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Lawrence Oresanya MD                             Lower Extremity Revascularization in
                                               Shoujun Zhao MD, PhD
                                             Emily Finlayson MD, MS
                                       Phillip R Lee Institute for Health Policy Studies
       Department of Surgery, University of California San Francisco, San Francisco CA
                                                                                               Nursing Home Residents in the United
                                                                                               States
                                                                                                        Introduction
                                                                                                            • For patients with peripheral arterial disease (PAD), the main goals of lower extremity revascularization (LER) are
                                                                                                            to prevent limb loss and allow patients to maintain functional independence
                                                                                                            • Prior studies suggest that patients who are non-ambulatory and functionally dependent have poor outcomes
                                                                                                            •Outcomes after lower extremity revascularization in the frailest elders – nursing home residents – are poorly
                                                                                                            understood

                                                                                                            Methods/Approach
                                                                                                            • Usingdata from a national registry of nursing home residents (Minimum Data Set for Nursing Homes (MDS)) and
                                                                                                            Medicare claims, we identified all nursing home residents who underwent lower extremity revascularization
                                                                                                            procedures in the United States between 2005 and 2008 (n=10809)
                                                                                                            • Based on registry data, patients were classified as ambulatory, non-ambulatory (63%) and bed bound (27%)and
                                                                                                            functional status assessed with the MDS-ADL score
                                                                                                            • We examined functional trajectories before and after surgery using cubic spline trajectory modeling techniques
                                                                                                            •The intervention was considered a ‘success’ at 1 year if the resident was alive and had no lower extremity
                                                                                                            complications (re-intervention and/or above ankle amputation)




Techniques for Lower Extremity                                                                          Functional Status after Revascularization
Revascularization                                                                                                                        All residents                                                                                                                                               Non ambulatory
                                                                                                                    100




                                                                                                                                                                                                                                                                               100
                                                                                                                           Improve          Improve           Improve          Improve                                                                                                   Improve          Improve                Improve         Improve
                                                                                                                                                                                                      Percentage (%)
                                                                                           Percentage (%)




                                                                                                                             ADL              ADL               ADL              ADL                                                                                                       ADL              ADL                    ADL             ADL

             Surgical Bypass Graft                                                                                         Maintain         Maintain          Maintain         Maintain
                                                                                                                                                                                 ADL                                                                                                     Maintain         Maintain               Maintain        Maintain
                                                                                                                                                                                                                                                                                                                                                   ADL
                                                                                                                    80




                                                                                                                                             ADL               ADL                                                                                                             80                                                 ADL
                                                                                                                            ADL                                                                                                                                                           ADL              ADL

                                                                                                                                                                                                                                                                                                                                                   ADL
                                                                                                                                                                                                                                                                                                                                  ADL
                                                                                                                    60




                                                                                                                                                                                                                                                                                                                                                  decline
                                                                                                                                                                                                                                                                               60



                                                                                                                                              ADL              ADL              ADL                                                                                                                        ADL
                                                                                                                             ADL                                                                                                                                                                                                 decline
                                                                                                                                             decline          decline          decline                                                                                                    ADL             decline
                                                                                                                            decline
                                                                                                                                                                                                                                                                                         decline
                                                                                                                    40




                                                                                                                                                                                                                                                                               40
                                                                                                                    20




                                                                                                                                                                                                                                                                               20




                                                                                                                            Died              Died             Died                                                                                                                       Died                Died                Died             Died
                                                                                                                                                                                 Died
                                                                                                                    0




                                                                                                                                                                                                                                                                               0




                                                                                                                           3M.               6M.              9M.             12M.         Died                                                                                          3M.              6M.                    9M.         12M.
                                                                                                                                                                                               Died



                                                                                                                                           Bedbound
                                                                                                                                                                                                                                                                               12
                                                                                                                    100




                                                                                                                            Improve         Improve           Improve          Improve
                                                                                           Percentage (%)




                                                                                                                              ADL             ADL               ADL              ADL                                                                                                                                 All residents
                                                                                                                                                                                                                                                                               14




                                                                                                                                                                                                                                                                                                                     Nonambulatory residents
                                                                                                                                                                                                                       MDS-ADL Score




                                                                                                                                                                               Maintain
                                                                                                                                                              Maintain                                                                                                                                               Nonambulatory & unable to transfer
                                                                                                                    80




                                                                                                                           Maintain         Maintain                            ADL
                                                                                                                                                                                                                                                                               16




                                                                                                                            ADL              ADL               ADL
                                                                                                                                                                                 ADL
                                                                                                                                                                ADL             decline
                                                                                                                                                                                                                                                                               18
                                                                                                                    60




                                                                                                                                              ADL              decline
                                                                                                                             ADL             decline
                                                                                                                                                                                                                                                                               20




                                                                                                                            decline
                                                                                                                    40




                                                                                                                                                                                                                                                                               22
                                                                                                                                                                                                                       Survival & No-ampulation & No-reintervention Rate (%)
                                                                                                                    20




                                                                                                                                                                                                                                                                               24




                                                                                                                             Died             Died             Died              Died
                                                                                                                                                                                                                                                                               26
                                                                                                                    0




                                                                                                                                                                                                                                                                                                      0                      5                   10
                                                                                                                           3M.               6M.              9M.             12M.
                                                                                                                                                                                                                                                                                                                     Months
                                                                                                                                                                                                                                                                               100




  Endovascular stent (‘minimally invasive’)
                                                                                                                                                                                                                                                                               80




                                                                                                                “Success” at One
                                                                                                                                                                                                                                                                               60




                                                                                                                Year after Surgery
                                                                                                                                                                                                                                                                               40
                                                                                                                                                                                                                                                                               20




                                                                                                                                                                                                                                                                                                                 All residents
                                                                                                                                                                                                                                                                                                                 Nonambulatory residents
                                                                                                                                                                                                                                                                                                                 Nonambulatory & unable to transfer
                                                                                                                                                                                                                                                                               0




                                                                                                                                                                                                                                                                                     0           2        4             6            8      10              12

                                                                                                                                                                                                                                                                                                                     Months

                                                                                                            Conclusions
                                                                                                        •Alarge number of nursing home residents with relative contraindications to revascularization (non-
                                                                                                        ambulatory/bedbound) are undergoing lower extremity revascularization in the United States

                                                                                                        • Only a small proportion of nursing home residents appear to maintain or improve function after revascularization

                                                                                                        • Policies and interventions aimed at improving patient selection are needed to guide use of this potentially morbid
                                                                                                        and resource intensive intervention in this vulnerable population


                                                                                                        ACKNOWLEDGEMENTS:
                                                                                                        Funding for this project was provided by the Paul Beeson Career Development Award In Aging Research and the Philip R. Lee Post-Doctoral Fellowship in Health Policy

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Lower Extremity Revascularization in Nursing Home Residents in the United States

  • 1. Lawrence Oresanya MD Lower Extremity Revascularization in Shoujun Zhao MD, PhD Emily Finlayson MD, MS Phillip R Lee Institute for Health Policy Studies Department of Surgery, University of California San Francisco, San Francisco CA Nursing Home Residents in the United States Introduction • For patients with peripheral arterial disease (PAD), the main goals of lower extremity revascularization (LER) are to prevent limb loss and allow patients to maintain functional independence • Prior studies suggest that patients who are non-ambulatory and functionally dependent have poor outcomes •Outcomes after lower extremity revascularization in the frailest elders – nursing home residents – are poorly understood Methods/Approach • Usingdata from a national registry of nursing home residents (Minimum Data Set for Nursing Homes (MDS)) and Medicare claims, we identified all nursing home residents who underwent lower extremity revascularization procedures in the United States between 2005 and 2008 (n=10809) • Based on registry data, patients were classified as ambulatory, non-ambulatory (63%) and bed bound (27%)and functional status assessed with the MDS-ADL score • We examined functional trajectories before and after surgery using cubic spline trajectory modeling techniques •The intervention was considered a ‘success’ at 1 year if the resident was alive and had no lower extremity complications (re-intervention and/or above ankle amputation) Techniques for Lower Extremity Functional Status after Revascularization Revascularization All residents Non ambulatory 100 100 Improve Improve Improve Improve Improve Improve Improve Improve Percentage (%) Percentage (%) ADL ADL ADL ADL ADL ADL ADL ADL Surgical Bypass Graft Maintain Maintain Maintain Maintain ADL Maintain Maintain Maintain Maintain ADL 80 ADL ADL 80 ADL ADL ADL ADL ADL ADL 60 decline 60 ADL ADL ADL ADL ADL decline decline decline decline ADL decline decline decline 40 40 20 20 Died Died Died Died Died Died Died Died 0 0 3M. 6M. 9M. 12M. Died 3M. 6M. 9M. 12M. Died Bedbound 12 100 Improve Improve Improve Improve Percentage (%) ADL ADL ADL ADL All residents 14 Nonambulatory residents MDS-ADL Score Maintain Maintain Nonambulatory & unable to transfer 80 Maintain Maintain ADL 16 ADL ADL ADL ADL ADL decline 18 60 ADL decline ADL decline 20 decline 40 22 Survival & No-ampulation & No-reintervention Rate (%) 20 24 Died Died Died Died 26 0 0 5 10 3M. 6M. 9M. 12M. Months 100 Endovascular stent (‘minimally invasive’) 80 “Success” at One 60 Year after Surgery 40 20 All residents Nonambulatory residents Nonambulatory & unable to transfer 0 0 2 4 6 8 10 12 Months Conclusions •Alarge number of nursing home residents with relative contraindications to revascularization (non- ambulatory/bedbound) are undergoing lower extremity revascularization in the United States • Only a small proportion of nursing home residents appear to maintain or improve function after revascularization • Policies and interventions aimed at improving patient selection are needed to guide use of this potentially morbid and resource intensive intervention in this vulnerable population ACKNOWLEDGEMENTS: Funding for this project was provided by the Paul Beeson Career Development Award In Aging Research and the Philip R. Lee Post-Doctoral Fellowship in Health Policy