2. “We value life,
we provide natural heart health”
Steven Härting
CEO, Nutrartis S.A.

3. The chasm: from sterols to end-products
 $200 B Market
 Health benefit
 High house hold
penetration (EU)
 Proven to lower
cholesterol
 Limited supply
 Formulation/logistics
/regulatory hurdles
 Fat content
 Limited food
categories

4. Market access made simple
 Largest worldwide
 Non GMO
 Pure pine tree sterols
 Commited to plant sterol
innovation
 Sub-micron dispersible
sterols
 $200 B Market
 Health benefit
 High house hold
penetration (EU)

5. plant sisters of cholesterol
Phytostannols are hydrogenated sterols
Known and used to decrease LDLc
Phytosterols are

6. Versatile and easy to use
(Can go into any food category without
affecting taste)
Clinically proven
(Lowers LDL cholesterol and
triglycerides)
FAT / ALERGEN / GMO FREE
FREE DISPERSIBLE STEROLS
Our products

7. 1998: Esterified phytosterols
• Low melting point (60ºC).
• Soluble in lipid matrices.
• Incorporates a fatty acid (rancidity,
• higher energy intake).
• Requires esterase activity in the intestine.
2003: Dispersible free phytosterols
• Fat free and dispersible in water.
• Big size particles, precipitate.
• Difficult to incorporate into food matrices .
• Low cholesterol reduction efficiency.
• 95% of the market
• 85% Margarines
• <5% of the market
Phytosterols on the market

8. ANNEX
Other sterol ingredients
• Sterol esters
40% fatty acids, easily oxidized, limited applicability
• Other dispersible sterols:
Uncertain clinical effect, decanting, gritty

9. Diameter 50.0 1
Surface factor 1 2,500
NUTRARTIS Phytosterols

10. N16 – particle size distribution

11. N16 Sub-micron 16% sterol liquid dispersion (available today)
P80 80% sterol powder (available today)
N25 Concentrated version of N16 (available 1st quarter 2015)
PX Powder for direct comsumption (available 2nd quarter 2015)
(THROUGH PROPRIETARY TECHNOLOGY)
Our products

12. Applications
Soft drinks
Juice and juice drinks
Iced tea and coffe
Mixes
Dairy
Cheese
Creamers
Dairy alternatives
Yogurt
Milk
Spreads
Bakery
Biscuits
Bread
Cakes
Mixes
Supplements
Liquid sachet
Powder sachet
Tablets and softgels
Cereals
Breakfast cereals
Energy and cereal barsOther
Sauces and dressings
Ready meals
Desserts
And more!

13. Nutrartis clinical study
56 pubs in PubMed (Mar15) starting in 2008, mostly all PS
THE food centre together with Maastricht

14. References:
Amir Shaghaghi, J.Funct.Food 2014, 280; Balk, , Atherosclerosis 2006, 19 ; Othman, Nut.Rev. 2011, 299
-30
-25
-20
-15
-10
-5
0
5
10
Nutrartis sterols Sterol esters Omega-3 Glucans
Clinical benchmark
Triglycerides
HDL
Cholesterol
LDL
Cholesterol
Total
Cholesterol
HDL : Total
Cholesterol
Ratio

15. Mechanism of action PS

16. 1. A technically and clinically superior product
2. Simpler handling, new product development and processes
3. Assured supply of raw material through Arboris LLC
4. Technical, formulation and regulatory support
5. Technology licensing for cost-effective manufacturing
What we offer:

18. ANNEX
Labeling guidelines (general)
• Chile: Food labeling must comply with the technical rules on nutritional
guidelines according to Resolución Exenta N° 764/09.
• Brazil: Foods must be registered in the category of “Alimentos com
Alegações de Propriedade Funcional e ou de Saúde” and their efficacy
proven according to regulations 18/99 and 19/99.
• European Union: Food labeling must comply with Commission Regulation
(EC) No 608/2004.
• United States: Food labeling must comply with Regulation 21 CFR 101.83.

19. ANNEX
FOOD CATEGORY Liquid Powder
Bakery
Biscuits
Bread
Cakes
Mixes
Cereals
Breakfast cereals
Energy bars
Supplements
Sachets
Tablets and softgels
Other
FOOD CATEGORY Liquid Powder
Soft drinks
Juice and juice drinks
Iced tea and coffee
Mixes
Dairy
Cheese
Creamers
Dairy alternative
Yogurt
Milk
Spreads
Product / application