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Samidirect business-manual
- 1. Sami Labs Worldwide Healthy, Wealthy & Wise ............. ............................................................................................. ..................................... ................................................................................................................................................................. ................................................................................................................................................................. ................................................................................................................................................................. ................................................................................................................................................................. ................................................................................................................................................................. 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No. 30 & 31, 5th Cross,5th Block, Tel: 91 80 4038 1800 Koramangala, Bangalore - 560034, Fax: 91 80 4038 1838 Karnataka, India. info@samidirect.com Healthy, Wealthy & Wise www.samidirect.com
- 2. Founder speaks Dr. Muhammed Majeed “ Dear Friend, Congratulations on your decision! A little over 3 decades ago, I went from a small town of South India to the United States of America seeking fulfillment of my dreams. Today, with a business conglomerate spread Dr. Muhammed Majeed is the inspiration and motivation across the world, I can confidently say that the future belongs to those who believe in the behind Sami and the Sabinsa Group of Companies. Dr. Majeed beauty of their dreams. has a Ph.D in Industrial Pharmacy. After a decade and half of The aspiration to dream and the conviction to follow their dreams is what sets apart the working with respected names in the American pharmaceutical extraordinary from the ordinary. Congratulations for choosing to be among the industry, Dr. Majeed first set up Sabinsa Corporation in New extraordinary. Jersey, USA in 1988. He later set up Sami Labs Limited Bangalore, Now we are in it together. You have chosen the right place and the right means. The India in 1991, with the vision of research, development and awesome combination of extensively researched products and a revolutionary business marketing of a new genre of products – natural therapeutics. plan is a definite formula for success. Believe me, making money has never been such fun ! We are with you at every step to help you fulfill your dreams and reach greater heights. Over the past two decades, the organization has grown into a “ health science multinational with presence in USA, Europe, India, Japan, Australia, China, UAE, South Africa and Brazil. It Welcome again, employs over a 1000 people with four manufacturing locations in India and one in USA. Its research facility in Bangalore has Dr. Muhammed Majeed over a hundred scientists involved in specialized work in the areas of phytochemistry, organic chemistry, biochemistry, tissue culture and plant biotechnology. Today, Sami holds a strong intellectual property portfolio with several US and international patents to its credit apart from awards and recognitions worldwide.
- 3. From the desk of the CEO Mr. Rajesh Kumar, CEO “ Welcome on board Sami Direct. As we embark on this journey of fulfilling the dreams of our Business Associates by bringing nutrition to everyday life , we are glad to have you with us. Sami Direct is the culmination of relentless Research and development for over 22 years. We at Sami Direct are committed to offer you an unrivalled range of Nutraceutical followed Where by cosmeceutical products which has been acknowledged by the world over for its highest quality and safety standards. innovation is a tradition In Nature lies the power… to heal and to protect. A truth With the perfect blend of world class products and a revolutionary business plan, for you it is a lifetime opportunity not just to enhance your health, but a fruitful and lasting career that our ancestors had known and practiced centuries ago which would heighten your income. has only now come to the understanding of the modern generation. Sami was born out of this realization, and exists Your journey as an independent Entrepreneur will be supported by extensive training for the sole purpose of bringing the healing power of programmes by the masters themselves as a step by step guide in realizing and fulfilling your dreams, and to top it all recognition and rewards for every milestone that you reach. Nature to cure and nurture human life. Our team of professionals with proven experience in the industry whose constant The miraculous properties of nature can be fully extracted endeavour will be to offer solutions which are most beneficial to its distributors & only through innovative use of scientific technology. Thus, customers. A thousand mile journey starts with the single step, and I am confident that based on market-oriented research, the company you have taken the right step. integrates modern scientific techniques with ancient I wish you great success and great health. wisdom of Ayurvedic herbal armamentariums to produce Once again I welcome you on board. new drug molecules – health solutions that have brought back smiles to millions of faces around the world. Yours Truly, As one of the world's largest health science company, the Rajesh Kumar Sami Group has a responsibility towards the people. Through innovative research, deep understanding of the market and production excellence, Sami Labs Ltd. will provide consumers with the best of natural product solutions for a healthier and wealthier life
- 4. Our facilities Manufacturing facility, Kunigal Solid foundation for our dreams Sami Labs has created a benchmark for standardized herbal medicines globally. With six highly advanced, state-of-the-art manufacturing units, which adhere to the strictest quality and safety norms, Sami Labs focuses Super Critical Fluid Extraction Facility, Nelamangala all its efforts towards creating effective and safe products. Every facility is in compliance with rules and regulations. All effluent streams are treated and disposed off significantly. Reflecting the internal system of quality and regulatory requirements, the facilities are certified by National Sanitary Foundation of USA and the Orthodox Union (Kosher) of USA. Its Good Manufacturing Practices (GMP) registration is just one of the many aspects that reflect the company’s commitment to high quality Biotechnology Facility, Nelamangala products. Continuous Extraction Unit, Dobaspet Manufacturing Facility, Hyderabad Sabinsa Manufacturing, Utah, USA Sami Labs, Bangalore, India
- 5. Research & Development Biological Research: This department tests the safety and efficacy of the products developed in the R&D i.e. cosmeceuticals and nutraceutical products. They have developed several in vitro models for testing anti-obesity, anti-diabetic, anti-ageing and several other disease conditions. Non- animal toxicity testing is also undertaken. Analytical R&D: Finding new light It is a key function in the R&D and it supports all the development activities. Recognized by the Department of Scientific and Industrial Research, Sami Their important roles are: R&D is a multi-disciplinary division pursuing diverse fields of research. • Method development The R&D also works closely with the Government of India and the Indian • Validation Pharmacopoeia Committee on preparation of Standard Operating • Development of specification for all products and Procedures for Ayurvedic herbs and monographs for Indian herbs. • Quality control & Quality Assurance Equipped with the best of talent and facilities, Sami research is geared to constantly innovate and sustain high quality output to broaden the Formulations R&D: product portfolio, enrich its intellectual property and build up a robust This department develops natural cosmetic products pipeline of products. that have properties to rejuvenate and protect the skin from environmental pollution, toxic chemicals and Ultraviolet A and B radiation resulting in wrinkling, hyper pigmentation (excessive tanning) and inflammations (sunburn). The department also develops dosage Natural Drug Division: formulations in capsules, tablets etc for the This division focuses on identifying, isolating and nutraceutical products. developing drugs from various natural source having a potential to become a drug. Phytochemistry: Biotechnology: This division does the isolation and development of Sami Labs ventured into Biotechnology in the year 2000. active ingredients from herbs for various nutraceutical LactoSpore® is the first commercial production using the and therapeutic applications. in-house R&D technology. This division is currently involved in the production of high-value enzymes as well as other probiotics . Synthetic Chemistry : Sami Labs has set up a strong synthetic chemistry division to manufacture some of the synthetically derived nutraceuticals. This division currently works on: Tissue Culture: The scientists here develop high-yielding varieties of • Development of drug and drug intermediates medicinal plants & multiply them through tissue culture • Development of selenium amino acid techniques in the laboratory. • Development of chiral molecules • Development of peptides for cosmeceuticals
- 6. Intellectual Title Patent No Brand /Ingredient Properties 13. Manufacturing Processes for Se-alkylselenocysteine, US 6,794,537 Methyselene® Se-allylselenocysteine, Se-arylselenocysteine 14. Method of increased bioavailability of nutrients and US 6,849,645 Cosmoperine®(THP) pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives 15. Process for preparing water soluble diterpenes and their US 6,960,300 Forskolin Eye Drops applications. 16. Composition and methods containing bioavailable Se-methyl-L- US 6,982,273 Methyselene® 63 International patents and still growing 17. Selenochysteine for human and veterinary. A Convenient Process of Manufacture For Difluromethylornithine US 6,998,502 Efflornithine We have 63 patents to our credit, as on September 2010. And Related Compounds 18. A Convenient Process of Manufacture For Difluromethylornithine US 7,345,196 Efflornithine And Related Compounds US PATENTS 19. Compositions and Methods containing Allium Sativum Linn, (Garlic) naturally enriched with organic selenium compounds for US 7,014,874 SelenoForce® nutritional supplementation 20. Bioavailable compositions of Natural and Synthetic HCA US 7,063,861 GarCitrin® Title Patent No Brand /Ingredient 21. Compositions and methods containing natural compounds from US 7,160,562 Metformin-Like Compounds non-conventional sources that are useful in maintaining normal 01. Use of Piperine to increase bioavailability of nutritional US 5,536,506 BioPerine® blood sugar levels compounds 22. Convenient stable non-hygroscopic crystalline solid forms of US 7,202,270 Liposol 02. Use of Piperine as a bioavailability enhancer US 5,744,161 BioPerine® racemic and chiral LA-plus salts process for their manufacture and uses 03. Potassium hydroxycitrate for the suppression of appetite and US 5,783,603 Citrin®K induction of weight loss 23. Commercially viable process for high purity of fatty alcohol C24 to US 7,217,546 Policosanol C36 and its cosmetic application for skin hair and nails 04. Novel Method of preparing a Forskolin composition from US 5,804,596 ForsLean® Forskolin extract and use of Forskolin for promoting lean body 24. Process for the synthesis of biologically active oxygenated US 7,253,324 Stilbenes mass and treating mood disorders compounds by dealkylation of the corresponding alkylethers 05. Bioprotectant composition, method of use and extraction US 5,861,415 Curcumin C3 Complex® 25. Method of preparation and use of coconut water in mammalian US 7,300,682 Cococin™ process of Curcuminoids tissue nourishment, growth, and healthy maintenance 06. Use of Piperine as a bioavailability enhancer US 5,972,382 BioPerine® 26. New Chemical entities with multiple modes of anti-inflammatory US 7,371,889 AKBBA+NSAIDS action 07. Process for making high purity piperine for nutritional use US 6,054,585 BioPerine® 27. New Chemical entities with multiple modes of anti-inflammatory US 7,378,442 AKBBA+NSAIDS 08. Composition and method containing products extracted from US 6,436,991 Gugulipid® action Commiphora Sp. for prevention and treatment of abnormal cell growth and proliferation in inflammation, neoplasia and 28. Process for the Manufacture of Chiral And Racemic Forms of 3- US 7,514,573 3-Aminotetrahydrofurans cardiovascular disease Aminotetrahydrofurans, their Salts and Derivatives 09. Composition and methods containing an antimicrobial essential US 6,607,712 Coleus Oil 29. Non-cytotoxic synthetic analogues of (1E, 6E )-1,7-Bis (4 hydroxy- US 7521580 Curcumin C3 Complex oil extracted from Coleus Forskohlii. 3-methoxyphenyl)-1,6-heptadiene-3, 5-dione and therapeutic applications thereof in cystic fibrosis) 10. Cross regulin composition of turmeric-derived US 6,653,327 Tetrahydrocurcuminoids Tetrahydrocurcuminoids for skin lightening and protection 30. Composition and methods for the management of US 7582314 against UVB rays hyperproliferative dermatological conditions 11. Process of obtaining composition of stable lutein and lutein US 6,689,400 ZeaLutein® derivatives 12. Process for the production of potassium hydroxy citric acid and US 6,770,782 Citrin® K compositions containing the potassium hydroxy citric acid
- 7. Intellectual Title Patent No Brand /Ingredient Properties 16. Use of Piperine as a Bioavailability Enhancer JP3953513 BioPerine® 17. Method of increased bioavailability of nutrients and JP4098985 Cosmoperine®(THP) pharmaceutical preparations with tetrahydropiperine and its analogues and derivatives 18. Bioavailable compositions of Natural and Synthetic HCA JP4205943 GarCitrin® 19. Process of obtaining composition of stable lutein and lutein JP4227409 ZeaLutein® derivatives 20. Process of preparing water soluble diterpenes and their MX260326 Forskolin Eye Drops applications 21. Use of tetrahydrocurcuminoids to regulate physiological and NZ514884 Tetrahydrocurcuminoids pathological events in the skin and mucosa 22. Bioavailable compositions of Natural and Synthetic HCA NZ518116 GarCitrin® 23. Compositions and methods for the management of NZ552027 INTERNATIONAL PATENTS hyperproliferative dermatological conditions 24. Composition for physiological increase of male and female NZ552997 Forskolin hormones with diterpene forskolin and its derivatives Title Patent No Brand /Ingredient 25. Process For Preparing Water Soluble Diterpenes And Their NZ545765 Forskolin Eye Drops Applications 01. Use of Tetrahydrocurcuminoids to Regulate Physiological and AU2006235807 Tetrahydrocurcuminoids 26. Commercial Process for Making Forskolin and its Derivatives NZ568652 Forskolin-Div1 Pathological Events in the Skin and Mucosa 27. Process for preparing water soluble diterpenes and their PH/12006500481 Forskolin Eye Drops 02. Bioavailable compositions of Natural and Synthetic HCA AU773081 GarCitrin® applications 03. Use of Piperine as a Bioavailability Enhancer CA2247467 BioPerine® 28. Process for Preparing Water Soluble Diterpenes and Their RU12836 Forskolin Eye Drops Applications 04. Forskolin for promoting Lean Body Mass CA2281562 ForsLean® 29. Compositions and methods for the management of RU2366412 05. Use of Piperine as a bioavailability enhancer EP0810868 BioPerine® hyperproliferative dermatological conditions 06. Bioprotectant composition, method of use and extraction EP0839037 Curcumin C3 Complex® 30. Process of preparing water soluble diterpenes and their SG121197 Forskolin Eye Drops process of Curcuminoids applications 07. Forskolin For Promoting Lean Body Mass EP0977564 ForsLean® 31. Compositions and methods for the management of SG136165 08. Use of Tetrahydrocurcuminoids to Regulate Physiological and EP1171144 Tetrahydrocurcuminoids hyperproliferative dermatological conditions Pathological Events in the Skin and Mucosa 32. Process for preparing water soluble diterpenes and their ZA2006/01898 Forskolin Eye Drops 09. Bioavailable compositions of Natural and Synthetic HCA EP1254209 GarCitrin® applications 10. Coconut water and its method of preparation EP1341547 Cococin™ 33. Composition and methods for the management of ZA2007/0694 hyperproliferative dermatological Conditions. 11. Process of making and method of use of tetrahydrocurcuminoids EP1328263 Tetrahydrocurcuminoids to regulate physiological and pathological events in the skin and mucosa cells 12. Method of increased bioavailability of nutrients and GB2380675 Cosmoperine®(THP) pharmaceutical preparations with tetrahydropiperine and its AU-Australia JP-Japan SG-Singapore analogues and derivatives CA-Canada MX-Mexico US-United States 13. A process for obtaining high purity fatty alcohols IN229695 Policosanol EP-Europe NZ-New Zealand ZA-South Africa 14. A method for solubilizing forskolin and a composition thereof IN235492 Forskolin Eye Drops GB-Great Britain PH-Philippines 15. A Process of preparing a synergistic composition for treating IN238950 hyperproliferative dermatological conditions. IN-India RU-Russia
- 8. Recognition The proof of excellence 2009: Sabinsa Received Thomas Alva Edison Patent Award for GarCitrin from Research & Development Council of New Jersey , USA 2005: Sabinsa Received Thomas Alva Edison Patent Award for Tetrahydropiperine from Research & Development Council of New Jersey , USA 2008: Dr. Majeed receiving the Certificate of Excellence for Exports from Federation of Indian Export Organisations. 2004: Sabinsa Received Thomas Alva Edison Patent Award for ForsLean from Research & Development 1996-97: Dr. Majeed receiving the National Award Council of New Jersey , USA from (Late) Dr. Shankar Dayal Sharma, President of India, awarded by Spice Board. 2008: Export Excellence Award. 1994: Dr. Majeed receiving the National Award for Quality and Innovation (Basic Drugs) from (Late) Dr. Shankar Dayal Sharma, President of India. 1998-99: Certificate of Honour for Outstanding 2002: Dr. Majeed receives DSIR Award for R&D efforts Performance in the Export of Spices/Spice Products in the category of "Chemical and Allied Industries" from India issued by Spices Board. 2008: Certificate of Excellence for Export Achievement from the Ministry of Commerce, Government of India 2006-07: Dr. Majeed receiving the Export Excellence being received by Mr. K.B. Siva Prakash. Award from Federation of Karnataka Chamber of Commerce & Industry.
- 9. Recognition 2008 Sabinsa Corporation is the recipient of Frost & Sullivan’s 2008 North American Personal Care Ingredient Green Excellence of the Year Award. The award is in acknowledgment of Sabinsa’s strategically balanced green product offering, proactive and sustainable marketing practices, and the continuous ability to The proof of excellence satisfy client needs in an increasingly diverse and green-conscious market space 2006 Sabinsa Corporation was awarded by Nutrition Business Journal (NBJ) * A product merit award for their branded L –(+) – Selenomethionine compound, Selenium SeLECT® * An investment in science and Research award for Forslean® , the company’s branded and patented coleus forskohlii extract ingredient used to improve body composition. NBJ is a research, publishing and consulting company serving the nutrition, natural Products and alternative health care industries. 2003 Best Export Award - Overall GOLD 2002 Award for Highest Export of Value Added Spices by Spices Board, Govt. of India, Ministry of Commerce & Industry. 2002 Award for Highest Export of Newly Developed Spice Products by Spices Board, Govt. of India, Ministry of Commerce & Industry. 2004: Dr. Majeed honored with the prestigious Ellis 2002 Export Award in Recognition of Company’s Performance in “Chemicals Category” for the year 2001 – 02 Island Medal of Honor from National Ethnic Coalition by the Federation of Karnataka Chambers of Commerce & Industry (FKCCI) of Organizations, USA. 2002 Award for Excellence in Export Achievement under 100% EOU Scheme in “Agro & Food” Sector in Karnataka from Govt. of India, Ministry of Commerce & Industry for the year 2001-02 2001 Award for Achieving the Highest Export of Newly Developed Value Added Spice Products from India during the year 1999-2000 by Spices Board, Govt. of India, Ministry of Commerce & Industry 2010: Dr. Majeed received the Daniel B. Stateman 2001 Award for Achieving the Highest Export of Value Added Spices from India during the year 1999-2000 by award for distinguished alumni from Dr. David Taft at Spices Board, Govt. of India, Ministry of Commerce & Industry Long Island University’s 121st graduation ceremony in Brooklyn. 2001 Award for Outstanding Performance in the Export of Spices/Spice Products from India during the year 1999-2000 by Spices Board, Govt. of India, Ministry of Commerce & Industry 2001 Approval of In-house Research & Development Unit u/s 35(2AB) of Income-Tax Act 1961 from Govt. of India, Ministry of Science & Technology, Department of Scientific and Industrial research. Dr. Majeed Receiving distinguished alumni Award of 2000 Certificate of Honour for Outstanding Performance in the Export of Spices/Spice Products for the year Trivandrum Medical College from Hon.Vayalar Ravi, 1998 – 99 from India issued by Spices Board, Govt. of India, Ministry of Commerce & Industry Minister for Overseas Indian Affairs. 1997 Recognition of In-house Research & Development facility (Renewable from time to time) 1997 Recognised Export House from Govt. of India, Ministry of Commerce, DGFT, New Delhi. 1995–96 Certificate of Merit for Outstanding Export Performance in Spice Products, Vegetable Extracts, 2009: Mr. Shaheen Majeed, (Marketing Director for Organic Fine Chemicals, Essential Oils, Extracts & Oleoresins,Modified Starches & Enzymes, etc., from Sabinsa) receiving Herbal Industry Leader Award from Govt. of India, Ministry of Commerce. the American Herbal Products Association
- 10. Corporate Social Responsibility Considering the importance of biodiversity of medicinal plants and to maintain the sustainability for future generations, the company has taken up a successful initiative over the last 10 years by undertaking and promoting large scale commercial cultivation of medicinal plants globally. SAMI initiated almost a decade ago, medicinal plant cultivation with a handful of farmers. Over the years this effort has translated into a large scale cultivation model involving more than 40000 acres and supporting thousands of farmer families. Sami supports its farmers with a buy back guarantee , crop insurance, bank finance and ensures they receive a reasonable price for the produce avoiding intermediaries. Today, this successful model is being replicated in Africa and South East Asia.
- 11. Products OsteoStrong ® Women 40+ KEY BENEFITS Healing in myriad ways As women age, the body undergoes many changes and the major concern is Binds at estrogen receptors and menopause, when hormone levels begin to drop and the menstrual cycle ceases. prevent the body from over- producing estradiol Menopause is the permanent cessation of reproductive fertility some time Mimics the action of estrogen & before the end of the natural life span. The decline in estrogen levels associated along with most bio-available form with menopause puts women at increased risk for declining bone density and of calcium, helps in Bone Mineral fractures. Density Osteoporosis literally means porous bone and is sometimes referred to as the Boosts progesterone expression and “silent disease” because bone loss occurs without symptoms. Although help to normalize the body' s osteoporosis can strike at any age, chances of it developing, increases with age. important estrogen to progesterone ratio Sami Direct is a committed to offer you an unrivalled range of Statistics show that one in two women of age 50 and older usually suffer an Nutraceuticals followed by cosmeceuticals which has been acknowledged osteoporosis-related fracture in their lifetime. Fortunately osteoporosis can be by the world over for its highest quality and safety standards. Supported by prevented or treated. our own Sami labs R&D and Clinical Studies, Sami Direct is all set to usher in a novel range of nutraceuticals and cosmeceuticals with a holistic OsteoStrong® by Sami Direct is a health supplement for 40+ women who face an approach in leading the world to better health. increased risk of declining bone density and fractures. Loaded with natural ingredients like Calcium Citrate malate, Soy extract, Red Clover extract and Sami has also developed the strength and infrastructure to offer services in BioPerine®, OsteoStrong® not only strengthens your bones from within but also the areas of: helps prevent osteoporosis and postmenopausal symptoms in women. • Customized Product Development • Formulation Development Each Tablet contains: • Contract research Ingredient Quantity per Tablet • Clinical research Soy extract (40% Isoflavones) 30 mg • Non animal in-vitro efficacy and toxicity studies Red Clover extract 10 mg • Analytical Studies Calcium Citrate malate 500 mg * BioPerine® 5 mg *Patented – US & International Patents Suggested Use : One tablet twice daily References: 1. Ajmandi, Bahram, H, Journal of the American College of Nutrition, Vol. 20, No. 5, 398S–402S (2001). 2. Van de Weijer, P., Isoflavones from red clover (Promensil®) significantly reduce menopausal hot flush symptoms compared with placebo. Maturitas, Volume 42, Issue 3, Page 187.
- 12. Organic Spirulina Liver Support Maintaining Good Health For Healthy Liver KEY BENEFITS KEY BENEFITS Sami Direct’s Orgnanic Spirulina contains Spirulina, a natural source of vitamins, Rich in antioxidant Alcoholism or alcohol dependency is a disease that manifests the following four Provides better ‘morning after’ minerals, antioxidants and other nutrients, in combination with *Bioperine®, a symptoms: craving, loss of control, physical dependence and addiction. Alcohol effects Boosts energy and Cellular Health patented bioavailability enhancer derived from black pepper fruit that enhances hangover, an after-upshot of dehydration and intoxication, is a common their uptake and utilization. Helps to deal with the symptoms of Promotes Metabolism, condition that causes substantial impairment to affected individuals. The nausea, headache and dehydration Detoxification & Immune Functions. dehydration of the body is caused by alcohol, which is a diuretic. Hangover is Spirulina characterized by the constellation of unpleasant physical and mental symptoms Supports the Management of Effectively eliminates acetaldehyde, Spirulina is a marine algal source that supports optimal health and wellness, due that occur after heavy alcohol drinking. the toxic by-product of alcohol to high concentration of essential nutrients. Spirulina is produced primarily from inflammation and allergies. two species of cyanobacteria: Arthrospira platensis and Arthrospira maxima. intake When alcohol is consumed, the liver breaks it down primarily into a toxic substance called acetaldehyde. The build up of acetaldehyde in the liver results Helps maintain healthy liver Spirulina is a microscopic, blue-green algal culture (a free floating filamentous cyanobacterium). Spirulina for dietary supplements is derived from Arthrospira in hangover symptoms such as headache, nausea, irritability and fatigue. functions platensis or Arthrospira maxima), Spirulina is a rich source of vegetable Accumulation of acetaldehyde at higher concentrations leads to the proteins, iron, pro-vitamin A carotenoids, vitamin B1 (thiamine), B2 (riboflavin), B3 development of physical symptoms of hangover, which include rapid pulse, (niacin), B6 (pyridoxine), B12 (cobalamin), vitamin C, vitamin D, vitamin E, folate, sweating, skin flushing, increased sensitivity to light and sound, redness of the vitamin K, biotin, pantothenic acid, beta carotene (source of vitamin A), inositol, eyes, muscle aches and thirst. The dehydrating effect of alcohol is also essential amino acids, and the rare essential fatty acid, GLA (gamma-linolenic responsible for morning dizziness, tiredness and general body weakness. acid). Liver Support is a unique formulation from Sami Direct that offers a holistic Studies show that Spirulina preparations have significant antioxidant activity, approach to the problems associated with alcohol dependency. It effectively benefit metabolism, detoxification, and immune functions; and support the maintains balance, manages stress, helps to sober down and deal with the management of inflammation and allergies. effects of hangover. Each Tablet contains: Each Capsule contains: Ingredient Quantity per Tablet Ingredient Quantity per Capsule 3 Spirulina 400 mg * Curcumin C Complex® 250 mg * BioPerine® 2.5 mg Fabenol® 90 mg *Patented – US & International Patents Vit B12 5 mcg Vit B6 1.5 mg Folic acid 100 mcg Suggested Use : Phyllanthus amarus 60 mg One tablet twice or thrice daily * BioPerine® 5 mg *Patented – US & International Patents Suggested Use : One capsule twice daily References: References: 1. Bharat B. Aggarwal Chapter 23 Curcumin Derived from Turmeric (Curcuma longa):a Spice for All Seasons. 1. Park, H.; Lee, Y.; Ryu, H.; Kim, M.; Chung, H.; Kim, W. (2008). "A randomized double-blind, placebo- Phytopharmaceuticals in Cancer Chemoprevention. © 2005 by CRC Press LLC. p 349-387. controlled study to establish the effects of spirulina in elderly Koreans". Annals of nutrition & metabolism 52 (4): 322–328. 2. S.Priya and PR Sudhakaran. Curcumin-induced recovery from hepatic injury involves induction of apoptosis of activated hepatic stellate cells. Indian. J. Biochem. Biophys. Vol 45, 2008; pp. 317-325. 2. Lu, H.K., Hsieh, C.C. Hsu, J.J., Yang, Y.K., & Chou, H.N. (2006). "Preventative effects of Spirulina platensis on skeletal muscle damage under exercise induced oxidative stress". European Journal of Applied 3. Chidi U. Igwe et al.,Assessment of the hepatic effects, phytochemical and proximate compositions of Physiology 98 (2): 220–226 Phyllanthus amarus African Journal of Biotechnology Vol. 6 (6), pp. 728-731, 19 March 2007. pp 728 – 731.
- 13. R3 Power™ Relief • Rebuild • Restore Optimum 1 ® ADVANCED JOINT SUPPORT FORMULA Blood Sugar Balance KEY BENEFITS KEY BENEFITS A joint is formed by the ends of two or more bones that are connected by thick Helps to overcome joint pains Optimum® 1 is a unique composition containing herbal extracts and nutrients Supports healthy blood sugar levels bands of tissue called ligaments. For example, the knee joint is formed by the that help to support healthy blood sugar level. Effectively reduces inflammation of Support the body’s natural ability to lower leg bone, called the tibia or shinbone, and the thighbone, called the femur. joints (arthritis) utilize insulin The hip joint is a ball-and-socket joint, formed by the ball, or femoral head, at the Blood sugar refers to the amount of glucose present in the blood. Normally, in upper end of the thighbone, and the rounded socket, or acetabulum, in the Prevents inflammation of the mammals the blood glucose level is maintained at a reference range between Effectively manages Impaired pelvis. tendons (tendonitis) about 3.6 and 5.8 mM (mmol/L) or 64.8 and 104.4 mg/dL. It is tightly regulated as Glucose Tolerance a part of metabolic homeostasis, by the hormone insulin. Impaired insulin Joint pain is a very common problem prevailing in almost every part of the world. secretion due to genetic or diet and lifestyle factors, or the inability to use insulin It is basically a symptom and not a disease and it has eventually become a part of i.e. insulin resistance encountered sometimes in obese individuals impact everybody’s life, especially aged people glucose homeostasis. Arthritis is a group of conditions involving damage to the joints of the body. The Failure to maintain blood glucose in the normal range leads to conditions of most common form, osteoarthritis (degenerative joint disease) is a result of persistently high (hyperglycemia) or low (hypoglycemia) blood sugar. Diabetes trauma to the joint, infection of the joint or age. mellitus, characterized by persistent hyperglycemia is the most prominent disease related to failure of blood sugar regulation. If left unchecked, can lead to Other arthritis forms are rheumatoid arthritis, psoriatic arthritis and autoimmune diseases in which the body attacks itself. Septic arthritis is caused a number of serious health problems including blindness, kidney disease, stroke by joint infection. Gout is another form of arthritis, caused by deposition of uric and heart disease. acid crystals in the joint, causing inflammation. Optimum®1 is a carefully formulated product from Sami Direct that contains 3 R Power™ is a sustained release composition containing herbal extracts and effective ingredients that support normal blood sugar levels, when combined nutrients that help support healthy joints and connective tissues in the body. with a healthy diet and lifestyle. Each Tablet contains: Each Tablet contains: Ingredient Quantity per Tablet Ingredient Quantity per Tablet Glucosamine HCl 750mg Momordicin® 100 mg **Boswellin® PS 100mg Chromium Picolinate 50 mcg * Curcumin C3 Complex® 100mg Silbinol® 100 mg * BioPerine® 5mg * BioPerine® 2.5 mg * Patented – US & International Patents *Patented – US & International Patents **Patent Pending Suggested Use : Suggested Use : One tablet twice daily One tablet twice daily Keep all su pplem ents ou t of re ach of childre n. References: 1. DiSilvestro, R, et al. Acute Absorption of Various Types of Chromium Supplement Complexes. Accepted for presentation at the Federation of American Societies for Experimental Biology (FASEB) annual meeting, San Diego, CA, April 4, 2005.. 2. Anderson, RA, et al. Lack of Toxicity of Chromium Chloride and chromium Picolinate in Rats. J Amer Coll Nut Vol. 16, No. 3 1997; 273-279. References: 3. Saifi, A.Q., Shinde, S., Kavishwar, W.K., and Gupta, S.R. (1971) Some aspects of phytochemistry and 1. Research Report – Sami Labs Limited. hypoglycaemic actions of Pterocarpus marsupium (Papilionaeceae). J. Res. Ind. Med., 6(2), 205-207.
- 14. Omega BioPlus ™ For Detoxification EFFECTIVELY REMOVES TOXINS KEY BENEFITS KEY BENEFITS It is a mistaken belief that in order to lose weight, one must eliminate fat from the It supports the liver and kidney The word “Detox” means detoxifying the body from toxins and other harmful Supports the body’s natural diet. On the contrary, eliminating fats from the diet totally can be very harmful to functions; and helps in maintaining chemicals and cleansing it for proper functioning and optimal health. mechanisms to eliminate toxins the body as good fats are essential to the body and play critical roles in n o r m a l b l o o d p re s s u re a n d metabolism and wellness. Body cleansing or detoxification helps rid the body of accumulated harmful Supports digestion cholesterol levels. substances, such as heavy metals and environmental toxins that exert a negative Essential fatty acids (EFAs) are beneficial fats chemically classified under It supports a healthy immune effect on the health of an individual. Supports the maintenance of polyunsaturated fatty acids (PUFA) that cannot be formed by the body and need system, and cardiovascular health normal liver functions to be supplied by the diet. The two primary EFAs are known as alpha-linolenic and wellness. There are two major approaches to the detoxification programme. acid (Omega-3) and linoleic acid (Omega-6). Omega-9 fatty acids (oleic acid) are 1. Antioxidant Support. Supports normal metabolic non-essential fatty acids, as they can be produced from the EFAs. However, It benefits in supporting Oxidation occurs at the cellular level, so detox must occur there as well. processes leading to sustained deficiency does occur when the diet is deficient in EFAs. cardiovascular health, joint health; Any deficiency of antioxidants in the diet causes problems associated with energy levels and stamina neuronal health and healthy skin, removal of toxins . Essential fatty acids are required for energy production in the body, cardiac hair and nails. function, health of hair, skin and nails, hormone production, brain function, and 2. Supporting healthy liver functions. for the integrity of the very structure of cells. Symptoms of omega-3 fatty acid A good detoxifying agent removes impurities from the blood through the liver. deficiency include extreme tiredness (fatigue), poor memory, dry skin, heart Liver is an important organ where toxins are processed so that they can be problems, mood swings or depression, and poor circulation. removed from the system. It is also responsible for detoxifying the body of poisonous substances by transforming and removing toxins and wastes. Omega BioPlus™ contains a vegetable derived omega 3, omega 6 and omega 9 fatty acids composition in a specific scientifically validated proportion to support SAMI DIRECT’s For Detoxification is a judicious blend of ingredients that can be healthy cell membranes and cellular functions, and attractive skin, hair and nails. used to provide these benefits. The ingredients have been chosen with care and The fatty acids composition is combined with sesame oil antioxidants and a formulated scientifically to offer a comprehensive and holistic support to the bioavailability enhancer derived from black pepper fruit. detoxification process. Each Softgel contains: Each Capsule contains: Ingredient Quantity per Softgel Ingredient Quantity per Capsule Omega 3 Fatty Acids 500 mg Peppermint oil 5 mg Sesamin Complex 10 mg FenuFibers® 100 mg * BioPerine® 5 mg Licorice extract 100 mg *Patented – US & International Patents Neem Leaf Extract 50 mg Picroliv® - 50 mg Apocynin 5% (Picrorhiza kurroa) LactoSpore® (15 mio) 10 mg Suggested Use : One softgel twice daily Suggested Use : One capsule daily upto 30 days. To be repeated after every 6 months. References: 1. Szapary, O. Philippe. The Heart Health Benefits of Omega-3 Fatty acids. Advanced Studies in Medicine. Vol 5 (6A); p-511-517. 2. Harbige L.S.; Layward L.; Morris-Downes M.M.; Dumonde D.C.; Amor S. The protective effects of omega- 6 fatty acids in experimental autoimmune encephalomyelitis (EAE) in relation to transforming growth factor-beta 1 (TGF-β1) up-regulation and increased prostaglandin E2 (PGE2) production. Clinical & Experimental Immunology, Volume 122, Number 3, December 2000, pp. 445-452(8). References: 3. Hirose, N et al. Inhibition of cholesterol absorption and synthesis in rats by sesamin. Journal of Lipid 1. Picrorhiza kurroa Monograph – Alternative Medicine Review, Volume 6, No.3, 2001, 319 – 321. Research Volume 32, 1991. P 629-638.