excretion • Waste products are expelled from the cell by diffusion. • Control of water balance in the cell (osmoregulation) is aided by two contractile vacuoles (one at the anterior and the other at the posterior end). • This is necessary because Paramecium sp constantly takes in water from the hypotonic environment by osmosis. • Contractile vacuoles periodically expand, filling with water, and then contract to expel their contents to the exterior of the cell.
  • 16. 5. Responses to stimuli • Has cilia which function as sensory structures. • It is sensitive to chemicals, oxygen, carbon dioxide, pH and physical stimuli such as light, contact and temperature. • Moves in the opposite direction when it comes into contact with adverse stimuli. 6. Reproduction • Reproduce asexually as well as sexually.
  • 17. • Has two nuclei. macronucleus control cellular metabolism of the cell and for asexual reproduction (binary fission, occur in favorable environment). micronucleus is required for sexual reproduction (conjugation, occur in unfavorable environment). • Binary fission in Paramecium sp:  Macronucleus and micronucleus divide.  The cytoplasm divides when the nuclei have split.  Two daughter Paramecium sp are formed.
  • 18. 7. Growth • Grow to a certain size by synthesizing new cytoplasm.
  • 19. Cell specialisation in multicellular organisms • Multicellular organisms (organisms that consist more than one cell). • Cell specialisation (a process of change and adaptation that a cell undergoes to give it special structures and specific functions). • Human and other multicellular organisms begin life as a single cell known as a zygote (result of fertilisation between an ovum and a sperm.
  • 20. • Then, zygote divides into two identical cells divide to become four cells, and so on until it forms a ball of cells (embryo). • These cells grow, change shape and adapt themselves to carry out specific functions. • They differentiate and become specialised in order to perform specific tasks more efficiently. • The different levels of cell organisation as below: A group of cells (similar in structure, perform a specialised function) tissue. Different types of tissues organs.
  • 21. Several organs system. All systems multicellular organism. • Without cell specialisation, organism will not be able to survive itself, given the complexity and the millions of cells found in its body. • Organisation into cells, tissues, organs and systems is essential to multicellular organisms because: a group of cells or tissues are able to carry out a specific function more efficiently compared to a single cell.
  • 22. the division of labour among cells enables the organisms to carry out the various tasks and functions in an orderly and systematic manner. this enables them to achieve a higher growth rate. organism are able to adapt and survive in diverse habitats and environments. all living processes can be carried out more efficiently.
  • 23. A few types of human cells 1. Nerve cells • Have long, thin fibres called axons which conduct nerve impulses throughout the body. 2. Muscle cells • Are usually long with multiple nuclei and contain protein fibres. These fibres can contract to produce movement.
  • 24. 3. Red blood cells • Are shaped like a biconcave disc and lack a nucleus. This increase their efficiency in transporting oxygen. 4. White blood cells • Can change their shape easily to move through the walls of blood vessels and migrate to the sites of injuries.
  • 25. 5. Sperm cells • Have long tails and a high density of mitochondria which allow them to swim towards the ovum. • The nucleus contains one set of chromosomes from the male parent. 6. Epithelial cells with simple glands • Found in the intestines. • Function: secrete mucus • The epithelial layer is highly folded with the secretory cells arranged compactly to increase the surface area for mucus secretion.
  • 26. tissues • Four major types of tissues in animals: 1. Epithelial tissues  Consist of one or more layers of cells.  The cells of an epithelium are tightly interconnected, with little space between them.  They form a continuous layer over body surfaces (skin and mouth area), inner lining of cavities (digestive tract and lungs), and also form glands (exocrine and endocrine glands).
  • 27. Functions: a) Epithelial cells carry out functions associated with protection, secretion and absorption. b) At surface of the skin, act as a protective barrier against infections, mechanical injuries, chemicals, dehydration and regulate body temperature.
  • 28. c) The epithelial cells (alveoli of the lungs and the walls of blood capillaries) are thin, flattened and arranged in a single layer (allow the exchange of gases between the alveoli and the blood in the capillaries to take place efficiently). d) In the lining of the small intestine, absorb nutrients after digestion is completed. e) Undergo modification to form mucus-secreting goblet cells which secrete mucus into the digestive tract.
  • 29. f) Certain epithelial tissues are modified to form glands in the skin (sweat glands and sebaceous/oil-secreting glands). g) The epithelial tissues that lines the trachea consist of elongated cells with hair-like projections called cilia. They secrete mucus (trap dust particles while the cilia sweep the impurities away from the lungs).
  • 30. 2. Muscle tissues The most abundant tissues in most animals. Composed of long cells called muscle fibres. Three types of muscle tissues: a) Smooth muscles (along the walls of the digestive tract, blood vessels, bladder and reproductive tract). b) Skeletal muscles (attached to the bones of the skeletal). c) Cardiac muscles (form the contractile wall of the heart).
  • 31. Function: a) Smooth muscles • responsible for the involuntary actions of the body. Example: when the smooth muscles of the intestine contract, food is moved along the digestive tract. • Responsible for the churning action of the stomach and the constriction of arteries. • Contract more slowly than skeletal muscles but remain contracted for a longer period of time.
  • 32. b) Skeletal muscles • Responsible for the voluntary movements of the body. Contractions of skeletal muscles produce movements of various body parts. c) Cardiac muscles • Contract to pump blood to all parts of the body. Contractions are involuntary.
  • 33. 3. Nerve tissues Composed of neurones, or nerve cells. Each neurone consists of a cell body and nerve fibres called dendrites and axons. Three types of neurones: a) Afferent neurones b) Efferent neurones c) Interneurones
  • 34. Function: a) Neurones are specialised to transmit signals called nerve impulses over long distances. b) Nerve tissues control and coordinate all activities of the body.
  • 35. 4. Connective tissues Consist of various types of cells and fibres separated by an extracellular matrix. The connective tissues which underlines epithelial tissues consists of a network of collagen, capillaries and spaces filled with fluid. Examples: tendons, ligaments, cartilage, bones, blood, lymph and adipose tissue. Connective tissues, with the exception of blood and lymph, are interwoven with fibrous strands called collagen.
  • 36. tendons and ligaments: formed when the collagen fibres are densely packed. cartilage: strong yet flexible connective tissues. Bones: consist of cells embedded in a matrix of collagen hardened by mineral deposits such as calcium. This combination makes the bones harder than cartilage.
  • 37. Blood: consists of red and white blood cells and cell fragments called platelets, suspended in a fluid called blood plasma. Blood cells are manufactured in the bone marrow, located at the ends of long bones. Lymph: consists mostly of fluid which leaks out of blood capillaries. Adipose tissues (formed by fat cells): tightly packed. Found in the dermis of the skin.
  • 38. Functions: a) Bind structures together, provide support and protection to other tissues. b) Tendon: attach muscles to bones. c) Ligaments: attach bones to bones. d) Cartilage: provides support to nose, ears, and the ends of bones at joints. Also forms discs between the vertebrae. This enables them to act as cushions to absorb pressure. e) Bones: provide protection to organs in the body and supports the body.
  • 39. f) blood: has regulating, transporting and protective functions. transports nutrients and oxygen to cells and removes carbon dioxide and waste products from the cells. Distribute heat throughout the body and contains regulatory substances (hormones and enzymes). Red blood cells transport oxygen, white blood cells assist in fighting infections, platelets aid in blood clotting. g) Adipose tissues: store energy and insulate the body.
  • 40. Organs • Formed by two or more types of tissues (not individual tissues) working together to perform particular functions. • Examples: heart, skin, lungs, kidneys, eyes and ears. • The heart consists of cardiac muscle, connective tissue, nerve tissue and epithelial tissues. These tissues work together to pump blood to all parts of the body.
  • 41. Skin • Covers the entire body, and acts as a barrier against in infection, physical trauma and water loss. • The largest organ of the body. • Is organ because it consists of various types of tissues combined together to perform specific functions. • Divided into two main layers (epidermis and dermis).
  • 42. • Epidermis: the outermost, thinner layer of the skin. Mostly made up of dead epithelial cells which continually slough off. epithelial cells at the basal layer of the epidermis undergo continuous cell division.
  • 43. • Dermis: composed of connective tissue, nerve tissue, epithelial tissue and muscle tissue. Connective tissue contain elastic fibres and collagen fibres. Elastic fibres give elasticity to the skin, allow the skin to return to its original shape after being stretched. Various nerve endings are scattered all over the dermis and epidermis. These nerve endings are receptors for pressure, temperature, touch and pain. They detect various stimuli and transmit nerve impulses to the nervous system.
  • 44. Epithelial cells: form glands such as hair follicles (produce hair), sweat glands (secrete sweat), oil glands (secrete sebum). Sebum is an oily substance that lubricates the hair and the skin. Smooth muscle (hair erector muscle) is attached to the hair follicle. when contracted, it causes the hair to stand on end.
  • 45. systems • Each system consists of several organs that cooperate to carry out a living process (digestion of food). • 11 major systems in humans: 1. Nervous system  Major organs: brain, spinal cord, nerves
  • 46. Main functions: detects stimuli, formulates responses, transmits nerve impulses and integrates the activities of systems. Controls physiological processes in conjunction with the endocrine system. 2. Skeletal system Major organs: bones, cartilage, tendons, ligaments Major functions: supports the body, provides sites for attachment of muscles, and protection for internal organs.
  • 47. 3. Circulatory system Major organs: heart, blood vessels, blood Main functions: delivers nutrients, respiratory gases and hormones to body cells. Transports waste products to excretory organs. 4. Digestive system Major organs: mouth, pharynx, esophagus, stomach, liver, pancreas, small and large intestines, anus. Main functions: ingests and digests food, absorbs nutrients for use by the body and eliminates undigested material.
  • 48. 5. Respiratory system Major organs: nose, trachea, lungs Main functions: provides a surface area for gases exchange between the blood and the external environment. Allows oxygen intake and carbon dioxide elimination. 6. Excretory system Major organs: kidneys, ureters, urinary bladder, urethra, skin, lungs. Main functions: removes metabolic waste products (urea and carbon dioxide). Regulates the osmotic balance of the blood.
  • 49. 7. Reproductive system Major organs: male (testes, seminal vesicles, penis), female (ovaries, Fallopian tubes, uterus, cervix, vagina) Main functions: male (produces sperms and male hormones), female (produces ova, nurtures developing foetuses, and produces female hormones.
  • 50. 8. Muscular system Major organs: skeletal muscles, smooth muscles and cardiac muscles Main functions: contraction of muscles enables body movements. 9. Integumentary system Major organs: skin Main functions: physically separates the body from the external environment. Protects the body against mechanical injuries, microbial infection and dehydration.
  • 51. 10. Endocrine system Major organs: glands (pituitary, thyroid, adrenal and pancreas) secrete hormones. Main functions: coordinates body activities in conjunction with the nervous system. 11. Lymphatic system Major organs: lymph vessels, lymph nodes, bone marrow, thymus. Main functions: defends the body against infections. Returns tissues fluid to the blood.
  • 52. • An organ may belong to more than one system. Example: pancreas secretes hormones and pancreatic juice. Pancreas is a part of the endocrine system and the digestive system. • All systems combine to form a multicellular organism.
  • 53. Cell organisation in plants • Plant cells also undergo cell specialisation. • plant cells undergo differentiation and become specialised in structure and function: 1. Mesophyll palisade cells  Consist of elongated, cylindrical cells, arranged vertically and close to one another, situated just below the upper epidermis. This allow as much light as possible to reach the chloroplasts for photosynthesis.
  • 54. Contain a large number of chloroplasts for maximum absorption of sunlight. 2. Xylem vessels No cytoplasm, hence, water can pass freely. The end walls of the cells are perforated, and the cells form a continuous vessel or tube which allows water and mineral salts to be transported in the plant.
  • 55. 3. Guard cells Specialised epidermal cells at the lower epidermis which are kidney-shaped when turgid. Control the size of the stoma by changing their shape. 4. Root hairs Have a long extension which increases the surface area for absorption of minerals and water from the soil.
  • 56. • 2 main types of tissues (meristematic tissues and permanent tissues) form plant organs (leaves, stems and roots). 1. Meristematic tissues Consists of small cells which have thin walls, large nuclei, dense cytoplasm and no vacuoles. Comprise young and actively dividing cells which have not undergone differentiation.
  • 57. Apical meristems are located at the tips of roots and the buds of shoots. The tissues undergo mitotic cell division to increase the number of cells for plant growth. Lateral meristems/cambia are found in the peripheral areas of stems and roots. They are responsible for secondary growth which adds girth to the plants.
  • 58. 2. Permanent tissues Consist of more mature cells that are either undergoing differentiation or have already undergone differentiation. 3 types of permanent tissues: a) Epidermal tissue  Characteristics i. Forms the epidermis (the outermost layer that covers the stems, leaves and roots of young plants). This tissues also covers the flowers, fruits and seeds.
  • 59. ii. The walls of epidermal cells which are exposed to air are normally covered by a waxy, waterproof coating called the cuticle. iii. Most are flat and have large vacuoles.  Functions i. The cuticle helps prevent the loss of excessive water through evaporation, protects the plant from mechanical injury and prevents invasion by disease-causing microorganisms.
  • 60. ii. In roots, some have long projections called root hairs. These specialised structures increase the surface area for absorption of water and minerals. iii. In leaves, the lower epidermis contains specialised cells (guard cells) which surround the stomata.
  • 61. b) Ground tissue Forms the bulk of a plant. 3 types of ground tissues: 1) Parenchyma tissue  Characteristics i. Consists of thin-walled cells which are loosely arranged with spaces between them. ii. cells have a large vacuole. iii. The least specialised cells and can be found in all the organs of a plant.
  • 62.  Functions i. Parenchyma cells store products of photosynthesis (sugar and starch). ii. The palisade mesophyll cells and spongy mesophyll cells in leaves are specialised parenchyma cells which contain chloroplasts and carry out photosynthesis. iii. Gives support and shape to plants.
  • 63. 2) Collenchyma tissue  Characteristics i. Consists of elongated, polygonal cells with unevenly thickened cell walls (thickened by cellulose and pectin. Strong and flexible).  Functions i. an important source of support in herbaceous plants, young stems, leaf stalks and petioles.
  • 64. 3) Sclerenchyma tissue  Characteristics i. Sclerenchyma cells are much more rigid than collenchyma cells because they have cell walls which are uniformly thickened by lignin. ii. Most of the cells are dead at maturity.  Functions i. Supports and strengthens the plant body and provides protection to the plant.
  • 65. c) Vascular tissue Vascular tissues (are continuous throughout the plant) are involved in the transport of substances between the roots and shoots. 2 types of vascular tissues: 1) Xylem tissue  characteristics i. Xylem consists of tracheids and xylem vessels. these are long tubes joined together end to end, stretching from the roots right up to the shoots.
  • 66. ii. The cell walls of the xylem are thickened with lignin which prevents food substances from entering the cells. iii. Dies upon reaching maturity. iv. When the cytoplasm disintegrates, a hollow tube is left behind. This allows water and minerals to flow easily through the xylem vessels.
  • 67.  Functions i. Xylem conducts water and minerals from the roots to the leaves. ii. It provides support and mechanical strength to the plant.
  • 68. 2) Phloem tissue  Characteristics i. Consists of parenchyma cells, sclereids, sieve tubes and companion cells. ii. The conducting cells of phloem are the sieve tubes (have pores at both ends, called sieve plates. Obtain nutrients and energy from the adjacent companion cells).  Functions i. Phloem transports organic nutrients (carbohydrates and amino acids) downwards from the leaves to storage organs and growing parts of plants.
  • 69. Organs and systems in plants • Plant organs: leaves, stems, roots and flowers. • Systems in plants are not specialised as those of animals. Plants have fewer organs as compared to animals.
  • 70. • Flowering plants (angiosperms) consist of 2 main systems: 1. Root system  Is the absorptive system of a plant. The roots are highly branched to absorb water and minerals from the soil and transport them to the main vascular system (xylem).  the roots anchor the plant to the ground.
  • 71. 2. Shoot system Consists of organs (stems, leaves, buds, flowers and fruits). Stems and branches act as a support system for the plant by holding the leaves in a position that facilitate maximum absorption of sunlight during photosynthesis. They also position the flowers for pollination.
  • 72. Leaves are made of ground tissue, epidermal tissue, mesophyll tissue and vascular tissue. They form the main photosynthetic system (synthesises organic compounds required for plant growth). The products of photosynthesis are transported via the vascular system (phloem) to other parts of plants. Reproductive system of plants consists of flowers which produce fruits after fertilisation has taken place.
  • 73. The internal environment of multicellular organisms • Although multicellular organism lives in external environment, the cells of its body live within internal environment (consists of the interstitial fluid and blood plasma). • interstitial fluid fills the spaces between the cells and constantly bathes the cells. • Nutrients and waste substances are exchanged between the interstitial fluid and the blood plasma (contained in the blood capillaries).
  • 74. The necessity for maintaining optimal internal environment • In order for cells of the body to function optimally, the physical factors and the chemical composition within the internal environment must be maintained at relatively constant level regardless of the conditions outside the cells. • Physical factors: temperature, blood pressure, osmotic. • Chemical factors: salt and sugar contents, pH.
  • 75. • Homeostasis is the maintenance of a relatively constant internal environment for the optimal functions of cells. • In humans and animals, mechanism of homeostasis maintain the physical factors and chemical factors of the internal environment at steady state with minimal fluctuations.
  • 76. In homeostatic control mechanism, the change in internal environment detected receptor send message control centre processes information effector (bring about a counter response that reverse the change back to original condition)
  • 77. • in plants, the need for regulatory system is lesser because: a) Most plant cells are dead at functional maturity, so chemical reactions do not take place in these cells. b) Plant cells are not bathed in fluid but surrounded by air. c) Plant cells do not lyse in hypotonic environment because they have cell walls. d) Water movement in plants is aided by natural factors (transpirational pull).
  • 78. The importance of regulating optimal internal environment • Ensure optimal cellular activities at times when the external environment (temperature of environment) changes. • Enable organisms to live in a wider range of habitats. • Metabolic activities and physiological processes can still continue even though the external environment fluctuates substantially.
  • 79. • Organisms can control the metabolic rate according to their needs because any internal fluctuations can be corrected through the homeostatic control system. • Ensure a more efficient and optimal metabolism in the cell. • A stable internal environment allows enzymes to function at optimal rate.
  • 80. The involvement of various system in maintaining optimal internal environment • Physical factors/chemical factors of the internal environment: 1. Body temperature  Systems involved  Integumentary system (skin and sweat glands).  Nervous system  Circulatory system  Muscular system  Endocrine system
  • 81.  Types of regulation Regulate the balance of heat loss and heat gain to maintain stable body temperature of 37oC. When the temperature of the body rises above the normal value, Thermoreceptors in the skin detect the change in temperature. The nervous system conveys the information to the hypothalamus. Then, the information is conveyed to effectors.
  • 82. The effectors involved are: a) Sweat glands: secrete more sweat to cool the body through evaporation. b) Blood vessels: dilate to increase heat loss to the environment. c) Hair erector muscles: relax so as to flatten hair to reduce insulation. d) Thyroid gland: less stimulated, the secretion of thyroxine is reduced and this result in a lower basal metabolic rate.
  • 83. Overall result: lowering of the body temperature to the normal level. On cold day, the opposite mechanism occur.
  • 84. 2. Oxygen and carbon dioxide levels  Systems involved Respiratory system Circulatory system Nervous system  Types of regulation Regulate the concentration of oxygen and carbon dioxide in the bloodstream.
  • 85. circulatory system transports oxygen from the lung to the cells. Carbon dioxide produced during respiration diffuse into the bloodstream and is transported back to the lungs. The change in the concentration of oxygen and carbon dioxide are detected by the nervous system.
  • 86. 3. Blood glucose level  Systems involved Endocrine system (pancreas) Circulatory system Digestive system (liver)  Types of regulation Regulate blood glucose level at a set point of 90 mg per 100 cm3.
  • 87. Pancreas secrete insulin when the level of glucose in the blood rises above the set point. Circulatory system transport insulin to the liver. Insulin stimulate liver cells to convert glucose into glycogen. Blood glucose level drops. When the glucose level falls below the set point, pancreas secrete glucagon (promote the breakdown of glycogen and the release of glucose into the blood).
  • 88. 4. Blood osmotic pressure  Systems involved Nervous system Endocrine system Excretory system Circulatory system  Types of regulation Regulate the amount of water and dissolved substances (mineral salts) in the tissue fluid and blood.
  • 89. 5. pH  Systems involved Respiratory system Circulatory system Excretory system (kidneys)  Types of regulation pH of blood and tissue fluid is maintained at a value of 7.4 by regulating the concentration of hydrogen ions (H+), hydroxyl ions (OH-) and hydrogen carbonate ions (HCO3 -).
  • 90. Appreciating the uniqueness of the cell • Cell: the basic unit of all living organisms and is capable of functioning on its own. • Cellular components of the cell are completely dependent upon one another for the cell to function at optimal level. • The cell as a whole will not be able to function properly if any of its cellular components loses its ability to function normally. Optimal cellular function is the result of cellular order within the cell.
  • 91. • Systems of organisms are able to function efficiently because the cellular components of cells work together and cooperate harmoniously with each other. • This ensure the survival of the organism.