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CPR FOR ADULTS
1
2
Plan
4
 Definition/Aim of Cardiopulmonary Resuscitation (CPR)
 Treatment of VF / Pulseless VT
 Treatment of non-VF/VT rhythm
 Potential reversible causes of cardiac arrest
 Airway, IV Access, Drugs
Cardiopulmonary Resuscitation
(CPR) - Definition
5
Emergent medical applications that are performed for a living
whose respiratory and circulation functions have been stopped
in an immediate and unexpected status
6
To provide adequate amount of oxygenated blood
for vital organs
Cardiopulmonary Resuscitation
(CPR) - Aim
7
Cardiopulmonary Arrest (CPR)
8
Causes:
 Airway obstruction
 Respiratory distress
 Cardiac abnormalities
ACUTE MYOCARDIAL
INFARCTON
9
CPR – ILCOR (International Liaison Committee On Resuscitation)
 American Heart Association (AHA)
 European Resuscitation Council (ERC)
 Heart and Stroke Foundation of Canada (HSFC)
 Australian Resuscitation Council (ARC)
 Resuscitation Councils of Southern Africa (RCSA)
 Council of Latin America for Resuscitation (CLAR)
10
CPR
 Basic Life Support
 Advanced Life Support
 Prolonged Life Support
11
CPR
 Basic Life Support
 Advanced Life Support
 Prolonged Life Support
12
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/Pulseless VT)
Non-shockable
(PEA/Asystole)
1 Shock
150-360 J biphasic
or 360 J monophasic
Open Airway
Look for signs of life
Immediately resume
CPR 30:2
for 2 min
Call
Resuscitation
Team
During CPR:
• Correct reversible causes
• Check electrode position and
contact
• Attempt / verify:
IV access
airway and oxygen
• Give uninterrupted
compressions when airway
secure
• Give adrenaline every 3-5 min
• Consider: amiodarone,
atropine,
magnesium
Immediately resume
CPR 30:2
for 2 min
Adult ALS
Algorithm
13
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/Pulseless VT)
Non-shockable
(PEA/Asystole)
1 Shock
150-360 J biphasic
or 360 J monophasic
Open Airway
Look for signs of life
Immediately resume
CPR 30:2
for 2 min
Call
Resuscitation
Team
During CPR:
• Correct reversible causes
• Check electrode position and
contact
• Attempt / verify:
IV access
airway and oxygen
• Give uninterrupted
compressions when airway
secure
• Give adrenaline every 3-5 min
• Consider: amiodarone,
magnesium
Immediately resume
CPR 30:2
for 2 min
Adult ALS
Algorithm
14
Open Airway
Look for signs of life
…. to confirm cardiac arrest
 Patient response
 Open airway
 Check for normal breathing
(caution agonal breathing)
 Check circulation
 Monitoring
15
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/Pulseless VT)
Non-shockable
(PEA/Asystole)
1 Shock
150-360 J biphasic
or 360 J monophasic
Open Airway
Look for signs of life
Immediately resume
CPR 30:2
for 2 min
Call
Resuscitation
Team
During CPR:
• Correct reversible causes
• Check electrode position and
contact
• Attempt / verify:
IV access
airway and oxygen
• Give uninterrupted
compressions when airway
secure
• Give adrenaline every 3-5 min
• Consider: amiodarone,
magnesium
Immediately resume
CPR 30:2
for 2 min
Adult ALS
Algorithm
16
Open Airway
Look for signs of life
Call
Resuscitation
Team
Cardiac arrest confirmed
CPR 30:2
Until defibrillator /
monitor attached
17
Chest Compression
 30:2
 Compressions
 Centre of chest
 5-6 cm depth
 100-120 min-1
 Uninterrupted
compressions when
airway secured
 Avoid
 Provider fatigue
 Interruptions
18
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/Pulseless VT)
Non-shockable
(PEA/Asystole)
1 Shock
150-360 J biphasic
or 360 J monophasic
Open Airway
Look for signs of life
Immediately resume
CPR 30:2
for 2 min
Call
Resuscitation
Team
During CPR:
• Correct reversible causes
• Check electrode position and
contact
• Attempt / verify:
IV access
airway and oxygen
• Give uninterrupted
compressions when airway
secure
• Give adrenaline every 3-5 min
• Consider: amiodarone,
atropine,
magnesium
Immediately resume
CPR 30:2
for 2 min
Adult ALS
Algorithm
19
Adult ALS
Algorithm
Open Airway
Look for signs of life
Call
Resuscitation
Team
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/Pulseless VT)
Non-shockable
(PEA/Asystole)
20
Adult ALS
Algorithm
Open Airway
Look for signs of life
Call
Resuscitation
Team
CPR 30:2
Until defibrillator/monitor attached
Assess
Rhythm
Shockable
(VF/Pulseless VT)
Non-shockable
(PEA/Asystole)
CARDİAC ARREST RHYTHMS
1. Ventricular Fibrillation (VF)
2. Pulseless Ventricular Tachicardia (VF)
3. Asystole
4. Pulseless Electrical Activity (PEA)
21
Shockable (VF)
 Irregular waveform
 No recognisable QRS
complexes
 Random frequency and
amplitude
 Uncoordinated electrical activity
 Coarse /fine
 Exclude artifact
 movement
 electrical interference
Monomorphic VT
 broad complex rhythm
 rapid rate
 constant QRS morphology
Polymorphic VT
 torsade de pointes
Shockable (VT)
Precordial Thump
 Rapid treatment of a
witnessed and monitored
VF/VT cardiac arrest
 Used if defibrillator not
immediately available
?
1st shock
 150 - 200 J biphasic
 360 J monophasic
Assess
Rhythm
Shockable
(VF/Pulseless VT)
1 Shock
150-360 J biphasic
or 360 J monophasic
Immediately resume
CPR 30:2
for 2 min
Defibrillation Energies
 Vary with manufacturer
 Check local equipment
 If unsure, deliver 200 J (do not delay shock)
Deliver 2nd shock
Deliver 3rd shock
CPR for 2 min
If VF/VT persists
CPR for 2 min
Deliver 4th shock
Adrenalin, 1mg iV
Amiodaron, 300 mg
2nd and subsequent shocks
 Max. (270-360J) biphasic
 360 J monophasic
Minimise delays between CPR
and shocks (< 10 s)
After delivery of shock
Continue CPR for another 2 min
 stop CPR only if patient shows signs of life
After 2 min, assess rhythm:
If organised electrical activity, check for signs of life:
 if ROSC start post resuscitation care
 if no ROSC go to non VF/VT algorithm
If asystole, go to non VF/VT algorithm
Asystole
Pulseless Electrical
Activity (PEA)
Assess
Rhythm
Non-shockable
(PEA/Asystole)
Immediately resume
CPR 30:2
for 2 min
 Absent ventricular (QRS) activity
 Atrial activity (P waves) may persist
 Rarely a straight line trace
 Treat fine VF as asystole
Non-shockable
(Asystole)
Asystole
During CPR:
 check leads are attached
 adrenaline 1 mg IV every 3 – 5 min
 Clinical features of cardiac arrest
 ECG normally associated with an output
Non-shockable
(PEA)
Pulseless Electrical Activity
(PEA)
 Exclude/treat reversible causes
 Adrenaline 1 mg IV every 3-5 min
During CPR:
 Correct reversible causes
 Check electrode position and contact
 Attempt / verify:
- IV access
- Airway and oxygen
 Give uninterrupted compressions when airway
secure
 Give adrenaline every 3-5 min
 Consider: amiodarone, magnesium
Potential reversible causes:
 Hypoxia
 Hypovolaemia
 Hypo/hyperkalaemia & metabolic disorders
 Hypothermia
 Tension pneumothorax
 Tamponade, cardiac
 Toxins
 Thrombosis (coronary or pulmonary)
4H
4T
Airway and Ventilation
 Secure airway:
 tracheal tube
 supraglottic airway device
 e.g. LMA
 Once airway secured, if possible, do not
interrupt chest compressions for ventilation
 Avoid hyperventilation
Intravenous Access
 Peripheral versus central veins
Intraosseous Access
TRACHEAL ACCESS
x
Drugs
 Adrenaline
 Amiodarone
 Magnesium
 Thrombolytics
 Sodium bicarbonate
O2
Adrenaline
Actions:
 agonist arterial vasoconstriction
 systemic vascular resistance
 cerebral and coronary blood flow
 agonist  heart rate
 force of contraction
 myocardial O2 demand
(may increase ischaemia)
Adrenaline
Indications:
 During cardiac arrest
 VF/VT – give after 3rd shock
 Non VF/VT – give immediately
 Repeat every 3-5 min
 1 mg IV
 Cautious use after ROSC
Amiodarone
Actions:
 Lengthens duration of action potential
 Prolongs QT interval
 Mild negative inotrope - may cause
hypotension
Amiodarone
Indications:
 Shock refractory VF/VT
 300 mg IV
 Give after 3rd shock
 If unavailable give lidocaine 1.5mg/kg IV
Atropine
Actions:
 Blocks effects of vagus nerve
 Increases sinus node automaticity
 Increases atrioventricular conduction
Atropine
Indications:
 Peri-arrest
 Symptomatic sinus, atrial or nodal bradycardia
 500 mcg IV increments to 3 mg
Magnesium
 Hypomagnesaemia often co-exists with
hypokalaemia
Actions:
 Depresses neurological and myocardial
function
 A physiological calcium blocker
Magnesium
Indications:
 VF / VT with hypomagnesaemia
 Torsade de pointes
 Atrial fibrillation
 Digoxin toxicity
 Dose:
 cardiac arrest 2 g (8 mmol) IV bolus
 peri-arrest 2 g (8 mmol) IV over 10 min
Thrombolytic Drugs
Actions:
 Dissolves thrombus
 Improves cerebral blood flow
 Has a role in coronary thrombosis and
pulmonary embolism
Thrombolytic Drugs
Indications:
 Cardiac arrest caused by suspected pulmonary
embolus
 Can take up to 60 min to have effect
 Dose:
 Tenecteplase 500-600 mcg kg-1 IV over 10 sec
 Alteplase (rt-PA) 10 mg IV over 1-2 min followed
by IV infusion of 90 mg over 2 h
Sodium Bicarbonate
Actions:
 Alkalinising agent (increases pH)
 But can:
 increase carbon dioxide load
 inhibit release of oxygen to tissues
 impair myocardial contractility
 cause hypernatraemia
Sodium Bicarbonate
Indications:
 Life-threatening hyperkalaemia
 Tricyclic overdose
 Severe metabolic acidosis (pH < 7.1)
 Dose:
 50 ml 8.4% sodium bicarbonate IV
Summary
• ALS algorhythm provides a standardised approach to
cardiac arrest treatment
• Shockable rhythms (VF/pulseless VT)
• Non-shockable rhythms (Asystole, PEA)
• Reversible reasons of cardiac arrest (4H,4T)
LAST WORDS
Drugs role in cardiac arrest becomes after
effective chest compression, effective ventilation
with high oxygen concentration and defibrillation
53
THANK
YOU…
Dr. Sule AKIN
54
THANK
YOU…
Dr. Sule AKIN

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Cpr for adults

  • 2. 2
  • 3.
  • 4. Plan 4  Definition/Aim of Cardiopulmonary Resuscitation (CPR)  Treatment of VF / Pulseless VT  Treatment of non-VF/VT rhythm  Potential reversible causes of cardiac arrest  Airway, IV Access, Drugs
  • 5. Cardiopulmonary Resuscitation (CPR) - Definition 5 Emergent medical applications that are performed for a living whose respiratory and circulation functions have been stopped in an immediate and unexpected status
  • 6. 6 To provide adequate amount of oxygenated blood for vital organs Cardiopulmonary Resuscitation (CPR) - Aim
  • 7. 7
  • 8. Cardiopulmonary Arrest (CPR) 8 Causes:  Airway obstruction  Respiratory distress  Cardiac abnormalities ACUTE MYOCARDIAL INFARCTON
  • 9. 9 CPR – ILCOR (International Liaison Committee On Resuscitation)  American Heart Association (AHA)  European Resuscitation Council (ERC)  Heart and Stroke Foundation of Canada (HSFC)  Australian Resuscitation Council (ARC)  Resuscitation Councils of Southern Africa (RCSA)  Council of Latin America for Resuscitation (CLAR)
  • 10. 10 CPR  Basic Life Support  Advanced Life Support  Prolonged Life Support
  • 11. 11 CPR  Basic Life Support  Advanced Life Support  Prolonged Life Support
  • 12. 12 CPR 30:2 Until defibrillator/monitor attached Assess Rhythm Shockable (VF/Pulseless VT) Non-shockable (PEA/Asystole) 1 Shock 150-360 J biphasic or 360 J monophasic Open Airway Look for signs of life Immediately resume CPR 30:2 for 2 min Call Resuscitation Team During CPR: • Correct reversible causes • Check electrode position and contact • Attempt / verify: IV access airway and oxygen • Give uninterrupted compressions when airway secure • Give adrenaline every 3-5 min • Consider: amiodarone, atropine, magnesium Immediately resume CPR 30:2 for 2 min Adult ALS Algorithm
  • 13. 13 CPR 30:2 Until defibrillator/monitor attached Assess Rhythm Shockable (VF/Pulseless VT) Non-shockable (PEA/Asystole) 1 Shock 150-360 J biphasic or 360 J monophasic Open Airway Look for signs of life Immediately resume CPR 30:2 for 2 min Call Resuscitation Team During CPR: • Correct reversible causes • Check electrode position and contact • Attempt / verify: IV access airway and oxygen • Give uninterrupted compressions when airway secure • Give adrenaline every 3-5 min • Consider: amiodarone, magnesium Immediately resume CPR 30:2 for 2 min Adult ALS Algorithm
  • 14. 14 Open Airway Look for signs of life …. to confirm cardiac arrest  Patient response  Open airway  Check for normal breathing (caution agonal breathing)  Check circulation  Monitoring
  • 15. 15 CPR 30:2 Until defibrillator/monitor attached Assess Rhythm Shockable (VF/Pulseless VT) Non-shockable (PEA/Asystole) 1 Shock 150-360 J biphasic or 360 J monophasic Open Airway Look for signs of life Immediately resume CPR 30:2 for 2 min Call Resuscitation Team During CPR: • Correct reversible causes • Check electrode position and contact • Attempt / verify: IV access airway and oxygen • Give uninterrupted compressions when airway secure • Give adrenaline every 3-5 min • Consider: amiodarone, magnesium Immediately resume CPR 30:2 for 2 min Adult ALS Algorithm
  • 16. 16 Open Airway Look for signs of life Call Resuscitation Team Cardiac arrest confirmed CPR 30:2 Until defibrillator / monitor attached
  • 17. 17 Chest Compression  30:2  Compressions  Centre of chest  5-6 cm depth  100-120 min-1  Uninterrupted compressions when airway secured  Avoid  Provider fatigue  Interruptions
  • 18. 18 CPR 30:2 Until defibrillator/monitor attached Assess Rhythm Shockable (VF/Pulseless VT) Non-shockable (PEA/Asystole) 1 Shock 150-360 J biphasic or 360 J monophasic Open Airway Look for signs of life Immediately resume CPR 30:2 for 2 min Call Resuscitation Team During CPR: • Correct reversible causes • Check electrode position and contact • Attempt / verify: IV access airway and oxygen • Give uninterrupted compressions when airway secure • Give adrenaline every 3-5 min • Consider: amiodarone, atropine, magnesium Immediately resume CPR 30:2 for 2 min Adult ALS Algorithm
  • 19. 19 Adult ALS Algorithm Open Airway Look for signs of life Call Resuscitation Team CPR 30:2 Until defibrillator/monitor attached Assess Rhythm Shockable (VF/Pulseless VT) Non-shockable (PEA/Asystole)
  • 20. 20 Adult ALS Algorithm Open Airway Look for signs of life Call Resuscitation Team CPR 30:2 Until defibrillator/monitor attached Assess Rhythm Shockable (VF/Pulseless VT) Non-shockable (PEA/Asystole) CARDİAC ARREST RHYTHMS 1. Ventricular Fibrillation (VF) 2. Pulseless Ventricular Tachicardia (VF) 3. Asystole 4. Pulseless Electrical Activity (PEA)
  • 21. 21 Shockable (VF)  Irregular waveform  No recognisable QRS complexes  Random frequency and amplitude  Uncoordinated electrical activity  Coarse /fine  Exclude artifact  movement  electrical interference
  • 22. Monomorphic VT  broad complex rhythm  rapid rate  constant QRS morphology Polymorphic VT  torsade de pointes Shockable (VT)
  • 23. Precordial Thump  Rapid treatment of a witnessed and monitored VF/VT cardiac arrest  Used if defibrillator not immediately available ?
  • 24. 1st shock  150 - 200 J biphasic  360 J monophasic Assess Rhythm Shockable (VF/Pulseless VT) 1 Shock 150-360 J biphasic or 360 J monophasic Immediately resume CPR 30:2 for 2 min
  • 25. Defibrillation Energies  Vary with manufacturer  Check local equipment  If unsure, deliver 200 J (do not delay shock)
  • 26. Deliver 2nd shock Deliver 3rd shock CPR for 2 min If VF/VT persists CPR for 2 min Deliver 4th shock Adrenalin, 1mg iV Amiodaron, 300 mg 2nd and subsequent shocks  Max. (270-360J) biphasic  360 J monophasic Minimise delays between CPR and shocks (< 10 s)
  • 27. After delivery of shock Continue CPR for another 2 min  stop CPR only if patient shows signs of life After 2 min, assess rhythm: If organised electrical activity, check for signs of life:  if ROSC start post resuscitation care  if no ROSC go to non VF/VT algorithm If asystole, go to non VF/VT algorithm
  • 29.  Absent ventricular (QRS) activity  Atrial activity (P waves) may persist  Rarely a straight line trace  Treat fine VF as asystole Non-shockable (Asystole)
  • 30. Asystole During CPR:  check leads are attached  adrenaline 1 mg IV every 3 – 5 min
  • 31.  Clinical features of cardiac arrest  ECG normally associated with an output Non-shockable (PEA)
  • 32. Pulseless Electrical Activity (PEA)  Exclude/treat reversible causes  Adrenaline 1 mg IV every 3-5 min
  • 33. During CPR:  Correct reversible causes  Check electrode position and contact  Attempt / verify: - IV access - Airway and oxygen  Give uninterrupted compressions when airway secure  Give adrenaline every 3-5 min  Consider: amiodarone, magnesium
  • 34. Potential reversible causes:  Hypoxia  Hypovolaemia  Hypo/hyperkalaemia & metabolic disorders  Hypothermia  Tension pneumothorax  Tamponade, cardiac  Toxins  Thrombosis (coronary or pulmonary) 4H 4T
  • 35. Airway and Ventilation  Secure airway:  tracheal tube  supraglottic airway device  e.g. LMA  Once airway secured, if possible, do not interrupt chest compressions for ventilation  Avoid hyperventilation
  • 36. Intravenous Access  Peripheral versus central veins
  • 38. Drugs  Adrenaline  Amiodarone  Magnesium  Thrombolytics  Sodium bicarbonate O2
  • 39. Adrenaline Actions:  agonist arterial vasoconstriction  systemic vascular resistance  cerebral and coronary blood flow  agonist  heart rate  force of contraction  myocardial O2 demand (may increase ischaemia)
  • 40. Adrenaline Indications:  During cardiac arrest  VF/VT – give after 3rd shock  Non VF/VT – give immediately  Repeat every 3-5 min  1 mg IV  Cautious use after ROSC
  • 41. Amiodarone Actions:  Lengthens duration of action potential  Prolongs QT interval  Mild negative inotrope - may cause hypotension
  • 42. Amiodarone Indications:  Shock refractory VF/VT  300 mg IV  Give after 3rd shock  If unavailable give lidocaine 1.5mg/kg IV
  • 43. Atropine Actions:  Blocks effects of vagus nerve  Increases sinus node automaticity  Increases atrioventricular conduction
  • 44. Atropine Indications:  Peri-arrest  Symptomatic sinus, atrial or nodal bradycardia  500 mcg IV increments to 3 mg
  • 45. Magnesium  Hypomagnesaemia often co-exists with hypokalaemia Actions:  Depresses neurological and myocardial function  A physiological calcium blocker
  • 46. Magnesium Indications:  VF / VT with hypomagnesaemia  Torsade de pointes  Atrial fibrillation  Digoxin toxicity  Dose:  cardiac arrest 2 g (8 mmol) IV bolus  peri-arrest 2 g (8 mmol) IV over 10 min
  • 47. Thrombolytic Drugs Actions:  Dissolves thrombus  Improves cerebral blood flow  Has a role in coronary thrombosis and pulmonary embolism
  • 48. Thrombolytic Drugs Indications:  Cardiac arrest caused by suspected pulmonary embolus  Can take up to 60 min to have effect  Dose:  Tenecteplase 500-600 mcg kg-1 IV over 10 sec  Alteplase (rt-PA) 10 mg IV over 1-2 min followed by IV infusion of 90 mg over 2 h
  • 49. Sodium Bicarbonate Actions:  Alkalinising agent (increases pH)  But can:  increase carbon dioxide load  inhibit release of oxygen to tissues  impair myocardial contractility  cause hypernatraemia
  • 50. Sodium Bicarbonate Indications:  Life-threatening hyperkalaemia  Tricyclic overdose  Severe metabolic acidosis (pH < 7.1)  Dose:  50 ml 8.4% sodium bicarbonate IV
  • 51. Summary • ALS algorhythm provides a standardised approach to cardiac arrest treatment • Shockable rhythms (VF/pulseless VT) • Non-shockable rhythms (Asystole, PEA) • Reversible reasons of cardiac arrest (4H,4T)
  • 52. LAST WORDS Drugs role in cardiac arrest becomes after effective chest compression, effective ventilation with high oxygen concentration and defibrillation