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Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012
Published on December 2012

                                                                                                             Report Summary

Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012


Summary


Global Markets Direct's, 'Bacterial (Pyogenic) Meningitis - Pipeline Review, H2 2012', provides an overview of the indication's
therapeutic pipeline. This report provides information on the therapeutic development for Bacterial (Pyogenic) Meningitis, complete
with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the
therapeutic development for Bacterial (Pyogenic) Meningitis. Bacterial (Pyogenic) Meningitis - Pipeline Review, Half Year is built using
data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor
presentations and featured press releases from company/university sites and industry-specific third party sources, put together by
Global Markets Direct's team.


Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated
disease.


Scope


- A snapshot of the global therapeutic scenario for Bacterial (Pyogenic) Meningitis.
- A review of the Bacterial (Pyogenic) Meningitis products under development by companies and universities/research institutes
based on information derived from company and industry-specific sources.
- Coverage of products based on various stages of development ranging from discovery till registration stages.
- A feature on pipeline projects on the basis of monotherapy and combined therapeutics.
- Coverage of the Bacterial (Pyogenic) Meningitis pipeline on the basis of route of administration and molecule type.
- Key discontinued pipeline projects.
- Latest news and deals relating to the products.


Reasons to buy


- Identify and understand important and diverse types of therapeutics under development for Bacterial (Pyogenic) Meningitis.
- Identify emerging players with potentially strong product portfolio and design effective counter-strategies to gain competitive
advantage.
- Plan mergers and acquisitions effectively by identifying players of the most promising pipeline.
- Devise corrective measures for pipeline projects by understanding Bacterial (Pyogenic) Meningitis pipeline depth and focus of
Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to
enhance and expand business potential and scope.
- Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline.




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                                                                                                            Table of Content

Table of Contents
Table of Contents 2
List of Tables 4
List of Figures 5
Introduction 6
Global Markets Direct Report Coverage 6
Bacterial (Pyogenic) Meningitis Overview 7
Therapeutics Development 8
An Overview of Pipeline Products for Bacterial (Pyogenic) Meningitis 8
Bacterial (Pyogenic) Meningitis Therapeutics under Development by Companies 10
Bacterial (Pyogenic) Meningitis Therapeutics under Investigation by Universities/Institutes 11
Late Stage Products 12
Comparative Analysis 12
Mid Clinical Stage Products 13
Comparative Analysis 13
Pre-Clinical Stage Products 14
Comparative Analysis 14
Bacterial (Pyogenic) Meningitis Therapeutics ' Products under Development by Companies 15
Bacterial (Pyogenic) Meningitis Therapeutics ' Products under Investigation by Universities/Institutes 16
Companies Involved in Bacterial (Pyogenic) Meningitis Therapeutics Development 17
Novartis AG 17
Pfizer Inc. 18
GlycoVaxyn AG 19
Sinovac Biotech Ltd. 20
China National Pharmaceutical Group Corporation 21
Bacterial (Pyogenic) Meningitis ' Therapeutics Assessment 22
Assessment by Monotherapy Products 22
Assessment by Combination Products 23
Assessment by Route of Administration 24
Assessment by Molecule Type 26
Drug Profiles 28
Meningitis Vaccine - Drug Profile 28
Product Description 28
Mechanism of Action 28
R&D Progress 28
Quadrivalent Meningococcal Conjugate Vaccine (MCV4) - Drug Profile 29
Product Description 29
Mechanism of Action 29
R&D Progress 29
MnB rLP2086 - Drug Profile 31
Product Description 31
Mechanism of Action 31
R&D Progress 31
acetaminophen - Drug Profile 33



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Product Description 33
Mechanism of Action 33
R&D Progress 33
Glycerol + Paracetamol - Drug Profile 34
Product Description 34
Mechanism of Action 34
R&D Progress 34
Bexsero - Drug Profile 35
Product Description 35
Mechanism of Action 35
R&D Progress 35
Bexsero - Drug Profile 37
Product Description 37
Mechanism of Action 37
R&D Progress 37
Amphotericin B + Fluconazole - Drug Profile 39
Product Description 39
Mechanism of Action 39
R&D Progress 39
dexamethasone beloxil - Drug Profile 40
Product Description 40
Mechanism of Action 40
R&D Progress 40
Meningococcal Group B Meningitis Vaccine - Drug Profile 41
Product Description 41
Mechanism of Action 41
R&D Progress 41
rLP2086 + Repevax - Drug Profile 42
Product Description 42
Mechanism of Action 42
R&D Progress 42
Conjugated Meningococcal C Vaccine - Drug Profile 44
Product Description 44
Mechanism of Action 44
R&D Progress 44
Pneumococcal Vaccine - Drug Profile 46
Product Description 46
Mechanism of Action 46
R&D Progress 46
Pneumococcal Vaccine - Drug Profile 47
Product Description 47
Mechanism of Action 47
R&D Progress 47
Vi-CRM197 PCMV - Drug Profile 48
Product Description 48
Mechanism of Action 48
R&D Progress 48
Bacterial (Pyogenic) Meningitis Therapeutics ' Drug Profile Updates 49



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Bacterial (Pyogenic) Meningitis Therapeutics - Dormant Products 52
Bacterial (Pyogenic) Meningitis ' Product Development Milestones 53
Featured News & Press Releases 53
Feb 07, 2012: Novartis's Pivotal Study Confirms Potential Of Candidate Vaccine Bexsero To Help Protect Infants Against Devastating
Meningococcal Serogroup B Disease 53
Jun 09, 2011: Novartis's Bexsero Shows Significant Potential In Providing Broad Coverage Against Meningococcal Serogroup B
Infections 54
Appendix 57
Methodology 57
Coverage 57
Secondary Research 57
Primary Research 57
Expert Panel Validation 57
Contact Us 58
Disclaimer 58




List of Tables


Number of Products Under Development for Bacterial (Pyogenic) Meningitis, H2 2012 8
Products under Development for Bacterial (Pyogenic) Meningitis ' Comparative Analysis, H2 2012 9
Number of Products under Development by Companies, H2 2012 10
Number of Products under Investigation by Universities/Institutes, H2 2012 11
Comparative Analysis by Late Stage Development, H2 2012 12
Comparative Analysis by Mid Clinical Stage Development, H2 2012 13
Comparative Analysis by Pre-Clinical Stage Development, H2 2012 14
Products under Development by Companies, H2 2012 15
Products under Investigation by Universities/Institutes, H2 2012 16
Novartis AG, H2 2012 17
Pfizer Inc., H2 2012 18
GlycoVaxyn AG, H2 2012 19
Sinovac Biotech Ltd., H2 2012 20
China National Pharmaceutical Group Corporation, H2 2012 21
Assessment by Monotherapy Products, H2 2012 22
Assessment by Combination Products, H2 2012 23
Assessment by Stage and Route of Administration, H2 2012 25
Assessment by Stage and Molecule Type, H2 2012 27
Bacterial (Pyogenic) Meningitis Therapeutics ' Drug Profile Updates 49
Bacterial (Pyogenic) Meningitis Therapeutics ' Dormant Products 52




List of Figures


Number of Products under Development for Bacterial (Pyogenic) Meningitis, H2 2012 8
Products under Development for Bacterial (Pyogenic) Meningitis ' Comparative Analysis, H2 2012 9
Products under Development by Companies, H2 2012 10



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Products under Investigation by Universities/Institutes, H2 2012 11
Late Stage Products, H2 2012 12
Mid Clinical Stage Products, H2 2012 13
Pre-Clinical Stage Products, H2 2012 14
Assessment by Monotherapy Products, H2 2012 22
Assessment by Combination Products, H2 2012 23
Assessment by Route of Administration, H2 2012 24
Assessment by Stage and Route of Administration, H2 2012 25
Assessment by Molecule Type, H2 2012 26
Assessment by Stage and Molecule Type, H2 2012 27




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Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012

  • 1. Find Industry reports, Company profiles ReportLinker and Market Statistics >> Get this Report Now by email! Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012 Published on December 2012 Report Summary Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012 Summary Global Markets Direct's, 'Bacterial (Pyogenic) Meningitis - Pipeline Review, H2 2012', provides an overview of the indication's therapeutic pipeline. This report provides information on the therapeutic development for Bacterial (Pyogenic) Meningitis, complete with latest updates, and special features on late-stage and discontinued projects. It also reviews key players involved in the therapeutic development for Bacterial (Pyogenic) Meningitis. Bacterial (Pyogenic) Meningitis - Pipeline Review, Half Year is built using data and information sourced from Global Markets Direct's proprietary databases, Company/University websites, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources, put together by Global Markets Direct's team. Note*: Certain sections in the report may be removed or altered based on the availability and relevance of data for the indicated disease. Scope - A snapshot of the global therapeutic scenario for Bacterial (Pyogenic) Meningitis. - A review of the Bacterial (Pyogenic) Meningitis products under development by companies and universities/research institutes based on information derived from company and industry-specific sources. - Coverage of products based on various stages of development ranging from discovery till registration stages. - A feature on pipeline projects on the basis of monotherapy and combined therapeutics. - Coverage of the Bacterial (Pyogenic) Meningitis pipeline on the basis of route of administration and molecule type. - Key discontinued pipeline projects. - Latest news and deals relating to the products. Reasons to buy - Identify and understand important and diverse types of therapeutics under development for Bacterial (Pyogenic) Meningitis. - Identify emerging players with potentially strong product portfolio and design effective counter-strategies to gain competitive advantage. - Plan mergers and acquisitions effectively by identifying players of the most promising pipeline. - Devise corrective measures for pipeline projects by understanding Bacterial (Pyogenic) Meningitis pipeline depth and focus of Indication therapeutics. - Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope. - Modify the therapeutic portfolio by identifying discontinued projects and understanding the factors that drove them from pipeline. Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012 (From Slideshare) Page 1/7
  • 2. Find Industry reports, Company profiles ReportLinker and Market Statistics >> Get this Report Now by email! Table of Content Table of Contents Table of Contents 2 List of Tables 4 List of Figures 5 Introduction 6 Global Markets Direct Report Coverage 6 Bacterial (Pyogenic) Meningitis Overview 7 Therapeutics Development 8 An Overview of Pipeline Products for Bacterial (Pyogenic) Meningitis 8 Bacterial (Pyogenic) Meningitis Therapeutics under Development by Companies 10 Bacterial (Pyogenic) Meningitis Therapeutics under Investigation by Universities/Institutes 11 Late Stage Products 12 Comparative Analysis 12 Mid Clinical Stage Products 13 Comparative Analysis 13 Pre-Clinical Stage Products 14 Comparative Analysis 14 Bacterial (Pyogenic) Meningitis Therapeutics ' Products under Development by Companies 15 Bacterial (Pyogenic) Meningitis Therapeutics ' Products under Investigation by Universities/Institutes 16 Companies Involved in Bacterial (Pyogenic) Meningitis Therapeutics Development 17 Novartis AG 17 Pfizer Inc. 18 GlycoVaxyn AG 19 Sinovac Biotech Ltd. 20 China National Pharmaceutical Group Corporation 21 Bacterial (Pyogenic) Meningitis ' Therapeutics Assessment 22 Assessment by Monotherapy Products 22 Assessment by Combination Products 23 Assessment by Route of Administration 24 Assessment by Molecule Type 26 Drug Profiles 28 Meningitis Vaccine - Drug Profile 28 Product Description 28 Mechanism of Action 28 R&D Progress 28 Quadrivalent Meningococcal Conjugate Vaccine (MCV4) - Drug Profile 29 Product Description 29 Mechanism of Action 29 R&D Progress 29 MnB rLP2086 - Drug Profile 31 Product Description 31 Mechanism of Action 31 R&D Progress 31 acetaminophen - Drug Profile 33 Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012 (From Slideshare) Page 2/7
  • 3. Find Industry reports, Company profiles ReportLinker and Market Statistics >> Get this Report Now by email! Product Description 33 Mechanism of Action 33 R&D Progress 33 Glycerol + Paracetamol - Drug Profile 34 Product Description 34 Mechanism of Action 34 R&D Progress 34 Bexsero - Drug Profile 35 Product Description 35 Mechanism of Action 35 R&D Progress 35 Bexsero - Drug Profile 37 Product Description 37 Mechanism of Action 37 R&D Progress 37 Amphotericin B + Fluconazole - Drug Profile 39 Product Description 39 Mechanism of Action 39 R&D Progress 39 dexamethasone beloxil - Drug Profile 40 Product Description 40 Mechanism of Action 40 R&D Progress 40 Meningococcal Group B Meningitis Vaccine - Drug Profile 41 Product Description 41 Mechanism of Action 41 R&D Progress 41 rLP2086 + Repevax - Drug Profile 42 Product Description 42 Mechanism of Action 42 R&D Progress 42 Conjugated Meningococcal C Vaccine - Drug Profile 44 Product Description 44 Mechanism of Action 44 R&D Progress 44 Pneumococcal Vaccine - Drug Profile 46 Product Description 46 Mechanism of Action 46 R&D Progress 46 Pneumococcal Vaccine - Drug Profile 47 Product Description 47 Mechanism of Action 47 R&D Progress 47 Vi-CRM197 PCMV - Drug Profile 48 Product Description 48 Mechanism of Action 48 R&D Progress 48 Bacterial (Pyogenic) Meningitis Therapeutics ' Drug Profile Updates 49 Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012 (From Slideshare) Page 3/7
  • 4. Find Industry reports, Company profiles ReportLinker and Market Statistics >> Get this Report Now by email! Bacterial (Pyogenic) Meningitis Therapeutics - Dormant Products 52 Bacterial (Pyogenic) Meningitis ' Product Development Milestones 53 Featured News & Press Releases 53 Feb 07, 2012: Novartis's Pivotal Study Confirms Potential Of Candidate Vaccine Bexsero To Help Protect Infants Against Devastating Meningococcal Serogroup B Disease 53 Jun 09, 2011: Novartis's Bexsero Shows Significant Potential In Providing Broad Coverage Against Meningococcal Serogroup B Infections 54 Appendix 57 Methodology 57 Coverage 57 Secondary Research 57 Primary Research 57 Expert Panel Validation 57 Contact Us 58 Disclaimer 58 List of Tables Number of Products Under Development for Bacterial (Pyogenic) Meningitis, H2 2012 8 Products under Development for Bacterial (Pyogenic) Meningitis ' Comparative Analysis, H2 2012 9 Number of Products under Development by Companies, H2 2012 10 Number of Products under Investigation by Universities/Institutes, H2 2012 11 Comparative Analysis by Late Stage Development, H2 2012 12 Comparative Analysis by Mid Clinical Stage Development, H2 2012 13 Comparative Analysis by Pre-Clinical Stage Development, H2 2012 14 Products under Development by Companies, H2 2012 15 Products under Investigation by Universities/Institutes, H2 2012 16 Novartis AG, H2 2012 17 Pfizer Inc., H2 2012 18 GlycoVaxyn AG, H2 2012 19 Sinovac Biotech Ltd., H2 2012 20 China National Pharmaceutical Group Corporation, H2 2012 21 Assessment by Monotherapy Products, H2 2012 22 Assessment by Combination Products, H2 2012 23 Assessment by Stage and Route of Administration, H2 2012 25 Assessment by Stage and Molecule Type, H2 2012 27 Bacterial (Pyogenic) Meningitis Therapeutics ' Drug Profile Updates 49 Bacterial (Pyogenic) Meningitis Therapeutics ' Dormant Products 52 List of Figures Number of Products under Development for Bacterial (Pyogenic) Meningitis, H2 2012 8 Products under Development for Bacterial (Pyogenic) Meningitis ' Comparative Analysis, H2 2012 9 Products under Development by Companies, H2 2012 10 Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012 (From Slideshare) Page 4/7
  • 5. Find Industry reports, Company profiles ReportLinker and Market Statistics >> Get this Report Now by email! Products under Investigation by Universities/Institutes, H2 2012 11 Late Stage Products, H2 2012 12 Mid Clinical Stage Products, H2 2012 13 Pre-Clinical Stage Products, H2 2012 14 Assessment by Monotherapy Products, H2 2012 22 Assessment by Combination Products, H2 2012 23 Assessment by Route of Administration, H2 2012 24 Assessment by Stage and Route of Administration, H2 2012 25 Assessment by Molecule Type, H2 2012 26 Assessment by Stage and Molecule Type, H2 2012 27 Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012 (From Slideshare) Page 5/7
  • 6. Find Industry reports, Company profiles ReportLinker and Market Statistics >> Get this Report Now by email! Fax Order Form To place an order via fax simply print this form, fill in the information below and fax the completed form to: Europe, Middle East and Africa : + 33 4 37 37 15 56 Asia, Oceania and America : + 1 (805) 617 17 93 If you have any questions please visit http://www.reportlinker.com/notify/contact Order Information Please verify that the product information is correct and select the format(s) you require. Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012 Product Formats Please select the product formats and the quantity you require. 1 User License--USD 2 000.00 Quantity: _____ Site License--USD 4 000.00 Quantity: _____ Corporate License--USD 6 000.00 Quantity: _____ Contact Information Please enter all the information below in BLOCK CAPITALS Title: Mr Mrs Dr Miss Ms Prof First Name: _____________________________ Last Name: __________________________________ Email Address: __________________________________________________________________________ Job Title: __________________________________________________________________________ Organization: __________________________________________________________________________ Address: __________________________________________________________________________ City: __________________________________________________________________________ Postal / Zip Code: __________________________________________________________________________ Country: __________________________________________________________________________ Phone Number: __________________________________________________________________________ Fax Number: __________________________________________________________________________ Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012 (From Slideshare) Page 6/7
  • 7. Find Industry reports, Company profiles ReportLinker and Market Statistics >> Get this Report Now by email! Payment Information Please indicate the payment method, you would like to use by selecting the appropriate box. Payment by credit card Card Number: ______________________________________________ Expiry Date __________ / _________ CVV Number _____________________ Card Type (ex: Visa, Amex…) _________________________________ Payment by wire transfer Crédit Mutuel RIB : 10278 07314 00020257701 89 BIC : CMCIFR2A IBAN : FR76 1027 8073 1400 0202 5770 189 Payment by check UBIQUICK SAS 16 rue Grenette – 69002 LYON, FRANCE Customer signature:   Please note that by ordering from Reportlinker you are agreeing to our Terms and Conditions at http://www.reportlinker.com/index/terms Please fax this form to: Europe, Middle East and Africa : + 33 4 37 37 15 56 Asia, Oceania and America : + 1 (805) 617 17 93 Bacterial (Pyogenic) Meningitis ' Pipeline Review, H2 2012 (From Slideshare) Page 7/7