Greetings from Genotypic Technology, Bangalore (www.genotypic.co.in). We are a 13 year old genomics and bioinformatics company ( 65+ employees, Service. Products and R & D) based in Bangalore, India, primarily working on applications of Microarrays and Next Generation Sequencing in Human Health and Disease, including in Molecular Diagnostics, Prognosis, Therapeutics, Vaccine Research, Basic Science Research, Veterinary Science, Agriculture, Industrial Biotechnology, Microbial Genetics and more. Our major strength is in customized genomics solutions, particularly in your field, we can develop panel of markers for specific diseases, optimize, validate and help commercialize on open platforms or specific instrument platforms- in microarrays and sequencing based methods/ assays. We can also use genomic markers to aid in treatment of specific disease using personalized medicine approaches. All this can be done on a comprehensive end-to-end manner in our company as we have a very good blend of molecular biology and bioinformatics with totally 6 Ph.Ds. We work closely with Agilent's R &D as their partner.

2. Pioneered Microarrays and Next Generation Sequencing Services.

3. Well equipped with cutting edge technologies to handle large scale genomics projects.

4. Our core strength is customization and new application development.

5. Team Genotypic has 8 PhDs and more than 60 Masters.

6. Teams: qPCR & Molecular biology lab, Certified Microarray Lab, NGS lab, Array Design informatics, Microarray Analysis, NGS Analysis.

7. With 2 GAIIx sequencers we specialize in long reads >140 base paired end short turnaround times

8. We specialize in custom arrays and non standard applicationFollow us Largest NGS and Microarray Group in Linkedin – managed by Genotypic www.linkedin.com/groups?about=&gid=1907871&trk=anet_ug_grppro Plant breeding & Genetics AND Agri Genomics www.linkedin.com/groups?mostPopular=&gid=3186656 Released on 1st March 2011 ISO 9001:2008 Certified Laboratory

10. Cancer genomics

11. miRNAprofiling and small RNAs

12. Plant / AgriGenomics

13. Alternative Splice Variants

14. Bovine / Cattle Genomics

15. ChIP on chip & DNA Methylation

16. Toxicogenomics / Clinical genomics

17. aCGH (Comparative Genomics)

18. Biomarker Discovery / Epigenetics

19. CNV(Copy Number Variations)

20. Bacterial Biosensors

21. SNP Validation Arrays

22. Drug re-purposing/ Drug target discovery

23. InDELs (Insertions & Deletions)4x 44K format 4x 180K format 1 x 244K format 1 x 1M format 2 x 105K format 2 x 400K format - New High resolution scanning and automated feature extraction with guaranteed high quality results Custom Design Arrays Any organism, Any sequence, Any application NO SETUP FEES! NO MINIMUM ORDER! Statistical analysis Biological analysis High quality RNA / DNA extraction and quality control Have an Idea? Talk to us! We have the right solution and technology to translate your ideas into results! Write to us at genomics@genotypic.co.in Ready to use arrays available for most bacteria, fungi, lower eukaryotes, insects, fish, plants, mammals and many more… www.genotypic.co.in/micro_arrays.html Catalog OR Custom microarray slide

25. Extremely High throughput- Sequence 100s of bacterial, small organism genomes

26. Sequence complete human genome in a week

27. DNA, RNA Sequencing of organisms with little or no reference information available

29. Targeted Re-sequencing

30. SNP, Mutation identification

31. Transcriptome sequencing

32. Digital gene expression

33. ChIP sequencing

34. Methylome sequencing

36. Human Genetics- Disease Inheritance studies

37. Transcriptome/RNA sequencing

38. Metagenomics

39. Agrigenomics

40. Pathogen detection in host system

42. Sequence selected genes / genomic regions in multiple samples combined with DNA Capture using Agilent SureSelect Technology - On-Array DNA Capture and In-Solution (Liquid) Capture

43. Sample/ Library preparation, Multiplexing

44. Compatible with all NGS platforms.List of Genes, Exons, Genomic regions/ Choose from catalog DNA Capture designs Baits Insolution Capture Microarray Genomic DNA Hybridization Elution of Captured Material Fragmentation (Sonication / Shearing) Enrichment by qPCR Repair ends Captured DNA ready for Shearing Ligate adapters At Genotypic we have successfully completed more than 200 NGS projects resulting in > 20 publications.

45. QC, UNDERSTAND, ANALYSE, INTERPERT, APPLY Efficient Analysis of High Throughput Genomics Data “Any platform, Any format, Any application” “Align  Assemble  Annotate  Analyze” MICROARRAY DATA ANALYSIS COMPREHENSIVE NGS DATA ANALYSIS Genotypic Technology provides the complete microarray data analysis services for Gene expression data generated using any platform. The end-point of analysis includes Biological interpretation of differentially regulated genes into significant functional categories and pathways. Our Reports Include publication quality charts and graphs. Sequence Data (Reads) Reference Sequence (Optional) QC on Reference QC on Reads PRELIMINARY DATA ANALYSIS SERVICE QC Report of reads and reference sequences (Min/Max/Median Read Length, No. & % of HQ Reads, No. & % of HQ Bases, No. & % of NON ATGC Bases) Start Point: Raw Data (.txt, .cel files accepted) Deliverables : QC reports, List of differentially regulated genes/ Enriched probes with detailed annotation. Significant Gene ontology categories with p-value, Significant pathways regulated with p-value. Time taken – 3 Days Alignment Statistics (% Coverage, % of mapped and unmapped reads, Avg. Read Depth, No. & Length of Gaps, Avg. Gap Length) CUSTOM DATA ANALYSIS SERVICE Start Point : RawData (.txt, .cel files accepted) Deliverables: Image QC, Raw Data QC, Raw Data, Differentials / Enriched probes with detailed annotation, Significant Gene ontology categories with p-value, Significant pathways regulated with p-value, spreadsheet with gene vs client requested key words with publication evidences. Time taken – 5 Days De Novo Genome assembly Small RNA Assembly 15th April 2011 Variation Analysis BIOLOGICAL ANALYSIS SERVICE ChIPseq Analysis Start Point : Gene list & Keywords Deliverables: Literature curated gene Vs keyword relationship. Time taken – 5 Days Transcriptome Analysis Simple Desktop Application for Rapid Quality Control and Reporting of NGS Data and Processed Sequence Files www.genotypic.co.in/SeqQC.html Project Planning till Publication Quality Reports, End to End NGS and MICROARRAY services at Genotypic NGS – Microarray Lab / Analysis Training / Workshops www.nextgenseq.com/register Tools for interpretation of Data www.genotypic.co.in/products.html Genotypic’sclientele, collaborators include Indian Institute of Science, UNILEVER, Astra Zenca, Evogene, JNU, IMTECH, Biocon, WiezmannInstitue, Quark Pharma, Novartis, Harvard University… Genotypic Technology Pvt. Ltd. #259, Apurva, RMV 2nd Stage, 80 Feet Road, Bangalore – 560094, India Ph: +91-80-40538200 Fax: +91-80-40538222,USA Phone: +1-(215) 253 4495 Website: www.genotypic.co.in, E-mail: genomics@genotypic.co.in