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WHAT IS GOING ON IN HIV AND AIDS IN
         2013 AND BEYOND
        Prof Alan Whiteside

              RATN MEETING
             JOHANNESBURG
               March 2013
Outline

   1. Context: Epidemiology
      •   Where the epidemic is
      •   Hyper-epidemic countries
   2. What does this mean
      •   For development (and MDGs)
      •   Economic growth
      •   Donors
   3. Responding
      •   Prevention (first prize)
      •   Treatment
      •   Impact mitigation
   4. Conclusion
      •   Understand your epidemic
      •   Prioritize
2009 Global HIV Infection
33.3 million people [31.4–35.3 million] living with HIV




2.2
Exceptional Epidemics: Prevalence in Africa
2009 (Adults 15–49)




     Source: UNAIDS Global Report 2010 Geneva: UNAIDS (2009data)
HIV prevalence & no of HIV+ people countries
 with >1% of SSA HIV+ population.




           HIV prevalence and number of HIV positive
           people in countries with 1% or more of the
           total Sub-Saharan African HIV positive
           population. Data from: UNAIDS
           (http://www.unaids.org/en/dataanalysis/epi
           demiology/
DHS HIV Prevalence Swaziland 2006
HIV and AIDS

Country         Number of adults HIV/AIDS
                living with HIV  Prevalence rate

Swaziland       190,000          26.1%

South Africa    5,700,000        18.1%

Botswana        300,000          23.9%
Comparison of Epidemics

•Scale of the epidemic: Southern Africa unbelievably
high over 15%,
•Numbers
•Mode of transmission: SA - unprotected
heterosexual intercourse
•Ability to respond: a function of wealth and political
commitment
What does this mean
 (more)

    •   For development (and
        MDGs)
    •   Economic growth
    •   Donors
Demographics: Population Growth Rate
Beyond the
  MDGs
Responding



    •   Prevention (first prize)
    •   Treatment
    •   Impact mitigation
Epidemic Curves: HIV, AIDS and Impact

     Numbers


               HIV prevalence

                                                              Impact
                                             A2
               A1
 A

                         AIDS - cumulative




 B                  B1




               T1                       T2          Time
                                                                   Epidem’gy& Lit. p. 27
                                                  27Aug01 -Report I:
Logic for Prevention



      1. Growing case load
        • For every two people put on treatment there are
        five new infections
      2. Stretched health systems
        • Lack of buy-in, time for adequate training,
        intervention that ‘speak to’ individuals
      3. Strained human resources
        • 13 providers per 100,000 people in SSA
        • 5,100 new doctors per year in Africa
          (compared to 173,800 in Europe)
      4. Money
AIDS Treatment without prevention is mopping
the floor while the tap is running
What Works in Prevention?


     Currently:
        PMTCT
        Male circumcision
        Male and female condoms
     Potentially:
        Microbicides PREP
        Vaccine
        Cure
        Behaviour change that works
What Should Work in Prevention


     Behaviour change
     Fewer partners
     Less concurrency
     Later sexual debut
     What Needs to be Addressed…
        •   Poverty/ economic inequalities
        •   Gender inequalities
        •   Leadership and policy
        •   Etc.
Total annual resources available for AIDS in low
                          and middle income countries




                                                                                                                           Domestic
                                                                                                                          contribution




Source: UNAIDS analysis based on (1) Kaiser Family Foundation and UNAIDS , financing the Response to AIDS in low and
middle income countries from the G8, European Commission and other Donor Governments in 2009, July 2010; (2)
UNAIDSOECD/DAC online database (last visited on January 05, 2011); (3) Funders Concerned About AIDS (FCAA), 2010; (4)
European HIV/AIDS Funders Group (EFG, 2010; (5) UNAIDS Unified Budget of Work (UBW) for 2010 & 2011); (6) Disbursements
reports and pledges and contributions reports from the GFATM (last visited on Jan 06 2011(7) budget review from Donor
governments and multilateral organizations.
Donor funding for Africa flattened, domestic
funding increasing (UNAIDS)
African Treatment Programmes aid dependent!
Fiscal Space for Health Spending


Health expenditure per capita is predicted by GDP




                                      Source: International
                                      AIDS Society
                                      presentation by van
                                      der Gaag, McGreevey
                                      & Stimac
National Health Expenditures
Global Positioning 2012

The United States:
Terra Nova: How to achieve a successful PEPFAR
Transition in South Africa, A report of the CSIS Global
Health Policy Centre, December 2011

The Global Fund:
Round 11 Cancelled Pledges not met

UNAIDS:
AIDS Dependency Crisis Sourcing African Solutions
AIDS Dependency Crisis: Sourcing
   African Solutions (UNAIDS)
1. Strengthen African ownership, exploit & diversifysources
   • Negotiate long-term predicable money from donors
   • Grow African investments
   • Compact for shared differentiated responsibilities
   • Explore sustainable innovative financing

2. Quality Assured Medicines sooner to those in need

3. Establish centres of excellent for local production of
   medicines in Africa
2007 DHS and 2011 SHIMS
      HIV Prevalence in Swaziland
                         (ages 18-49)



Men: Prevalence by Age              Women: Prevalence by Age
Conclusion


    •   The HIV epidemic is no longer on
        the top of the agenda – it is being
        overtaken and mainstreamed
    •   Understand your epidemic
    •   Prioritize
    •   Be realistic
THANK YOU

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Alan whitside - HEARD

  • 1. WHAT IS GOING ON IN HIV AND AIDS IN 2013 AND BEYOND Prof Alan Whiteside RATN MEETING JOHANNESBURG March 2013
  • 2. Outline 1. Context: Epidemiology • Where the epidemic is • Hyper-epidemic countries 2. What does this mean • For development (and MDGs) • Economic growth • Donors 3. Responding • Prevention (first prize) • Treatment • Impact mitigation 4. Conclusion • Understand your epidemic • Prioritize
  • 3. 2009 Global HIV Infection 33.3 million people [31.4–35.3 million] living with HIV 2.2
  • 4. Exceptional Epidemics: Prevalence in Africa 2009 (Adults 15–49) Source: UNAIDS Global Report 2010 Geneva: UNAIDS (2009data)
  • 5. HIV prevalence & no of HIV+ people countries with >1% of SSA HIV+ population. HIV prevalence and number of HIV positive people in countries with 1% or more of the total Sub-Saharan African HIV positive population. Data from: UNAIDS (http://www.unaids.org/en/dataanalysis/epi demiology/
  • 6. DHS HIV Prevalence Swaziland 2006
  • 7. HIV and AIDS Country Number of adults HIV/AIDS living with HIV Prevalence rate Swaziland 190,000 26.1% South Africa 5,700,000 18.1% Botswana 300,000 23.9%
  • 8. Comparison of Epidemics •Scale of the epidemic: Southern Africa unbelievably high over 15%, •Numbers •Mode of transmission: SA - unprotected heterosexual intercourse •Ability to respond: a function of wealth and political commitment
  • 9. What does this mean (more) • For development (and MDGs) • Economic growth • Donors
  • 11. Beyond the MDGs
  • 12. Responding • Prevention (first prize) • Treatment • Impact mitigation
  • 13. Epidemic Curves: HIV, AIDS and Impact Numbers HIV prevalence Impact A2 A1 A AIDS - cumulative B B1 T1 T2 Time Epidem’gy& Lit. p. 27 27Aug01 -Report I:
  • 14. Logic for Prevention 1. Growing case load • For every two people put on treatment there are five new infections 2. Stretched health systems • Lack of buy-in, time for adequate training, intervention that ‘speak to’ individuals 3. Strained human resources • 13 providers per 100,000 people in SSA • 5,100 new doctors per year in Africa (compared to 173,800 in Europe) 4. Money
  • 15. AIDS Treatment without prevention is mopping the floor while the tap is running
  • 16. What Works in Prevention? Currently: PMTCT Male circumcision Male and female condoms Potentially: Microbicides PREP Vaccine Cure Behaviour change that works
  • 17. What Should Work in Prevention Behaviour change Fewer partners Less concurrency Later sexual debut What Needs to be Addressed… • Poverty/ economic inequalities • Gender inequalities • Leadership and policy • Etc.
  • 18. Total annual resources available for AIDS in low and middle income countries Domestic contribution Source: UNAIDS analysis based on (1) Kaiser Family Foundation and UNAIDS , financing the Response to AIDS in low and middle income countries from the G8, European Commission and other Donor Governments in 2009, July 2010; (2) UNAIDSOECD/DAC online database (last visited on January 05, 2011); (3) Funders Concerned About AIDS (FCAA), 2010; (4) European HIV/AIDS Funders Group (EFG, 2010; (5) UNAIDS Unified Budget of Work (UBW) for 2010 & 2011); (6) Disbursements reports and pledges and contributions reports from the GFATM (last visited on Jan 06 2011(7) budget review from Donor governments and multilateral organizations.
  • 19. Donor funding for Africa flattened, domestic funding increasing (UNAIDS)
  • 21. Fiscal Space for Health Spending Health expenditure per capita is predicted by GDP Source: International AIDS Society presentation by van der Gaag, McGreevey & Stimac
  • 23. Global Positioning 2012 The United States: Terra Nova: How to achieve a successful PEPFAR Transition in South Africa, A report of the CSIS Global Health Policy Centre, December 2011 The Global Fund: Round 11 Cancelled Pledges not met UNAIDS: AIDS Dependency Crisis Sourcing African Solutions
  • 24. AIDS Dependency Crisis: Sourcing African Solutions (UNAIDS) 1. Strengthen African ownership, exploit & diversifysources • Negotiate long-term predicable money from donors • Grow African investments • Compact for shared differentiated responsibilities • Explore sustainable innovative financing 2. Quality Assured Medicines sooner to those in need 3. Establish centres of excellent for local production of medicines in Africa
  • 25. 2007 DHS and 2011 SHIMS HIV Prevalence in Swaziland (ages 18-49) Men: Prevalence by Age Women: Prevalence by Age
  • 26. Conclusion • The HIV epidemic is no longer on the top of the agenda – it is being overtaken and mainstreamed • Understand your epidemic • Prioritize • Be realistic

Editor's Notes

  1. This slide needs updating
  2. By 2009-10, approximately one third of the total investment was from domestic public budgets, mostly in the middle-income countriesApproximately a further one third was in the form of technical assistance, and not directly spent in countries
  3. In both prevalence among 18-49 is 31%. Decline in youth rates.