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Julie	
  Spero,	
  MBA,	
  NC	
   	
   1	
  of	
  15	
  
	
  
	
  
	
  
Advance	
  Protein	
  Powder	
  Nutritional	
  Report	
  
	
  
	
  
	
  
	
  Julie	
  Spero,	
  MBA,	
  NC	
  
	
  President,	
  National	
  Association	
  of	
  Nutrition	
  Professionals	
  
	
  
18	
  May	
  2014	
  
	
  
Overview:	
  
	
  
Advance	
  Protein	
  Powder	
  (APP)	
  is	
  a	
  high	
  quality,	
  organically	
  derived,	
  wild	
  marine-­‐based	
  
protein	
  powder,	
  which	
  is	
  highly	
  stable	
  with	
  a	
  shelf	
  life	
  of	
  over	
  5	
  years.	
  	
  It	
  is	
  virtually	
  odorless	
  
and	
  tasteless	
  with	
  high	
  levels	
  of	
  naturally	
  occurring	
  organic	
  minerals	
  giving	
  it	
  a	
  nutritional	
  
profile	
  superior	
  to	
  other	
  protein	
  powders	
  on	
  the	
  market.	
  	
  APP	
  is	
  made	
  using	
  a	
  patent-­‐
pending	
  manufacturing	
  process	
  that	
  is	
  both	
  green	
  and	
  sustainable.	
  	
  It	
  is	
  non-­‐hygroscopic	
  and	
  
very	
  moisture	
  resistant,	
  contributing	
  to	
  its	
  long	
  shelf	
  life.	
  	
  This	
  report	
  presents	
  an	
  overview	
  of	
  
the	
  health	
  benefits	
  of	
  the	
  all	
  natural	
  Advance	
  Protein	
  Powder	
  comparing	
  it	
  with	
  BlueWave,	
  
another	
  fish	
  protein	
  product	
  on	
  the	
  market	
  and	
  also	
  with	
  several	
  examples	
  from	
  the	
  two	
  
most	
  common	
  protein	
  supplement	
  categories	
  available:	
  whey	
  and	
  soy.	
  
	
  
	
  
	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   2	
  of	
  15	
  
About	
  Whey	
  protein	
  powder	
  
	
  
Whey	
  used	
  to	
  be	
  considered	
  a	
  dairy	
  industry	
  waste	
  product.	
  Whey	
  is	
  what	
  remains	
  after	
  the	
  
butter,	
  cream,	
  milk	
  is	
  drawn	
  off	
  and	
  the	
  cheese	
  has	
  been	
  made.	
  The	
  dairy	
  industry	
  long	
  
considered	
  whey	
  a	
  problem	
  because	
  dumping	
  it	
  into	
  sewer	
  systems	
  or	
  feeding	
  it	
  to	
  pigs	
  cost	
  
as	
  much	
  or	
  slightly	
  more	
  than	
  the	
  value	
  of	
  the	
  whey	
  as	
  a	
  commodity.	
  This	
  problem	
  was	
  
solved	
  when	
  manufacturers	
  developed	
  techniques	
  for	
  drying	
  the	
  whey	
  at	
  high	
  temperatures	
  
and	
  putting	
  the	
  powders	
  into	
  body	
  building	
  powders,	
  high	
  protein	
  bars	
  and	
  other	
  food	
  
products.i
	
  
	
  
While	
  there	
  are	
  some	
  high	
  quality	
  whey	
  protein	
  powders	
  available,	
  many	
  more	
  are	
  of	
  
marginal	
  or	
  poor	
  quality.	
   The	
  most	
  expensive	
  and	
  better	
  quality	
  products	
  are	
  made	
  from	
  
organic	
  milk	
  and	
  processed	
  at	
  low	
  temperatures	
  to	
  preserve	
  the	
  maximum	
  amino	
  acid	
  
content	
  potential	
  and	
  maintain	
  a	
  full	
  range	
  of	
  important	
  protein	
  components	
  such	
  as	
  
immunoglobulins	
  and	
  serum	
  albumin	
  (which	
  are	
  also	
  present	
  in	
  APP	
  fish	
  protein).	
   The	
  quality	
  
of	
  other	
  whey	
  protein	
  powders	
  can	
  vary	
  widely	
  depending	
  on	
  the	
  source	
  of	
  the	
  milk	
  used	
  as	
  
well	
  as	
  the	
  various	
  steps	
  in	
  processing.	
  	
   Commercial	
  milk	
  often	
  contains	
  growth	
  hormone	
  
(rBGH)	
  and	
  a	
  number	
  of	
  antibiotics;	
  the	
  FDA	
  has	
  approved	
  thirty.	
   An	
  estimated	
  sixty	
  percent	
  
of	
  herbicides	
  used	
  in	
  the	
  U.S.	
  as	
  well	
  as	
  pesticides	
  and	
  other	
  petrochemicals	
  are	
  applied	
  to	
  
produce	
  higher	
  yields	
  of	
  feed	
  crops	
  that	
  are	
  eaten	
  by	
  commercial	
  dairy	
  cows	
  and	
  are	
  present	
  
in	
  the	
  milk	
  they	
  produce.	
   As	
  you	
  can	
  see,	
  the	
  quality	
  of	
  the	
  whey	
  can	
  only	
  be	
  as	
  good	
  as	
  the	
  
quality	
  of	
  the	
  food,	
  nutrition	
  and	
  care	
  given	
  to	
  the	
  cows.	
  
	
  
The	
  Whey	
  protein	
  products	
  chosen	
  for	
  this	
  comparison	
  represent	
  products	
  that	
  are	
  available	
  
for	
  purchase	
  in	
  bulk	
  or	
  commonly	
  used	
  in	
  protein	
  drinks	
  and	
  bars.	
  	
  They	
  include	
  an	
  organic	
  
whey	
  protein	
  product	
  from	
  Source	
  Organic	
  who	
  declare	
  their	
  cows	
  have	
  never	
  been	
  given	
  
hormones,	
  antibiotics,	
  steroids,	
  or	
  genetically	
  modified	
  feed	
  (GMO).	
  The	
  others	
  are	
  plain	
  
protein	
  products	
  with	
  no	
  flavoring	
  added.	
  	
  Whey	
  protein	
  (of	
  good	
  quality)	
  is	
  one	
  of	
  the	
  most	
  
bio-­‐available	
  sources	
  of	
  supplemental	
  protein	
  available	
  at	
  96-­‐98%.	
   As	
  mentioned,	
  the	
  quality	
  
can	
  vary	
  considerably	
  depending	
  on	
  the	
  milk	
  source	
  and	
  the	
  methods	
  used	
  in	
  processing.	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   3	
  of	
  15	
  
	
  
• Source	
  Organic	
  Whey	
  protein	
  is	
  processed	
  using	
  low	
  temperature	
  drying	
  and	
  filtration	
  
and	
  therefore	
  retains	
  immune	
  components	
  as	
  well	
  as	
  glutathione.	
  
	
  
• American	
  whey	
  protein	
  is	
  unflavored,	
  however	
  it	
  does	
  contains	
  xanthan	
  gum	
  	
  
• Both	
  American	
  Whey	
  and	
  NutriBio	
  are	
  whey	
  protein	
  isolates	
  with	
  protein	
  levels	
  at	
  
around	
  90%.	
  
	
  
About	
  Soy	
  protein	
  powder	
  
	
  
The	
  Solae	
  Company,	
  owned	
  by	
  DuPont,	
  is	
  a	
  leader	
  in	
  developing	
  soy	
  products	
  and	
  ingredients	
  
for	
  food.	
   On	
  their	
  website	
  they	
  tout	
  the	
  healthy	
  benefits	
  of	
  their	
  soy	
  protein	
  and	
  discuss	
  the	
  
sustainability	
  of	
  soy	
  and	
  the	
  limited	
  environmental	
  impact	
  of	
  growing	
  it.	
   While	
  it	
  may	
  well	
  be	
  
true	
  that	
  soy	
  production	
  uses	
  less	
  water	
  and	
  provides	
  more	
  usable	
  protein	
  per	
  acre	
  than	
  other	
  
crops	
  or	
  animals,	
  these	
  markers	
  of	
  sustainability	
  come	
  at	
  a	
  big	
  price.	
  Currently	
  93%	
  of	
  all	
  soy	
  
grown	
  in	
  the	
  U.S.	
  is	
  genetically	
  modified	
  (Fernandez-­‐Cornejo	
  07/5/2012)	
  ii
.	
  A	
  number	
  of	
  studies	
  
over	
  the	
  past	
  decade	
  have	
  revealed	
  that	
  genetically	
  engineered	
  foods	
  can	
  pose	
  serious	
  risks	
  to	
  
humans,	
  domesticated	
  animals,	
  wildlife	
  and	
  the	
  environment.	
  Human	
  health	
  effects	
  can	
  include	
  
higher	
  risks	
  of	
  toxicity,	
  allergenicity,	
  antibiotic	
  resistance,	
  immune-­‐suppression	
  and	
  cancer.	
  As	
  for	
  
the	
  environment,	
  genetic	
  modification	
  allows	
  these	
  plants	
  to	
  be	
  sprayed	
  more	
  heavily	
  with	
  
herbicides	
  and	
  pesticides,	
  further	
  polluting	
  our	
  air,	
  land,	
  and	
  water	
  supplies.	
  There	
  are	
  additional	
  
health	
  problems	
  associated	
  with	
  the	
  use	
  of	
  soy	
  protein.	
  	
  Soy	
  contains	
  goitrogens	
  that	
  block	
  
thyroid	
  hormones,	
  lowering	
  metabolism,	
  disrupting	
  endocrine	
  function	
  and	
  can	
  lead	
  to	
  
Hashimotos	
  or	
  Graves	
  autoimmune	
  disorders.	
  	
  There	
  are	
  a	
  number	
  of	
  compounds	
  in	
  the	
  soybean	
  
that	
  inhibit	
  digestion.	
  In	
  addition,	
  soy	
  contains	
  high	
  amounts	
  of	
  phyto	
  (plant)	
  estrogens	
  which	
  
promote	
  high	
  estrogen	
  levels	
  (and	
  hormonal	
  imbalance)	
  in	
  both	
  men	
  and	
  women	
  (Daniel,	
  PhD,	
  
CCN	
  2005)	
  iii
.	
  
	
  
There	
  are	
  two	
  soy	
  protein	
  products	
  included:	
  	
  NutriBio	
  and	
  Bulkfoods.	
  	
  Both	
  are	
  pure	
  protein	
  
products	
  with	
  no	
  flavoring	
  or	
  additives.	
  	
  
	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   4	
  of	
  15	
  
Nutritional	
  Advantages	
  of	
  Advance	
  Protein	
  Powder	
  
	
  
Standardized	
  to	
  25	
  grams	
  of	
  protein	
  per	
  serving	
  
	
  	
  
Advance	
  
Protein	
  
Powder	
  
Blue	
  
Wave	
  
Source	
  
Organic	
  
Whey	
  
American	
  
Whey	
  
BulkFood	
  
Whey	
  
Isolate	
  
NutriBio	
  
Whey	
  
Isolate	
  
NutraBio	
  
Soy	
  
Protein	
  
Isolate	
  
BulkFood	
  
Soy	
  
Protein	
  
Isolate	
  
Serving	
  Size	
   29.2	
   	
  	
   29.8	
   28.5	
   27.5	
   28.3	
   28.7	
   27.5	
  
Calories	
   100.0	
   135.0	
   119.0	
   104.0	
   128.8	
   107.0	
   110.0	
   128.8	
  
Protein	
   25.0	
   25.0	
   25.0	
   25.0	
   25.0	
   25.0	
   25.0	
   25.0	
  
Carbohydrates	
   0.3	
   3.0	
   2.4	
   1.4	
   1.3	
   1.0	
   0.0	
   0.0	
  
Fat	
  in	
  gm	
   0.0	
   2.1	
   1.8	
   0.0	
   0.6	
   1.0	
   1.0	
   1.3	
  
Saturated	
  Fats	
   0.0	
   2.1	
   0.6	
   0.0	
   NA	
   1.0	
   NA	
   NA	
  
Cholesterol	
   0.0	
   31.3	
   47.6	
   4.5	
   NA	
   2.0	
   NA	
   NA	
  
*	
  All	
  Advance	
  International,	
  Inc	
  products	
  are	
  third-­‐party	
  tested	
  by	
  Eurofins	
  Scientific	
  S.E.	
  
	
  
	
  
	
  
	
  
	
  
	
  
Additional	
  information	
  about	
  the	
  various	
  products	
  
	
  	
   APP	
  
Blue	
  
Wave	
  
Source	
  
Organic	
  
Whey	
  
American	
  
Whey	
  
Whey-­‐
Isolate	
  
NutriBio	
  
Whey	
  
NutriBio	
  
Soy	
  
Bulk	
  Soy	
  
Isolate	
  
Digestibility	
  
98.1%	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
within	
  1	
  
hour	
  *	
  
NA	
   NA	
   NA	
   NA	
   NA	
   NA	
   NA	
  
Shelf	
  Life	
  
5	
  years	
  
*	
  
2	
  years	
   2	
  years	
   2	
  years	
   2	
  years	
   2	
  years	
   2	
  years	
   2	
  years	
  
Taste	
   NONE	
  
strong	
  
fish	
  
mild	
  
milk	
  
mild	
  milk	
   mild	
  
mild	
  
milk	
  
mild	
  soy	
   mild	
  soy	
  
Odor	
   NONE	
  
strong	
  
fish	
  
mild	
  
milk	
  
mild	
  milk	
   mild	
  
mild	
  
milk	
  
mild	
   mild	
  
GMO	
   NO	
   no	
   no	
  
yes	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
(feed)	
  
yes	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
(feed)	
  
yes	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
(feed)	
  
yes	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
(seed)	
  
yes	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  
(seed)	
  
	
   	
   	
   	
   	
   	
   	
   	
   	
  
*	
  All	
  Advance	
  International,	
  Inc	
  products	
  are	
  third-­‐party	
  tested	
  by	
  Eurofins	
  Scientific	
  S.E.	
  
	
  
	
  
	
  
	
  
	
  
	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   5	
  of	
  15	
  
APP	
  has	
  a	
  high	
  composition	
  of	
  naturally	
  occurring	
  organic	
  minerals	
  
	
  
	
  
The	
  chart	
  below	
  compares	
  the	
  mineral	
  content	
  of	
  the	
  eight	
  protein	
  products.	
  
	
  
Comparing	
  mineral	
  content	
  per	
  25gm	
  of	
  protein	
  as	
  a	
  percentage	
  of	
  the	
  RDA	
  
	
  	
   APP	
  
Blue	
  
Wave	
  
Source	
  
Organic	
  
Whey	
  
American	
  
Whey	
  
Whey-­‐
Isolate	
  
NutriBio	
  
Whey	
  
NutriBio	
  
Soy	
  
Bulk	
  
Soy	
  
Isolate	
  
Calcium	
   64.3%	
   12.5%	
   11.9%	
   12.0%	
   12.5%	
   14.0%	
   5.7%	
   4.7%	
  
Iron	
   21.3%	
   0%	
   0%	
   0%	
   0%	
   0%	
   22.2%	
   18.2%	
  
Magnesium	
   11.7%	
   0%	
   9.5%	
   0%	
   0%	
   5.0%	
   0%	
   4.9%	
  
Zinc	
   11.7%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
  
Selenium	
   0.1%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
  
Copper	
   6.7%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
  
Chromium	
   0.1%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
  
Sodium	
   2.4%	
   0%	
   0%	
   1.8%	
   0%	
   0%	
   16.8%	
   10.4%	
  
Potassium	
   4.5%	
   0%	
   0%	
   2.4%	
   0%	
   0%	
   0%	
   7.1%	
  
Phosphorus	
   18.4%	
   0%	
   9.5%	
   5.9%	
   0%	
   6.0%	
   0%	
   26.6%	
  
*	
  All	
  Advance	
  International,	
  Inc	
  products	
  are	
  third-­‐party	
  tested	
  by	
  Eurofins	
  Scientific	
  S.E.	
  
	
  
	
  
Because	
  APP	
  uses	
  all	
  parts	
  of	
  the	
  fish	
  including	
  bones	
  and	
  skin,	
  it	
  has	
  a	
  naturally	
  
occurring,	
  balanced	
  organic	
  mineral	
  profile,	
  something	
  not	
  possible	
  in	
  other	
  
protein	
  powders.	
  	
  Note	
  the	
  especially	
  good	
  levels	
  of	
  calcium	
  with	
  a	
  detail	
  of	
  the	
  
benefits	
  below:	
  
	
  
• The	
  CDCP	
  (Center	
  for	
  Disease	
  Control	
  &	
  Prevention)	
  estimates	
  most	
  Americans	
  
consume	
  only	
  40-­‐50%	
  of	
  the	
  RDA	
  of	
  calcium.	
  
• Most	
  supplements	
  and	
  foods	
  are	
  fortified	
  with	
  inferior	
  forms	
  of	
  calcium	
  that	
  
are	
  poorly	
  utilized	
  within	
  the	
  body.	
  
• The	
  calcium	
  in	
  APP	
  is	
  specific	
  to	
  the	
  fish	
  it	
  is	
  produced	
  from	
  and	
  is	
  therefore	
  a	
  
synergistic	
  component	
  with	
  all	
  the	
  nutrients	
  available.	
  	
   And,	
  because	
  protein	
  
enhances	
  calcium	
  absorption	
  it	
  becomes	
  more	
  bio-­‐available	
  (Kerstetter	
  et	
  al.	
  
2003).iv
	
  
• Calcium	
  is	
  needed	
  for	
  blood	
  pressure,	
  heartbeat,	
  and	
  nerve	
  regulation	
  
(Beauchamp	
  2006).v
	
  
• It	
  is	
  vital	
  for	
  bones,	
  teeth,	
  and	
  epithelial	
   (skin,	
  lung,	
  gut)	
  tissue.	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   6	
  of	
  15	
  
	
  
• Calcium	
  is	
  an	
  important	
  component	
  of	
  immune	
  function	
  (Alastra	
  2011).vi
	
  
	
  
• It	
  strongly	
  correlates	
  to	
  weight	
  regulation	
  and	
  loss	
  (Université	
  Laval	
  2009).vii
	
  
	
  
	
  
	
  
APP	
  is	
  easily	
  digestible	
  with	
  a	
  high	
  Biological	
  Value	
  (BV)	
  
	
  
Digestion	
  is	
  vital	
  to	
  all	
  nutrient	
  absorption	
  and	
  assimilation.	
   Many	
  people	
  have	
  compromised	
  
digestive	
  ability	
  due	
  to	
  factors	
  such	
  as	
  pharmaceutical	
  drug	
  use	
  and	
  age-­‐related	
  reduction	
  in	
  
digestive	
  enzyme	
  production.	
   Fish	
  in	
  general	
  is	
  one	
  of	
  the	
  easiest	
  proteins	
  to	
  digest,	
  while	
  
many	
  people	
  have	
  problems	
  digesting	
  the	
  proteins	
  in	
  dairy	
  and	
  soy	
  products.	
  
	
  
The	
  BV	
  value	
  of	
  APP	
  is	
  similar	
  to	
  that	
  of	
  Whey	
  Protein	
  and	
  far	
  superior	
  to	
  that	
  of	
  Soy.	
  
	
  
	
  
APP	
  has	
  fewer	
  calories	
  per	
  25	
  grams	
  of	
  protein	
  due	
  to	
  the	
  absence	
  of	
  carbohydrates	
  and	
  fats	
  
in	
  the	
  finished	
  product.	
  
	
  
	
  
	
  
Fish	
  Protein	
  Research	
  
	
  
Research	
  on	
  fish	
  protein	
  (FP)	
  supports	
  the	
  following	
  health	
  benefits	
  over	
  other	
  forms	
  of	
  
protein.	
  	
  It	
  has	
  been	
  most	
  often	
  compared	
  with	
  casein,	
  the	
  protein	
  found	
  in	
  milk.	
  
	
  
The	
  following	
  qualities	
  have	
  been	
  reported	
  in	
  various	
  research	
  studies	
  involving	
  fish	
  protein:	
  
	
  
• FP	
  has	
  been	
  shown	
  to	
  lower	
  LDL	
  cholesterol	
  levels	
  as	
  well	
  as	
  increase	
  HDL,	
  
improving	
  the	
  ratios	
  while	
  lowering	
  total	
  cholesterol	
  (Bergeron	
  1989)viii
,	
  (Bergeron	
  
1992).ix
	
  
• One	
  study	
  showed	
  lower	
  triglyceride	
  levels,	
  reduced	
  weight	
  gain	
  and	
  lower	
  blood	
  
pressure	
  from	
  FP	
  use.	
   The	
  report	
  suggests	
  the	
  amino	
  acid	
  ratios	
  may	
  be	
  a	
  
significant	
  contributor	
  to	
  these	
  findings	
  (Ait-­‐Yahia	
  2003)x
	
  (Ait	
  Yahia	
  2005).xi
	
  
• FP	
  can	
  lower	
  C-­‐Reactive	
  Protein	
  (a	
  blood	
  marker	
  for	
  inflammation)	
  which	
  has	
  a	
  
strong	
  correlation	
  with	
  CVD,	
  and	
  improve	
  insulin	
  sensitivity	
  in	
  people	
  with	
  a	
  BMI	
  >25	
  
(Ouellet	
  2008).xii
	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   7	
  of	
  15	
  
• Fish	
  protein	
  peptides	
  can	
  decrease	
  hypertensive	
  symptoms	
  (Kawasaki	
  2002).xiii
	
  
	
  
• Studies	
  show	
  FP	
  increases	
  immune	
  response	
  (Tang	
  2008).xiv
	
  
	
  
• FP	
  has	
  demonstrated	
  the	
  ability	
  to	
  restore	
  intestinal	
  integrity	
  (Cinq-­‐Mars	
  2008).xv
	
  
• Fish	
  protein	
  improves	
  insulin	
  sensitivity	
  in	
  insulin-­‐resistant	
  men	
  and	
  women	
  
(Ouellet	
  et	
  al.	
  2007).xvi
	
  
	
  
All	
  Natural,	
  Environmentally	
  Friendly,	
  Green	
  Manufacturing	
  Process	
  and	
  Sustainable	
  
Abundant	
  Sourcing	
  
	
  
Advance	
  Protein	
  Powder	
  is	
  naturally	
  sourced	
  from	
  multiple,	
  abundant,	
  and	
  sustainable	
  wild	
  
marine-­‐based	
  sources	
  worldwide.	
  	
  These	
  include	
  a	
  wide	
  variety	
  of	
  green-­‐list	
  fish	
  such	
  as	
  
sardines,	
  macros	
  and	
  other	
  similar	
  species	
  in	
  addition	
  to	
  having	
  the	
  widely	
  available	
  option	
  of	
  
utilizing	
  what	
  is	
  known	
  as	
  "bycatch".	
   Bycatch	
  are	
  very	
  small	
  fish	
  either	
  caught	
  unintentionally	
  
or	
  purchased	
  as	
  imperfect	
  discards	
  from	
  processing	
  facilities;	
  such	
  as	
  in	
  sardine	
  canning.	
  	
  APP	
  
can	
  also	
  be	
  produced	
  from	
  what	
  some	
  consider	
  a	
  waste	
  product	
  of	
  the	
  fishing	
  industry.	
  	
  In	
  
contrast	
  to	
  whey	
  though,	
  the	
  bycatch	
  used	
  here	
  are	
  not	
  exposed	
  to	
  toxic	
  feeds,	
  as	
  are	
  
commercial	
  dairy	
  cows.	
  	
  APP	
  is	
  completely	
  wild	
  and	
  not	
  sourced	
  from	
  any	
  farmed	
  fish	
  or	
  
farmed	
  fish	
  byproducts	
  and	
  contains	
  no	
  GMO.	
  	
  The	
  small	
  and	
  abundant	
  species	
  of	
  fish	
  used	
  as	
  
the	
  raw	
  material	
  make	
  APP	
  an	
  earth	
  and	
  ocean	
  friendly	
  product	
  with	
  a	
  low	
  carbon	
  footprint.	
  
	
  
Eurofins	
  Testing	
  
Samples	
  of	
  APP	
  have	
  undergone	
  multiple	
  rounds	
  of	
  analysis	
  by	
  Eurofins	
  Scientific,	
  Inc.,	
  a	
  
leader	
  in	
  food,	
  pharma,	
  and	
  environmental	
  laboratory	
  testing.	
  	
  Because	
  of	
  the	
  small	
  size	
  of	
  
the	
  fish,	
  the	
  heavy	
  metal/toxin	
  exposure	
  is	
  negligible.	
  	
  All	
  tests	
  have	
  confirmed	
  mercury,	
  lead,	
  
and	
  other	
  metals	
  at	
  <0.05	
  ppm.	
  	
  This	
  is	
  well	
  below	
  International	
  Pharmaceutical	
  Standard	
  of	
  
0.1	
  ppm.	
  	
  Further	
  analysis	
  by	
  Eurofins	
  showed	
  a	
  very	
  high	
  rate	
  -­‐	
  or	
  ease	
  -­‐	
  of	
  digestibility	
  
(using	
  a	
  Pepsin	
  Test)	
  making	
  the	
  amino	
  acids	
  and	
  minerals	
  very	
  bio-­‐available.	
  	
   Advance	
  
Protein	
  Powder	
  has	
  a	
  long,	
  stable	
  shelf	
  life;	
  a	
  sample	
  produced	
  in	
  2005	
  and	
  tested	
  in	
  2012	
  
showed	
  a	
  profile	
  consistent	
  with	
  a	
  current	
  batch	
  analysis.	
   	
  
	
  
	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   8	
  of	
  15	
  
Potential	
  for	
  Allergic	
  Response	
  
	
  
All	
  three	
  protein	
  sources	
  discussed	
  here	
  are	
  among	
  the	
  top	
  eight	
  most	
  allergenic	
  foods	
  
known.	
  These	
  eight	
  foods	
  include:	
   milk/dairy,	
  eggs,	
  soy,	
  peanuts,	
  tree	
  nuts,	
  shellfish,	
  finfish,	
  
and	
  wheat	
  (in	
  no	
  particular	
  order).	
   	
  Food	
  allergies	
  can	
  be	
  a	
  problem	
  for	
  people	
  and	
  in	
  some	
  
cases	
  a	
  very	
  serious	
  one.	
  	
  The	
  CDC's	
  (Centers	
  for	
  Disease	
  Control	
  and	
  Prevention)	
  National	
  
Center	
  for	
  Health	
  Statistics	
  reports	
  that	
  these	
  foods	
  account	
  for	
  90	
  percent	
  of	
  all	
  food	
  
allergies.	
  	
  According	
  to	
  the	
  National	
  Institute	
  of	
  Health	
  (NIH),	
  allergy	
  to	
  eggs,	
  milk,	
  peanuts,	
  
tree	
  nuts,	
  soy,	
  and	
  wheat	
  are	
  most	
  likely	
  to	
  occur	
  in	
  children.	
  	
  In	
  Adults,	
  the	
  most	
  common	
  
foods	
  that	
  cause	
  allergic	
  (anaphylaxis)	
  reactions	
  are	
  shellfish,	
  peanut	
  and	
  tree	
  nuts,	
  and	
  then	
  
fish.	
  
	
  
The	
  following	
  data	
  is	
  taken	
  in	
  part	
  from	
  a	
  report	
  from	
  FARE,	
  a	
  nonprofit	
  organization	
  for	
  
Food	
  Allergy	
  Research	
  &	
  Education)	
  xvii
	
  
Peanuts:	
   0.6	
  -­‐	
  1.3%	
  
Tree	
  nuts:	
   0.4	
  -­‐	
  0.6%	
  
Fish:	
   0.4%	
  
Crustacean	
  shellfish	
  (crab,	
  shrimp,	
  lobster...):	
   1.2%	
  
All	
  seafood:	
   0.6%	
  in	
  children	
  and	
  2.8%	
  in	
  adults	
  
Milk:	
   2.5%	
  in	
  young	
  children	
  and	
  0.2	
  -­‐	
  0.4%	
  in	
  general	
  
population	
  
Soy:	
   0.4%	
  in	
  children	
  and	
  0.1%	
  in	
  adults	
  xviii
	
  
	
  
	
   	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   9	
  of	
  15	
  
	
  
Potential	
  retail	
  food	
  uses	
  for	
  APP	
  include:	
  
	
  
• Food	
  bars	
  with	
  a	
  varied	
  protein,	
  fat,	
  &	
  carbohydrate	
  ratios	
  and	
  ingredients	
  
o Sports	
  nutrition:	
  	
  bodybuilders,	
  climbers,	
  runners,	
  etc.	
  for	
  both	
  pre	
  and	
  post	
  
workout.	
  	
  Private	
  label	
  options	
  for	
  gyms	
  and	
  athletic	
  clubs	
  
o Snacks:	
  	
  healthy	
  alternatives	
  for	
  kids	
  and	
  adults	
  
o Specialty:	
  	
  blood	
  sugar	
  regulation	
  and	
  weight	
  loss	
  
• Drink	
  powder	
  blends	
  and	
  pre-­‐blended	
  drinks	
  
o Formulation	
  options	
  for	
  the	
  categories	
  listed	
  above	
  with	
  higher	
  protein	
  and	
  
additional	
  nutrition	
  potential	
  than	
  possible	
  in	
  bars	
  
o Meal	
  replacement	
  "on	
  the	
  go"	
  drinks	
  for	
  regular	
  use	
  
o Meal	
  replacement	
  drinks	
  or	
  blends	
  for	
  weight	
  loss	
  and	
  detoxification	
  
o Geriatric	
  nutrition	
  drinks	
  
o Balanced	
  nutrition	
  during	
  pregnancy	
  
	
  
Potential	
  therapeutic	
  uses	
  for	
  APP	
  include:	
  
	
  
• Rapidly	
  reversing	
  the	
  effects	
  of	
  severe	
  malnutrition	
  in	
  children	
  and	
  adults	
  in	
  
global	
  hotspots	
  
• Clinical	
  use	
  in	
  a	
  physical	
  therapy	
  setting	
  to	
  assist	
  in	
  bone	
  and	
  tissue	
  growth	
  
after	
  injury	
  and	
  surgery	
  
• As	
  a	
  nutritional	
  supplement	
  and	
  calcium	
  source	
  for	
  people	
  with	
  osteopenia	
  
and	
  osteoporosis	
  
• To	
  reduce	
  incidence	
  of	
  sarcopenia	
  in	
  the	
  aged	
  and	
  infirm	
  
• As	
  a	
  superior	
  protein	
  source	
  in	
  a	
  hospital	
  or	
  rehabilitation	
  setting	
  to	
  replace	
  
the	
  soy	
  protein	
  in	
  widely	
  available	
  pre-­‐made	
  "nutrition"	
  drinks	
  
	
  
	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   10	
  of	
  15	
  
In	
  Summary	
  
	
  
Advance	
  Protein	
  Powder	
  is	
  an	
  exciting	
  new	
  product	
  and	
  proprietary	
  process	
  technology	
  with	
  
high	
  potential	
  as	
  an	
  all-­‐natural	
  protein/mineral	
  supplement,	
  in	
  multiple	
  retail	
  food	
  products,	
  
and	
  for	
  use	
  in	
  therapeutic	
  nutritional	
  therapies.	
  	
  APP	
  is	
  comparable	
  in	
  BV	
  value	
  to	
  the	
  best	
  
quality	
  whey	
  protein	
  products	
  on	
  the	
  market	
  and	
  superior	
  in	
  balanced	
  nutrition	
  due	
  to	
  the	
  
unique	
  amino	
  acid	
  profile	
  and	
  abundance	
  of	
  naturally	
  occurring	
  organically	
  bound	
  minerals	
  
found	
  in	
  fish.	
  
	
  
	
  
	
  Julie	
  Spero,	
  MBA,	
  NC	
  	
  
	
  President	
  
i
	
  “Nutrition	
  and	
  Energy	
  Bars	
  “Wise	
  Traditions	
  in	
  Food,	
  Farming	
  and	
  the	
  Healing	
  Arts”.	
  Weston	
  
A.	
  Price	
  Foundation,	
  Winter	
  2002.	
  http://www.westonaprice.org/index.html	
  	
  
	
  
ii
Fernandez-­‐Corenego,	
  Jorge.	
  USDA,	
  National	
  Agricultural	
  Statistics	
  Servce,	
  “Recent	
  Trends	
  in	
  
GE	
  Adoption.”	
  Last	
  modified	
  07/05/2012.	
  http://www.ers.usda.gov/data-­‐products/adoption-­‐
of-­‐genetically-­‐engineered-­‐crops-­‐in-­‐the-­‐us/recent-­‐trends-­‐in-­‐ge-­‐adoption.aspx.	
  	
  
	
  
iii
Daniel,	
  PhD,	
  CCN,	
  Kaayla	
  T.	
  The	
  Whole	
  Soy	
  Story.	
  Washington,	
  DC:	
  New	
  Trends	
  Publishing,	
  
Inc.,	
  2005.	
  
iv
Jane	
  E.	
  Kerstetter,	
  Kimberly	
  O.	
  O'Brien,	
  and	
  Karl	
  L.	
  Insogna,	
  "Low	
  Protein	
  Intake:	
  The	
  impact	
  
of	
  Calcium	
  and	
  Bone	
  Homeostasis	
  in	
  Humans,"	
  The	
  Journal	
  of	
  Nutrition,	
  133,	
  no.	
  3	
  (2003):	
  
8555-­‐8615.	
  
	
  
v
Beauchamp,	
  Kimberley,	
  ND.	
  Bastyr	
  Center	
  for	
  Natural	
  Health,	
  “Calcium	
  Reduces	
  High	
  Blood	
  
Pressure.”	
  Last	
  modified	
  2006.	
  http://www.bastyrcenter.org/content/view/1029.	
  	
  
	
  
vi
Alastra,	
  Holly.	
  “The	
  Role	
  of	
  Calcium	
  in	
  the	
  Bones	
  and	
  Immune	
  System.”	
  Last	
  modified	
  2011.	
  
http://www.livestrong.com/article/526824-­‐the-­‐role-­‐of-­‐calcium-­‐in-­‐the-­‐bones-­‐and-­‐immune-­‐
system/.	
  	
  
	
  
vii
Université	
  Laval	
  (2009,	
  March	
  19).	
  “Diet	
  Rich	
  in	
  Calcium	
  Aids	
  Weight	
  Loss	
  in	
  People	
  with	
  
Calcium	
  Deficient	
  Diets”.	
  Science	
  Daily.	
  	
  
	
  
viii
N.	
  Bergeron,	
  H.	
  Jacques,	
  “Influence	
  of	
  fish	
  protein	
  as	
  compared	
  to	
  casein	
  and	
  soy	
  protein	
  on	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   11	
  of	
  15	
  
serum	
  and	
  liver	
  lipids,	
  and	
  serum	
  lipoprotein	
  cholesterol	
  levels	
  in	
  the	
  rabbits”.	
  
Atherosclerosis,	
  August,	
  no.	
  78	
  (1989):	
  113-­‐21.	
  	
  
	
  
ix
N.	
  Bergeron,	
  Y.	
  Deshailes,	
  H.	
  Jacques,	
  “Factorial	
  experiment	
  to	
  determine	
  influence	
  of	
  fish	
  
protein	
  and	
  fish	
  oil	
  on	
  serum	
  and	
  liver	
  lipids	
  in	
  rabbits”.	
  Nutrition,	
  Sept-­‐Oct,	
  no.	
  8	
  (1992):	
  
354-­‐8	
  
	
  
x
D.	
  Ait-­‐Yahia,	
  et	
  al,	
  “Dietary	
  fish	
  protein	
  lowers	
  blood	
  pressure	
  and	
  alters	
  tissue	
  
polyunsaturated	
  fatty	
  acid	
  composition	
  in	
  spontaneously	
  hypertensive	
  rats.,”	
  Nutrition,	
  
April,	
  no.	
  19	
  (2003):	
  342-­‐6	
  
	
  
xi
D.	
  Ait-­‐Yahia,	
  et	
  al,	
  “Fish	
  protein	
  improves	
  blood	
  pressure	
  but	
  alters	
  HDL2	
  and	
  HDL3	
  
composition	
  and	
  tissue	
  lipoprotein	
  lipase	
  activities	
  in	
  spontaneously	
  hypertensive	
  rats.,”	
  
European	
  Journal	
  of	
  Nutrition,	
  44,	
  no.	
  (2005):	
  10-­‐15	
  
xii
Veronique	
  Oullet,	
  et	
  al,	
  “Dietary	
  Cod	
  Protein	
  Reduces	
  Plasma	
  C-­‐Reactive	
  Protein	
  in	
  Insulin-­‐
Resistant	
  Men	
  and	
  Women,”	
  The	
  Journal	
  of	
  Nutrition,	
  138,	
  no.	
  December	
  (2008):	
  2386-­‐2391.	
  
	
  
xiii
T	
  Kawasaki,	
  “Antihypertensive	
  effect	
  and	
  safety	
  evaluation	
  of	
  vegetable	
  drink	
  with	
  peptides	
  
derived	
  from	
  sardine	
  protein	
  hydrolysates	
  on	
  mild	
  hypertensive,	
  high-­‐normal	
  and	
  normal	
  
blood	
  pressure	
  subjects,”	
  Center	
  for	
  Health	
  and	
  Sports	
  Science,	
  93,	
  no.	
  Oct	
  (2002):	
  208-­‐18	
  
	
  
xiv
Hong-­‐gang	
  Tang,	
  et	
  al,	
  “Effects	
  of	
  fish	
  protein	
  hydrolysate	
  on	
  growth	
  performance	
  and	
  
humoral	
  immune	
  response	
  in	
  large	
  yellow	
  croaker	
  (Pseudosciaena	
  crocea	
  R.),”	
  Journal	
  of	
  
Zhejiang	
  University	
  SCIENCE	
  B,	
  9,	
  no.9	
  (2008):	
  684-­‐690.	
  
xv
Crystal	
  D.	
  Cinq-­‐Mars,	
  “Investigations	
  into	
  inhibitor	
  Type	
  and	
  Mode,	
  Simulated	
  
Gastrointestinal	
  Digestion	
  and	
  Cell	
  Transport	
  of	
  the	
  Angiotensin	
  I-­‐Converting	
  Enzyme-­‐
Inhibitory	
  Peptides	
  in	
  Pacific	
  Hake	
  (Merluccius	
  productus)	
  Fillet	
  Hydrolysate,”	
  Journal	
  of	
  
Agricultural	
  and	
  Food	
  Chemistry,	
  52,	
  no.	
  2	
  (2008):	
  410-­‐410	
  
xvi
Ouellet,	
  Veronique,	
  Julie	
  Marois,	
  and	
  S.	
  John	
  Weisnagel.	
  "Dietary	
  Cod	
  Protein	
  Improves	
  
Insulin	
  Sensitivity	
  in	
  Insulin-­‐Resistant	
  Men	
  and	
  Women."	
  Diabetes	
  Care.	
  no.	
  11	
  (2007):	
  2816-­‐
2821.	
  
	
  
xvii
FARE:	
  Food	
  Allergy	
  Research	
  &	
  Education,	
  “Food	
  Allergy	
  Facts	
  and	
  Statistics	
  for	
  the	
  U.S.”	
  Last	
  
modified	
  10/3/2011.	
  http://www.foodallergy.org/document.doc?id=194.	
  	
  
	
  
xviii
Savage	
  JH,	
  Kaeding	
  AJ,	
  Matsui	
  EC,	
  Wood	
  RA.	
  The	
  natural	
  history	
  of	
  soy	
  allergy.	
  J	
  Allergy	
  Clin	
  
Immunol,	
  2010;125:683-­‐86	
   	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   12	
  of	
  15	
  
	
  
AMINO	
  ACID	
  COMPOSITION	
  WITH	
  COMPARISON	
  GRAPHS	
  
	
  	
   	
  	
  
Advance	
  
Protein	
  
Powder	
  
*	
  
Blue	
  
Wave	
  
Source	
  
Organic	
  
Whey	
  
American	
  
Whey	
  
Whey-­‐
Isolate	
  
NutriBio	
  
Whey	
  
NutriBio	
  
Soy	
  
Bulk	
  
Soy	
  
Isolate	
  
Essential	
  
Histidine	
   0.36	
   0.21	
   0.23	
   0.48	
   0.47	
   0.42	
   0.66	
   NA	
  
Isoleucine*	
   0.59	
   0.54	
   1.17	
   1.87	
   1.75	
   1.58	
   1.24	
   1.50	
  
Leucine*	
   1.02	
   1.01	
   2.42	
   2.63	
   3.03	
   2.74	
   2.07	
   2.50	
  
Lysine*	
   1.14	
   0.93	
   1.95	
   2.20	
   3.03	
   2.74	
   1.58	
   NA	
  
Methionine	
   0.73	
   0.45	
   0.50	
   0.65	
   0.63	
   0.57	
   0.35	
   0.41	
  
Phenylalanine	
   0.54	
   0.57	
   0.47	
   0.88	
   0.91	
   0.82	
   1.32	
   NA	
  
Threonine	
   0.63	
   0.72	
   1.71	
   1.80	
   1.91	
   1.72	
   0.95	
   1.16	
  
Tryptophan	
   0.31	
   0.60	
   0.23	
   0.51	
   0.50	
   0.45	
   0.35	
   0.38	
  
Valine	
   0.67	
   0.70	
   1.03	
   1.48	
   1.44	
   1.30	
   1.26	
   1.50	
  
NonEssential	
  
Alanine	
   0.85	
   1.12	
   0.94	
   1.27	
   1.44	
   1.30	
   1.09	
   1.34	
  
Arginine	
   0.87	
   1.15	
   0.31	
   0.08	
   0.66	
   0.59	
   1.93	
   2.34	
  
Aspartic	
  Acid	
   1.33	
   1.43	
   2.50	
   3.45	
   3.03	
   2.74	
   2.93	
   3.59	
  
Cysteine	
   0.24	
   0.70	
   0.08	
   0.75	
   0.81	
   0.73	
   0.32	
   0.38	
  
Glutamic	
  Acid	
   1.93	
   2.11	
   5.32	
   4.70	
   NA	
   4.83	
   4.86	
   NA	
  
Glycine	
   0.74	
   2.03	
   0.39	
   0.48	
   NA	
   0.45	
   1.06	
   NA	
  
Proline	
   0.55	
   1.02	
   1.48	
   1.54	
   1.72	
   1.55	
   1.29	
   1.63	
  
Serine	
   0.48	
   0.98	
   1.09	
   1.28	
   1.16	
   1.05	
   1.32	
   1.69	
  
Tyrosine	
   0.45	
   0.46	
   0.47	
   0.69	
   0.84	
   0.76	
   0.98	
   NA	
  
*	
  All	
  Advance	
  International,	
  Inc	
  products	
  are	
  third-­‐party	
  tested	
  for	
  quality	
  by	
  Eurofins	
  Scientific	
  
S.E.	
  
	
  
	
  
	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   13	
  of	
  15	
  
	
  
	
  
0.00	
  
1.00	
  
2.00	
  
3.00	
  
4.00	
  
5.00	
  
6.00	
  
Advance	
  Protein	
  Powder	
  *	
  
BlueWave	
  
Source	
  Organic	
  Whey	
  
American	
  Whey	
  
Whey-­‐Isolate	
  
NutriBio	
  Whey	
  
NutriBio	
  Soy	
  
Bulk	
  Soy	
  Isolate	
  
AMINO	
  ACID	
  COMPARISON	
  PER	
  25	
  GRAMS	
  
OF	
  PROTEIN	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   14	
  of	
  15	
  
	
  
	
  
	
  
MINERAL	
  COMPOSITION	
  	
  
RDA	
   	
  	
   MINERALS	
   APP	
  *	
  
BlueWav
e	
  
Source	
  
Organic	
  
Whey	
  
America
n	
  Whey	
  
Whey-­‐
Isolate	
  
NutriBi
o	
  Whey	
  
NutriBi
o	
  Soy	
  
Bulk	
  
Soy	
  
Isolat
e	
  
100
0	
   mg	
   Calcium	
  
64.3%	
   12.5%	
   11.9%	
   12.0%	
   12.5%	
   14.0%	
   5.7%	
   4.7%	
  
18	
   mg	
   Iron	
  
21.3%	
   0%	
   0%	
   0%	
   0%	
   0%	
   22.2%	
  
18.2
%	
  
400	
   mg	
  
Magnesiu
m	
  
11.7%	
   0%	
   9.5%	
   0%	
   0%	
   5.0%	
   0%	
   4.9%	
  
15	
   mg	
   Zinc	
   11.7%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
  
70	
  
mc
g	
   Selenium	
  
0.1%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
  
2	
   mg	
   Copper	
   6.7%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
  
120	
  
mc
g	
   Chromium	
  
0.1%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
   0%	
  
240
0	
   mg	
   Sodium	
  
2.4%	
   0%	
   0%	
   1.8%	
   0%	
   0%	
   16.8%	
  
10.4
%	
  
350
0	
   mg	
   Potassium	
  
4.5%	
   0%	
   0%	
   2.4%	
   0%	
   0%	
   0%	
   7.1%	
  
100
0	
   mg	
  
Phosphoru
s	
  
18.4%	
   0%	
   9.5%	
   5.9%	
   0%	
   6.0%	
   0%	
  
26.6
%	
  
*	
  All	
  Advance	
  International,	
  Inc	
  products	
  are	
  third-­‐party	
  tested	
  for	
  quality	
  by	
  Eurofins	
  Scientific	
  S.E.	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   15	
  of	
  15	
  
0.0%	
  
10.0%	
  
20.0%	
  
30.0%	
  
40.0%	
  
50.0%	
  
60.0%	
  
70.0%	
  
APP	
  *	
  
BlueWave	
  
Source	
  Organic	
  Whey	
  
American	
  Whey	
  
Whey-­‐Isolate	
  
NutriBio	
  Whey	
  
NutriBio	
  Soy	
  
Bulk	
  Soy	
  Isolate	
  
Mineral	
  Content	
  as	
  a	
  percentage	
  of	
  RDA	
  in	
  25grams	
  of	
  protein	
  
 	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
  	
   	
  
Julie	
  Spero,	
  MBA,	
  NC	
   	
   16	
  of	
  15	
  
	
  

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Advance Protein Powder Nutritional Report

  • 1.                                   Julie  Spero,  MBA,  NC     1  of  15         Advance  Protein  Powder  Nutritional  Report          Julie  Spero,  MBA,  NC    President,  National  Association  of  Nutrition  Professionals     18  May  2014     Overview:     Advance  Protein  Powder  (APP)  is  a  high  quality,  organically  derived,  wild  marine-­‐based   protein  powder,  which  is  highly  stable  with  a  shelf  life  of  over  5  years.    It  is  virtually  odorless   and  tasteless  with  high  levels  of  naturally  occurring  organic  minerals  giving  it  a  nutritional   profile  superior  to  other  protein  powders  on  the  market.    APP  is  made  using  a  patent-­‐ pending  manufacturing  process  that  is  both  green  and  sustainable.    It  is  non-­‐hygroscopic  and   very  moisture  resistant,  contributing  to  its  long  shelf  life.    This  report  presents  an  overview  of   the  health  benefits  of  the  all  natural  Advance  Protein  Powder  comparing  it  with  BlueWave,   another  fish  protein  product  on  the  market  and  also  with  several  examples  from  the  two   most  common  protein  supplement  categories  available:  whey  and  soy.        
  • 2.                                   Julie  Spero,  MBA,  NC     2  of  15   About  Whey  protein  powder     Whey  used  to  be  considered  a  dairy  industry  waste  product.  Whey  is  what  remains  after  the   butter,  cream,  milk  is  drawn  off  and  the  cheese  has  been  made.  The  dairy  industry  long   considered  whey  a  problem  because  dumping  it  into  sewer  systems  or  feeding  it  to  pigs  cost   as  much  or  slightly  more  than  the  value  of  the  whey  as  a  commodity.  This  problem  was   solved  when  manufacturers  developed  techniques  for  drying  the  whey  at  high  temperatures   and  putting  the  powders  into  body  building  powders,  high  protein  bars  and  other  food   products.i     While  there  are  some  high  quality  whey  protein  powders  available,  many  more  are  of   marginal  or  poor  quality.   The  most  expensive  and  better  quality  products  are  made  from   organic  milk  and  processed  at  low  temperatures  to  preserve  the  maximum  amino  acid   content  potential  and  maintain  a  full  range  of  important  protein  components  such  as   immunoglobulins  and  serum  albumin  (which  are  also  present  in  APP  fish  protein).   The  quality   of  other  whey  protein  powders  can  vary  widely  depending  on  the  source  of  the  milk  used  as   well  as  the  various  steps  in  processing.     Commercial  milk  often  contains  growth  hormone   (rBGH)  and  a  number  of  antibiotics;  the  FDA  has  approved  thirty.   An  estimated  sixty  percent   of  herbicides  used  in  the  U.S.  as  well  as  pesticides  and  other  petrochemicals  are  applied  to   produce  higher  yields  of  feed  crops  that  are  eaten  by  commercial  dairy  cows  and  are  present   in  the  milk  they  produce.   As  you  can  see,  the  quality  of  the  whey  can  only  be  as  good  as  the   quality  of  the  food,  nutrition  and  care  given  to  the  cows.     The  Whey  protein  products  chosen  for  this  comparison  represent  products  that  are  available   for  purchase  in  bulk  or  commonly  used  in  protein  drinks  and  bars.    They  include  an  organic   whey  protein  product  from  Source  Organic  who  declare  their  cows  have  never  been  given   hormones,  antibiotics,  steroids,  or  genetically  modified  feed  (GMO).  The  others  are  plain   protein  products  with  no  flavoring  added.    Whey  protein  (of  good  quality)  is  one  of  the  most   bio-­‐available  sources  of  supplemental  protein  available  at  96-­‐98%.   As  mentioned,  the  quality   can  vary  considerably  depending  on  the  milk  source  and  the  methods  used  in  processing.  
  • 3.                                   Julie  Spero,  MBA,  NC     3  of  15     • Source  Organic  Whey  protein  is  processed  using  low  temperature  drying  and  filtration   and  therefore  retains  immune  components  as  well  as  glutathione.     • American  whey  protein  is  unflavored,  however  it  does  contains  xanthan  gum     • Both  American  Whey  and  NutriBio  are  whey  protein  isolates  with  protein  levels  at   around  90%.     About  Soy  protein  powder     The  Solae  Company,  owned  by  DuPont,  is  a  leader  in  developing  soy  products  and  ingredients   for  food.   On  their  website  they  tout  the  healthy  benefits  of  their  soy  protein  and  discuss  the   sustainability  of  soy  and  the  limited  environmental  impact  of  growing  it.   While  it  may  well  be   true  that  soy  production  uses  less  water  and  provides  more  usable  protein  per  acre  than  other   crops  or  animals,  these  markers  of  sustainability  come  at  a  big  price.  Currently  93%  of  all  soy   grown  in  the  U.S.  is  genetically  modified  (Fernandez-­‐Cornejo  07/5/2012)  ii .  A  number  of  studies   over  the  past  decade  have  revealed  that  genetically  engineered  foods  can  pose  serious  risks  to   humans,  domesticated  animals,  wildlife  and  the  environment.  Human  health  effects  can  include   higher  risks  of  toxicity,  allergenicity,  antibiotic  resistance,  immune-­‐suppression  and  cancer.  As  for   the  environment,  genetic  modification  allows  these  plants  to  be  sprayed  more  heavily  with   herbicides  and  pesticides,  further  polluting  our  air,  land,  and  water  supplies.  There  are  additional   health  problems  associated  with  the  use  of  soy  protein.    Soy  contains  goitrogens  that  block   thyroid  hormones,  lowering  metabolism,  disrupting  endocrine  function  and  can  lead  to   Hashimotos  or  Graves  autoimmune  disorders.    There  are  a  number  of  compounds  in  the  soybean   that  inhibit  digestion.  In  addition,  soy  contains  high  amounts  of  phyto  (plant)  estrogens  which   promote  high  estrogen  levels  (and  hormonal  imbalance)  in  both  men  and  women  (Daniel,  PhD,   CCN  2005)  iii .     There  are  two  soy  protein  products  included:    NutriBio  and  Bulkfoods.    Both  are  pure  protein   products  with  no  flavoring  or  additives.      
  • 4.                                   Julie  Spero,  MBA,  NC     4  of  15   Nutritional  Advantages  of  Advance  Protein  Powder     Standardized  to  25  grams  of  protein  per  serving       Advance   Protein   Powder   Blue   Wave   Source   Organic   Whey   American   Whey   BulkFood   Whey   Isolate   NutriBio   Whey   Isolate   NutraBio   Soy   Protein   Isolate   BulkFood   Soy   Protein   Isolate   Serving  Size   29.2       29.8   28.5   27.5   28.3   28.7   27.5   Calories   100.0   135.0   119.0   104.0   128.8   107.0   110.0   128.8   Protein   25.0   25.0   25.0   25.0   25.0   25.0   25.0   25.0   Carbohydrates   0.3   3.0   2.4   1.4   1.3   1.0   0.0   0.0   Fat  in  gm   0.0   2.1   1.8   0.0   0.6   1.0   1.0   1.3   Saturated  Fats   0.0   2.1   0.6   0.0   NA   1.0   NA   NA   Cholesterol   0.0   31.3   47.6   4.5   NA   2.0   NA   NA   *  All  Advance  International,  Inc  products  are  third-­‐party  tested  by  Eurofins  Scientific  S.E.               Additional  information  about  the  various  products       APP   Blue   Wave   Source   Organic   Whey   American   Whey   Whey-­‐ Isolate   NutriBio   Whey   NutriBio   Soy   Bulk  Soy   Isolate   Digestibility   98.1%                       within  1   hour  *   NA   NA   NA   NA   NA   NA   NA   Shelf  Life   5  years   *   2  years   2  years   2  years   2  years   2  years   2  years   2  years   Taste   NONE   strong   fish   mild   milk   mild  milk   mild   mild   milk   mild  soy   mild  soy   Odor   NONE   strong   fish   mild   milk   mild  milk   mild   mild   milk   mild   mild   GMO   NO   no   no   yes                       (feed)   yes                       (feed)   yes                       (feed)   yes                             (seed)   yes                             (seed)                     *  All  Advance  International,  Inc  products  are  third-­‐party  tested  by  Eurofins  Scientific  S.E.              
  • 5.                                   Julie  Spero,  MBA,  NC     5  of  15   APP  has  a  high  composition  of  naturally  occurring  organic  minerals       The  chart  below  compares  the  mineral  content  of  the  eight  protein  products.     Comparing  mineral  content  per  25gm  of  protein  as  a  percentage  of  the  RDA       APP   Blue   Wave   Source   Organic   Whey   American   Whey   Whey-­‐ Isolate   NutriBio   Whey   NutriBio   Soy   Bulk   Soy   Isolate   Calcium   64.3%   12.5%   11.9%   12.0%   12.5%   14.0%   5.7%   4.7%   Iron   21.3%   0%   0%   0%   0%   0%   22.2%   18.2%   Magnesium   11.7%   0%   9.5%   0%   0%   5.0%   0%   4.9%   Zinc   11.7%   0%   0%   0%   0%   0%   0%   0%   Selenium   0.1%   0%   0%   0%   0%   0%   0%   0%   Copper   6.7%   0%   0%   0%   0%   0%   0%   0%   Chromium   0.1%   0%   0%   0%   0%   0%   0%   0%   Sodium   2.4%   0%   0%   1.8%   0%   0%   16.8%   10.4%   Potassium   4.5%   0%   0%   2.4%   0%   0%   0%   7.1%   Phosphorus   18.4%   0%   9.5%   5.9%   0%   6.0%   0%   26.6%   *  All  Advance  International,  Inc  products  are  third-­‐party  tested  by  Eurofins  Scientific  S.E.       Because  APP  uses  all  parts  of  the  fish  including  bones  and  skin,  it  has  a  naturally   occurring,  balanced  organic  mineral  profile,  something  not  possible  in  other   protein  powders.    Note  the  especially  good  levels  of  calcium  with  a  detail  of  the   benefits  below:     • The  CDCP  (Center  for  Disease  Control  &  Prevention)  estimates  most  Americans   consume  only  40-­‐50%  of  the  RDA  of  calcium.   • Most  supplements  and  foods  are  fortified  with  inferior  forms  of  calcium  that   are  poorly  utilized  within  the  body.   • The  calcium  in  APP  is  specific  to  the  fish  it  is  produced  from  and  is  therefore  a   synergistic  component  with  all  the  nutrients  available.     And,  because  protein   enhances  calcium  absorption  it  becomes  more  bio-­‐available  (Kerstetter  et  al.   2003).iv   • Calcium  is  needed  for  blood  pressure,  heartbeat,  and  nerve  regulation   (Beauchamp  2006).v   • It  is  vital  for  bones,  teeth,  and  epithelial   (skin,  lung,  gut)  tissue.  
  • 6.                                   Julie  Spero,  MBA,  NC     6  of  15     • Calcium  is  an  important  component  of  immune  function  (Alastra  2011).vi     • It  strongly  correlates  to  weight  regulation  and  loss  (Université  Laval  2009).vii         APP  is  easily  digestible  with  a  high  Biological  Value  (BV)     Digestion  is  vital  to  all  nutrient  absorption  and  assimilation.   Many  people  have  compromised   digestive  ability  due  to  factors  such  as  pharmaceutical  drug  use  and  age-­‐related  reduction  in   digestive  enzyme  production.   Fish  in  general  is  one  of  the  easiest  proteins  to  digest,  while   many  people  have  problems  digesting  the  proteins  in  dairy  and  soy  products.     The  BV  value  of  APP  is  similar  to  that  of  Whey  Protein  and  far  superior  to  that  of  Soy.       APP  has  fewer  calories  per  25  grams  of  protein  due  to  the  absence  of  carbohydrates  and  fats   in  the  finished  product.         Fish  Protein  Research     Research  on  fish  protein  (FP)  supports  the  following  health  benefits  over  other  forms  of   protein.    It  has  been  most  often  compared  with  casein,  the  protein  found  in  milk.     The  following  qualities  have  been  reported  in  various  research  studies  involving  fish  protein:     • FP  has  been  shown  to  lower  LDL  cholesterol  levels  as  well  as  increase  HDL,   improving  the  ratios  while  lowering  total  cholesterol  (Bergeron  1989)viii ,  (Bergeron   1992).ix   • One  study  showed  lower  triglyceride  levels,  reduced  weight  gain  and  lower  blood   pressure  from  FP  use.   The  report  suggests  the  amino  acid  ratios  may  be  a   significant  contributor  to  these  findings  (Ait-­‐Yahia  2003)x  (Ait  Yahia  2005).xi   • FP  can  lower  C-­‐Reactive  Protein  (a  blood  marker  for  inflammation)  which  has  a   strong  correlation  with  CVD,  and  improve  insulin  sensitivity  in  people  with  a  BMI  >25   (Ouellet  2008).xii  
  • 7.                                   Julie  Spero,  MBA,  NC     7  of  15   • Fish  protein  peptides  can  decrease  hypertensive  symptoms  (Kawasaki  2002).xiii     • Studies  show  FP  increases  immune  response  (Tang  2008).xiv     • FP  has  demonstrated  the  ability  to  restore  intestinal  integrity  (Cinq-­‐Mars  2008).xv   • Fish  protein  improves  insulin  sensitivity  in  insulin-­‐resistant  men  and  women   (Ouellet  et  al.  2007).xvi     All  Natural,  Environmentally  Friendly,  Green  Manufacturing  Process  and  Sustainable   Abundant  Sourcing     Advance  Protein  Powder  is  naturally  sourced  from  multiple,  abundant,  and  sustainable  wild   marine-­‐based  sources  worldwide.    These  include  a  wide  variety  of  green-­‐list  fish  such  as   sardines,  macros  and  other  similar  species  in  addition  to  having  the  widely  available  option  of   utilizing  what  is  known  as  "bycatch".   Bycatch  are  very  small  fish  either  caught  unintentionally   or  purchased  as  imperfect  discards  from  processing  facilities;  such  as  in  sardine  canning.    APP   can  also  be  produced  from  what  some  consider  a  waste  product  of  the  fishing  industry.    In   contrast  to  whey  though,  the  bycatch  used  here  are  not  exposed  to  toxic  feeds,  as  are   commercial  dairy  cows.    APP  is  completely  wild  and  not  sourced  from  any  farmed  fish  or   farmed  fish  byproducts  and  contains  no  GMO.    The  small  and  abundant  species  of  fish  used  as   the  raw  material  make  APP  an  earth  and  ocean  friendly  product  with  a  low  carbon  footprint.     Eurofins  Testing   Samples  of  APP  have  undergone  multiple  rounds  of  analysis  by  Eurofins  Scientific,  Inc.,  a   leader  in  food,  pharma,  and  environmental  laboratory  testing.    Because  of  the  small  size  of   the  fish,  the  heavy  metal/toxin  exposure  is  negligible.    All  tests  have  confirmed  mercury,  lead,   and  other  metals  at  <0.05  ppm.    This  is  well  below  International  Pharmaceutical  Standard  of   0.1  ppm.    Further  analysis  by  Eurofins  showed  a  very  high  rate  -­‐  or  ease  -­‐  of  digestibility   (using  a  Pepsin  Test)  making  the  amino  acids  and  minerals  very  bio-­‐available.     Advance   Protein  Powder  has  a  long,  stable  shelf  life;  a  sample  produced  in  2005  and  tested  in  2012   showed  a  profile  consistent  with  a  current  batch  analysis.        
  • 8.                                   Julie  Spero,  MBA,  NC     8  of  15   Potential  for  Allergic  Response     All  three  protein  sources  discussed  here  are  among  the  top  eight  most  allergenic  foods   known.  These  eight  foods  include:   milk/dairy,  eggs,  soy,  peanuts,  tree  nuts,  shellfish,  finfish,   and  wheat  (in  no  particular  order).    Food  allergies  can  be  a  problem  for  people  and  in  some   cases  a  very  serious  one.    The  CDC's  (Centers  for  Disease  Control  and  Prevention)  National   Center  for  Health  Statistics  reports  that  these  foods  account  for  90  percent  of  all  food   allergies.    According  to  the  National  Institute  of  Health  (NIH),  allergy  to  eggs,  milk,  peanuts,   tree  nuts,  soy,  and  wheat  are  most  likely  to  occur  in  children.    In  Adults,  the  most  common   foods  that  cause  allergic  (anaphylaxis)  reactions  are  shellfish,  peanut  and  tree  nuts,  and  then   fish.     The  following  data  is  taken  in  part  from  a  report  from  FARE,  a  nonprofit  organization  for   Food  Allergy  Research  &  Education)  xvii   Peanuts:   0.6  -­‐  1.3%   Tree  nuts:   0.4  -­‐  0.6%   Fish:   0.4%   Crustacean  shellfish  (crab,  shrimp,  lobster...):   1.2%   All  seafood:   0.6%  in  children  and  2.8%  in  adults   Milk:   2.5%  in  young  children  and  0.2  -­‐  0.4%  in  general   population   Soy:   0.4%  in  children  and  0.1%  in  adults  xviii        
  • 9.                                   Julie  Spero,  MBA,  NC     9  of  15     Potential  retail  food  uses  for  APP  include:     • Food  bars  with  a  varied  protein,  fat,  &  carbohydrate  ratios  and  ingredients   o Sports  nutrition:    bodybuilders,  climbers,  runners,  etc.  for  both  pre  and  post   workout.    Private  label  options  for  gyms  and  athletic  clubs   o Snacks:    healthy  alternatives  for  kids  and  adults   o Specialty:    blood  sugar  regulation  and  weight  loss   • Drink  powder  blends  and  pre-­‐blended  drinks   o Formulation  options  for  the  categories  listed  above  with  higher  protein  and   additional  nutrition  potential  than  possible  in  bars   o Meal  replacement  "on  the  go"  drinks  for  regular  use   o Meal  replacement  drinks  or  blends  for  weight  loss  and  detoxification   o Geriatric  nutrition  drinks   o Balanced  nutrition  during  pregnancy     Potential  therapeutic  uses  for  APP  include:     • Rapidly  reversing  the  effects  of  severe  malnutrition  in  children  and  adults  in   global  hotspots   • Clinical  use  in  a  physical  therapy  setting  to  assist  in  bone  and  tissue  growth   after  injury  and  surgery   • As  a  nutritional  supplement  and  calcium  source  for  people  with  osteopenia   and  osteoporosis   • To  reduce  incidence  of  sarcopenia  in  the  aged  and  infirm   • As  a  superior  protein  source  in  a  hospital  or  rehabilitation  setting  to  replace   the  soy  protein  in  widely  available  pre-­‐made  "nutrition"  drinks      
  • 10.                                   Julie  Spero,  MBA,  NC     10  of  15   In  Summary     Advance  Protein  Powder  is  an  exciting  new  product  and  proprietary  process  technology  with   high  potential  as  an  all-­‐natural  protein/mineral  supplement,  in  multiple  retail  food  products,   and  for  use  in  therapeutic  nutritional  therapies.    APP  is  comparable  in  BV  value  to  the  best   quality  whey  protein  products  on  the  market  and  superior  in  balanced  nutrition  due  to  the   unique  amino  acid  profile  and  abundance  of  naturally  occurring  organically  bound  minerals   found  in  fish.        Julie  Spero,  MBA,  NC      President   i  “Nutrition  and  Energy  Bars  “Wise  Traditions  in  Food,  Farming  and  the  Healing  Arts”.  Weston   A.  Price  Foundation,  Winter  2002.  http://www.westonaprice.org/index.html       ii Fernandez-­‐Corenego,  Jorge.  USDA,  National  Agricultural  Statistics  Servce,  “Recent  Trends  in   GE  Adoption.”  Last  modified  07/05/2012.  http://www.ers.usda.gov/data-­‐products/adoption-­‐ of-­‐genetically-­‐engineered-­‐crops-­‐in-­‐the-­‐us/recent-­‐trends-­‐in-­‐ge-­‐adoption.aspx.       iii Daniel,  PhD,  CCN,  Kaayla  T.  The  Whole  Soy  Story.  Washington,  DC:  New  Trends  Publishing,   Inc.,  2005.   iv Jane  E.  Kerstetter,  Kimberly  O.  O'Brien,  and  Karl  L.  Insogna,  "Low  Protein  Intake:  The  impact   of  Calcium  and  Bone  Homeostasis  in  Humans,"  The  Journal  of  Nutrition,  133,  no.  3  (2003):   8555-­‐8615.     v Beauchamp,  Kimberley,  ND.  Bastyr  Center  for  Natural  Health,  “Calcium  Reduces  High  Blood   Pressure.”  Last  modified  2006.  http://www.bastyrcenter.org/content/view/1029.       vi Alastra,  Holly.  “The  Role  of  Calcium  in  the  Bones  and  Immune  System.”  Last  modified  2011.   http://www.livestrong.com/article/526824-­‐the-­‐role-­‐of-­‐calcium-­‐in-­‐the-­‐bones-­‐and-­‐immune-­‐ system/.       vii Université  Laval  (2009,  March  19).  “Diet  Rich  in  Calcium  Aids  Weight  Loss  in  People  with   Calcium  Deficient  Diets”.  Science  Daily.       viii N.  Bergeron,  H.  Jacques,  “Influence  of  fish  protein  as  compared  to  casein  and  soy  protein  on  
  • 11.                                   Julie  Spero,  MBA,  NC     11  of  15   serum  and  liver  lipids,  and  serum  lipoprotein  cholesterol  levels  in  the  rabbits”.   Atherosclerosis,  August,  no.  78  (1989):  113-­‐21.       ix N.  Bergeron,  Y.  Deshailes,  H.  Jacques,  “Factorial  experiment  to  determine  influence  of  fish   protein  and  fish  oil  on  serum  and  liver  lipids  in  rabbits”.  Nutrition,  Sept-­‐Oct,  no.  8  (1992):   354-­‐8     x D.  Ait-­‐Yahia,  et  al,  “Dietary  fish  protein  lowers  blood  pressure  and  alters  tissue   polyunsaturated  fatty  acid  composition  in  spontaneously  hypertensive  rats.,”  Nutrition,   April,  no.  19  (2003):  342-­‐6     xi D.  Ait-­‐Yahia,  et  al,  “Fish  protein  improves  blood  pressure  but  alters  HDL2  and  HDL3   composition  and  tissue  lipoprotein  lipase  activities  in  spontaneously  hypertensive  rats.,”   European  Journal  of  Nutrition,  44,  no.  (2005):  10-­‐15   xii Veronique  Oullet,  et  al,  “Dietary  Cod  Protein  Reduces  Plasma  C-­‐Reactive  Protein  in  Insulin-­‐ Resistant  Men  and  Women,”  The  Journal  of  Nutrition,  138,  no.  December  (2008):  2386-­‐2391.     xiii T  Kawasaki,  “Antihypertensive  effect  and  safety  evaluation  of  vegetable  drink  with  peptides   derived  from  sardine  protein  hydrolysates  on  mild  hypertensive,  high-­‐normal  and  normal   blood  pressure  subjects,”  Center  for  Health  and  Sports  Science,  93,  no.  Oct  (2002):  208-­‐18     xiv Hong-­‐gang  Tang,  et  al,  “Effects  of  fish  protein  hydrolysate  on  growth  performance  and   humoral  immune  response  in  large  yellow  croaker  (Pseudosciaena  crocea  R.),”  Journal  of   Zhejiang  University  SCIENCE  B,  9,  no.9  (2008):  684-­‐690.   xv Crystal  D.  Cinq-­‐Mars,  “Investigations  into  inhibitor  Type  and  Mode,  Simulated   Gastrointestinal  Digestion  and  Cell  Transport  of  the  Angiotensin  I-­‐Converting  Enzyme-­‐ Inhibitory  Peptides  in  Pacific  Hake  (Merluccius  productus)  Fillet  Hydrolysate,”  Journal  of   Agricultural  and  Food  Chemistry,  52,  no.  2  (2008):  410-­‐410   xvi Ouellet,  Veronique,  Julie  Marois,  and  S.  John  Weisnagel.  "Dietary  Cod  Protein  Improves   Insulin  Sensitivity  in  Insulin-­‐Resistant  Men  and  Women."  Diabetes  Care.  no.  11  (2007):  2816-­‐ 2821.     xvii FARE:  Food  Allergy  Research  &  Education,  “Food  Allergy  Facts  and  Statistics  for  the  U.S.”  Last   modified  10/3/2011.  http://www.foodallergy.org/document.doc?id=194.       xviii Savage  JH,  Kaeding  AJ,  Matsui  EC,  Wood  RA.  The  natural  history  of  soy  allergy.  J  Allergy  Clin   Immunol,  2010;125:683-­‐86    
  • 12.                                   Julie  Spero,  MBA,  NC     12  of  15     AMINO  ACID  COMPOSITION  WITH  COMPARISON  GRAPHS           Advance   Protein   Powder   *   Blue   Wave   Source   Organic   Whey   American   Whey   Whey-­‐ Isolate   NutriBio   Whey   NutriBio   Soy   Bulk   Soy   Isolate   Essential   Histidine   0.36   0.21   0.23   0.48   0.47   0.42   0.66   NA   Isoleucine*   0.59   0.54   1.17   1.87   1.75   1.58   1.24   1.50   Leucine*   1.02   1.01   2.42   2.63   3.03   2.74   2.07   2.50   Lysine*   1.14   0.93   1.95   2.20   3.03   2.74   1.58   NA   Methionine   0.73   0.45   0.50   0.65   0.63   0.57   0.35   0.41   Phenylalanine   0.54   0.57   0.47   0.88   0.91   0.82   1.32   NA   Threonine   0.63   0.72   1.71   1.80   1.91   1.72   0.95   1.16   Tryptophan   0.31   0.60   0.23   0.51   0.50   0.45   0.35   0.38   Valine   0.67   0.70   1.03   1.48   1.44   1.30   1.26   1.50   NonEssential   Alanine   0.85   1.12   0.94   1.27   1.44   1.30   1.09   1.34   Arginine   0.87   1.15   0.31   0.08   0.66   0.59   1.93   2.34   Aspartic  Acid   1.33   1.43   2.50   3.45   3.03   2.74   2.93   3.59   Cysteine   0.24   0.70   0.08   0.75   0.81   0.73   0.32   0.38   Glutamic  Acid   1.93   2.11   5.32   4.70   NA   4.83   4.86   NA   Glycine   0.74   2.03   0.39   0.48   NA   0.45   1.06   NA   Proline   0.55   1.02   1.48   1.54   1.72   1.55   1.29   1.63   Serine   0.48   0.98   1.09   1.28   1.16   1.05   1.32   1.69   Tyrosine   0.45   0.46   0.47   0.69   0.84   0.76   0.98   NA   *  All  Advance  International,  Inc  products  are  third-­‐party  tested  for  quality  by  Eurofins  Scientific   S.E.        
  • 13.                                   Julie  Spero,  MBA,  NC     13  of  15       0.00   1.00   2.00   3.00   4.00   5.00   6.00   Advance  Protein  Powder  *   BlueWave   Source  Organic  Whey   American  Whey   Whey-­‐Isolate   NutriBio  Whey   NutriBio  Soy   Bulk  Soy  Isolate   AMINO  ACID  COMPARISON  PER  25  GRAMS   OF  PROTEIN  
  • 14.                                   Julie  Spero,  MBA,  NC     14  of  15         MINERAL  COMPOSITION     RDA       MINERALS   APP  *   BlueWav e   Source   Organic   Whey   America n  Whey   Whey-­‐ Isolate   NutriBi o  Whey   NutriBi o  Soy   Bulk   Soy   Isolat e   100 0   mg   Calcium   64.3%   12.5%   11.9%   12.0%   12.5%   14.0%   5.7%   4.7%   18   mg   Iron   21.3%   0%   0%   0%   0%   0%   22.2%   18.2 %   400   mg   Magnesiu m   11.7%   0%   9.5%   0%   0%   5.0%   0%   4.9%   15   mg   Zinc   11.7%   0%   0%   0%   0%   0%   0%   0%   70   mc g   Selenium   0.1%   0%   0%   0%   0%   0%   0%   0%   2   mg   Copper   6.7%   0%   0%   0%   0%   0%   0%   0%   120   mc g   Chromium   0.1%   0%   0%   0%   0%   0%   0%   0%   240 0   mg   Sodium   2.4%   0%   0%   1.8%   0%   0%   16.8%   10.4 %   350 0   mg   Potassium   4.5%   0%   0%   2.4%   0%   0%   0%   7.1%   100 0   mg   Phosphoru s   18.4%   0%   9.5%   5.9%   0%   6.0%   0%   26.6 %   *  All  Advance  International,  Inc  products  are  third-­‐party  tested  for  quality  by  Eurofins  Scientific  S.E.  
  • 15.                                   Julie  Spero,  MBA,  NC     15  of  15   0.0%   10.0%   20.0%   30.0%   40.0%   50.0%   60.0%   70.0%   APP  *   BlueWave   Source  Organic  Whey   American  Whey   Whey-­‐Isolate   NutriBio  Whey   NutriBio  Soy   Bulk  Soy  Isolate   Mineral  Content  as  a  percentage  of  RDA  in  25grams  of  protein  
  • 16.                                   Julie  Spero,  MBA,  NC     16  of  15