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Anti microbial drugs
1.
2.
These are substances produced by
microorganisms, chemical synthesis, &
natural substance, which selectively suppress
the growth of or kill other microorganisms at
low concentrations…..
4.
A) chemical structure
B) mechanism of action
C) type of organisms against which primarily
active
D) spectrum of activity
E) type of action
F) antibiotic are obtained from…..
8.
1) inhibit cell wall synthesis
2) cause leakage from cell membrane
3) inhibit protein synthesis
4) cause misreading f m RNA code and affect
permeability
5) inhibit DNA gyrase
6) interfere DNA fuction, syntesis
7) interfere in metabolism
16.
Clinical diagnosis itself directs choice of the
AMA
A good guess can be made
Choice to be based on bacteriological
examination
17.
Spectrum of activity
Type of activity
Sensitivity of the organism
Relative toxicity
Pharmacokinetics profile
Route of administration
Evidence of clinical efficacy
cost