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1.
FIGURE 5- 1 Exposure
routes for chemical agents in hazardous waste.
2.
FIGURE 5-2 Overview of
absorption, distribution, storage, transformation, and elimination of a toxic substance in the human body.
3.
FIGURE 5-3 Types of
doses for dermal contact with contaminated soil.
4.
FIGURE 5-4 Correlation of
atmospheric benzene concentrations with urinary phenol levels in workers in a rubber coating plant.
5.
FIGURE 5-5 Effect of
dose fractionalization on accumulation of a toxic compound.
6.
FIGURE 5-6 Sequence of
events leading up to a toxic response.
7.
FIGURE 5-7 Representative cellular
targets for toxic action.
8.
FIGURE 5-8 Lock-and-key model
for toxic action.
9.
FIGURE 5-9 Example of
compounds with identical molecular formula but different toxicity.
10.
FIGURE 5-10 Inhibition of
enzyme acetylcholinesterase (AChE) by organophosphorus.
11.
FIGURE 5-11 Dose-response relationship
(dose versus mortality).
12.
FIGURE 5-12 Dose-response relationship
for erythrocyte protoporphyrin (EP) in blood as a function of the blood lead level in subpopulations.
13.
FIGURE 5-13 Effect of
EGM on the relative organ weights of testes and prostate.
14.
FIGURE 5-14 Health effects
from breathing and/or ingesting lead.
15.
FIGURE 5-15 Health effects from
breathing benzene.
16.
FIGURE 5-16 Adequacy of
human exposure data on health effects of benzene.
17.
FIGURE 5-17 Adequacy of
animal test data on health effects of benzene.
18.
FIGURE 5-18 Location of
NOAEL and LOAEL doses with respect to the threshold on a typical dose- response curve.
19.
FIGURE 5-19 Three stages
in carcinogenesis.
20.
FIGURE 5-20 Metabolic activation
of benzo(a)pyrene.
21.
FIGURE 5-21 Example of
a point mutation through base pair substitution.
22.
FIGURE 5-22 2,3,7,8- tetrachlorodibenzo(p)dioxin.
23.
FIGURE 5-23 Hypothetical dose- response
curve for a typical complete carcinogen.
24.
FIGURE 5-24 Extrapolation of
dose- response relationship for liver tumors induced by 2- cetylaminofluorene in the low-dose range.
25.
FIGURE 5-25 Toxicological/ecological relevance and
time scale of toxic responses for levels of biological organization.
26.
FIGURE 5-26 Idealized plot
of dose-response relationship.
27.
FIGURE 5-27 Graphical interpolation of
time- ependent LC50 values for sodium selenite.
28.
FIGURE 5-28 Biomagnification of
pesticides in aquatic food chains.
29.
FIGURE 5-29 Possible movement
and fate of a contaminant after absorption into the bloodstream of fish.
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